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Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer.

Wang CY, Chiao CC, Phan NN, Li CY, Sun ZD, Jiang JZ, Hung JH, Chen YL, Yen MC, Weng TY, Chen WC, Hsu HP, Lai MD.

Am J Cancer Res. 2020 Jan 1;10(1):95-113. eCollection 2020.


Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.

Ojha R, Nepali K, Chen CH, Chuang KH, Wu TY, Lin TE, Hsu KC, Chao MW, Lai MJ, Lin MH, Huang HL, Chang CD, Pan SL, Chen MC, Liou JP.

Eur J Med Chem. 2020 Jan 23;190:112086. doi: 10.1016/j.ejmech.2020.112086. [Epub ahead of print]


Serum metabolic characteristics and biomarker of early-stage heart failure.

Guo S, Kong J, Zhou D, Lai M, Chen Y, Xie D, Wang X, Wang D.

Biomark Med. 2020 Feb 14. doi: 10.2217/bmm-2019-0176. [Epub ahead of print]


Two-Step Patterning of Scalable All-Inorganic Halide Perovskite Arrays.

Lin CK, Zhao Q, Zhang Y, Cestellos-Blanco S, Kong Q, Lai M, Kang J, Yang P.

ACS Nano. 2020 Feb 14. doi: 10.1021/acsnano.9b09685. [Epub ahead of print]


Correction: Fusion of augmented reality imaging with the endoscopic view for endonasal skull base surgery; a novel application for surgical navigation based on intraoperative cone beam computed tomography and optical tracking.

Lai M, Skyrman S, Shan C, Babic D, Homan R, Edström E, Persson O, Burström G, Elmi-Terander A, Hendriks BHW, de With PHN.

PLoS One. 2020 Feb 13;15(2):e0229454. doi: 10.1371/journal.pone.0229454. eCollection 2020.


Paradoxical network excitation by glutamate release from VGluT3+ GABAergic interneurons.

Pelkey KA, Calvigioni D, Fang C, Vargish G, Ekins T, Auville K, Wester JC, Lai M, Mackenzie-Gray Scott C, Yuan X, Hunt S, Abebe D, Xu Q, Dimidschstein J, Fishell G, Chittajallu R, McBain CJ.

Elife. 2020 Feb 13;9. pii: e51996. doi: 10.7554/eLife.51996. [Epub ahead of print]


Neurogranin stimulates Ca2+/calmodulin-dependent kinase II by suppressing calcineurin activity at specific calcium spike frequencies.

Li L, Lai M, Cole S, Le Novère N, Edelstein SJ.

PLoS Comput Biol. 2020 Feb 12;16(2):e1006991. doi: 10.1371/journal.pcbi.1006991. [Epub ahead of print]


Long-term growth and bone development in children of HBV-infected mothers with and without fetal exposure to tenofovir disoproxil fumarate.

Wen WH, Chen HL, Ting-Fang Shih T, Wu JF, Ni YH, Lee CN, Zhao LL, Lai MW, Mu SC, Tung YC, Hsu HY, Chang MH; Taiwan Study Group for the Prevention of Mother-to-Infant Transmission of HBV (PreMIT study).

J Hepatol. 2020 Feb 7. pii: S0168-8278(20)30062-3. doi: 10.1016/j.jhep.2020.01.021. [Epub ahead of print]


Structural and spectral dynamics of single-crystalline Ruddlesden-Popper phase halide perovskite blue light-emitting diodes.

Chen H, Lin J, Kang J, Kong Q, Lu D, Kang J, Lai M, Quan LN, Lin Z, Jin J, Wang LW, Toney MF, Yang P.

Sci Adv. 2020 Jan 24;6(4):eaay4045. doi: 10.1126/sciadv.aay4045. eCollection 2020 Jan.


Quantitative digital pathology reveals association of cell-specific PNPLA3 transcription with NAFLD disease activity.

Sandhu B, Perez Matos MC, Tran S, Zhong A, Csizmadia E, Kim M, Herman MA, Nasser I, Lai M, Jiang ZG.

JHEP Rep. 2019 Jun 8;1(3):199-202. doi: 10.1016/j.jhepr.2019.05.007. eCollection 2019 Sep.


Relationship of Established Cardiovascular Risk Factors and Peripheral Biomarkers on Cognitive Function in Adults at Risk of Cognitive Deterioration.

Lai MMY, Sharman MJ, Ames DJ, Ellis KA, Cox KL, Hepworth G, Desmond P, Cyarto EV, Martins RN, Masters CL, Lautenschlager NT.

J Alzheimers Dis. 2020 Jan 28. doi: 10.3233/JAD-190953. [Epub ahead of print]


Identification of cellular microRNA miR-188-3p with broad-spectrum anti-influenza A virus activity.

