Sort by
Items per page

Send to

Choose Destination

Search results

Items: 46


Conjugation of an scFab domain to the oligomeric HIV envelope protein for use in immune targeting.

King HAD, Gonelli CA, Tullett KM, Lahoud MH, Purcell DFJ, Drummer HE, Poumbourios P, Center RJ.

PLoS One. 2019 Aug 20;14(8):e0220986. doi: 10.1371/journal.pone.0220986. eCollection 2019.


Zymosan by-passes the requirement for pulmonary antigen encounter in lung tissue-resident memory CD8+ T cell development.

Caminschi I, Lahoud MH, Pizzolla A, Wakim LM.

Mucosal Immunol. 2019 Mar;12(2):403-412. doi: 10.1038/s41385-018-0124-2. Epub 2019 Jan 21.


Classical Type 1 Dendritic Cells Dominate Priming of Th1 Responses to Herpes Simplex Virus Type 1 Skin Infection.

Harpur CM, Kato Y, Dewi ST, Stankovic S, Johnson DN, Bedoui S, Whitney PG, Lahoud MH, Caminschi I, Heath WR, Brooks AG, Gebhardt T.

J Immunol. 2019 Feb 1;202(3):653-663. doi: 10.4049/jimmunol.1800218. Epub 2018 Dec 31.


CD8+ T Cell Activation Leads to Constitutive Formation of Liver Tissue-Resident Memory T Cells that Seed a Large and Flexible Niche in the Liver.

Holz LE, Prier JE, Freestone D, Steiner TM, English K, Johnson DN, Mollard V, Cozijnsen A, Davey GM, Godfrey DI, Yui K, Mackay LK, Lahoud MH, Caminschi I, McFadden GI, Bertolino P, Fernandez-Ruiz D, Heath WR.

Cell Rep. 2018 Oct 2;25(1):68-79.e4. doi: 10.1016/j.celrep.2018.08.094.


Self-adjuvanting nanoemulsion targeting dendritic cell receptor Clec9A enables antigen-specific immunotherapy.

Zeng B, Middelberg AP, Gemiarto A, MacDonald K, Baxter AG, Talekar M, Moi D, Tullett KM, Caminschi I, Lahoud MH, Mazzieri R, Dolcetti R, Thomas R.

J Clin Invest. 2018 May 1;128(5):1971-1984. doi: 10.1172/JCI96791. Epub 2018 Apr 9.


Enhancing vaccine antibody responses by targeting Clec9A on dendritic cells.

Park HY, Tan PS, Kavishna R, Ker A, Lu J, Chan CEZ, Hanson BJ, MacAry PA, Caminschi I, Shortman K, Alonso S, Lahoud MH.

NPJ Vaccines. 2017 Nov 6;2:31. doi: 10.1038/s41541-017-0033-5. eCollection 2017.


Local Modulation of Antigen-Presenting Cell Development after Resolution of Pneumonia Induces Long-Term Susceptibility to Secondary Infections.

Roquilly A, McWilliam HEG, Jacqueline C, Tian Z, Cinotti R, Rimbert M, Wakim L, Caminschi I, Lahoud MH, Belz GT, Kallies A, Mintern JD, Asehnoune K, Villadangos JA.

Immunity. 2017 Jul 18;47(1):135-147.e5. doi: 10.1016/j.immuni.2017.06.021.


Antibody-mediated targeting of antigen to C-type lectin-like receptors Clec9A and Clec12A elicits different vaccination outcomes.

Macri C, Dumont C, Panozza S, Lahoud MH, Caminschi I, Villadangos JA, Johnston AP, Mintern JD.

Mol Immunol. 2017 Jan;81:143-150. doi: 10.1016/j.molimm.2016.12.010. Epub 2016 Dec 12.


CD14 is not involved in the uptake of synthetic CpG oligonucleotides.

Li J, Ahmet F, O'Keeffe M, Lahoud MH, Heath WR, Caminschi I.

Mol Immunol. 2017 Jan;81:52-58. doi: 10.1016/j.molimm.2016.11.015. Epub 2016 Dec 12.


Targeting CLEC9A delivers antigen to human CD141+ DC for CD4+ and CD8+T cell recognition.

Tullett KM, Leal Rojas IM, Minoda Y, Tan PS, Zhang JG, Smith C, Khanna R, Shortman K, Caminschi I, Lahoud MH, Radford KJ.

JCI Insight. 2016 May 19;1(7):e87102. doi: 10.1172/jci.insight.87102.


IL-12p40/IL-10 Producing preCD8α/Clec9A+ Dendritic Cells Are Induced in Neonates upon Listeria monocytogenes Infection.

Torres D, Köhler A, Delbauve S, Caminschi I, Lahoud MH, Shortman K, Flamand V.

