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Items: 21


NeoPeptide: an immunoinformatic database of T-cell-defined neoantigens.

Zhou WJ, Qu Z, Song CY, Sun Y, Lai AL, Luo MY, Ying YZ, Meng H, Liang Z, He YJ, Li YH, Liu J.

Database (Oxford). 2019 Jan 1;2019. pii: baz128. doi: 10.1093/database/baz128.


Calcium Ions Directly Interact with the Ebola Virus Fusion Peptide To Promote Structure-Function Changes That Enhance Infection.

Nathan L, Lai AL, Millet JK, Straus MR, Freed JH, Whittaker GR, Daniel S.

ACS Infect Dis. 2019 Dec 10. doi: 10.1021/acsinfecdis.9b00296. [Epub ahead of print]


Extradural cervical spinal meningioma mimicking malignancy.

Lai AL, Salkade PR, Chuah KL, Sitoh YY.

J Radiol Case Rep. 2018 Oct 31;12(10):1-10. doi: 10.3941/jrcr.v12i10.3498. eCollection 2018 Oct.


The SARS-CoV Fusion Peptide Forms an Extended Bipartite Fusion Platform that Perturbs Membrane Order in a Calcium-Dependent Manner.

Lai AL, Millet JK, Daniel S, Freed JH, Whittaker GR.

J Mol Biol. 2017 Dec 8;429(24):3875-3892. doi: 10.1016/j.jmb.2017.10.017. Epub 2017 Oct 19.


Unique Structural Features of Membrane-Bound C-Terminal Domain Motifs Modulate Complexin Inhibitory Function.

Snead D, Lai AL, Wragg RT, Parisotto DA, Ramlall TF, Dittman JS, Freed JH, Eliezer D.

Front Mol Neurosci. 2017 May 24;10:154. doi: 10.3389/fnmol.2017.00154. eCollection 2017.


Key features of an Hsp70 chaperone allosteric landscape revealed by ion-mobility native mass spectrometry and double electron-electron resonance.

Lai AL, Clerico EM, Blackburn ME, Patel NA, Robinson CV, Borbat PP, Freed JH, Gierasch LM.

J Biol Chem. 2017 May 26;292(21):8773-8785. doi: 10.1074/jbc.M116.770404. Epub 2017 Apr 20.


Structure-Function Studies Link Class II Viral Fusogens with the Ancestral Gamete Fusion Protein HAP2.

Pinello JF, Lai AL, Millet JK, Cassidy-Hanley D, Freed JH, Clark TG.

Curr Biol. 2017 Mar 6;27(5):651-660. doi: 10.1016/j.cub.2017.01.049. Epub 2017 Feb 23.


The Interaction between Influenza HA Fusion Peptide and Transmembrane Domain Affects Membrane Structure.

Lai AL, Freed JH.

Biophys J. 2015 Dec 15;109(12):2523-2536. doi: 10.1016/j.bpj.2015.10.044.


HIV gp41 fusion peptide increases membrane ordering in a cholesterol-dependent fashion.

Lai AL, Freed JH.

Biophys J. 2014 Jan 7;106(1):172-81. doi: 10.1016/j.bpj.2013.11.027.


Fusion activity of HIV gp41 fusion domain is related to its secondary structure and depth of membrane insertion in a cholesterol-dependent fashion.

Lai AL, Moorthy AE, Li Y, Tamm LK.

J Mol Biol. 2012 Apr 20;418(1-2):3-15. doi: 10.1016/j.jmb.2012.02.010. Epub 2012 Feb 17.


Synaptotagmin 1 modulates lipid acyl chain order in lipid bilayers by demixing phosphatidylserine.

Lai AL, Tamm LK, Ellena JF, Cafiso DS.

J Biol Chem. 2011 Jul 15;286(28):25291-300. doi: 10.1074/jbc.M111.258848. Epub 2011 May 24.


Synaptotagmin 1 and SNAREs form a complex that is structurally heterogeneous.

Lai AL, Huang H, Herrick DZ, Epp N, Cafiso DS.

J Mol Biol. 2011 Jan 21;405(3):696-706. doi: 10.1016/j.jmb.2010.11.015. Epub 2010 Nov 16.


Shallow boomerang-shaped influenza hemagglutinin G13A mutant structure promotes leaky membrane fusion.

Lai AL, Tamm LK.

J Biol Chem. 2010 Nov 26;285(48):37467-75. doi: 10.1074/jbc.M110.153700. Epub 2010 Sep 8.


Diagnostic criteria for eosinophilic esophagitis: a 5-year retrospective review in a pediatric population.

Lai AL, Girgis S, Liang Y, Carr S, Huynh HQ.

J Pediatr Gastroenterol Nutr. 2009 Jul;49(1):63-70. doi: 10.1097/MPG.0b013e318184c917.


Combined NMR and EPR spectroscopy to determine structures of viral fusion domains in membranes.

Tamm LK, Lai AL, Li Y.

Biochim Biophys Acta. 2007 Dec;1768(12):3052-60. Epub 2007 Sep 25. Review.


Locking the kink in the influenza hemagglutinin fusion domain structure.

Lai AL, Tamm LK.

J Biol Chem. 2007 Aug 17;282(33):23946-56. Epub 2007 Jun 12.


[Comparison of different antidepression therapy in perimenopausal and postmenopausal women with depression].

Lai AL, Zhao YW, Qi HY, Zhang JS, Zhang LS, Weng YQ.

Zhonghua Fu Chan Ke Za Zhi. 2007 Mar;42(3):169-72. Chinese.


Fusion peptide of influenza hemagglutinin requires a fixed angle boomerang structure for activity.

Lai AL, Park H, White JM, Tamm LK.

J Biol Chem. 2006 Mar 3;281(9):5760-70. Epub 2005 Dec 28.


ATP-mediated conformational changes in the RecA filament.

VanLoock MS, Yu X, Yang S, Lai AL, Low C, Campbell MJ, Egelman EH.

Structure. 2003 Feb;11(2):187-96.


Structure and function of membrane fusion peptides.

Tamm LK, Han X, Li Y, Lai AL.

Biopolymers. 2002;66(4):249-60. Review.


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