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Trans-omics biomarker model improves prognostic prediction accuracy for early-stage lung adenocarcinoma.

Dong X, Zhang R, He J, Lai L, Alolga RN, Shen S, Zhu Y, You D, Lin L, Chen C, Zhao Y, Duan W, Su L, Shafer A, Salama M, Fleischer T, Bjaanæs MM, Karlsson A, Planck M, Wang R, Staaf J, Helland Å, Esteller M, Wei Y, Chen F, Christiani DC.

Aging (Albany NY). 2019 Aug 21;11. doi: 10.18632/aging.102189. [Epub ahead of print]


Corrigendum to "Genome-Wide RNAi Screen Identify Melanoma-Associated Antigen Mageb3 Involved in X Chromosome Inactivation" [J. Mol. Biol. 430 (2018) 2734-2746].

Li W, Hong R, Lai LT, Dong Q, Ni P, Chelliah R, Huq M, Ismail SNB, Chandola U, Ang Z, Lin B, Chen X, Chen L, Zhang LF.

J Mol Biol. 2019 Aug 12. pii: S0022-2836(19)30483-8. doi: 10.1016/j.jmb.2019.07.032. [Epub ahead of print] No abstract available.


Identification of SWI2/SNF2-Related 1 Chromatin Remodeling Complex (SWR1-C) Subunits in Pineapple and the Role of Pineapple SWR1 COMPLEX 6 (AcSWC6) in Biotic and Abiotic Stress Response.

Jakada BH, Aslam M, Fakher B, Greaves JG, Li Z, Li W, Lai L, Ayoade OA, Cheng Y, Cao S, Li G, Hu JM, Qin Y.

Biomolecules. 2019 Aug 13;9(8). pii: E364. doi: 10.3390/biom9080364.


Using proteomic profiling to characterize protein signatures of different thymoma subtypes.

Lai LC, Sun QL, Chen YA, Hsiao YW, Lu TP, Tsai MH, Zhu L, Chuang EY, Fang W.

BMC Cancer. 2019 Aug 13;19(1):796. doi: 10.1186/s12885-019-6023-4.


Sex-limited penetrance of lymphedema to females with CELSR1 haploinsufficiency: A second family.

Erickson RP, Lai LW, Mustacich DJ, Bernas MJ, Kuo PH, Witte MH.

Clin Genet. 2019 Aug 12. doi: 10.1111/cge.13622. [Epub ahead of print]


Comparison of early postoperative results between robot-assisted and laparoscopic splenectomy for non-traumatic splenic diseases rather than portal hypertensive hypersplenism-a meta-analysis.

Peng F, Lai L, Luo M, Su S, Zhang M, He K, Xia X, He P.

Asian J Surg. 2019 Jul 23. pii: S1015-9584(19)30371-9. doi: 10.1016/j.asjsur.2019.07.010. [Epub ahead of print] Review.


Hearing Improvement Following Middle Cranial Fossa Floor Defect Repair Utilizing a Modified Middle Fossa Approach and Reconstructive Techniques.

Alwan M, Ibbett I, Pullar M, Lai LT, Gordon M.

Otol Neurotol. 2019 Sep;40(8):1034-1039. doi: 10.1097/MAO.0000000000002322.


[Chemical constituents from fruiting bodies of Tremella sanguinea].

Yang S, Gao YQ, Zhang MM, Lai L, Liu YP, Bao HY, Fu YH.

Zhongguo Zhong Yao Za Zhi. 2019 May;44(9):1836-1841. doi: 10.19540/j.cnki.cjcmm.20190222.005. Chinese.


Anesthesiologists' acquisition of hepatitis B virus infection: Risk and prevention.

Tian J, Tan F, Lai L, Deng Y, Chi X, Geng H, Zhu Q.

Medicine (Baltimore). 2019 Jul;98(29):e16416. doi: 10.1097/MD.0000000000016416.


VariED: the first integrated database of gene annotation and expression profiles for variants related to human diseases.

Lee CY, Chattopadhyay A, Chiang LM, Juang JJ, Lai LC, Tsai MH, Lu TP, Chuang EY.

Database (Oxford). 2019 Jan 1;2019. pii: baz075. doi: 10.1093/database/baz075.


miR-15b induces premature ovarian failure in mice via inhibition of α-Klotho expression in ovarian granulosa cells.

Liu T, Liu Y, Huang Y, Chen J, Yu Z, Chen C, Lai L.

Free Radic Biol Med. 2019 Jul 13;141:383-392. doi: 10.1016/j.freeradbiomed.2019.07.010. [Epub ahead of print]


Comparing point shear wave elastography (ElastPQ) and transient elastography for diagnosis of fibrosis stage in non-alcoholic fatty liver disease.