PLoS Pathog. 2016 Apr 13;12(4):e1005561. doi: 10.1371/journal.ppat.1005561. eCollection 2016 Apr.


Differential uptake and cross-presentation of soluble and necrotic cell antigen by human DC subsets.

Chiang MC, Tullett KM, Lee YS, Idris A, Ding Y, McDonald KJ, Kassianos A, Leal Rojas IM, Jeet V, Lahoud MH, Radford KJ.

Eur J Immunol. 2016 Feb;46(2):329-39. doi: 10.1002/eji.201546023. Epub 2015 Nov 23.


Targeting Antigen to Clec9A Primes Follicular Th Cell Memory Responses Capable of Robust Recall.

Kato Y, Zaid A, Davey GM, Mueller SN, Nutt SL, Zotos D, Tarlinton DM, Shortman K, Lahoud MH, Heath WR, Caminschi I.

J Immunol. 2015 Aug 1;195(3):1006-14. doi: 10.4049/jimmunol.1500767. Epub 2015 Jun 22.


Antibody-targeted vaccination to lung dendritic cells generates tissue-resident memory CD8 T cells that are highly protective against influenza virus infection.

Wakim LM, Smith J, Caminschi I, Lahoud MH, Villadangos JA.

Mucosal Immunol. 2015 Sep;8(5):1060-71. doi: 10.1038/mi.2014.133. Epub 2015 Jan 14.


Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates.

Li J, Ahmet F, Sullivan LC, Brooks AG, Kent SJ, De Rose R, Salazar AM, Reis e Sousa C, Shortman K, Lahoud MH, Heath WR, Caminschi I.

Eur J Immunol. 2015 Mar;45(3):854-64. doi: 10.1002/eji.201445127. Epub 2015 Jan 14.


Harnessing Human Cross-Presenting CLEC9A(+)XCR1(+) Dendritic Cells for Immunotherapy.

Tullett KM, Lahoud MH, Radford KJ.

Front Immunol. 2014 May 22;5:239. doi: 10.3389/fimmu.2014.00239. eCollection 2014. Review. No abstract available.


Dendritic cells and cancer immunotherapy.

Radford KJ, Tullett KM, Lahoud MH.

Curr Opin Immunol. 2014 Apr;27:26-32. doi: 10.1016/j.coi.2014.01.005. Epub 2014 Feb 8. Review.


FLT3-ligand treatment of humanized mice results in the generation of large numbers of CD141+ and CD1c+ dendritic cells in vivo.

Ding Y, Wilkinson A, Idris A, Fancke B, O'Keeffe M, Khalil D, Ju X, Lahoud MH, Caminschi I, Shortman K, Rodwell R, Vuckovic S, Radford KJ.

J Immunol. 2014 Feb 15;192(4):1982-9. doi: 10.4049/jimmunol.1302391. Epub 2014 Jan 22.


Evolution of B cell responses to Clec9A-targeted antigen.

Park HY, Light A, Lahoud MH, Caminschi I, Tarlinton DM, Shortman K.

J Immunol. 2013 Nov 15;191(10):4919-25. doi: 10.4049/jimmunol.1301947. Epub 2013 Oct 11.


Modulation of monosodium urate crystal-induced responses in neutrophils by the myeloid inhibitory C-type lectin-like receptor: potential therapeutic implications.

Gagné V, Marois L, Levesque JM, Galarneau H, Lahoud MH, Caminschi I, Naccache PH, Tessier P, Fernandes MJ.

Arthritis Res Ther. 2013 Jul 9;15(4):R73. doi: 10.1186/ar4250.


Receptor-specific delivery of protein antigen to dendritic cells by a nanoemulsion formed using top-down non-covalent click self-assembly.

Zeng BJ, Chuan YP, O'Sullivan B, Caminschi I, Lahoud MH, Thomas R, Middelberg AP.

Small. 2013 Nov 25;9(22):3736-42. doi: 10.1002/smll.201300078. Epub 2013 Apr 18.


Anti-CD2 producing pig xenografts effect localized depletion of human T cells in a huSCID model.

Brady JL, Sutherland RM, Hancock M, Kitsoulis S, Lahoud MH, Phillips PM, Hawthorne WJ, d'Apice AJ, Cowan PJ, Harrison LC, O'Connell PJ, Lew AM.

Xenotransplantation. 2013 Mar-Apr;20(2):100-9. doi: 10.1111/xen.12025. Epub 2013 Feb 27.


DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats.

Wang Y, Wang YM, Wang Y, Zheng G, Zhang GY, Zhou JJ, Tan TK, Cao Q, Hu M, Watson D, Wu H, Zheng D, Wang C, Lahoud MH, Caminschi I, Harris DC, Alexander SI.

