Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 80


Lifestyle and cancer-a joint pairwise association of lifestyle habits with subsequent cancer diagnosis.

Roos ET, Lahti JM, Rahkonen O.

Eur J Public Health. 2019 Apr 1;29(2):340-345. doi: 10.1093/eurpub/cky184.


An epigenetic clock for gestational age at birth based on blood methylation data.

Knight AK, Craig JM, Theda C, Bækvad-Hansen M, Bybjerg-Grauholm J, Hansen CS, Hollegaard MV, Hougaard DM, Mortensen PB, Weinsheimer SM, Werge TM, Brennan PA, Cubells JF, Newport DJ, Stowe ZN, Cheong JL, Dalach P, Doyle LW, Loke YJ, Baccarelli AA, Just AC, Wright RO, Téllez-Rojo MM, Svensson K, Trevisi L, Kennedy EM, Binder EB, Iurato S, Czamara D, Räikkönen K, Lahti JM, Pesonen AK, Kajantie E, Villa PM, Laivuori H, Hämäläinen E, Park HJ, Bailey LB, Parets SE, Kilaru V, Menon R, Horvath S, Bush NR, LeWinn KZ, Tylavsky FA, Conneely KN, Smith AK.

Genome Biol. 2016 Oct 7;17(1):206.


The effect of personality on daily life emotional processes.

Komulainen E, Meskanen K, Lipsanen J, Lahti JM, Jylhä P, Melartin T, Wichers M, Isometsä E, Ekelund J.

PLoS One. 2014 Oct 24;9(10):e110907. doi: 10.1371/journal.pone.0110907. eCollection 2014.


Roles of ChlR1 DNA helicase in replication recovery from DNA damage.

Shah N, Inoue A, Woo Lee S, Beishline K, Lahti JM, Noguchi E.

Exp Cell Res. 2013 Aug 15;319(14):2244-53. doi: 10.1016/j.yexcr.2013.06.005. Epub 2013 Jun 22.


Th-MYCN mice with caspase-8 deficiency develop advanced neuroblastoma with bone marrow metastasis.

Teitz T, Inoue M, Valentine MB, Zhu K, Rehg JE, Zhao W, Finkelstein D, Wang YD, Johnson MD, Calabrese C, Rubinstein M, Hakem R, Weiss WA, Lahti JM.

Cancer Res. 2013 Jul 1;73(13):4086-97. doi: 10.1158/0008-5472.CAN-12-2681. Epub 2013 Mar 27.


Tetraspanin CD82 inhibits protrusion and retraction in cell movement by attenuating the plasma membrane-dependent actin organization.

Liu WM, Zhang F, Moshiach S, Zhou B, Huang C, Srinivasan K, Khurana S, Zheng Y, Lahti JM, Zhang XA.

PLoS One. 2012;7(12):e51797. doi: 10.1371/journal.pone.0051797. Epub 2012 Dec 14.


CHK2 kinase promotes pre-mRNA splicing via phosphorylating CDK11(p110).

Choi HH, Choi HK, Jung SY, Hyle J, Kim BJ, Yoon K, Cho EJ, Youn HD, Lahti JM, Qin J, Kim ST.

Oncogene. 2014 Jan 2;33(1):108-15. doi: 10.1038/onc.2012.535. Epub 2012 Nov 26.


Mammalian ChlR1 has a role in heterochromatin organization.

Inoue A, Hyle J, Lechner MS, Lahti JM.

Exp Cell Res. 2011 Oct 15;317(17):2522-35. doi: 10.1016/j.yexcr.2011.08.006. Epub 2011 Aug 11.


Tetraspanin CD151 maintains vascular stability by balancing the forces of cell adhesion and cytoskeletal tension.

Zhang F, Michaelson JE, Moshiach S, Sachs N, Zhao W, Sun Y, Sonnenberg A, Lahti JM, Huang H, Zhang XA.

Blood. 2011 Oct 13;118(15):4274-84. doi: 10.1182/blood-2011-03-339531. Epub 2011 Aug 10. Erratum in: Blood. 2014 Jun 12;123(24):3843.


Preclinical models for neuroblastoma: establishing a baseline for treatment.

Teitz T, Stanke JJ, Federico S, Bradley CL, Brennan R, Zhang J, Johnson MD, Sedlacik J, Inoue M, Zhang ZM, Frase S, Rehg JE, Hillenbrand CM, Finkelstein D, Calabrese C, Dyer MA, Lahti JM.

PLoS One. 2011 Apr 29;6(4):e19133. doi: 10.1371/journal.pone.0019133.


Chromosome damage and repair in children with sickle cell anaemia and long-term hydroxycarbamide exposure.

McGann PT, Howard TA, Flanagan JM, Lahti JM, Ware RE.

Br J Haematol. 2011 Jul;154(1):134-40. doi: 10.1111/j.1365-2141.2011.08698.x. Epub 2011 May 4.


