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In situ reconstruction of vascular inflow/outflow to left lateral liver section, ex-vivo liver resection and autologous liver transplantation of remaining liver remnant for hepatic alveolar echinococcosis.

Zhang Y, Lai ECH, Yang C, Yang H, Liu J, Zhou G, Xian D, Deng S, Lau WY.

Int J Surg Case Rep. 2020 Mar 28;69:39-43. doi: 10.1016/j.ijscr.2020.03.023. [Epub ahead of print]


Favorable pleiotropic effects of sodium glucose cotransporter 2 inhibitors: head-to-head comparisons with dipeptidyl peptidase-4 inhibitors in type 2 diabetes patients.

Shao SC, Chang KC, Lin SJ, Chien RN, Hung MJ, Chan YY, Kao Yang YH, Lai EC.

Cardiovasc Diabetol. 2020 Feb 12;19(1):17. doi: 10.1186/s12933-020-0990-2.


Atosiban and Pregnancy Outcomes Following In Vitro Fertilization Treatment for Infertile Women Requiring One, Two, or More Embryo Transfer Cycles: A Longitudinal Cohort Study.

Wu MH, Lin CW, Su PF, Lai EC, Sie FC, Mau YL, Huey NG, Ou HT.

Reprod Sci. 2020 Mar;27(3):853-859. doi: 10.1007/s43032-019-00088-3. Epub 2020 Jan 6.


Sodium glucose co-transporter 2 inhibitors and cardiovascular event protections: how applicable are clinical trials and observational studies to real-world patients?

Shao SC, Lin YH, Chang KC, Chan YY, Hung MJ, Kao Yang YH, Lai EC.

BMJ Open Diabetes Res Care. 2019 Dec;7(1). pii: e000742. doi: 10.1136/bmjdrc-2019-000742.


Using clinical registries, administrative data and electronic medical records to improve medication safety and effectiveness in dementia.

Ilomäki J, Lai EC, Bell JS.

Curr Opin Psychiatry. 2020 Mar;33(2):163-169. doi: 10.1097/YCO.0000000000000579.


Regulation of embryonic and adult neurogenesis by Ars2.

Yu Y, Andreu-Agullo C, Liu BF, Barboza L, Toth M, Lai EC.

Development. 2020 Jan 22;147(2). pii: dev180018. doi: 10.1242/dev.180018.


BEN-solo factors partition active chromatin to ensure proper gene activation in Drosophila.

Ueberschär M, Wang H, Zhang C, Kondo S, Aoki T, Schedl P, Lai EC, Wen J, Dai Q.

Nat Commun. 2019 Dec 13;10(1):5700. doi: 10.1038/s41467-019-13558-8.


Use of hydrochlorothiazide and risk of skin cancer: a nationwide Taiwanese case-control study.

Pottegård A, Pedersen SA, Schmidt SAJ, Lee CN, Hsu CK, Liao TC, Shao SC, Lai EC.

Br J Cancer. 2019 Nov;121(11):973-978. doi: 10.1038/s41416-019-0613-4. Epub 2019 Nov 1.


Comparative risk evaluation for cardiovascular events associated with dapagliflozin vs. empagliflozin in real-world type 2 diabetes patients: a multi-institutional cohort study.

Shao SC, Chang KC, Hung MJ, Yang NI, Chan YY, Chen HY, Kao Yang YH, Lai EC.

Cardiovasc Diabetol. 2019 Sep 24;18(1):120. doi: 10.1186/s12933-019-0919-9.


Interactions between psychiatric and physical disorders and their effects on the risks of suicide: a nested case-control study.

Chang CF, Yeh MK, Chien WC, Chung CH, Li TT, Lai EC.

Ann N Y Acad Sci. 2020 Feb;1462(1):79-91. doi: 10.1111/nyas.14216. Epub 2019 Sep 8.


Effects of sodium-glucose co-transporter-2 inhibitors on serum alanine aminotransferase levels in people with type 2 diabetes: A multi-institutional cohort study.

Shao SC, Chang KC, Chien RN, Lin SJ, Hung MJ, Chan YY, Kao Yang YH, Lai EC.

Diabetes Obes Metab. 2020 Jan;22(1):128-134. doi: 10.1111/dom.13875. Epub 2019 Oct 10.