Leong WL, Lai LL, Nik Mustapha NR, Vijayananthan A, Rahmat K, Mahadeva S, Chan WK.

J Gastroenterol Hepatol. 2019 Jul 16. doi: 10.1111/jgh.14782. [Epub ahead of print]


Subnanometer resolution cryo-EM structure of Arabidopsis thaliana ATG9.

Lai LTF, Yu C, Wong JSK, Lo HS, Benlekbir S, Jiang L, Lau WCY.

Autophagy. 2019 Jul 16:1-9. doi: 10.1080/15548627.2019.1639300. [Epub ahead of print]


Improving knowledge of doctors and paramedics through effective bone procurement workshop: A cognitive approach.

Mohd S, Yusof N, Lai LL, Hossain MG, Ramalingam S, Hamid SSA, Ng WM, Mansor A.

BMC Med Educ. 2019 Jul 1;19(1):238. doi: 10.1186/s12909-019-1685-9.


The role and mechanism of microRNA‑18a‑5p in oral squamous cell carcinoma.

Huang C, Song H, Lai L.

Mol Med Rep. 2019 Aug;20(2):1637-1644. doi: 10.3892/mmr.2019.10403. Epub 2019 Jun 20.


Efficient base editing for multiple genes and loci in pigs using base editors.

Xie J, Ge W, Li N, Liu Q, Chen F, Yang X, Huang X, Ouyang Z, Zhang Q, Zhao Y, Liu Z, Gou S, Wu H, Lai C, Fan N, Jin Q, Shi H, Liang Y, Lan T, Quan L, Li X, Wang K, Lai L.

Nat Commun. 2019 Jun 28;10(1):2852. doi: 10.1038/s41467-019-10421-8.


Synthesis of Mesoporous TiO2-B Nanobelts with Highly Crystalized Walls toward Efficient H2 Evolution.

Li P, Cao Q, Zheng D, Alshehri AA, Alghamidi YG, Alzahrani KA, Kim M, Hou J, Lai L, Yamauchi Y, Ide Y, Bando Y, Kim J, Malgras V, Lin J.

Nanomaterials (Basel). 2019 Jun 26;9(7). pii: E919. doi: 10.3390/nano9070919.


Fbxw7 increases CCL2/7 in CX3CR1hi macrophages to promote intestinal inflammation.

He J, Song Y, Li G, Xiao P, Liu Y, Xue Y, Cao Q, Tu X, Pan T, Jiang Z, Cao X, Lai L, Wang Q.

J Clin Invest. 2019 Jun 27;130. pii: 123374. doi: 10.1172/JCI123374.


Efficient and precise base editing in rabbits using human APOBEC3A-nCas9 fusions.

Liu Z, Chen S, Shan H, Zhang Q, Chen M, Lai L, Li Z.

Cell Discov. 2019 Jun 11;5:31. doi: 10.1038/s41421-019-0099-5. eCollection 2019. No abstract available.


Golgi phosphoprotein-3 promotes invasiveness of gastric cancer cells through the mTOR signalling pathway.

Liu J, Wei H, Lai L, Wang Y, Han X, Zhang Z.

Clin Invest Med. 2019 Jun 23;42(2):E38-47. doi: 10.25011/cim.v42i2.32815.


Comparative studies on the surface/interface properties and aggregation behavior of mono-rhamnolipid and di-rhamnolipid.

Wu LM, Lai L, Lu Q, Mei P, Wang YQ, Cheng L, Liu Y.

Colloids Surf B Biointerfaces. 2019 Sep 1;181:593-601. doi: 10.1016/j.colsurfb.2019.06.012. Epub 2019 Jun 7.


Skint8, a Novel B7 Family-Related Molecule, Negatively Regulates T Cell Responses.

Lin Y, Cui C, Su M, Tian X, Huang Y, Zhao J, Lai L.

J Immunol. 2019 Jul 15;203(2):400-407. doi: 10.4049/jimmunol.1800639. Epub 2019 Jun 12.


Amyloid β precursor protein silencing attenuates epithelial‑mesenchymal transition of nasopharyngeal carcinoma cells via inhibition of the MAPK pathway.

Xu J, Ying Y, Xiong G, Lai L, Wang Q, Yang Y.

Mol Med Rep. 2019 Jul;20(1):409-416. doi: 10.3892/mmr.2019.10293. Epub 2019 May 24.


[The role of lysosomes in manganese-induced toxicity in SK-N-SH cells].

Zhi CN, Lai LL, Dou CS, Wang XH, Zhao P, Fu JL, Yao BY.