The connections between neural crest development and neuroblastoma.

Jiang M, Stanke J, Lahti JM.

Curr Top Dev Biol. 2011;94:77-127. doi: 10.1016/B978-0-12-380916-2.00004-8. Review.


The RNA binding motif protein 15B (RBM15B/OTT3) is a functional competitor of serine-arginine (SR) proteins and antagonizes the positive effect of the CDK11p110-cyclin L2α complex on splicing.

Loyer P, Busson A, Trembley JH, Hyle J, Grenet J, Zhao W, Ribault C, Montier T, Kidd VJ, Lahti JM.

J Biol Chem. 2011 Jan 7;286(1):147-59. doi: 10.1074/jbc.M110.192518. Epub 2010 Nov 2.


Phase I study of decitabine with doxorubicin and cyclophosphamide in children with neuroblastoma and other solid tumors: a Children's Oncology Group study.

George RE, Lahti JM, Adamson PC, Zhu K, Finkelstein D, Ingle AM, Reid JM, Krailo M, Neuberg D, Blaney SM, Diller L.

Pediatr Blood Cancer. 2010 Oct;55(4):629-38. doi: 10.1002/pbc.22607.


Cyclin-dependent kinases: a family portrait.

Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ.

Nat Cell Biol. 2009 Nov;11(11):1275-6. doi: 10.1038/ncb1109-1275. No abstract available.


Synthetic mRNA splicing modulator compounds with in vivo antitumor activity.

Lagisetti C, Pourpak A, Goronga T, Jiang Q, Cui X, Hyle J, Lahti JM, Morris SW, Webb TR.

J Med Chem. 2009 Nov 26;52(22):6979-90. doi: 10.1021/jm901215m.


Caspase-8 association with the focal adhesion complex promotes tumor cell migration and metastasis.

Barbero S, Mielgo A, Torres V, Teitz T, Shields DJ, Mikolon D, Bogyo M, Barilà D, Lahti JM, Schlaepfer D, Stupack DG.

Cancer Res. 2009 May 1;69(9):3755-63. doi: 10.1158/0008-5472.CAN-08-3937. Epub 2009 Apr 21.


Perturbation of HP1 localization and chromatin binding ability causes defects in sister-chromatid cohesion.

Inoue A, Hyle J, Lechner MS, Lahti JM.

Mutat Res. 2008 Nov 17;657(1):48-55. doi: 10.1016/j.mrgentox.2008.08.010. Epub 2008 Aug 26.


Retinoic acid induces caspase-8 transcription via phospho-CREB and increases apoptotic responses to death stimuli in neuroblastoma cells.

Jiang M, Zhu K, Grenet J, Lahti JM.

Biochim Biophys Acta. 2008 Jun;1783(6):1055-67. doi: 10.1016/j.bbamcr.2008.02.007. Epub 2008 Mar 10.


Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.

Loyer P, Trembley JH, Grenet JA, Busson A, Corlu A, Zhao W, Kocak M, Kidd VJ, Lahti JM.

J Biol Chem. 2008 Mar 21;283(12):7721-32. doi: 10.1074/jbc.M708188200. Epub 2008 Jan 23.


The microenvironmental determinants for kidney epithelial cyst morphogenesis.

Guo Q, Xia B, Moshiach S, Xu C, Jiang Y, Chen Y, Sun Y, Lahti JM, Zhang XA.

Eur J Cell Biol. 2008 Apr;87(4):251-66. doi: 10.1016/j.ejcb.2007.11.004. Epub 2008 Jan 8.


Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

Inoue A, Li T, Roby SK, Valentine MB, Inoue M, Boyd K, Kidd VJ, Lahti JM.

Cell Cycle. 2007 Jul 1;6(13):1646-54. Epub 2007 May 8.


CDK11(p58) is required for the maintenance of sister chromatid cohesion.

Hu D, Valentine M, Kidd VJ, Lahti JM.

J Cell Sci. 2007 Jul 15;120(Pt 14):2424-34.


Two isoforms of the human cyclin C gene are expressed differentially suggesting that they may have distinct functions.

Katona RL, Loyer P, Roby SK, Lahti JM.

Acta Biol Hung. 2007 Mar;58(1):133-7.


The DNA helicase ChlR1 is required for sister chromatid cohesion in mammalian cells.

Parish JL, Rosa J, Wang X, Lahti JM, Doxsey SJ, Androphy EJ.

J Cell Sci. 2006 Dec 1;119(Pt 23):4857-65. Epub 2006 Nov 14.


Evaluation of IFN-gamma effects on apoptosis and gene expression in neuroblastoma--preclinical studies.

Tekautz TM, Zhu K, Grenet J, Kaushal D, Kidd VJ, Lahti JM.

Biochim Biophys Acta. 2006 Oct;1763(10):1000-10. Epub 2006 Aug 9.


Does integrin-mediated cell death confer tissue tropism in metastasis?

