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Items: 1 to 50 of 177

1.

Role of Mesangial-Podocytic-Tubular Cross-Talk in IgA Nephropathy.

Leung JCK, Lai KN, Tang SCW.

Semin Nephrol. 2018 Sep;38(5):485-495. doi: 10.1016/j.semnephrol.2018.05.018. Review.

PMID:
30177020
2.

Activated renal tubular Wnt/β-catenin signaling triggers renal inflammation during overload proteinuria.

Wong DWL, Yiu WH, Chan KW, Li Y, Li B, Lok SWY, Taketo MM, Igarashi P, Chan LYY, Leung JCK, Lai KN, Tang SCW.

Kidney Int. 2018 Jun;93(6):1367-1383. doi: 10.1016/j.kint.2017.12.017. Epub 2018 Mar 28.

PMID:
29605095
3.

Complement C5a inhibition moderates lipid metabolism and reduces tubulointerstitial fibrosis in diabetic nephropathy.

Yiu WH, Li RX, Wong DWL, Wu HJ, Chan KW, Chan LYY, Leung JCK, Lai KN, Sacks SH, Zhou W, Tang SCW.

Nephrol Dial Transplant. 2017 Dec 26. doi: 10.1093/ndt/gfx336. [Epub ahead of print]

PMID:
29294056
4.

Human induced pluripotent stem cell-derived mesenchymal stem cells prevent adriamycin nephropathy in mice.

Wu HJ, Yiu WH, Wong DWL, Li RX, Chan LYY, Leung JCK, Zhang Y, Lian Q, Lai KN, Tse HF, Tang SCW.

Oncotarget. 2017 Oct 10;8(61):103640-103656. doi: 10.18632/oncotarget.21760. eCollection 2017 Nov 28.

5.

N-acetyl-seryl-aspartyl-lysyl-proline mediates the anti-fibrotic properties of captopril in unilateral ureteric obstructed BALB/C mice.

Chan GCW, Wu HJ, Chan KW, Yiu WH, Zou A, Huang XR, Lan HY, Lai KN, Tang SCW.

Nephrology (Carlton). 2018 Apr;23(4):297-307. doi: 10.1111/nep.13000.

PMID:
28075040
6.

Semi-individualised Chinese medicine treatment as an adjuvant management for diabetic nephropathy: a pilot add-on, randomised, controlled, multicentre, open-label pragmatic clinical trial.

Chan KW, Ip TP, Kwong AS, Lui SL, Chan GC, Cowling BJ, Yiu WH, Wong DW, Liu Y, Feng Y, Tan KC, Chan LY, Leung JC, Lai KN, Tang SC.

BMJ Open. 2016 Aug 5;6(8):e010741. doi: 10.1136/bmjopen-2015-010741.

7.

Recent advances in managing and understanding diabetic nephropathy.

Tang SC, Chan GC, Lai KN.

F1000Res. 2016 May 31;5. pii: F1000 Faculty Rev-1044. doi: 10.12688/f1000research.7693.1. eCollection 2016. Review.

8.

IgA nephropathy.

Lai KN, Tang SC, Schena FP, Novak J, Tomino Y, Fogo AB, Glassock RJ.

Nat Rev Dis Primers. 2016 Feb 11;2:16001. doi: 10.1038/nrdp.2016.1. Review.

PMID:
27189177
9.

Recent advances in the understanding and management of IgA nephropathy.

Lai KN, Leung JC, Tang SC.

F1000Res. 2016 Feb 11;5. pii: F1000 Faculty Rev-161. doi: 10.12688/f1000research.7352.1. eCollection 2016. Review.

10.

Kallistatin protects against diabetic nephropathy in db/db mice by suppressing AGE-RAGE-induced oxidative stress.

Yiu WH, Wong DW, Wu HJ, Li RX, Yam I, Chan LY, Leung JC, Lan HY, Lai KN, Tang SC.

Kidney Int. 2016 Feb;89(2):386-98.

PMID:
26536000
11.

Proteinuria is associated with sleep apnea in chronic kidney disease.

Chan GC, Lam B, Yap DY, Ip MS, Lai KN, Tang SC.

Nephrol Dial Transplant. 2016 May;31(5):772-9. doi: 10.1093/ndt/gfv306. Epub 2015 Aug 26.

PMID:
26311214
12.

The Treatment of IgA Nephropathy.

Lai KN, Leung JC, Tang SC.

