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Factors Associated with Long-Term Intraocular Pressure Fluctuation in Primary Angle Closure Disease: The CUHK PACG Longitudinal (CUPAL) Study.

Cheung CY, Li SL, Chan N, Wong M, Chan P, Lai I, Baig N, Tan S, Man X, Tang F, Wang YM, Tham CC.

J Glaucoma. 2018 Jun 4. doi: 10.1097/IJG.0000000000000996. [Epub ahead of print]


Risk Factor Analysis for the Outcomes of Indirect Traumatic Optic Neuropathy with No Light Perception at Initial Visual Acuity Testing.

Lai IL, Liao HT.

World Neurosurg. 2018 Jul;115:e620-e628. doi: 10.1016/j.wneu.2018.04.121. Epub 2018 Apr 26.


Laparoscopic distal gastrectomy for clinical stage I gastric adenocarcinoma: Techniques evolution and oncological outcomes of the first 100 cases.

Yeh CC, Yen HH, Lai IR.

J Formos Med Assoc. 2018 Apr 6. pii: S0929-6646(17)30669-1. doi: 10.1016/j.jfma.2018.03.010. [Epub ahead of print]


Anti-miR-17 therapy delays tumorigenesis in MYC-driven hepatocellular carcinoma (HCC).

Dhanasekaran R, Gabay-Ryan M, Baylot V, Lai I, Mosley A, Huang X, Zabludoff S, Li J, Kaimal V, Karmali P, Felsher DW.

Oncotarget. 2017 Nov 9;9(5):5517-5528. doi: 10.18632/oncotarget.22342. eCollection 2018 Jan 19.


Analysis of experience-regulated transcriptome and imprintome during critical periods of mouse visual system development reveals spatiotemporal dynamics.

Hsu CL, Chou CH, Huang SC, Lin CY, Lin MY, Tung CC, Lin CY, Lai IP, Zou YF, Youngson NA, Lin SP, Yang CH, Chen SK, Gau SS, Huang HS.

Hum Mol Genet. 2018 Mar 15;27(6):1039-1054. doi: 10.1093/hmg/ddy023.


Dexmedetomidine Prevents Cognitive Decline by Enhancing Resolution of High Mobility Group Box 1 Protein-induced Inflammation through a Vagomimetic Action in Mice.

Hu J, Vacas S, Feng X, Lutrin D, Uchida Y, Lai IK, Maze M.

Anesthesiology. 2018 May;128(5):921-931. doi: 10.1097/ALN.0000000000002038.


Meibomian Gland Performance in Glaucomatous Patients With Long-term Instillation of IOP-lowering Medications.

Cho WH, Lai IC, Fang PC, Chien CC, Tseng SL, Lai YH, Huang YT, Kuo MT.

J Glaucoma. 2018 Feb;27(2):176-183. doi: 10.1097/IJG.0000000000000841.


Long noncoding RNA MIAT promotes non-small cell lung cancer proliferation and metastasis through MMP9 activation.

Lai IL, Yang CA, Lin PC, Chan WL, Lee YT, Yen JC, Chang YS, Chang JG.

Oncotarget. 2017 Oct 3;8(58):98148-98162. doi: 10.18632/oncotarget.21465. eCollection 2017 Nov 17.


Exosomal TGF-β1 is correlated with lymphatic metastasis of gastric cancers.

Yen EY, Miaw SC, Yu JS, Lai IR.

Am J Cancer Res. 2017 Nov 1;7(11):2199-2208. eCollection 2017.


Active fraction (HS7) from Taiwanofungus camphoratus inhibits AKT-mTOR, ERK and STAT3 pathways and induces CDK inhibitors in CL1-0 human lung cancer cells.

Lai IC, Lai GM, Chow JM, Lee HL, Yeh CF, Li CH, Yan JL, Chuang SE, Whang-Peng J, Bai KJ, Yao CJ.

Chin Med. 2017 Nov 15;12:33. doi: 10.1186/s13020-017-0154-9. eCollection 2017.


Effects of a healthy-eater self-schema and nutrition literacy on healthy-eating behaviors among Taiwanese college students.

Lee CK, Liao LL, Lai IJ, Chang LC.

Health Promot Int. 2017 Nov 14. doi: 10.1093/heapro/dax080. [Epub ahead of print]


Definitive Radiotherapy for Older Patients with Prostate Cancer: Experience of a Medical Center in Taiwan.

Wu YH, Yang WC, Hu YW, Hsieh CM, Yang KL, Lai IC, Hsu CX, Wang TH, Lai TY, Chen KT, Kang YM, Liu YM.

Sci Rep. 2017 Oct 24;7(1):13880. doi: 10.1038/s41598-017-13119-3.


Diagnostic capability of peripapillary retinal nerve fiber layer parameters in time-domain versus spectral-domain optical coherence tomography for assessing glaucoma in high myopia.