Kidney Int. 2013 Feb;83(2):223-32. doi: 10.1038/ki.2012.374. Epub 2012 Dec 5.


DEC-205 is a cell surface receptor for CpG oligonucleotides.

Lahoud MH, Ahmet F, Zhang JG, Meuter S, Policheni AN, Kitsoulis S, Lee CN, O'Keeffe M, Sullivan LC, Brooks AG, Berry R, Rossjohn J, Mintern JD, Vega-Ramos J, Villadangos JA, Nicola NA, Nussenzweig MC, Stacey KJ, Shortman K, Heath WR, Caminschi I.

Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16270-5. doi: 10.1073/pnas.1208796109. Epub 2012 Sep 17.


The dendritic cell receptor Clec9A binds damaged cells via exposed actin filaments.

Zhang JG, Czabotar PE, Policheni AN, Caminschi I, Wan SS, Kitsoulis S, Tullett KM, Robin AY, Brammananth R, van Delft MF, Lu J, O'Reilly LA, Josefsson EC, Kile BT, Chin WJ, Mintern JD, Olshina MA, Wong W, Baum J, Wright MD, Huang DC, Mohandas N, Coppel RL, Colman PM, Nicola NA, Shortman K, Lahoud MH.

Immunity. 2012 Apr 20;36(4):646-57. doi: 10.1016/j.immuni.2012.03.009. Epub 2012 Apr 5.


Antibody responses initiated by Clec9A-bearing dendritic cells in normal and Batf3(-/-) mice.

Caminschi I, Vremec D, Ahmet F, Lahoud MH, Villadangos JA, Murphy KM, Heath WR, Shortman K.

Mol Immunol. 2012 Feb;50(1-2):9-17. doi: 10.1016/j.molimm.2011.11.008. Epub 2011 Dec 29.


CD103+ pulmonary dendritic cells preferentially acquire and present apoptotic cell-associated antigen.

Desch AN, Randolph GJ, Murphy K, Gautier EL, Kedl RM, Lahoud MH, Caminschi I, Shortman K, Henson PM, Jakubzick CV.

J Exp Med. 2011 Aug 29;208(9):1789-97. doi: 10.1084/jem.20110538. Epub 2011 Aug 22.


Targeting antigen to mouse dendritic cells via Clec9A induces potent CD4 T cell responses biased toward a follicular helper phenotype.

Lahoud MH, Ahmet F, Kitsoulis S, Wan SS, Vremec D, Lee CN, Phipson B, Shi W, Smyth GK, Lew AM, Kato Y, Mueller SN, Davey GM, Heath WR, Shortman K, Caminschi I.

J Immunol. 2011 Jul 15;187(2):842-50. doi: 10.4049/jimmunol.1101176. Epub 2011 Jun 15.


Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A.

Idoyaga J, Lubkin A, Fiorese C, Lahoud MH, Caminschi I, Huang Y, Rodriguez A, Clausen BE, Park CG, Trumpfheller C, Steinman RM.

Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2384-9. doi: 10.1073/pnas.1019547108. Epub 2011 Jan 24.


Induction of antigen-specific effector-phase tolerance following vaccination against a previously ignored B-cell lymphoma.

Prato S, Mintern JD, Lahoud MH, Huang DC, Villadangos JA.

Immunol Cell Biol. 2011 Jul;89(5):595-603. doi: 10.1038/icb.2010.131. Epub 2010 Nov 16.


Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases.

van Delft MF, Smith DP, Lahoud MH, Huang DC, Adams JM.

Cell Death Differ. 2010 May;17(5):821-32. doi: 10.1038/cdd.2009.166. Epub 2009 Nov 13.


The C-type lectin Clec12A present on mouse and human dendritic cells can serve as a target for antigen delivery and enhancement of antibody responses.

Lahoud MH, Proietto AI, Ahmet F, Kitsoulis S, Eidsmo L, Wu L, Sathe P, Pietersz S, Chang HW, Walker ID, Maraskovsky E, Braley H, Lew AM, Wright MD, Heath WR, Shortman K, Caminschi I.

J Immunol. 2009 Jun 15;182(12):7587-94. doi: 10.4049/jimmunol.0900464.


Improving vaccines by targeting antigens to dendritic cells.

Shortman K, Lahoud MH, Caminschi I.

Exp Mol Med. 2009 Feb 28;41(2):61-6. Review.


Enhancing immune responses by targeting antigen to DC.

Caminschi I, Lahoud MH, Shortman K.

Eur J Immunol. 2009 Apr;39(4):931-8. doi: 10.1002/eji.200839035.


Dendritic cells in the thymus contribute to T-regulatory cell induction.