Kidney Dis (Basel). 2015 May;1(1):19-26. doi: 10.1159/000381508. Epub 2015 Apr 15. Review.

13.

Combined blockade of angiotensin II and prorenin receptors ameliorates podocytic apoptosis induced by IgA-activated mesangial cells.

Leung JC, Chan LY, Saleem MA, Mathieson PW, Tang SC, Lai KN.

Apoptosis. 2015 Jul;20(7):907-20. doi: 10.1007/s10495-015-1117-1.

PMID:
25808596
14.

Diabetic nephropathy and proximal tubular damage.

Tang SC, Yiu WH, Lin M, Lai KN.

J Ren Nutr. 2015 Mar;25(2):230-3. doi: 10.1053/j.jrn.2014.10.020. Epub 2015 Jan 8. Review.

PMID:
25578352
15.

BMP7 reduces inflammation and oxidative stress in diabetic tubulopathy.

Li RX, Yiu WH, Wu HJ, Wong DW, Chan LY, Lin M, Leung JC, Lai KN, Tang SC.

Clin Sci (Lond). 2015 Feb;128(4):269-80. doi: 10.1042/CS20140401.

PMID:
25200314
16.

Albumin and glycated albumin activate KIM-1 release in tubular epithelial cells through distinct kinetics and mechanisms.

Lim AI, Chan LY, Tang SC, Lai KN, Leung JC.

Inflamm Res. 2014 Oct;63(10):831-9. doi: 10.1007/s00011-014-0757-x. Epub 2014 Jul 26.

PMID:
25063374
17.

Mesenchymal stem cells modulate albumin-induced renal tubular inflammation and fibrosis.

Wu HJ, Yiu WH, Li RX, Wong DW, Leung JC, Chan LY, Zhang Y, Lian Q, Lin M, Tse HF, Lai KN, Tang SC.

PLoS One. 2014 Mar 19;9(3):e90883. doi: 10.1371/journal.pone.0090883. eCollection 2014.

18.

Tissue kallikrein mediates pro-inflammatory pathways and activation of protease-activated receptor-4 in proximal tubular epithelial cells.

Yiu WH, Wong DW, Chan LY, Leung JC, Chan KW, Lan HY, Lai KN, Tang SC.

PLoS One. 2014 Feb 21;9(2):e88894. doi: 10.1371/journal.pone.0088894. eCollection 2014.

19.

BMP-7 represses albumin-induced chemokine synthesis in kidney tubular epithelial cells through destabilization of NF-κB-inducing kinase.

Lim AI, Chan LY, Tang SC, Yiu WH, Li R, Lai KN, Leung JC.

Immunol Cell Biol. 2014 May-Jun;92(5):427-35. doi: 10.1038/icb.2013.106. Epub 2014 Jan 14.

PMID:
24418819
20.

Effect of paricalcitol on left ventricular mass and function in CKD--the OPERA trial.

Wang AY, Fang F, Chan J, Wen YY, Qing S, Chan IH, Lo G, Lai KN, Lo WK, Lam CW, Yu CM.

J Am Soc Nephrol. 2014 Jan;25(1):175-86. doi: 10.1681/ASN.2013010103. Epub 2013 Sep 19.

21.

Hepatitis C virus-associated glomerulonephritis.

Tang SC, Lai KN.

Contrib Nephrol. 2013;181:194-206. doi: 10.1159/000348477. Epub 2013 May 8. Review.

PMID:
23689581
22.

The role of cytokines in the pathogenesis of systemic lupus erythematosus - from bench to bedside.

Yap DY, Lai KN.

Nephrology (Carlton). 2013 Apr;18(4):243-55. doi: 10.1111/nep.12047. Review.

PMID:
23452295
23.

The TLR4 antagonist CRX-526 protects against advanced diabetic nephropathy.

Lin M, Yiu WH, Li RX, Wu HJ, Wong DW, Chan LY, Leung JC, Lai KN, Tang SC.

Kidney Int. 2013 May;83(5):887-900. doi: 10.1038/ki.2013.11. Epub 2013 Feb 20.

24.

Kidney injury molecule-1: more than just an injury marker of tubular epithelial cells?

Lim AI, Tang SC, Lai KN, Leung JC.

J Cell Physiol. 2013 May;228(5):917-24. doi: 10.1002/jcp.24267. Review.

PMID:
23086807
25.

The pathogenic role of the renal proximal tubular cell in diabetic nephropathy.

Tang SC, Lai KN.