Cui H, Zhang C, Zhao Z, Zhang C, Fu Y, Li J, Chen G, Lai M, Li Z, Dong S, Chen L, Li Z, Wang C, Liu J, Gao Y, Guo Z.

Virol J. 2020 Jan 30;17(1):12. doi: 10.1186/s12985-020-1283-9.


NeuroD1 overexpression in spinal neurons accelerates axonal regeneration after sciatic nerve injury.

Lai M, Pan M, Ge L, Liu J, Deng J, Wang X, Li L, Wen J, Tan D, Zhang H, Hu X, Fu L, Xu Y, Li Z, Qiu X, Chen G, Guo J.

Exp Neurol. 2020 Jan 25;327:113215. doi: 10.1016/j.expneurol.2020.113215. [Epub ahead of print]


LYW-6, a novel cryptotanshinone derived STAT3 targeting inhibitor, suppresses colorectal cancer growth and metastasis.

Wang H, Liu Z, Guan L, Li J, Chen S, Yu W, Lai M.

Pharmacol Res. 2020 Jan 23;153:104661. doi: 10.1016/j.phrs.2020.104661. [Epub ahead of print]


Open-Air Stereoselective Construction of C-Aryl Glycosides.

Lai M, Othman KA, Yao H, Wang Q, Feng Y, Huang N, Liu M, Zou K.

Org Lett. 2020 Feb 7;22(3):1144-1148. doi: 10.1021/acs.orglett.9b04665. Epub 2020 Jan 23.


Body mass index and albumin levels are prognostic factors for long-term survival in elders with limited performance status.

Lai KY, Wu TH, Liu CS, Lin CH, Lin CC, Lai MM, Lin WY.

Aging (Albany NY). 2020 Jan 16;12(2):1104-1113. doi: 10.18632/aging.102642. Epub 2020 Jan 16.


Fusion of augmented reality imaging with the endoscopic view for endonasal skull base surgery; a novel application for surgical navigation based on intraoperative cone beam computed tomography and optical tracking.

Lai M, Skyrman S, Shan C, Babic D, Homan R, Edström E, Persson O, Burström G, Elmi-Terander A, Hendriks BHW, de With PHN.

PLoS One. 2020 Jan 16;15(1):e0227312. doi: 10.1371/journal.pone.0227312. eCollection 2020. Erratum in: PLoS One. 2020 Feb 13;15(2):e0229454.


Histone 3 lysine 9 acetylation of BRG1 in the medial prefrontal cortex is associated with heroin self‑administration in rats.

Hong Q, Liu J, Lin Z, Zhuang D, Xu W, Xu Z, Lai M, Zhu H, Zhou W, Liu H.

Mol Med Rep. 2020 Jan;21(1):405-412. doi: 10.3892/mmr.2019.10845. Epub 2019 Nov 22.


High Dietary Intake of Vegetable or Polyunsaturated Fats is Associated With Reduced Risk of Hepatocellular Carcinoma.

Yang W, Sui J, Ma Y, Simon TG, Petrick JL, Lai M, McGlynn KA, Campbell PT, Giovannucci EL, Chan AT, Zhang X.

Clin Gastroenterol Hepatol. 2020 Jan 9. pii: S1542-3565(20)30035-5. doi: 10.1016/j.cgh.2020.01.003. [Epub ahead of print]


Perceptions of artificial intelligence in healthcare: findings from a qualitative survey study among actors in France.

Laï MC, Brian M, Mamzer MF.

J Transl Med. 2020 Jan 9;18(1):14. doi: 10.1186/s12967-019-02204-y.


Translation control of Enterovirus A71 gene expression.

Lai MC, Chen HH, Xu P, Wang RYL.

J Biomed Sci. 2020 Jan 8;27(1):22. doi: 10.1186/s12929-019-0607-9. Review.


T2 Fluid-Attenuated Inversion Recovery Resection for Glioblastoma Involving Eloquent Brain Areas Facilitated Through Awake Craniotomy and Clinical Outcome.

Lu M, Fu ZH, He XJ, Lu JK, Deng XQ, Lin DL, Gu YM, Fan YF, Lai MY, Li J, Yang MM, Chen ZP.

World Neurosurg. 2019 Dec 30. pii: S1878-8750(19)33162-6. doi: 10.1016/j.wneu.2019.12.130. [Epub ahead of print]


O-GlcNAcylation as a Therapeutic Target for Alzheimer's Disease.

Park J, Lai MKP, Arumugam TV, Jo DG.

Neuromolecular Med. 2020 Jan 1. doi: 10.1007/s12017-019-08584-0. [Epub ahead of print] Review.