Proietto AI, van Dommelen S, Zhou P, Rizzitelli A, D'Amico A, Steptoe RJ, Naik SH, Lahoud MH, Liu Y, Zheng P, Shortman K, Wu L.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19869-74. doi: 10.1073/pnas.0810268105. Epub 2008 Dec 10. Erratum in: Proc Natl Acad Sci U S A. 2009 Feb 3;106(5):1679.


Distinct functional capacities of mouse thymic and splenic dendritic cell populations.

Proietto AI, Lahoud MH, Wu L.

Immunol Cell Biol. 2008 Nov-Dec;86(8):700-8. doi: 10.1038/icb.2008.63. Epub 2008 Sep 9. Erratum in: Immunol Cell Biol. 2009 Feb;87(2):190.


The dendritic cell subtype-restricted C-type lectin Clec9A is a target for vaccine enhancement.

Caminschi I, Proietto AI, Ahmet F, Kitsoulis S, Shin Teh J, Lo JC, Rizzitelli A, Wu L, Vremec D, van Dommelen SL, Campbell IK, Maraskovsky E, Braley H, Davey GM, Mottram P, van de Velde N, Jensen K, Lew AM, Wright MD, Heath WR, Shortman K, Lahoud MH.

Blood. 2008 Oct 15;112(8):3264-73. doi: 10.1182/blood-2008-05-155176. Epub 2008 Jul 30.


Putative IKDCs are functionally and developmentally similar to natural killer cells, but not to dendritic cells.

Caminschi I, Ahmet F, Heger K, Brady J, Nutt SL, Vremec D, Pietersz S, Lahoud MH, Schofield L, Hansen DS, O'Keeffe M, Smyth MJ, Bedoui S, Davey GM, Villadangos JA, Heath WR, Shortman K.

J Exp Med. 2007 Oct 29;204(11):2579-90. Epub 2007 Oct 8.


Signal regulatory protein molecules are differentially expressed by CD8- dendritic cells.

Lahoud MH, Proietto AI, Gartlan KH, Kitsoulis S, Curtis J, Wettenhall J, Sofi M, Daunt C, O'keeffe M, Caminschi I, Satterley K, Rizzitelli A, Schnorrer P, Hinohara A, Yamaguchi Y, Wu L, Smyth G, Handman E, Shortman K, Wright MD.

J Immunol. 2006 Jul 1;177(1):372-82.


Cutting edge: generation of splenic CD8+ and CD8- dendritic cell equivalents in Fms-like tyrosine kinase 3 ligand bone marrow cultures.

Naik SH, Proietto AI, Wilson NS, Dakic A, Schnorrer P, Fuchsberger M, Lahoud MH, O'Keeffe M, Shao QX, Chen WF, Villadangos JA, Shortman K, Wu L.

J Immunol. 2005 Jun 1;174(11):6592-7.


Differential production of inflammatory chemokines by murine dendritic cell subsets.

Proietto AI, O'Keeffe M, Gartlan K, Wright MD, Shortman K, Wu L, Lahoud MH.

Immunobiology. 2004;209(1-2):163-72.


Mouse plasmacytoid cells: long-lived cells, heterogeneous in surface phenotype and function, that differentiate into CD8(+) dendritic cells only after microbial stimulus.

O'Keeffe M, Hochrein H, Vremec D, Caminschi I, Miller JL, Anders EM, Wu L, Lahoud MH, Henri S, Scott B, Hertzog P, Tatarczuch L, Shortman K.

J Exp Med. 2002 Nov 18;196(10):1307-19.


Gene targeting of Desrt, a novel ARID class DNA-binding protein, causes growth retardation and abnormal development of reproductive organs.

Lahoud MH, Ristevski S, Venter DJ, Jermiin LS, Bertoncello I, Zavarsek S, Hasthorpe S, Drago J, de Kretser D, Hertzog PJ, Kola I.

Genome Res. 2001 Aug;11(8):1327-34.


Choice of mouse strains for gene targeting.

Lahoud MH, Wilson TJ, Hertzog PJ.

Methods Mol Biol. 2001;158:107-19. Review. No abstract available.


Down's syndrome-like skeletal abnormalities in Ets2 transgenic mice.

Sumarsono SH, Wilson TJ, Tymms MJ, Venter DJ, Corrick CM, Kola R, Lahoud MH, Papas TS, Seth A, Kola I.

Nature. 1996 Feb 8;379(6565):534-7.


Construction of a mouse blastocyst cDNA library by PCR amplification from total RNA.

Corrick CM, Silvestro MJ, Lahoud MH, Allen GJ, Tymms MJ, Kola I.

Mol Reprod Dev. 1996 Jan;43(1):7-16.


Supplemental Content

Loading ...
Support Center