Teng MC, Poon YC, Hung KC, Chang HW, Lai IC, Tsai JC, Lin PW, Wu CY, Chen CT, Wu PC.

Int J Ophthalmol. 2017 Jul 18;10(7):1106-1112. doi: 10.18240/ijo.2017.07.14. eCollection 2017.


Construction of Nutrition Literacy Indicators for College Students in Taiwan: A Delphi Consensus Study.

Liao LL, Lai IJ.

J Nutr Educ Behav. 2017 Oct;49(9):734-742.e1. doi: 10.1016/j.jneb.2017.05.351. Epub 2017 Jul 18.


Induction of Forkhead Class box O3a and apoptosis by a standardized ginsenoside formulation, KG-135, is potentiated by autophagy blockade in A549 human lung cancer cells.

Yao CJ, Chow JM, Chuang SE, Chang CL, Yan MD, Lee HL, Lai IC, Lin PC, Lai GM.

J Ginseng Res. 2017 Jul;41(3):247-256. doi: 10.1016/j.jgr.2016.04.003. Epub 2016 Apr 15.


Role of integrin-linked kinase in regulating the protein stability of the MUC1-C oncoprotein in pancreatic cancer cells.

Huang HL, Wu HY, Chu PC, Lai IL, Huang PH, Kulp SK, Pan SL, Teng CM, Chen CS.

Oncogenesis. 2017 Jul 10;6(7):e359. doi: 10.1038/oncsis.2017.61.


Prognostic factors of short-term outcomes of intravitreal ranibizumab in diabetic macular edema.

Lai IA, Hsu WC, Yang CM, Hsieh YT.

Int J Ophthalmol. 2017 May 18;10(5):765-771. doi: 10.18240/ijo.2017.05.18. eCollection 2017.


Effect of a Modified Hospital Elder Life Program on Delirium and Length of Hospital Stay in Patients Undergoing Abdominal Surgery: A Cluster Randomized Clinical Trial.

Chen CC, Li HC, Liang JT, Lai IR, Purnomo JDT, Yang YT, Lin BR, Huang J, Yang CY, Tien YW, Chen CN, Lin MT, Huang GH, Inouye SK.

JAMA Surg. 2017 Sep 1;152(9):827-834. doi: 10.1001/jamasurg.2017.1083.


Use of a numerical simulation approach to improve the estimation of air-water exchange fluxes of polycyclic aromatic hydrocarbons in a coastal zone.

Lai IC, Lee CL, Ko FC, Lin JC, Huang HC, Shiu RF.

Mar Pollut Bull. 2017 Jul 15;120(1-2):259-267. doi: 10.1016/j.marpolbul.2017.05.023. Epub 2017 May 16.


Tracking the Fate and Origin of Clinically Relevant Adoptively Transferred CD8+ T Cells In Vivo.

Chapuis AG, Desmarais C, Emerson R, Schmitt TM, Shibuya K, Lai I, Wagener F, Chou J, Roberts IM, Coffey DG, Warren E, Robbins H, Greenberg PD, Yee C.

Sci Immunol. 2017 Feb;2(8). pii: eaal2568. doi: 10.1126/sciimmunol.aal2568. Epub 2017 Feb 24.


Distinct Clinicopathological Features and Prognosis of Helicobacter pylori Negative Gastric Cancer.

Tsai KF, Liou JM, Chen MJ, Chen CC, Kuo SH, Lai IR, Yeh KH, Lin MT, Wang HP, Cheng AL, Lin JT, Shun CT, Wu MS; Taiwan Gastrointestinal Disease and Helicobacter Consortium.

PLoS One. 2017 Feb 2;12(2):e0170942. doi: 10.1371/journal.pone.0170942. eCollection 2017.


Intraocular pressure fluctuation after water drinking test in primary angle-closure glaucoma and primary open-angle glaucoma.

Poon YC, Teng MC, Lin PW, Tsai JC, Lai IC.

Indian J Ophthalmol. 2016 Dec;64(12):919-923. doi: 10.4103/0301-4738.198851.


DNA-Sensing and Nuclease Gene Expressions as Markers for Colorectal Cancer Progression.

Yang CA, Huang HY, Chang YS, Lin CL, Lai IL, Chang JG.

Oncology. 2017;92(2):115-124. doi: 10.1159/000452281. Epub 2016 Dec 17.


Reflections on a part of the private sector response to the West African Ebola outbreak, 2014-2015.

Lai I, Simpson A.

Med Confl Surviv. 2016 Jul-Sep;32(3):175-183. doi: 10.1080/13623699.2016.1249148. Epub 2016 Nov 2. No abstract available.


microRNA-183 Mediates Protective Postconditioning of the Liver by Repressing Apaf-1.

