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Items: 1 to 50 of 61

1.

A Free Web-Based Protocol to Assist Structure-Based Virtual Screening Experiments.

Lagarde N, Goldwaser E, Pencheva T, Jereva D, Pajeva I, Rey J, Tuffery P, Villoutreix BO, Miteva MA.

Int J Mol Sci. 2019 Sep 19;20(18). pii: E4648. doi: 10.3390/ijms20184648.

2.

New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments.

Dufies M, Grytsai O, Ronco C, Camara O, Ambrosetti D, Hagege A, Parola J, Mateo L, Ayrault M, Giuliano S, Grépin R, Lagarde N, Montes M, Auberger P, Demange L, Benhida R, Pagès G.

Theranostics. 2019 Jul 9;9(18):5332-5346. doi: 10.7150/thno.34681. eCollection 2019. Review.

3.

Nuclear Receptors Database Including Negative Data (NR-DBIND): A Database Dedicated to Nuclear Receptors Binding Data Including Negative Data and Pharmacological Profile.

Réau M, Lagarde N, Zagury JF, Montes M.

J Med Chem. 2019 Mar 28;62(6):2894-2904. doi: 10.1021/acs.jmedchem.8b01105. Epub 2018 Nov 6.

PMID:
30354114
4.

Online structure-based screening of purchasable approved drugs and natural compounds: retrospective examples of drug repositioning on cancer targets.

Lagarde N, Rey J, Gyulkhandanyan A, Tufféry P, Miteva MA, Villoutreix BO.

Oncotarget. 2018 Aug 17;9(64):32346-32361. doi: 10.18632/oncotarget.25966. eCollection 2018 Aug 17.

5.

Hidden partners: Using cross-docking calculations to predict binding sites for proteins with multiple interactions.

Lagarde N, Carbone A, Sacquin-Mora S.

Proteins. 2018 Jul;86(7):723-737. doi: 10.1002/prot.25506. Epub 2018 Apr 24.

PMID:
29664226
6.

Decoys Selection in Benchmarking Datasets: Overview and Perspectives.

Réau M, Langenfeld F, Zagury JF, Lagarde N, Montes M.

Front Pharmacol. 2018 Jan 24;9:11. doi: 10.3389/fphar.2018.00011. eCollection 2018. Review.

7.

New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling.

Rayar AM, Lagarde N, Martin F, Blanchard F, Liagre B, Ferroud C, Zagury JF, Montes M, Sylla-Iyarreta Veitía M.

Eur J Med Chem. 2018 Feb 25;146:577-587. doi: 10.1016/j.ejmech.2018.01.054. Epub 2018 Jan 31.

PMID:
29407982
8.

Update on COX-2 Selective Inhibitors: Chemical Classification, Side Effects and their Use in Cancers and Neuronal Diseases.

Rayar AM, Lagarde N, Ferroud C, Zagury JF, Montes M, Sylla-Iyarreta Veitia M.

Curr Top Med Chem. 2017;17(26):2935-2956. doi: 10.2174/1568026617666170821124947. Review.

PMID:
28828990
9.

Discriminating Agonist from Antagonist Ligands of the Nuclear Receptors Using Different Chemoinformatics Approaches.

Lagarde N, Delahaye S, Jérémie A, Ben Nasr N, Guillemain H, Empereur-Mot C, Laville V, Labib T, Réau M, Langenfeld F, Zagury JF, Montes M.

Mol Inform. 2017 Oct;36(10). doi: 10.1002/minf.201700020. Epub 2017 Jul 3.

PMID:
28671755
10.

Discriminating agonist and antagonist ligands of the nuclear receptors using 3D-pharmacophores.

Lagarde N, Delahaye S, Zagury JF, Montes M.

J Cheminform. 2016 Sep 6;8(1):43. doi: 10.1186/s13321-016-0154-2. eCollection 2016.

11.

IL-7R signaling in regulatory T cells maintains peripheral and allograft tolerance in mice.

Schmaler M, Broggi MA, Lagarde N, Stöcklin BF, King CG, Finke D, Rossi SW.

Proc Natl Acad Sci U S A. 2015 Oct 27;112(43):13330-5. doi: 10.1073/pnas.1510045112. Epub 2015 Oct 8.

12.

A de novo microdeletion of SEMA5A in a boy with autism spectrum disorder and intellectual disability.

