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Multi-level remodeling of transcriptional landscapes in aging and longevity.

Lai R, Lu R, Danthi PS, Bravo J, Goumba A, Sampathkumar NK, Benayoun BA.

BMB Rep. 2018 Dec 11. pii: 4449. [Epub ahead of print]


HELLS regulates chromatin remodeling and epigenetic silencing of multiple tumor suppressor genes in human hepatocellular carcinoma.

Law CT, Wei L, Tsang FH, Chan CY, Xu IM, Lai RK, Ho DW, Lee JM, Wong CC, Ng IO, Wong CM.

Hepatology. 2018 Dec 5. doi: 10.1002/hep.30414. [Epub ahead of print]


Subdural empyema complicated with intracranial hemorrhage in a postradiotherapy nasopharyngeal carcinoma patient: A case report and review of literature.

Chen JC, Tan DH, Xue ZB, Yang SY, Li Y, Lai RL.

World J Clin Cases. 2018 Nov 26;6(14):825-829. doi: 10.12998/wjcc.v6.i14.825.


Lateral intraventricular anaplastic meningioma: a series of 5 patients at a single institution and literature review.

Chen H, Lai R, Tang X, Liu Z, Xu J.

World Neurosurg. 2018 Nov 27. pii: S1878-8750(18)32743-8. doi: 10.1016/j.wneu.2018.11.184. [Epub ahead of print]


Prolonged milk provisioning in a jumping spider.

Chen Z, Corlett RT, Jiao X, Liu SJ, Charles-Dominique T, Zhang S, Li H, Lai R, Long C, Quan RC.

Science. 2018 Nov 30;362(6418):1052-1055. doi: 10.1126/science.aat3692.


Aspirin, Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), and Glioma Risk: Original Data from the Glioma International Case-Control Study and a Meta-Analysis.

Amirian ES, Ostrom QT, Armstrong GN, Lai RK, Gu X, Jacobs DI, Jalali A, Claus EB, Barnholtz-Sloan JS, Il'yasova D, Schildkraut JM, Ali-Osman F, Sadetzki S, Jenkins RB, LaChance DH, Olson SH, Bernstein JL, Merrell RT, Wrensch MR, Johansen C, Houlston RS, Scheurer ME, Shete S, Amos CI, Melin B, Bondy ML.

Cancer Epidemiol Biomarkers Prev. 2018 Nov 27. pii: cebp.0702.2018. doi: 10.1158/1055-9965.EPI-18-0702. [Epub ahead of print]


Induction of Autonomous Memory Alveolar Macrophages Requires T Cell Help and Is Critical to Trained Immunity.

Yao Y, Jeyanathan M, Haddadi S, Barra NG, Vaseghi-Shanjani M, Damjanovic D, Lai R, Afkhami S, Chen Y, Dvorkin-Gheva A, Robbins CS, Schertzer JD, Xing Z.

Cell. 2018 Nov 29;175(6):1634-1650.e17. doi: 10.1016/j.cell.2018.09.042. Epub 2018 Oct 25.


Cancer antigen-125 and outcomes in acute heart failure: a systematic review and meta-analysis.

Li KHC, Gong M, Li G, Baranchuk A, Liu T, Wong MCS, Jesuthasan A, Lai RWC, Lai JCL, Lee APW, Bayés-Genis A, de la Espriella R, Sanchis J, Wu WKK, Tse G, Nuñez J; International Health Informatics Study (IHIS) Network.

Heart Asia. 2018 Oct 26;10(2):e011044. doi: 10.1136/heartasia-2018-011044. eCollection 2018.


18F-FDG PET/CT Imaging in an Adolescent Patient With Primary Prostatic Stromal Sarcoma.

Lai R, Ding C.

Clin Nucl Med. 2019 Jan;44(1):45-47. doi: 10.1097/RLU.0000000000002372.


Design and implementation of pragmatic clinical trials using the electronic medical record and an adaptive design.

Simon KC, Tideman S, Hillman L, Lai R, Jathar R, Ji Y, Bergman-Bock S, Castle J, Franada T, Freedom T, Marcus R, Mark A, Meyers S, Rubin S, Semenov I, Yucus C, Pham A, Garduno L, Szela M, Frigerio R, Maraganore DM.

JAMIA Open. 2018 Jul;1(1):99-106. doi: 10.1093/jamiaopen/ooy017. Epub 2018 Jun 11.


Isolation and Characterization of Poecistasin, an Anti-Thrombotic Antistasin-Type Serine Protease Inhibitor from Leech Poecilobdella manillensis.

Tang X, Chen M, Duan Z, Mwangi J, Li P, Lai R.

Toxins (Basel). 2018 Oct 26;10(11). pii: E429. doi: 10.3390/toxins10110429.