Lin HC, Liu SY, Yen EY, Li TK, Lai IR.

Antioxid Redox Signal. 2017 Apr 10;26(11):583-597. doi: 10.1089/ars.2016.6679. Epub 2016 Nov 2.


Visual outcomes after spectacles treatment in children with bilateral high refractive amblyopia.

Lin PW, Chang HW, Lai IC, Teng MC.

Clin Exp Optom. 2016 Nov;99(6):550-554. doi: 10.1111/cxo.12412. Epub 2016 Jul 17.


Ultrastrong trapping of VEGF by graphene oxide: Anti-angiogenesis application.

Lai PX, Chen CW, Wei SC, Lin TY, Jian HJ, Lai IP, Mao JY, Hsu PH, Lin HJ, Tzou WS, Chen SY, Harroun SG, Lai JY, Huang CC.

Biomaterials. 2016 Dec;109:12-22. doi: 10.1016/j.biomaterials.2016.09.005. Epub 2016 Sep 13.


Cysts of the canal of Nuck: A rare sonographic diagnosis.

Lai I, Page A, Hamidinia F, Rahmani R.

J Clin Ultrasound. 2017 Mar 4;45(3):175-178. doi: 10.1002/jcu.22390. Epub 2016 Sep 10.


Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation.

Yao CJ, Chow JM, Yang CM, Kuo HC, Chang CL, Lee HL, Lai IC, Chuang SE, Lai GM.

Evid Based Complement Alternat Med. 2016;2016:3251046. doi: 10.1155/2016/3251046. Epub 2016 Jul 20.


T-Cell Therapy Using Interleukin-21-Primed Cytotoxic T-Cell Lymphocytes Combined With Cytotoxic T-Cell Lymphocyte Antigen-4 Blockade Results in Long-Term Cell Persistence and Durable Tumor Regression.

Chapuis AG, Roberts IM, Thompson JA, Margolin KA, Bhatia S, Lee SM, Sloan HL, Lai IP, Farrar EA, Wagener F, Shibuya KC, Cao J, Wolchok JD, Greenberg PD, Yee C.

J Clin Oncol. 2016 Nov 1;34(31):3787-3795. doi: 10.1200/JCO.2015.65.5142.


Combined IL-21-primed polyclonal CTL plus CTLA4 blockade controls refractory metastatic melanoma in a patient.

Chapuis AG, Lee SM, Thompson JA, Roberts IM, Margolin KA, Bhatia S, Sloan HL, Lai I, Wagener F, Shibuya K, Cao J, Wolchok JD, Greenberg PD, Yee C.

J Exp Med. 2016 Jun 27;213(7):1133-9. doi: 10.1084/jem.20152021. Epub 2016 May 30.


Activation of focal adhesion kinase through an interaction with β4 integrin contributes to tumorigenicity of colon cancer.

Tai YL, Lai IR, Peng YJ, Ding ST, Shen TL.

FEBS Lett. 2016 Jun;590(12):1826-37. doi: 10.1002/1873-3468.12215. Epub 2016 May 30.


Effects of a food advertising literacy intervention on Taiwanese children's food purchasing behaviors.

Liao LL, Lai IJ, Chang LC, Lee CK.

Health Educ Res. 2016 Aug;31(4):509-20. doi: 10.1093/her/cyw025. Epub 2016 May 13.


A new grid-scale model simulating the spatiotemporal distribution of PM2.5-PAHs for exposure assessment.

Lee CL, Huang HC, Wang CC, Sheu CC, Wu CC, Leung SY, Lai RS, Lin CC, Wei YF, Lai IC, Jiang H, Chou WL, Chung WY, Huang MS, Huang SK.

J Hazard Mater. 2016 Aug 15;314:286-294. doi: 10.1016/j.jhazmat.2016.04.047. Epub 2016 Apr 22.


The Impacts of Attitudes and Engagement on Electronic Word of Mouth (eWOM) of Mobile Sensor Computing Applications.

Zhao Y, Liu Y, Lai IK, Zhang H, Zhang Y.

Sensors (Basel). 2016 Mar 18;16(3). pii: E391. doi: 10.3390/s16030391.


Mucin glycosylating enzyme GALNT2 suppresses malignancy in gastric adenocarcinoma by reducing MET phosphorylation.

Liu SY, Shun CT, Hung KY, Juan HF, Hsu CL, Huang MC, Lai IR.

Oncotarget. 2016 Mar 8;7(10):11251-62. doi: 10.18632/oncotarget.7081.


Risk Factors Analysis for the Outcome of Indirect Traumatic Optic Neuropathy With Steroid Pulse Therapy.

Lai IL, Liao HT, Chen CT.

Ann Plast Surg. 2016 Mar;76 Suppl 1:S60-7. doi: 10.1097/SAP.0000000000000694.