Nephrol Dial Transplant. 2012 Aug;27(8):3049-56. doi: 10.1093/ndt/gfs260. Epub 2012 Jun 25. Review.

PMID:
22734110
26.

Distinct role of matrix metalloproteinase-3 in kidney injury molecule-1 shedding by kidney proximal tubular epithelial cells.

Lim AI, Chan LY, Lai KN, Tang SC, Chow CW, Lam MF, Leung JC.

Int J Biochem Cell Biol. 2012 Jun;44(6):1040-50. doi: 10.1016/j.biocel.2012.03.015. Epub 2012 Mar 30.

PMID:
22484054
27.

Pathogenesis of IgA nephropathy.

Lai KN.

Nat Rev Nephrol. 2012 Mar 20;8(5):275-83. doi: 10.1038/nrneph.2012.58. Review.

PMID:
22430056
28.

Quantification of BK viral load in asymptomatic renal allograft recipients.

Chan GC, Leung AY, Wong AS, Chan KW, Kwong YL, Lai KN, Tang SC.

Ren Fail. 2012;34(5):550-4. doi: 10.3109/0886022X.2012.664808. Epub 2012 Mar 6.

PMID:
22390257
29.

The role of leptin and its short-form receptor in inflammation in db/db mice infused with peritoneal dialysis fluid.

Leung JC, Chan LY, Lam MF, Tang SC, Chow CW, Lim AI, Lai KN.

Nephrol Dial Transplant. 2012 Aug;27(8):3119-29. doi: 10.1093/ndt/gfr774. Epub 2012 Jan 28.

PMID:
22287654
30.

Impact of nephrotic edema of the lower limbs on obstructive sleep apnea: gathering a unifying concept for the pathogenetic role of nocturnal rostral fluid shift.

Tang SC, Lam B, Lam JC, Chan CK, Chow CC, Ho YW, Ip MS, Lai KN.

Nephrol Dial Transplant. 2012 Jul;27(7):2788-94. doi: 10.1093/ndt/gfr759. Epub 2012 Jan 16.

PMID:
22248509
31.

A study of the clinical and biochemical profile of peritoneal dialysis fluid low in glucose degradation products.

Lai KN, Lam MF, Leung JC, Chan LY, Lam CW, Chan IH, Chan HW, Li CS, Wong SS, Ho YW, Cheuk A, Tong MK, Tang SC.

Perit Dial Int. 2012 May-Jun;32(3):280-91. doi: 10.3747/pdi.2010.00176. Epub 2011 Nov 3.

32.

Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy.

Lin M, Yiu WH, Wu HJ, Chan LY, Leung JC, Au WS, Chan KW, Lai KN, Tang SC.

J Am Soc Nephrol. 2012 Jan;23(1):86-102. doi: 10.1681/ASN.2010111210. Epub 2011 Oct 21.

33.

Oxidative damages in tubular epithelial cells in IgA nephropathy: role of crosstalk between angiotensin II and aldosterone.

Leung JC, Chan LY, Tang SC, Lam MF, Chow CW, Lim AI, Lai KN.

J Transl Med. 2011 Oct 6;9:169. doi: 10.1186/1479-5876-9-169.

34.

Immunomodulatory agents against IgA nephropathy.

Tang SC, Leung JC, Lai KN.

Adv Otorhinolaryngol. 2011;72:45-9. doi: 10.1159/000324602. Epub 2011 Aug 18. Review.

PMID:
21865687
35.

Recent advances in IgA nephropathy--the glomerulopodocytic-tubular communication.

Lai KN, Tang SC, Leung JC.

Adv Otorhinolaryngol. 2011;72:40-4. doi: 10.1159/000324593. Epub 2011 Aug 18. Review.

PMID:
21865686
36.

Clinical pictures and novel mutations of WT1-associated Denys-Drash syndrome in two Chinese children.

Yue Z, Pei Y, Sun L, Huang W, Huang H, Hu B, Yang J, Jiang X, Mo Y, Chen S, Lai KN, Wang Y.

Ren Fail. 2011;33(9):910-4. doi: 10.3109/0886022X.2011.605528. Epub 2011 Aug 18.

PMID:
21851196
37.

Streptococcus bovis peritonitis complicating peritoneal dialysis--a review of 10 years' experience.

Yap DY, To KK, Yip TP, Lui SL, Chan TM, Lai KN, Lo WK.

Perit Dial Int. 2012 Jan-Feb;32(1):55-9. doi: 10.3747/pdi.2010.00304. Epub 2011 Jul 31.