Cancer-associated mutations in DICER1 RNase IIIa and IIIb domains exert similar effects on miRNA biogenesis.

Vedanayagam J, Chatila WK, Aksoy BA, Majumdar S, Skanderup AJ, Demir E, Schultz N, Sander C, Lai EC.

Nat Commun. 2019 Aug 15;10(1):3682. doi: 10.1038/s41467-019-11610-1.


Letter: contraindicated drug-drug interactions before and after initiation of direct-acting anti-viral agents in chronic hepatitis C patients in Taiwan.

Shao SC, Lai EC, Chang KC, Chan YY, Chen HY, Chien RN.

Aliment Pharmacol Ther. 2019 Jul;50(1):113-115. doi: 10.1111/apt.15303. No abstract available.


Extra-Glissonian Approach for Laparoscopic Liver Right Anterior Sectionectomy.

Chen HW, Wang FJ, Li JY, Deng FW, Lai ECH, Lau WY.

JSLS. 2019 Apr-Jun;23(2). pii: e2019.00009. doi: 10.4293/JSLS.2019.00009.


Taiwan's National Health Insurance Research Database: past and future.

Hsieh CY, Su CC, Shao SC, Sung SF, Lin SJ, Kao Yang YH, Lai EC.

Clin Epidemiol. 2019 May 3;11:349-358. doi: 10.2147/CLEP.S196293. eCollection 2019. Review.


Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in Drosophila.

Mazaud D, Kottler B, Gonçalves-Pimentel C, Proelss S, Tüchler N, Deneubourg C, Yuasa Y, Diebold C, Jungbluth H, Lai EC, Hirth F, Giangrande A, Fanto M.

J Neurosci. 2019 Jul 3;39(27):5269-5283. doi: 10.1523/JNEUROSCI.1833-18.2019. Epub 2019 May 7.


Erratum: Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus.

Mohammed J, Flynt AS, Panzarino AM, Mondal MMH, DeCruz M, Siepel A, Lai EC.

Genome Res. 2019 May;29(5):881. doi: 10.1101/gr.250654.119. No abstract available.


Incidence of type 2 diabetes mellitus in men receiving steroid 5α-reductase inhibitors: population based cohort study.

Wei L, Lai EC, Kao-Yang YH, Walker BR, MacDonald TM, Andrew R.

BMJ. 2019 Apr 10;365:l1204. doi: 10.1136/bmj.l1204.


Increased risk of coronary heart disease among patients with idiopathic inflammatory myositis: a nationwide population study in Taiwan.

Weng MY, Lai EC, Kao Yang YH.

Rheumatology (Oxford). 2019 Nov 1;58(11):1935-1941. doi: 10.1093/rheumatology/kez076.


"Healthcare for Society"-a column featuring outstanding community contributions.

Wong MCS, Lai ECH.

Hong Kong Med J. 2019 Feb;25(1):4-5. doi: 10.12809/hkmj195086. No abstract available.


The Chang Gung Research Database-A multi-institutional electronic medical records database for real-world epidemiological studies in Taiwan.

Shao SC, Chan YY, Kao Yang YH, Lin SJ, Hung MJ, Chien RN, Lai CC, Lai EC.

Pharmacoepidemiol Drug Saf. 2019 May;28(5):593-600. doi: 10.1002/pds.4713. Epub 2019 Jan 16.


Laparoscopic Right Hepatectomy Via an Anterior Approach for Hepatocellular Carcinoma.

Chen HW, Deng FW, Wang FJ, Li JY, Lai ECH, Lau WY.

JSLS. 2018 Jan-Mar;22(1). pii: e2017.00084. doi: 10.4293/JSLS.2017.00084.


Disease and economic burden for rare diseases in Taiwan: A longitudinal study using Taiwan's National Health Insurance Research Database.

Hsu JC, Wu HC, Feng WC, Chou CH, Lai EC, Lu CY.

PLoS One. 2018 Sep 21;13(9):e0204206. doi: 10.1371/journal.pone.0204206. eCollection 2018.


Comparative safety of NSAIDs for gastrointestinal events in Asia-Pacific populations: A multi-database, international cohort study.

Lai EC, Shin JY, Kubota K, Man KKC, Park BJ, Pratt N, Roughead EE, Wong ICK, Kao Yang YH, Setoguchi S.