A new conceptual model for quantifying transboundary contribution of atmospheric pollutants in the East Asian Pacific rim region.

Lai IC, Lee CL, Huang HC.

Environ Int. 2016 Mar;88:160-168. doi: 10.1016/j.envint.2015.12.018. Epub 2016 Jan 4.


Macular Diagnostic Ability in OCT for Assessing Glaucoma in High Myopia.

Hung KC, Wu PC, Poon YC, Chang HW, Lai IC, Tsai JC, Lin PW, Teng MC.

Optom Vis Sci. 2016 Feb;93(2):126-35. doi: 10.1097/OPX.0000000000000776.


The in vitro antioxidant properties of alcalase hydrolysate prepared from silkie fowl (Gallus gallus) blood protein.

Cheng FY, Lai IC, Lin LC, Sakata R.

Anim Sci J. 2016 Jul;87(7):921-8. doi: 10.1111/asj.12509. Epub 2015 Nov 11.


An EGFR/Src-dependent β4 integrin/FAK complex contributes to malignancy of breast cancer.

Tai YL, Chu PY, Lai IR, Wang MY, Tseng HY, Guan JL, Liou JY, Shen TL.

Sci Rep. 2015 Nov 9;5:16408. doi: 10.1038/srep16408.


Preclinical Investigation of the Novel Histone Deacetylase Inhibitor AR-42 in the Treatment of Cancer-Induced Cachexia.

Tseng YC, Kulp SK, Lai IL, Hsu EC, He WA, Frankhouser DE, Yan PS, Mo X, Bloomston M, Lesinski GB, Marcucci G, Guttridge DC, Bekaii-Saab T, Chen CS.

J Natl Cancer Inst. 2015 Oct 12;107(12):djv274. doi: 10.1093/jnci/djv274. Print 2015 Dec.


Can mixed pure hepatocellular carcinoma and germinoma arise together in the brain?

Chen LJ, Lai IC, Wong TT, Lin SC, Ho DM, Chang KP, Guo WY, Yen SH, Chen MT, Chen YW.

J Chin Med Assoc. 2015 Sep;78(9):562-6. doi: 10.1016/j.jcma.2015.02.007. Epub 2015 Aug 20.


Loading of PAX3 to Mitotic Chromosomes Is Mediated by Arginine Methylation and Associated with Waardenburg Syndrome.

Wu TF, Yao YL, Lai IL, Lai CC, Lin PL, Yang WM.

J Biol Chem. 2015 Aug 14;290(33):20556-64. doi: 10.1074/jbc.M114.607713. Epub 2015 Jul 6.


Targeting of multiple oncogenic signaling pathways by Hsp90 inhibitor alone or in combination with berberine for treatment of colorectal cancer.

Su YH, Tang WC, Cheng YW, Sia P, Huang CC, Lee YC, Jiang HY, Wu MH, Lai IL, Lee JW, Lee KH.

Biochim Biophys Acta. 2015 Oct;1853(10 Pt A):2261-72. doi: 10.1016/j.bbamcr.2015.05.012. Epub 2015 May 14.


Pediatric gastric cancer presenting with massive ascites.

Lin CH, Lin WC, Lai IH, Wu SF, Wu KH, Chen AC.

World J Gastroenterol. 2015 Mar 21;21(11):3409-13. doi: 10.3748/wjg.v21.i11.3409.


Dialysate Lavage: An Alternative Solution for Reducing the Peritoneal Implantation of Poorly Differentiated Gastric Cancer Cells.

Liu SY, Jeng JY, Lin HC, Hung KY, Lai IR.

Eur Surg Res. 2015;55(1-2):24-34. doi: 10.1159/000371345. Epub 2015 Mar 5.


Elimination of cancer stem-like cells and potentiation of temozolomide sensitivity by Honokiol in glioblastoma multiforme cells.

Lai IC, Shih PH, Yao CJ, Yeh CT, Wang-Peng J, Lui TN, Chuang SE, Hu TS, Lai TY, Lai GM.

PLoS One. 2015 Mar 12;10(3):e0114830. doi: 10.1371/journal.pone.0114830. eCollection 2015.


Treatment results and prognostic factors for intracranial nongerminomatous germ cell tumors: single institute experience.

Lai IC, Wong TT, Shiau CY, Hu YW, Ho DM, Chang KP, Guo WY, Chang FC, Liang ML, Lee YY, Chen HH, Yen SH, Chen YW.

Childs Nerv Syst. 2015 May;31(5):683-91. doi: 10.1007/s00381-015-2623-8. Epub 2015 Mar 8.


Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling.

Huang MJ, Hu RH, Chou CH, Hsu CL, Liu YW, Huang J, Hung JS, Lai IR, Juan HF, Yu SL, Wu YM, Huang MC.

Oncotarget. 2015 Mar 20;6(8):5650-65.

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