Lahti JM, Teitz T, Stupack DG.

Cancer Res. 2006 Jun 15;66(12):5981-4. Review.


Identification of an ataxia telangiectasia-mutated protein mediated surveillance system to regulate Bcl-2 overexpression.

Zhang J, Lahti JM, Bruce A, He L, Parihar K, Fan C, Grenet J, Liu L, Kidd VJ, Cormier S, Tang D.

Oncogene. 2006 Sep 14;25(41):5601-11. Epub 2006 Apr 24.


Caspase-8 promotes cell motility and calpain activity under nonapoptotic conditions.

Helfer B, Boswell BC, Finlay D, Cipres A, Vuori K, Bong Kang T, Wallach D, Dorfleutner A, Lahti JM, Flynn DC, Frisch SM.

Cancer Res. 2006 Apr 15;66(8):4273-8.


Halting neuroblastoma metastasis by controlling integrin-mediated death.

Teitz T, Stupack DG, Lahti JM.

Cell Cycle. 2006 Apr;5(7):681-5. Epub 2006 Apr 1.


Potentiation of neuroblastoma metastasis by loss of caspase-8.

Stupack DG, Teitz T, Potter MD, Mikolon D, Houghton PJ, Kidd VJ, Lahti JM, Cheresh DA.

Nature. 2006 Jan 5;439(7072):95-9.


Role of CDK/cyclin complexes in transcription and RNA splicing.

Loyer P, Trembley JH, Katona R, Kidd VJ, Lahti JM.

Cell Signal. 2005 Sep;17(9):1033-51. Review.


Cyclin dependent kinase 11 in RNA transcription and splicing.

Trembley JH, Loyer P, Hu D, Li T, Grenet J, Lahti JM, Kidd VJ.

Prog Nucleic Acid Res Mol Biol. 2004;77:263-88. Review. No abstract available.


The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription.

Hsu LC, Liu S, Abedinpour F, Beech RD, Lahti JM, Kidd VJ, Greenspan JA, Yeung CY.

Mol Cell Biol. 2003 Dec;23(23):8773-85.


Prevalence of necrosis in C2-ceramide-induced cytotoxicity in NB16 neuroblastoma cells.

Ramos B, Lahti JM, Claro E, Jackowski S.

Mol Pharmacol. 2003 Aug;64(2):502-11.


ASAP, a novel protein complex involved in RNA processing and apoptosis.

Schwerk C, Prasad J, Degenhardt K, Erdjument-Bromage H, White E, Tempst P, Kidd VJ, Manley JL, Lahti JM, Reinberg D.

Mol Cell Biol. 2003 Apr;23(8):2981-90.


CDK11 complexes promote pre-mRNA splicing.

Hu D, Mayeda A, Trembley JH, Lahti JM, Kidd VJ.

J Biol Chem. 2003 Mar 7;278(10):8623-9. Epub 2002 Dec 24.


Caspase-9 and Apaf-1 are expressed and functionally active in human neuroblastoma tumor cell lines with 1p36 LOH and amplified MYCN.

Teitz T, Wei T, Liu D, Valentine V, Valentine M, Grenet J, Lahti JM, Kidd VJ.

Oncogene. 2002 Mar 14;21(12):1848-58.


ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53.

Tang D, Wu D, Hirao A, Lahti JM, Liu L, Mazza B, Kidd VJ, Mak TW, Ingram AJ.

J Biol Chem. 2002 Apr 12;277(15):12710-7. Epub 2002 Jan 30.


PITSLRE p110 protein kinases associate with transcription complexes and affect their activity.

Trembley JH, Hu D, Hsu LC, Yeung CY, Slaughter C, Lahti JM, Kidd VJ.

J Biol Chem. 2002 Jan 25;277(4):2589-96. Epub 2001 Nov 14.


Aggressive childhood neuroblastomas do not express caspase-8: an important component of programmed cell death.

Teitz T, Lahti JM, Kidd VJ.

J Mol Med (Berl). 2001 Aug;79(8):428-36. Review.


Proteolytic regulation of apoptosis.

Kidd VJ, Lahti JM, Teitz T.

Semin Cell Dev Biol. 2000 Jun;11(3):191-201. Review.


Caspase 8 is deleted or silenced preferentially in childhood neuroblastomas with amplification of MYCN.

Teitz T, Wei T, Valentine MB, Vanin EF, Grenet J, Valentine VA, Behm FG, Look AT, Lahti JM, Kidd VJ.

Nat Med. 2000 May;6(5):529-35.


Characterization of the enzymatic activity of hChlR1, a novel human DNA helicase.

Hirota Y, Lahti JM.

Nucleic Acids Res. 2000 Feb 15;28(4):917-24.


Use of gene knockouts in cultured cells to study apoptosis.

Lahti JM.

Methods. 1999 Apr;17(4):305-12.


Supplemental Content

Loading ...
Support Center