Mosca-Boidron AL, Gueneau L, Huguet G, Goldenberg A, Henry C, Gigot N, Pallesi-Pocachard E, Falace A, Duplomb L, Thevenon J, Duffourd Y, St-Onge J, Chambon P, Rivière JB, Thauvin-Robinet C, Callier P, Marle N, Payet M, Ragon C, Goubran Botros H, Buratti J, Calderari S, Dumas G, Delorme R, Lagarde N, Pinoit JM, Rosier A, Masurel-Paulet A, Cardoso C, Mugneret F, Saugier-Veber P, Campion D, Faivre L, Bourgeron T.

Eur J Hum Genet. 2016 Jun;24(6):838-43. doi: 10.1038/ejhg.2015.211. Epub 2015 Sep 23.

13.

Benchmarking Data Sets for the Evaluation of Virtual Ligand Screening Methods: Review and Perspectives.

Lagarde N, Zagury JF, Montes M.

J Chem Inf Model. 2015 Jul 27;55(7):1297-307. doi: 10.1021/acs.jcim.5b00090. Epub 2015 Jun 18. Review.

PMID:
26038804
14.

Morphological and immunohistochemical pattern of tubo-ovarian dysplasia and serous tubal intraepithelial carcinoma.

Chene G, Cayre A, Raoelfils I, Lagarde N, Dauplat J, Penault-Llorca F.

Eur J Obstet Gynecol Reprod Biol. 2014 Dec;183:89-95. doi: 10.1016/j.ejogrb.2014.10.003. Epub 2014 Oct 14.

PMID:
25461359
15.

Importance of the pharmacological profile of the bound ligand in enrichment on nuclear receptors: toward the use of experimentally validated decoy ligands.

Lagarde N, Zagury JF, Montes M.

J Chem Inf Model. 2014 Oct 27;54(10):2915-44. doi: 10.1021/ci500305c. Epub 2014 Oct 9.

PMID:
25250508
16.

Isolation of murine lymph node stromal cells.

Broggi MA, Schmaler M, Lagarde N, Rossi SW.

J Vis Exp. 2014 Aug 19;(90):e51803. doi: 10.3791/51803.

17.

NRLiSt BDB, the manually curated nuclear receptors ligands and structures benchmarking database.

Lagarde N, Ben Nasr N, Jérémie A, Guillemain H, Laville V, Labib T, Zagury JF, Montes M.

J Med Chem. 2014 Apr 10;57(7):3117-25. doi: 10.1021/jm500132p. Epub 2014 Mar 25.

PMID:
24666037
18.

α- and β-hydrazino acid-based pseudopeptides inhibit the chymotrypsin-like activity of the eukaryotic 20S proteasome.

Bordessa A, Keita M, Maréchal X, Formicola L, Lagarde N, Rodrigo J, Bernadat G, Bauvais C, Soulier JL, Dufau L, Milcent T, Crousse B, Reboud-Ravaux M, Ongeri S.

Eur J Med Chem. 2013;70:505-24. doi: 10.1016/j.ejmech.2013.09.059. Epub 2013 Oct 17.

PMID:
24185380
19.

Additional evidence to support the role of the 20q13.33 region in susceptibility to autism.

Mosca-Boidron AL, Valduga M, Thauvin-Robinet C, Lagarde N, Marle N, Henry C, Pinoit JM, Huet F, Béri-Deixheimer M, Ragon C, Gueneau L, Payet M, Callier P, Mugneret F, Jonveaux P, Faivre L.

Am J Med Genet A. 2013 Jun;161A(6):1505-7. doi: 10.1002/ajmg.a.35878. Epub 2013 Apr 23. No abstract available.

PMID:
23613186
20.

[Breast cancer in Finistère, France: epidemiological description and tendencies over a 10-year period (2000-2009) according to pathology data].

Lietard C, Conan V, Le Fur JM, Minot JP, Le Callonec M, Brisseau C, Saliou P, Lejeune B, Lagarde N, Garlantézec R.

Ann Pathol. 2013 Feb;33(1):38-48. doi: 10.1016/j.annpat.2012.09.196. Epub 2013 Feb 11. French.

PMID:
23472894
21.

Multiple structures for virtual ligand screening: defining binding site properties-based criteria to optimize the selection of the query.

