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Items: 1 to 50 of 221

1.

An arginine residue involved in allosteric regulation of cystathionine β-synthase (CBS) domain-containing pyrophosphatase.

Anashkin VA, Orlov VN, Lahti R, Baykov AA.

Arch Biochem Biophys. 2019 Feb 15;662:40-48. doi: 10.1016/j.abb.2018.11.024. Epub 2018 Nov 28.

PMID:
30502330
2.

Role of the potassium/lysine cationic center in catalysis and functional asymmetry in membrane-bound pyrophosphatases.

Artukka E, Luoto HH, Baykov AA, Lahti R, Malinen AM.

Biochem J. 2018 Mar 26;475(6):1141-1158. doi: 10.1042/BCJ20180071.

PMID:
29519958
3.

Enzymes Regulated via Cystathionine β-Synthase Domains.

Anashkin VA, Baykov AA, Lahti R.

Biochemistry (Mosc). 2017 Oct;82(10):1079-1087. doi: 10.1134/S0006297917100017. Review.

PMID:
29037129
4.

Inorganic pyrophosphatases of Family II-two decades after their discovery.

Baykov AA, Anashkin VA, Salminen A, Lahti R.

FEBS Lett. 2017 Oct;591(20):3225-3234. doi: 10.1002/1873-3468.12877. Epub 2017 Oct 17. Review.

5.

Two independent evolutionary routes to Na+/H+ cotransport function in membrane pyrophosphatases.

Nordbo E, Luoto HH, Baykov AA, Lahti R, Malinen AM.

Biochem J. 2016 Oct 1;473(19):3099-111. doi: 10.1042/BCJ20160529. Epub 2016 Aug 3.

PMID:
27487839
6.

An asparagine residue mediates intramolecular communication in nucleotide-regulated pyrophosphatase.

Anashkin VA, Salminen A, Vorobjeva NN, Lahti R, Baykov AA.

Biochem J. 2016 Jul 15;473(14):2097-107. doi: 10.1042/BCJ20160293. Epub 2016 May 17.

PMID:
27208172
7.

Cystathionine β-Synthase (CBS) Domain-containing Pyrophosphatase as a Target for Diadenosine Polyphosphates in Bacteria.

Anashkin VA, Salminen A, Tuominen HK, Orlov VN, Lahti R, Baykov AA.

J Biol Chem. 2015 Nov 13;290(46):27594-603. doi: 10.1074/jbc.M115.680272. Epub 2015 Sep 23.

8.

Cytochrome cbb3 of Thioalkalivibrio is a Na+-pumping cytochrome oxidase.

Muntyan MS, Cherepanov DA, Malinen AM, Bloch DA, Sorokin DY, Severina II, Ivashina TV, Lahti R, Muyzer G, Skulachev VP.

Proc Natl Acad Sci U S A. 2015 Jun 23;112(25):7695-700. doi: 10.1073/pnas.1417071112. Epub 2015 Jun 8.

9.

Evolutionarily divergent, Na+-regulated H+-transporting membrane-bound pyrophosphatases.

Luoto HH, Nordbo E, Malinen AM, Baykov AA, Lahti R.

Biochem J. 2015 Apr 15;467(2):281-91. doi: 10.1042/BJ20141434.

PMID:
25662511
10.

Cause and manner of death and phase of the blood alcohol curve.

Lahti RA, Pitkäniemi J, Jones AW, Sajantila A, Poikolainen K, Vuori E.

Forensic Sci Int. 2014 Nov;244:306-12.

PMID:
25452205
11.

Cystathionine β-synthase (CBS) domains confer multiple forms of Mg2+-dependent cooperativity to family II pyrophosphatases.

Salminen A, Anashkin VA, Lahti M, Tuominen HK, Lahti R, Baykov AA.

J Biol Chem. 2014 Aug 15;289(33):22865-76. doi: 10.1074/jbc.M114.589473. Epub 2014 Jul 1.