Characterization of the Inhibitory Effect of Gastrodigenin and Gastrodin on M-type K+ Currents in Pituitary Cells and Hippocampal Neurons.

Yang CS, Lai MC, Liu PY, Lo YC, Huang CW, Wu SN.

Int J Mol Sci. 2019 Dec 23;21(1). pii: E117. doi: 10.3390/ijms21010117.


Ultra-smooth TiO2 thin film based optical humidity sensor with a fast response and recovery.

Wang X, Lai M, Gao R, Huang X, Zhao Z, Yang Y, Zheng G, Ma Y.

Appl Opt. 2019 Dec 20;58(36):9740-9745. doi: 10.1364/AO.58.009740.


[Morphological characteristics identification and molecular DNA barcoding analysis of Hippocampus spinosissimus].

Sun SY, Fang Y, Lai MR, Ge YQ, Zhang GJ, Cheng RB.

Zhongguo Zhong Yao Za Zhi. 2019 Nov;44(22):4837-4843. doi: 10.19540/j.cnki.cjcmm.20190829.109. Chinese.


Pulmonary Function and CT Scan Imaging at Low-Level Occupational Exposureto Asbestos.

Satta G, Serra T, Meloni F, Lazzarato A, Argiolas A, Bosu E, Coratza A, Frau N, Lai M, Lecca LI, Mascia N, Pilia I, Piras V, Sferlazzo G, Campagna M, Cocco P.

Int J Environ Res Public Health. 2019 Dec 19;17(1). pii: E50. doi: 10.3390/ijerph17010050.


Thiol-Reactive Star Polymers Functionalized with Short Ethoxy-Containing Moieties Exhibit Enhanced Uptake in Acute Lymphoblastic Leukemia Cells.

Bayat N, McOrist N, Ariotti N, Lai M, Sia KC, Li Y, Grace JL, Quinn JF, Whittaker MR, Kavallaris M, Davis TP, Lock RB.

Int J Nanomedicine. 2019 Dec 11;14:9795-9808. doi: 10.2147/IJN.S220326. eCollection 2019.


Effects of Single Nucleotide Polymorphisms in Human KCNMA1 on BK Current Properties.

Plante AE, Lai MH, Lu J, Meredith AL.

Front Mol Neurosci. 2019 Dec 3;12:285. doi: 10.3389/fnmol.2019.00285. eCollection 2019.


Protective effects of 10,11-dihydro-5H-dibenzo[b,f]azepine hydroxamates on vascular cognitive impairment.

Kaur N, Fang YC, Lee HY, Singh A, Nepali K, Lin MH, Yeh TK, Lai MJ, Chan L, Tu YK, Banerjee S, Hu CJ, Liou JP.

Eur J Med Chem. 2020 Feb 1;187:111915. doi: 10.1016/j.ejmech.2019.111915. Epub 2019 Nov 26.


Implications of gut microbiota dysbiosis and metabolic changes in prion disease.

Yang D, Zhao D, Shah SZA, Wu W, Lai M, Zhang X, Li J, Guan Z, Zhao H, Li W, Gao H, Zhou X, Yang L.

Neurobiol Dis. 2020 Feb;135:104704. doi: 10.1016/j.nbd.2019.104704. Epub 2019 Dec 16.


Genome-wide methylation and expression profiling identify methylation-associated genes in colorectal cancer.

Sun X, Chen D, Jin Z, Chen T, Lin A, Jin H, Zhu Y, Lai M.

Epigenomics. 2020 Jan;12(1):19-36. doi: 10.2217/epi-2019-0133. Epub 2019 Dec 13.


GLTSCR1 Negatively Regulates BRD4-Dependent Transcription Elongation and Inhibits CRC Metastasis.

Han F, Zhang L, Chen C, Wang Y, Zhang Y, Qian L, Sun W, Zhou D, Yang B, Zhang H, Lai M.

Adv Sci (Weinh). 2019 Oct 16;6(23):1901114. doi: 10.1002/advs.201901114. eCollection 2019 Dec.


Review of Clinical Studies Targeting Inflammatory Pathways for Individuals With Autism.

Hafizi S, Tabatabaei D, Lai MC.

Front Psychiatry. 2019 Nov 25;10:849. doi: 10.3389/fpsyt.2019.00849. eCollection 2019. Review.


Medication-rights detection using incident reports: A natural language processing and deep neural network approach.

Wong ZS, So HY, Kwok BS, Lai MW, Sun DT.

Health Informatics J. 2019 Dec 10:1460458219889798. doi: 10.1177/1460458219889798. [Epub ahead of print]


Sex and gender impacts on the behavioural presentation and recognition of autism.

Lai MC, Szatmari P.