Targeting surface nucleolin induces autophagy-dependent cell death in pancreatic cancer via AMPK activation.

Xu C, Wang Y, Tu Q, Zhang Z, Chen M, Mwangi J, Li Y, Jin Y, Zhao X, Lai R.

Oncogene. 2018 Oct 24. doi: 10.1038/s41388-018-0556-x. [Epub ahead of print]


The defensive system of tree frog skin identified by peptidomics and RNA sequencing analysis.

Rong M, Liu J, Liao Q, Lin Z, Wen B, Ren Y, Lai R.

Amino Acids. 2018 Oct 23. doi: 10.1007/s00726-018-2670-z. [Epub ahead of print]


Immune regulatory targets of mesenchymal stromal cell exosomes/small extracellular vesicles in tissue regeneration.

Toh WS, Zhang B, Lai RC, Lim SK.

Cytotherapy. 2018 Dec;20(12):1419-1426. doi: 10.1016/j.jcyt.2018.09.008. Epub 2018 Oct 20. Review.


The influence of C2C3 double bond on the antiradical activity of flavonoid: Different mechanisms analysis.

Zheng YZ, Deng G, Chen DF, Guo R, Lai RC.

Phytochemistry. 2019 Jan;157:1-7. doi: 10.1016/j.phytochem.2018.10.015. Epub 2018 Oct 17.


Epstein-Barr virus associated smooth muscle tumors in solid organ transplant recipients: Incidence over 31 years at a single institution and review of the literature.

Stubbins RJ, Alami Laroussi N, Peters AC, Urschel S, Dicke F, Lai RL, Zhu J, Mabilangan C, Preiksaitis JK.

Transpl Infect Dis. 2018 Oct 9:e13010. doi: 10.1111/tid.13010. [Epub ahead of print]


Occurrence of Highly Conjugative IncX3 Epidemic Plasmid Carrying bla NDM in Enterobacteriaceae Isolates in Geographically Widespread Areas.

Wang Y, Tong MK, Chow KH, Cheng VC, Tse CW, Wu AK, Lai RW, Luk WK, Tsang DN, Ho PL.

Front Microbiol. 2018 Sep 20;9:2272. doi: 10.3389/fmicb.2018.02272. eCollection 2018.


Centipede envenomation: Clinical importance and the underlying molecular mechanisms.

Ombati R, Luo L, Yang S, Lai R.

Toxicon. 2018 Nov;154:60-68. doi: 10.1016/j.toxicon.2018.09.008. Epub 2018 Sep 29. Review.


Electrocardiographic conduction and repolarization markers associated with sudden cardiac death: moving along the ECG waveform.

Reynard JT, Oshodi OM, Lai J, Lai R, Bazoukis G, Fragakis N, Letsas KP, Korantzopoulos P, Liu FZ, Liu T, Xia Y, Tse G, Li KH.

Minerva Cardioangiol. 2018 Sep 26. doi: 10.23736/S0026-4725.18.04775-8. [Epub ahead of print]


Hypoxia Induces the Acquisition of Cancer Stem-like Phenotype Via Upregulation and Activation of Signal Transducer and Activator of Transcription-3 (STAT3) in MDA-MB-231, a Triple Negative Breast Cancer Cell Line.

Soleymani Abyaneh H, Gupta N, Alshareef A, Gopal K, Lavasanifar A, Lai R.

Cancer Microenviron. 2018 Dec;11(2-3):141-152. doi: 10.1007/s12307-018-0218-0. Epub 2018 Sep 25.


Ischemic colitis caused by polycythemia vera: A case report and literature review.

Zhang S, Lai R, Gao X, Zhao Y, Zhao Y, Wu J, Guo Z.

Exp Ther Med. 2018 Oct;16(4):3663-3667. doi: 10.3892/etm.2018.6638. Epub 2018 Aug 22.


Use of an Electronic Medical Record to Track Adherence to the Mediterranean Diet in a US Neurology Clinical Practice.

Rasmussen E, Fosnacht Morgan AM, Munson R, Ong A, Patel S, Yucus C, Pham A, Patel V, Frigerio R, Lai R, Hillman L, Tideman S, Wang C, Simon KC, Martínez-González MÁ, Maraganore DM.

Mayo Clin Proc Innov Qual Outcomes. 2018 Feb 1;2(1):49-59. doi: 10.1016/j.mayocpiqo.2017.12.003. eCollection 2018 Mar.


Adding the T to ADME: Predictive Toxicity in Renal Drug Development.

Lai RE, Masereeuw R.

AAPS J. 2018 Sep 5;20(6):98. doi: 10.1208/s12248-018-0258-x. No abstract available.