12.

Membrane Na+-pyrophosphatases can transport protons at low sodium concentrations.

Luoto HH, Nordbo E, Baykov AA, Lahti R, Malinen AM.

J Biol Chem. 2013 Dec 6;288(49):35489-99. doi: 10.1074/jbc.M113.510909. Epub 2013 Oct 24.

13.

Pyrophosphate-fueled Na+ and H+ transport in prokaryotes.

Baykov AA, Malinen AM, Luoto HH, Lahti R.

Microbiol Mol Biol Rev. 2013 Jun;77(2):267-76. doi: 10.1128/MMBR.00003-13. Review. Erratum in: Microbiol Mol Biol Rev. 2013 Sep;77(3):540.

14.

Membrane-integral pyrophosphatase subfamily capable of translocating both Na+ and H+.

Luoto HH, Baykov AA, Lahti R, Malinen AM.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1255-60. doi: 10.1073/pnas.1217816110. Epub 2013 Jan 7.

15.

Fast kinetics of nucleotide binding to Clostridium perfringens family II pyrophosphatase containing CBS and DRTGG domains.

Jämsen J, Baykov AA, Lahti R.

Biochemistry (Mosc). 2012 Feb;77(2):165-70. doi: 10.1134/S0006297912020071.

PMID:
22348476
16.

The CBS domain: a protein module with an emerging prominent role in regulation.

Baykov AA, Tuominen HK, Lahti R.

ACS Chem Biol. 2011 Nov 18;6(11):1156-63. doi: 10.1021/cb200231c. Epub 2011 Oct 11. Review.

PMID:
21958115
17.

Under-recording of ethanol intoxication and poisoning in cause-of-death data: causes and consequences.

Lahti RA, Sajantila A, Korpi H, Poikolainen K, Vuori E.

Forensic Sci Int. 2011 Oct 10;212(1-3):121-5. doi: 10.1016/j.forsciint.2011.05.029. Epub 2011 Jun 25.

PMID:
21708436
18.

Na+-translocating membrane pyrophosphatases are widespread in the microbial world and evolutionarily precede H+-translocating pyrophosphatases.

Luoto HH, Belogurov GA, Baykov AA, Lahti R, Malinen AM.

J Biol Chem. 2011 Jun 17;286(24):21633-42. doi: 10.1074/jbc.M111.244483. Epub 2011 Apr 28.

19.

Mutational analysis of residues in the regulatory CBS domains of Moorella thermoacetica pyrophosphatase corresponding to disease-related residues of human proteins.

Jämsen J, Tuominen H, Baykov AA, Lahti R.

Biochem J. 2011 Feb 1;433(3):497-504. doi: 10.1042/BJ20101204.

PMID:
21067517
20.

Crystal structures of the CBS and DRTGG domains of the regulatory region of Clostridiumperfringens pyrophosphatase complexed with the inhibitor, AMP, and activator, diadenosine tetraphosphate.

Tuominen H, Salminen A, Oksanen E, Jämsen J, Heikkilä O, Lehtiö L, Magretova NN, Goldman A, Baykov AA, Lahti R.

J Mol Biol. 2010 May 7;398(3):400-13. doi: 10.1016/j.jmb.2010.03.019. Epub 2010 Mar 19.

PMID:
20303981
21.

Nucleotide- and substrate-induced conformational transitions in the CBS domain-containing pyrophosphatase of Moorella thermoacetica.

Jämsen J, Baykov AA, Lahti R.

Biochemistry. 2010 Feb 9;49(5):1005-13. doi: 10.1021/bi9019737.

PMID:
20038140
22.

Blood-positive illicit-drug findings: implications for cause-of-death certification, classification and coding.

Lahti RA, Korpi H, Vuori E.

Forensic Sci Int. 2009 May 30;187(1-3):14-8. doi: 10.1016/j.forsciint.2009.02.007. Epub 2009 Mar 19.

PMID:
19303228
23.