38.

Severe hypocalcaemia and hyperphosphataemia caused by oral sodium phosphate fleet solution in a haemodialysis patient after parathyroidectomy.

Mok MM, Yip T, Lui SL, Chan DT, Lai KN, Lo WK.

NDT Plus. 2011 Aug;4(4):248-50. doi: 10.1093/ndtplus/sfr070. Epub 2011 Jun 7.

39.

Aliskiren combined with losartan in immunoglobulin A nephropathy: an open-labeled pilot study.

Tang SC, Lin M, Tam S, Au WS, Ma MK, Yap DY, Ho YW, Lai KN.

Nephrol Dial Transplant. 2012 Feb;27(2):613-8. doi: 10.1093/ndt/gfr349. Epub 2011 Jun 16.

PMID:
21680850
40.

The kallikrein-kinin system.

Tang SC, Leung JC, Lai KN.

Contrib Nephrol. 2011;170:145-55. doi: 10.1159/000325650. Epub 2011 Jun 9. Review.

PMID:
21659767
41.

The renin-angiotensin system.

Lai KN, Leung JC, Tang SC.

Contrib Nephrol. 2011;170:135-44. doi: 10.1159/000325649. Epub 2011 Jun 9. Review.

PMID:
21659766
42.

Diabetic tubulopathy: an emerging entity.

Tang SC, Leung JC, Lai KN.

Contrib Nephrol. 2011;170:124-34. doi: 10.1159/000325647. Epub 2011 Jun 9. Review.

PMID:
21659765
43.

Renal cell carcinoma of native kidney in Chinese renal transplant recipients: a report of 12 cases and a review of the literature.

Cheung CY, Lam MF, Lee KC, Chan GS, Chan KW, Chau KF, Li CS, Chan TM, Lai KN.

Int Urol Nephrol. 2011 Sep;43(3):675-80. doi: 10.1007/s11255-011-9912-2. Epub 2011 Mar 10. Review.

44.

Additive renoprotective effects of B2-kinin receptor blocker and PPAR-γ agonist in uninephrectomized db/db mice.

Tang SC, Chan LY, Leung JC, Cheng AS, Lan HY, Lai KN.

Lab Invest. 2011 Sep;91(9):1351-62. doi: 10.1038/labinvest.2011.81. Epub 2011 May 2.

45.

Clinical course and outcomes of single-organism Enterococcus peritonitis in peritoneal dialysis patients.

Yip T, Tse KC, Ng F, Hung I, Lam MF, Tang S, Lui SL, Lai KN, Chan TM, Lo WK.

Perit Dial Int. 2011 Sep-Oct;31(5):522-8. doi: 10.3747/pdi.2009.00260. Epub 2011 Apr 30.

PMID:
21532006
46.

Additive effect of PPAR-γ agonist and ARB in treatment of experimental IgA nephropathy.

Lai KN, Chan LY, Guo H, Tang SC, Leung JC.

Pediatr Nephrol. 2011 Feb;26(2):257-66. doi: 10.1007/s00467-010-1703-y. Epub 2010 Dec 2.

PMID:
21125406
47.

Transhepatic placement of haemodialysis catheter: A solution for vascular access exhaustion.

Yap DY, Tso WK, Chu FS, Chan TM, Lai KN, Tang SC.

Nephrology (Carlton). 2010 Sep;15(6):661-2. No abstract available.

PMID:
20931750
48.

Renoprotection by rosiglitazone in accelerated type 2 diabetic nephropathy: Role of STAT1 inhibition and nephrin restoration.

Tang SC, Leung JC, Chan LY, Cheng AS, Lan HY, Lai KN.

Am J Nephrol. 2010;32(2):145-55. doi: 10.1159/000316056. Epub 2010 Jul 1.

PMID:
20606418
49.

Essential role for Smad3 in angiotensin II-induced tubular epithelial-mesenchymal transition.

Yang F, Huang XR, Chung AC, Hou CC, Lai KN, Lan HY.

J Pathol. 2010 Aug;221(4):390-401. doi: 10.1002/path.2721.

PMID:
20593491
50.

CT angiography versus conventional digital angiography in preoperative assessment for Chinese living kidney donors.

Yap DY, Chu FS, Chu SM, Tam PC, Tam S, Chan TM, Lai KN, Tang SC.

J Nephrol. 2010 Nov-Dec;23(6):711-6.

PMID:
20563999

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