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 2019 May 20;37(5):332-336. doi: 10.3760/cma.j.issn.1001-9391.2019.05.003. Chinese.


SIRT1 protects cochlear hair cell and delays age-related hearing loss via autophagy.

Pang J, Xiong H, Ou Y, Yang H, Xu Y, Chen S, Lai L, Ye Y, Su Z, Lin H, Huang Q, Xu X, Zheng Y.

Neurobiol Aging. 2019 Aug;80:127-137. doi: 10.1016/j.neurobiolaging.2019.04.003. Epub 2019 Apr 15.


Author Correction: Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC.

Nat Commun. 2019 Jun 4;10(1):2530. doi: 10.1038/s41467-019-10536-y.


Establishment of porcine and human expanded potential stem cells.

Gao X, Nowak-Imialek M, Chen X, Chen D, Herrmann D, Ruan D, Chen ACH, Eckersley-Maslin MA, Ahmad S, Lee YL, Kobayashi T, Ryan D, Zhong J, Zhu J, Wu J, Lan G, Petkov S, Yang J, Antunes L, Campos LS, Fu B, Wang S, Yong Y, Wang X, Xue SG, Ge L, Liu Z, Huang Y, Nie T, Li P, Wu D, Pei D, Zhang Y, Lu L, Yang F, Kimber SJ, Reik W, Zou X, Shang Z, Lai L, Surani A, Tam PPL, Ahmed A, Yeung WSB, Teichmann SA, Niemann H, Liu P.

Nat Cell Biol. 2019 Jun;21(6):687-699. doi: 10.1038/s41556-019-0333-2. Epub 2019 Jun 3.


Mutations of GADD45G in rabbits cause cleft lip by the disorder of proliferation, apoptosis and epithelial-mesenchymal transition (EMT).

Lu Y, Liang M, Zhang Q, Liu Z, Song Y, Lai L, Li Z.

Biochim Biophys Acta Mol Basis Dis. 2019 Sep 1;1865(9):2356-2367. doi: 10.1016/j.bbadis.2019.05.015. Epub 2019 May 29.


Preparation of AgCl/TNTs nanocomposites for organic dyes and inorganic heavy metal removal.

Tsai CY, Liu CW, Hsi HC, Lin KS, Lin YW, Lai LC, Weng TN.

Environ Sci Pollut Res Int. 2019 Jul;26(21):22082-22096. doi: 10.1007/s11356-019-05570-8. Epub 2019 May 30.


Glioblastoma presenting as spontaneous subarachnoid hemorrhage: a technical case note of combined endovascular and microsurgical vision sparing treatment.

Tan D, Daly C, Xenos C, Lai LT, Chandra RV.

World Neurosurg. 2019 May 20. pii: S1878-8750(19)31364-6. doi: 10.1016/j.wneu.2019.05.090. [Epub ahead of print]


Interaction Mechanism of Different Surfactants with Casein: A Perspective on Bulk and Interfacial Phase Behavior.

Tian Q, Lai L, Zhou Z, Mei P, Lu Q, Wang Y, Xiang D, Liu Y.

J Agric Food Chem. 2019 Jun 5;67(22):6336-6349. doi: 10.1021/acs.jafc.9b00969. Epub 2019 May 28.


Primary intradural extramedullary Ewing sarcoma of the cervical spine: A case report and review of the literature.

Tan CH, Tan D, Phung TB, Lai LT.

J Clin Neurosci. 2019 Aug;66:280-284. doi: 10.1016/j.jocn.2019.05.005. Epub 2019 May 18.


An Overview of the Randomized Placebo-Controlled Trials of Chinese Herbal Medicine Formula Granules.

Han M, Lai L, Li XX, Zhao NQ, Li J, Xia Y, Liu JP.

Evid Based Complement Alternat Med. 2019 Apr 11;2019:6486293. doi: 10.1155/2019/6486293. eCollection 2019. Review.


Computational design and optimization of novel d-peptide TNFα inhibitors.

Yang W, Zhang Q, Zhang C, Guo A, Wang Y, You H, Zhang X, Lai L.

FEBS Lett. 2019 Jun;593(12):1292-1302. doi: 10.1002/1873-3468.13444. Epub 2019 May 29.


Differentiating the Effects of Oxidative Stress Tests on Biopharmaceuticals.

Heinzl GA, Lai L, Rao VA.

Pharm Res. 2019 May 17;36(7):103. doi: 10.1007/s11095-019-2627-2.


Toward a comprehensive explanatory model of reliance on alternatives to the tap: evidence from California's retail water stores.

Pierce G, Lai L.

J Water Health. 2019 Jun;17(3):455-462. doi: 10.2166/wh.2019.289.


anamiR: integrated analysis of MicroRNA and gene expression profiling.