Mutual effects of cationic ligands and substrate on activity of the Na+-transporting pyrophosphatase of Methanosarcina mazei.

Malinen AM, Baykov AA, Lahti R.

Biochemistry. 2008 Dec 16;47(50):13447-54. doi: 10.1021/bi801803b.

PMID:
19053266
24.

Human metastasis regulator protein H-prune is a short-chain exopolyphosphatase.

Tammenkoski M, Koivula K, Cusanelli E, Zollo M, Steegborn C, Baykov AA, Lahti R.

Biochemistry. 2008 Sep 9;47(36):9707-13. doi: 10.1021/bi8010847. Epub 2008 Aug 14.

PMID:
18700747
25.

A CBS domain-containing pyrophosphatase of Moorella thermoacetica is regulated by adenine nucleotides.

Jämsen J, Tuominen H, Salminen A, Belogurov GA, Magretova NN, Baykov AA, Lahti R.

Biochem J. 2007 Dec 15;408(3):327-33.

26.

Stimulating and inhibitory effects of the dopamine "stabilizer" (-)-OSU6162 on dopamine D2 receptor function in vitro.

Lahti RA, Tamminga CA, Carlsson A.

J Neural Transm (Vienna). 2007 Sep;114(9):1143-6. Epub 2007 Jul 6.

PMID:
17612788
27.

Na+-pyrophosphatase: a novel primary sodium pump.

Malinen AM, Belogurov GA, Baykov AA, Lahti R.

Biochemistry. 2007 Jul 31;46(30):8872-8. Epub 2007 Jul 3.

PMID:
17605473
28.

A complete structural description of the catalytic cycle of yeast pyrophosphatase.

Oksanen E, Ahonen AK, Tuominen H, Tuominen V, Lahti R, Goldman A, Heikinheimo P.

Biochemistry. 2007 Feb 6;46(5):1228-39.

PMID:
17260952
29.

Kinetic and mutational analyses of the major cytosolic exopolyphosphatase from Saccharomyces cerevisiae.

Tammenkoski M, Moiseev VM, Lahti M, Ugochukwu E, Brondijk TH, White SA, Lahti R, Baykov AA.

J Biol Chem. 2007 Mar 30;282(13):9302-11. Epub 2007 Jan 10.

30.

A trimetal site and substrate distortion in a family II inorganic pyrophosphatase.

Fabrichniy IP, Lehtiö L, Tammenkoski M, Zyryanov AB, Oksanen E, Baykov AA, Lahti R, Goldman A.

J Biol Chem. 2007 Jan 12;282(2):1422-31. Epub 2006 Nov 8.

31.

Two soluble pyrophosphatases in Vibrio cholerae: transient redundancy or enduring cooperation?

Salminen A, Ilias M, Belogurov GA, Baykov AA, Lahti R, Young T.

Biochemistry (Mosc). 2006 Sep;71(9):978-82.

32.

An unusual, His-dependent family I pyrophosphatase from Mycobacterium tuberculosis.

Tammenkoski M, Benini S, Magretova NN, Baykov AA, Lahti R.

J Biol Chem. 2005 Dec 23;280(51):41819-26. Epub 2005 Oct 20.

33.

Inhibition of family II pyrophosphatases by analogs of pyrophosphate and phosphate.

Zyryanov AB, Lahti R, Baykov AA.

Biochemistry (Mosc). 2005 Aug;70(8):908-12.

PMID:
16212547
34.

Effects of active site mutations on the metal binding affinity, catalytic competence, and stability of the family II pyrophosphatase from Bacillus subtilis.

Halonen P, Tammenkoski M, Niiranen L, Huopalahti S, Parfenyev AN, Goldman A, Baykov A, Lahti R.

Biochemistry. 2005 Mar 15;44(10):4004-10.

PMID:
15751976
35.

Membrane-bound pyrophosphatase of Thermotoga maritima requires sodium for activity.