Membrane Lipids Define Small Extracellular Vesicle Subtypes Secreted By Mesenchymal Stromal Cell.

Lai RC, Lim SK.

J Lipid Res. 2018 Aug 28. pii: jlr.R087411. doi: 10.1194/jlr.R087411. [Epub ahead of print]


Age-specific genome-wide association study in glioblastoma identifies increased proportion of 'lower grade glioma'-like features associated with younger age.

Ostrom QT, Kinnersley B, Armstrong G, Rice T, Chen Y, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Eckel-Passow JE, Il'yasova D, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Rubin JB, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M; GliomaScan consortium, Houlston RS, Jenkins RB, Wrensch MR, Melin B, Bondy ML, Barnholtz-Sloan JS.

Int J Cancer. 2018 Nov 15;143(10):2359-2366. doi: 10.1002/ijc.31759. Epub 2018 Sep 19.


Corticosteroids as an adjunct to tuberculosis therapy.

Schutz C, Davis AG, Sossen B, Lai RP, Ntsekhe M, Harley YX, Wilkinson RJ.

Expert Rev Respir Med. 2018 Oct;12(10):881-891. doi: 10.1080/17476348.2018.1515628. Epub 2018 Sep 6.


Enhanced autophagy contributes to protective effects of IL-22 against acetaminophen-induced liver injury.

Mo R, Lai R, Lu J, Zhuang Y, Zhou T, Jiang S, Ren P, Li Z, Cao Z, Liu Y, Chen L, Xiong L, Wang P, Wang H, Cai W, Xiang X, Bao S, Xie Q.

Theranostics. 2018 Jul 30;8(15):4170-4180. doi: 10.7150/thno.25798. eCollection 2018.


Sex-specific gene and pathway modeling of inherited glioma risk.

Ostrom QT, Coleman W, Huang W, Rubin JB, Lathia JD, Berens ME, Speyer G, Liao P, Wrensch MR, Eckel-Passow JE, Armstrong G, Rice T, Wiencke JK, McCoy LS, Hansen HM, Amos CI, Bernstein JL, Claus EB, Houlston RS, Il'yasova D, Jenkins RB, Johansen C, Lachance DH, Lai RK, Merrell RT, Olson SH, Sadetzki S, Schildkraut JM, Shete S, Andersson U, Rajaraman P, Chanock SJ, Linet MS, Wang Z, Yeager M; GliomaScan consortium, Melin B, Bondy ML, Barnholtz-Sloan JS.

Neuro Oncol. 2018 Aug 14. doi: 10.1093/neuonc/noy135. [Epub ahead of print]


[Cp*RhIII ]/Ionic Liquid as a Highly Efficient and Recyclable Catalytic Medium for C-H Amidation.

Ma Q, Yu X, Lai R, Lv S, Dai W, Zhang C, Wang X, Wang Q, Wu Y.

ChemSusChem. 2018 Oct 24;11(20):3672-3678. doi: 10.1002/cssc.201801287. Epub 2018 Sep 25.


Small Biopsies Misclassify up to 35% of PD-L1 Assessments in Advanced Lung Non-Small Cell Lung Carcinomas.

Bigras G, Mairs S, Swanson PE, Morel D, Lai R, Izevbaye I.

Appl Immunohistochem Mol Morphol. 2018 Nov/Dec;26(10):701-708. doi: 10.1097/PAI.0000000000000698.


The impact of photofunctionalized gold nanoparticles on osseointegration.

Elkhidir Y, Lai R, Feng Z.

Heliyon. 2018 Jul 24;4(7):e00662. doi: 10.1016/j.heliyon.2018.e00662. eCollection 2018 Jul.


Effects of redox label location on the performance of an electrochemical aptamer-based tumor necrosis factor-alpha sensor.

Mayer MD, Lai RY.

Talanta. 2018 Nov 1;189:585-591. doi: 10.1016/j.talanta.2018.07.055. Epub 2018 Jul 18.


Structured Clinical Documentation to Improve Quality and Support Practice-Based Research in Headache.

Meyers S, Claire Simon K, Bergman-Bock S, Campanella F, Marcus R, Mark A, Freedom T, Rubin S, Semenov I, Lai R, Hillman L, Tideman S, Pham A, Frigerio R, Maraganore DM.

Headache. 2018 Sep;58(8):1211-1218. doi: 10.1111/head.13348. Epub 2018 Aug 1.


Highly Active C8-Acyl-ACP Thioesterase Variant Isolated by a Synthetic Selection Strategy.

Hernández Lozada NJ, Lai RY, Simmons TR, Thomas KA, Chowdhury R, Maranas CD, Pfleger BF.

ACS Synth Biol. 2018 Sep 21;7(9):2205-2215. doi: 10.1021/acssynbio.8b00215. Epub 2018 Aug 21.