Wang TT, Lee CY, Lai LC, Tsai MH, Lu TP, Chuang EY.

BMC Bioinformatics. 2019 May 14;20(1):239. doi: 10.1186/s12859-019-2870-x.


Investigating targets for neuropharmacological intervention by molecular dynamics simulations.

Rossetti G, Kless A, Lai L, Outeiro TF, Carloni P.

Biochem Soc Trans. 2019 Jun 28;47(3):909-918. doi: 10.1042/BST20190048. Epub 2019 May 13. Review.


Improved base editor for efficient editing in GC contexts in rabbits with an optimized AID-Cas9 fusion.

Liu Z, Shan H, Chen S, Chen M, Zhang Q, Lai L, Li Z.

FASEB J. 2019 Aug;33(8):9210-9219. doi: 10.1096/fj.201900476RR. Epub 2019 May 9.


Comparative proteomic analysis of human serum before and after liver transplantation using quantitative proteomics.

Zhang R, Ou M, Zhang Y, Yan Q, Chen H, Lai L, Li Y, Xu F, Tang D, Sun X, Dong J, Dai Y, Sui W.

Oncotarget. 2019 Apr 2;10(26):2508-2514. doi: 10.18632/oncotarget.26761. eCollection 2019 Apr 2.


The effect and molecular mechanism of statins on the expression of human anti-coagulation genes.

Chang SN, Wu CK, Lai LP, Chiang FT, Hwang JJ, Tsai CT.

Cell Mol Life Sci. 2019 May 3. doi: 10.1007/s00018-019-03100-w. [Epub ahead of print]


miR-206 inhibits cell proliferation, invasion, and migration by down-regulating PTP1B in hepatocellular carcinoma.

Yang Q, Zhang L, Zhong Y, Lai L, Li X.

Biosci Rep. 2019 May 15;39(5). pii: BSR20181823. doi: 10.1042/BSR20181823. Print 2019 May 31.


Interstitial Pulmonary Edema Assessed by Lung Ultrasound on Ascent to High Altitude and Slight Association with Acute Mountain Sickness: A Prospective Observational Study.

Alsup C, Lipman GS, Pomeranz D, Huang RW, Burns P, Juul N, Phillips C, Jurkiewicz C, Cheffers M, Evans K, Saraswathula A, Baumeister P, Lai L, Rainey J, Lobo V.

High Alt Med Biol. 2019 Jun;20(2):150-156. doi: 10.1089/ham.2018.0123. Epub 2019 May 7.


Expanded targeting scope and enhanced base editing efficiency in rabbit using optimized xCas9(3.7).

Liu Z, Chen M, Shan H, Chen S, Xu Y, Song Y, Zhang Q, Yuan H, Ouyang H, Li Z, Lai L.

Cell Mol Life Sci. 2019 Apr 27. doi: 10.1007/s00018-019-03110-8. [Epub ahead of print]


[Clinical outcomes of open reduction and internal fixation in treating Gustilo typeI and II patients with open distal humeral fractures].

Chen C, Zha YJ, Li T, Jiang XY, Lai LP, Gong MQ.

Zhongguo Gu Shang. 2019 Apr 25;32(4):350-354. doi: 10.3969/j.issn.1003-0034.2019.04.011. Chinese.


Modulation of miR-34a/SIRT1 signaling protects cochlear hair cells against oxidative stress and delays age-related hearing loss through coordinated regulation of mitophagy and mitochondrial biogenesis.

Xiong H, Chen S, Lai L, Yang H, Xu Y, Pang J, Su Z, Lin H, Zheng Y.

Neurobiol Aging. 2019 Jul;79:30-42. doi: 10.1016/j.neurobiolaging.2019.03.013. Epub 2019 Mar 27.


Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing.

Siddiqi FH, Menzies FM, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, Ricketts T, Jimenez-Sanchez M, Esteban MA, Lai L, Tortorella MD, Luo Z, Liu H, Metzakopian E, Fernandes HJR, Bassett A, Karran E, Miller BL, Fleming A, Rubinsztein DC.

Nat Commun. 2019 Apr 18;10(1):1817. doi: 10.1038/s41467-019-09494-2. Erratum in: Nat Commun. 2019 Jun 4;10(1):2530.


Self-Assembly of Copper Polypyridyl Supramolecular Metallopolymers to Achieve Enhanced Anticancer Efficacy.

Lai L, Luo D, Liu T, Zheng W, Chen T, Li D.

ChemistryOpen. 2019 Apr 2;8(4):434-437. doi: 10.1002/open.201900036. eCollection 2019 Apr.

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