Belogurov GA, Malinen AM, Turkina MV, Jalonen U, Rytkönen K, Baykov AA, Lahti R.

Biochemistry. 2005 Feb 15;44(6):2088-96.

PMID:
15697234
36.

Structural studies of metal ions in family II pyrophosphatases: the requirement for a Janus ion.

Fabrichniy IP, Lehtiö L, Salminen A, Zyryanov AB, Baykov AA, Lahti R, Goldman A.

Biochemistry. 2004 Nov 16;43(45):14403-11.

PMID:
15533045
37.

Site-specific effects of zinc on the activity of family II pyrophosphatase.

Zyryanov AB, Tammenkoski M, Salminen A, Kolomiytseva GY, Fabrichniy IP, Goldman A, Lahti R, Baykov AA.

Biochemistry. 2004 Nov 16;43(45):14395-402.

PMID:
15533044
38.

Cd(2+)-induced aggregation of Escherichia coli pyrophosphatase.

Zimenkov YV, Salminen A, Efimova IS, Lahti R, Baykov AA.

Eur J Biochem. 2004 Jul;271(14):3064-7.

39.

Initial experience with mass immunization as a bioterrorism countermeasure.

Folio LR, Lahti RL, Cockrum DS, Bills S, Younker MR.

J Am Osteopath Assoc. 2004 Jun;104(6):240-3.

PMID:
15233330
40.

Regional expression of RGS4 mRNA in human brain.

Erdely HA, Lahti RA, Lopez MB, Myers CS, Roberts RC, Tamminga CA, Vogel MW.

Eur J Neurosci. 2004 Jun;19(11):3125-8.

PMID:
15182322
41.

Elucidating the role of conserved glutamates in H+-pyrophosphatase of Rhodospirillum rubrum.

Malinen AM, Belogurov GA, Salminen M, Baykov AA, Lahti R.

J Biol Chem. 2004 Jun 25;279(26):26811-6. Epub 2004 Apr 23.

42.

Production and preliminary analysis of perdeuterated yeast inorganic pyrophosphatase crystals suitable for neutron diffraction.

Tuominen VU, Myles DA, Dauvergne MT, Lahti R, Heikinheimo P, Goldman A.

Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):606-9. Epub 2004 Feb 25.

PMID:
14993708
43.

Rates of elementary catalytic steps for different metal forms of the family II pyrophosphatase from Streptococcus gordonii.

Zyryanov AB, Vener AV, Salminen A, Goldman A, Lahti R, Baykov AA.

Biochemistry. 2004 Feb 3;43(4):1065-74.

PMID:
14744152
44.

Fatal drug poisonings: medico-legal reports and mortality statistics.

Lahti RA, Vuori E.

Forensic Sci Int. 2003 Sep 9;136(1-3):35-46.

PMID:
12969618
45.
46.
47.

Single-turnover kinetics of Saccharomyces cerevisiae inorganic pyrophosphatase.

Halonen P, Baykov AA, Goldman A, Lahti R, Cooperman BS.

Biochemistry. 2002 Oct 8;41(40):12025-31.

PMID:
12356302
48.

Mechanism by which metal cofactors control substrate specificity in pyrophosphatase.

Zyryanov AB, Shestakov AS, Lahti R, Baykov AA.

Biochem J. 2002 Nov 1;367(Pt 3):901-6.

49.

Fatal alcohol poisoning: medico-legal practices and mortality statistics.

Lahti RA, Vuori E.

Forensic Sci Int. 2002 May 23;126(3):203-9.

PMID:
12062942
50.

H+-pyrophosphatase of Rhodospirillum rubrum. High yield expression in Escherichia coli and identification of the Cys residues responsible for inactivation my mersalyl.

Belogurov GA, Turkina MV, Penttinen A, Huopalahti S, Baykov AA, Lahti R.

J Biol Chem. 2002 Jun 21;277(25):22209-14. Epub 2002 Apr 15.

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