Molecular mechanism of the tree shrew's insensitivity to spiciness.

Han Y, Li B, Yin TT, Xu C, Ombati R, Luo L, Xia Y, Xu L, Zheng J, Zhang Y, Yang F, Wang GD, Yang S, Lai R.

PLoS Biol. 2018 Jul 12;16(7):e2004921. doi: 10.1371/journal.pbio.2004921. eCollection 2018 Jul.


MSC exosome works through a protein-based mechanism of action.

Toh WS, Lai RC, Zhang B, Lim SK.

Biochem Soc Trans. 2018 Aug 20;46(4):843-853. doi: 10.1042/BST20180079. Epub 2018 Jul 9. Review.


MicroRNA-599 suppresses glioma progression by targeting RAB27B.

Jiang Y, Wang X, Zhang J, Lai R.

Oncol Lett. 2018 Jul;16(1):1243-1252. doi: 10.3892/ol.2018.8727. Epub 2018 May 16.


Functional Plasticity of Gamma Delta T Cells and Breast Tumor Targets in Hypoxia.

Siegers GM, Dutta I, Lai R, Postovit LM.

Front Immunol. 2018 Jun 15;9:1367. doi: 10.3389/fimmu.2018.01367. eCollection 2018.


On-Surface Reactions in the Growth of High-Quality CdSe Nanocrystals in Nonpolar Solutions.

Lai R, Pu C, Peng X.

J Am Chem Soc. 2018 Jul 25;140(29):9174-9183. doi: 10.1021/jacs.8b04743. Epub 2018 Jul 12.


Lipid Emulsion Pretreatment Decreased the Maximum Total and Free Plasma Concentration of Levobupivacaine for Femoral and Sciatic Nerve Block in Below-Knee Fracture Surgery.

Chen Y, Zhang J, Chen Z, Wang Q, Li B, Lai R, Xu X, Cao Z, Yu L.

Reg Anesth Pain Med. 2018 Nov;43(8):838-843. doi: 10.1097/AAP.0000000000000834.


Constitutive Activation of STAT3 in Myeloma Cells Cultured in a Three-Dimensional, Reconstructed Bone Marrow Model.

Huang YH, Molavi O, Alshareef A, Haque M, Wang Q, Chu MP, Venner CP, Sandhu I, Peters AC, Lavasanifar A, Lai R.

Cancers (Basel). 2018 Jun 16;10(6). pii: E206. doi: 10.3390/cancers10060206.


The Design of Elderly Fracture Rehabilitation Software Based on "Information-Motivation-Behavioral Skills Model".

Wu Q, Jiang Z, Su T, Dai Y, Huang D, Lai R, Zhang J, Song L.

Stud Health Technol Inform. 2018;250:234.


ERK is a negative feedback regulator for IFN-γ/STAT1 signaling by promoting STAT1 ubiquitination.

Zhang Y, Chen Y, Liu Z, Lai R.

BMC Cancer. 2018 May 31;18(1):613. doi: 10.1186/s12885-018-4539-7.


Pruritus: Progress toward Pathogenesis and Treatment.

Song J, Xian D, Yang L, Xiong X, Lai R, Zhong J.

Biomed Res Int. 2018 Apr 11;2018:9625936. doi: 10.1155/2018/9625936. eCollection 2018. Review.


Effective cardiac radiotherapy relieved life-threatening heart failure caused by advanced small cell lung cancer with cardiac metastasis: a case report.

Chen CF, Lin MH, Chu KA, Liu WS, Hsiao SH, Lai RS.

J Thorac Dis. 2018 Apr;10(4):E250-E254. doi: 10.21037/jtd.2018.03.104.


Development and Characterization of an Anti-Acne Gel Containing Siamese Crocodile (Crocodylus siamensis) Leukocyte Extract.

Phupiewkham W, Lu Q, Payoungkiattikun W, Temsiripong T, Jangpromma N, Lai R, Klaynongsruang S.

J Microbiol Biotechnol. 2018 May 28;28(5):707-717. doi: 10.4014/jmb.1802.02027.


[Relevant factors of tinnitus in the elderly: an analysis of 150 volunteers].

Han L, Ma R, Wu XQ, Lin YJ, Jin YY, Yu LS, Lai RZ, Zeng L, Ma X.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Apr;32(8):587-591. doi: 10.13201/j.issn.1001-1781.2018.08.007. Chinese.


[The investigation rate and influence factors of tinnitus with chronic suppurative otitis media].

Lin YJ, Wu XQ, Ma X, Lai RZ.

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2018 Apr;32(8):579-583. doi: 10.13201/j.issn.1001-1781.2018.08.005. Chinese.


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