Curr Opin Psychiatry. 2020 Mar;33(2):117-123. doi: 10.1097/YCO.0000000000000575.


KYA1797K down-regulates PD-L1 in colon cancer stem cells to block immune evasion by suppressing the β-catenin/STT3 signaling pathway.

Ruan Z, Liang M, Lai M, Shang L, Deng X, Su X.

Int Immunopharmacol. 2020 Jan;78:106003. doi: 10.1016/j.intimp.2019.106003. Epub 2019 Dec 5.


Additively protective effects of vitamin D and calcium against colorectal adenoma incidence, malignant transformation and progression: A systematic review and meta-analysis.

Huang D, Lei S, Wu Y, Weng M, Zhou Y, Xu J, Xia D, Xu E, Lai M, Zhang H.

Clin Nutr. 2019 Nov 16. pii: S0261-5614(19)33139-5. doi: 10.1016/j.clnu.2019.11.012. [Epub ahead of print]


The Role of the Gut Microbiota in the Pathogenesis of Parkinson's Disease.

Yang D, Zhao D, Ali Shah SZ, Wu W, Lai M, Zhang X, Li J, Guan Z, Zhao H, Li W, Gao H, Zhou X, Yang L.

Front Neurol. 2019 Nov 6;10:1155. doi: 10.3389/fneur.2019.01155. eCollection 2019. Review.


Bottom-up structural proteomics: cryoEM of protein complexes enriched from the cellular milieu.

Ho CM, Li X, Lai M, Terwilliger TC, Beck JR, Wohlschlegel J, Goldberg DE, Fitzpatrick AWP, Zhou ZH.

Nat Methods. 2020 Jan;17(1):79-85. doi: 10.1038/s41592-019-0637-y. Epub 2019 Nov 25.


Galectin-1 attenuates hepatic ischemia reperfusion injury in mice.

Ye Y, Wang W, Zhang W, Peng Y, Liu Y, Yu S, Chen Q, Geng L, Zhou L, Xie H, Lai M, Yu J, Zheng S.

Int Immunopharmacol. 2019 Dec;77:105997. doi: 10.1016/j.intimp.2019.105997. Epub 2019 Nov 21.


Genome-wide association mapping of gene loci affecting disease resistance in the rice-Fusarium fujikuroi pathosystem.

Chen SY, Lai MH, Tung CW, Wu DH, Chang FY, Lin TC, Chung CL.

Rice (N Y). 2019 Nov 21;12(1):85. doi: 10.1186/s12284-019-0337-3.


Genetic polymorphisms of 19 autosomal STR loci in 3510 individuals from Han population of Zhejiang province, Southeast China.

Wang Y, Chen F, Fu Y, Zhang S, Zhang H, Lai M, Xu E.

Forensic Sci Int. 2020 Jan;306:110045. doi: 10.1016/j.forsciint.2019.110045. Epub 2019 Nov 6. No abstract available.


Including Fibroblast Growth Factor-21 in Combined Biomarker Panels Improves Predictions of Liver Steatosis Severity in Children.

Hua MC, Huang JL, Hu CC, Yao TC, Lai MW.

Front Pediatr. 2019 Oct 30;7:420. doi: 10.3389/fped.2019.00420. eCollection 2019.


Correction: A novel derivative of betulinic acid, SYK023, suppresses lung cancer growth and malignancy.

Hsu TI, Chen YJ, Hung CY, Wang YC, Lin SJ, Su WC, Lai MD, Kim SY, Wang Q, Qian K, Goto M, Zhao Y, Kashiwada Y, Lee KH, Chang WC, Hung JJ.

Oncotarget. 2019 Nov 5;10(60):6536-6537. doi: 10.18632/oncotarget.27297. eCollection 2019 Nov 5.


Doravirine versus ritonavir-boosted darunavir in antiretroviral-naive adults with HIV-1 (DRIVE-FORWARD): 96-week results of a randomised, double-blind, non-inferiority, phase 3 trial.

Molina JM, Squires K, Sax PE, Cahn P, Lombaard J, DeJesus E, Lai MT, Rodgers A, Lupinacci L, Kumar S, Sklar P, Hanna GJ, Hwang C, Martin EA; DRIVE-FORWARD trial group.

Lancet HIV. 2020 Jan;7(1):e16-e26. doi: 10.1016/S2352-3018(19)30336-4. Epub 2019 Nov 15.


Remifentanil-Induced Transient Right Bundle Branch Block During Hemorrhoidectomy

Lin YC, Lai MF, Lai HC, Wu ZF.

Asian J Anesthesiol. 2019 Dec 1;57(4):128-129. doi: 10.6859/aja.201912_57(4).0004. Epub 2019 Nov 6. No abstract available.


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