Pharmacoepidemiol Drug Saf. 2018 Nov;27(11):1223-1230. doi: 10.1002/pds.4663. Epub 2018 Sep 19.


Trends in attention-deficit hyperactivity disorder medication use: a retrospective observational study using population-based databases.

Raman SR, Man KKC, Bahmanyar S, Berard A, Bilder S, Boukhris T, Bushnell G, Crystal S, Furu K, KaoYang YH, Karlstad Ø, Kieler H, Kubota K, Lai EC, Martikainen JE, Maura G, Moore N, Montero D, Nakamura H, Neumann A, Pate V, Pottegård A, Pratt NL, Roughead EE, Macias Saint-Gerons D, Stürmer T, Su CC, Zoega H, Sturkenbroom MCJM, Chan EW, Coghill D, Ip P, Wong ICK.

Lancet Psychiatry. 2018 Oct;5(10):824-835. doi: 10.1016/S2215-0366(18)30293-1. Epub 2018 Sep 13.


Process and Results of Implementing Disease Management Program in Patients with First-time Ischemic Stroke.

Yang HR, Ma L, Jiang YF, Wu YC, Lai EC, Zhu YH.

Iran J Public Health. 2018 Jul;47(7):1007-1016.


DICER1 Is Essential for Self-Renewal of Human Embryonic Stem Cells.

Teijeiro V, Yang D, Majumdar S, González F, Rickert RW, Xu C, Koche R, Verma N, Lai EC, Huangfu D.

Stem Cell Reports. 2018 Sep 11;11(3):616-625. doi: 10.1016/j.stemcr.2018.07.013. Epub 2018 Aug 23.


Therapeutic Duplication of Long-Acting Injectable Drugs.

Shao SC, Lai EC, Chan YY, Hung MJ, Chen HY.

J Patient Saf. 2018 Sep;14(3):e74-e75. doi: 10.1097/PTS.0000000000000526.


Applying a common data model to Asian databases for multinational pharmacoepidemiologic studies: opportunities and challenges.

Lai EC, Ryan P, Zhang Y, Schuemie M, Hardy NC, Kamijima Y, Kimura S, Kubota K, Man KK, Cho SY, Park RW, Stang P, Su CC, Wong IC, Kao YY, Setoguchi S.

Clin Epidemiol. 2018 Jul 27;10:875-885. doi: 10.2147/CLEP.S149961. eCollection 2018.


The hpRNA/RNAi Pathway Is Essential to Resolve Intragenomic Conflict in the Drosophila Male Germline.

Lin CJ, Hu F, Dubruille R, Vedanayagam J, Wen J, Smibert P, Loppin B, Lai EC.

Dev Cell. 2018 Aug 6;46(3):316-326.e5. doi: 10.1016/j.devcel.2018.07.004.


Look-Alike Medication Packages and Patient Safety.

Shao SC, Lai EC, Owang KL, Chen HY, Chan YY.

J Patient Saf. 2018 Sep;14(3):e47-e48. doi: 10.1097/PTS.0000000000000506.


Fractures and the increased risk of suicide: a population-based case-control study.

Chang CF, Lai EC, Yeh MK.

Bone Joint J. 2018 Jun 1;100-B(6):780-786. doi: 10.1302/0301-620X.100B6.BJJ-2017-1183.R2.


Revisiting monovision for presbyopia.

Mahrous A, Ciralsky JB, Lai EC.

Curr Opin Ophthalmol. 2018 Jul;29(4):313-317. doi: 10.1097/ICU.0000000000000487. Review.


Cystic artery pseudoaneurysm with haemobilia after laparoscopic cholecystectomy.

To K, Lai EC, Chung DT, Chan OC, Tang CN.

Hong Kong Med J. 2018 Apr;24(2):203-205. doi: 10.12809/hkmj176236. No abstract available.


Usability and Validation of the Smarter Balance System: An Unsupervised Dynamic Balance Exercises System for Individuals With Parkinson's Disease.

Fung A, Lai EC, Lee BC.

IEEE Trans Neural Syst Rehabil Eng. 2018 Apr;26(4):798-806. doi: 10.1109/TNSRE.2018.2808139.


Short cryptic exons mediate recursive splicing in Drosophila.

Joseph B, Kondo S, Lai EC.

Nat Struct Mol Biol. 2018 May;25(5):365-371. doi: 10.1038/s41594-018-0052-6. Epub 2018 Apr 9.


Methotrexate-induced pancytopenia in a patient with ectopic pregnancy.

Shao SC, Yang YK, Chien PS, Lai EC.

Arch Med Sci. 2018 Mar;14(2):475-476. doi: 10.5114/aoms.2016.58844. Epub 2016 Mar 23. No abstract available.


The mir-279/996 cluster represses receptor tyrosine kinase signaling to determine cell fates in the Drosophila eye.

Duan H, de Navas LF, Hu F, Sun K, Mavromatakis YE, Viets K, Zhou C, Kavaler J, Johnston RJ, Tomlinson A, Lai EC.

Development. 2018 Apr 9;145(7). pii: dev159053. doi: 10.1242/dev.159053.


Dual Strategies for Argonaute2-Mediated Biogenesis of Erythroid miRNAs Underlie Conserved Requirements for Slicing in Mammals.

Jee D, Yang JS, Park SM, Farmer DT, Wen J, Chou T, Chow A, McManus MT, Kharas MG, Lai EC.

Mol Cell. 2018 Jan 18;69(2):265-278.e6. doi: 10.1016/j.molcel.2017.12.027.


Deep experimental profiling of microRNA diversity, deployment, and evolution across the Drosophila genus.

Mohammed J, Flynt AS, Panzarino AM, Mondal MMH, DeCruz M, Siepel A, Lai EC.

Genome Res. 2018 Jan;28(1):52-65. doi: 10.1101/gr.226068.117. Epub 2017 Dec 12. Erratum in: Genome Res. 2019 May;29(5):881.


miRNA suppression of a Notch repressor directs non-neuronal fate in Drosophila mechanosensory organs.

Kavaler J, Duan H, Aradhya R, de Navas LF, Joseph B, Shklyar B, Lai EC.

J Cell Biol. 2018 Feb 5;217(2):571-583. doi: 10.1083/jcb.201706101. Epub 2017 Dec 1.


Landscape and evolution of tissue-specific alternative polyadenylation across Drosophila species.

Sanfilippo P, Wen J, Lai EC.

Genome Biol. 2017 Nov 30;18(1):229. doi: 10.1186/s13059-017-1358-0.


Robotic transduodenal excision of ampullary tumour.

Wong FCH, Lai ECH, Chung DTM, Tang CN.

Hepatobiliary Surg Nutr. 2017 Oct;6(5):312-316. doi: 10.21037/hbsn.2016.12.04.


New genes often acquire male-specific functions but rarely become essential in Drosophila.

Kondo S, Vedanayagam J, Mohammed J, Eizadshenass S, Kan L, Pang N, Aradhya R, Siepel A, Steinhauer J, Lai EC.

Genes Dev. 2017 Sep 15;31(18):1841-1846. doi: 10.1101/gad.303131.117.


Extra-glissonian Approach for Total Laparoscopic Left Hepatectomy: A Prospective Cohort Study.

Chen HW, Deng FW, Hu JY, Li JY, Lai ECH, Lau WY.

Surg Laparosc Endosc Percutan Tech. 2017 Dec;27(6):e145-e148. doi: 10.1097/SLE.0000000000000483.


Doctor for Society: paying tribute to role models of humanitarianism and professionalism.

Lai EC, Wong MC.

Hong Kong Med J. 2017 Oct;23(5):432. doi: 10.12809/hkmj175071. No abstract available.


Training robotic hepatectomy: the Hong Kong experience and perspective.

Lai ECH, Tang CN.

Hepatobiliary Surg Nutr. 2017 Aug;6(4):222-229. doi: 10.21037/hbsn.2017.01.21. Review.


Modifications of ALPPS - from complex to more complex or from complex to less complex operations.

Lau WY, Lai EC.

Hepatobiliary Pancreat Dis Int. 2017 Aug 15;16(4):346-352. doi: 10.1016/S1499-3872(17)60034-1. Review.


Genome-wide identification of Grainy head targets in Drosophila reveals regulatory interactions with the POU domain transcription factor Vvl.

Yao L, Wang S, Westholm JO, Dai Q, Matsuda R, Hosono C, Bray S, Lai EC, Samakovlis C.

Development. 2017 Sep 1;144(17):3145-3155. doi: 10.1242/dev.143297. Epub 2017 Jul 31.

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