Ben Nasr N, Guillemain H, Lagarde N, Zagury JF, Montes M.

J Chem Inf Model. 2013 Feb 25;53(2):293-311. doi: 10.1021/ci3004557. Epub 2013 Jan 29.

PMID:
23312043
22.

Is There a Relationship between Ovarian Epithelial Dysplasia and Infertility?

Chene G, Penault-Llorca F, Tardieu A, Cayre A, Lagarde N, Jaffeux P, Aublet-Cuvelier B, Dechelotte P, Felloni B, Pouly JL, Dauplat J.

Obstet Gynecol Int. 2012;2012:429085. doi: 10.1155/2012/429085. Epub 2012 Feb 9.

23.

Mixture of hyaluronic acid, chondroitin 6 sulphate and dermatan sulphate used to completely regenerate bone in rat critical size defect model.

Zanchetta P, Lagarde N, Uguen A, Marcorelles P.

J Craniomaxillofac Surg. 2012 Dec;40(8):783-7. doi: 10.1016/j.jcms.2012.02.011. Epub 2012 Mar 30.

PMID:
22464550
24.

Antiproliferative activity of trans-avicennol from Zanthoxylum chiloperone var. angustifolium against human cancer stem cells.

Cebrián-Torrejón G, Assad Kahn S, Lagarde N, Castellano F, Leblanc K, Rodrigo J, Molinier-Frenkel V, Rojas de Arias A, Ferreira ME, Thirant C, Fournet A, Figadère B, Chneiweiss H, Poupon E.

J Nat Prod. 2012 Feb 24;75(2):257-61. doi: 10.1021/np2004165. Epub 2012 Feb 3.

PMID:
22304006
25.

Human annexin A6 interacts with influenza a virus protein M2 and negatively modulates infection.

Ma H, Kien F, Manière M, Zhang Y, Lagarde N, Tse KS, Poon LL, Nal B.

J Virol. 2012 Feb;86(3):1789-801. doi: 10.1128/JVI.06003-11. Epub 2011 Nov 23.

26.

Heterosubtype neutralizing responses to influenza A (H5N1) viruses are mediated by antibodies to virus haemagglutinin.

Garcia JM, Pepin S, Lagarde N, Ma ES, Vogel FR, Chan KH, Chiu SS, Peiris JS.

PLoS One. 2009 Nov 20;4(11):e7918. doi: 10.1371/journal.pone.0007918.

27.

Optimization and evaluation of an influenza A (H5) pseudotyped lentiviral particle-based serological assay.

Garcia JM, Lagarde N, Ma ES, de Jong MD, Peiris JS.

J Clin Virol. 2010 Jan;47(1):29-33. doi: 10.1016/j.jcv.2009.10.009. Epub 2009 Nov 7.

PMID:
19897409
28.

Comparison of dysplasia profiles in stimulated ovaries and in those with a genetic risk for ovarian cancer.

Dauplat J, Chene G, Pomel C, Dauplat MM, Le Bouëdec G, Mishellany F, Lagarde N, Bignon YJ, Jaffeux P, Aublet-Cuvelier B, Dechelotte P, Pouly JL, Penault-Llorca F.

Eur J Cancer. 2009 Nov;45(17):2977-83. doi: 10.1016/j.ejca.2009.06.012. Epub 2009 Oct 12.

PMID:
19822418
29.

Ki67 expression and docetaxel efficacy in patients with estrogen receptor-positive breast cancer.

Penault-Llorca F, André F, Sagan C, Lacroix-Triki M, Denoux Y, Verriele V, Jacquemier J, Baranzelli MC, Bibeau F, Antoine M, Lagarde N, Martin AL, Asselain B, Roché H.

J Clin Oncol. 2009 Jun 10;27(17):2809-15. doi: 10.1200/JCO.2008.18.2808. Epub 2009 Apr 20.

PMID:
19380452
30.
31.

Evolution of CFTR protein distribution in lung tissue from normal and CF human fetuses.

Marcorelles P, Montier T, Gillet D, Lagarde N, Ferec C.

Pediatr Pulmonol. 2007 Nov;42(11):1032-40.

PMID:
17902144
32.

Hemagglutinin pseudotyped lentiviral particles: characterization of a new method for avian H5N1 influenza sero-diagnosis.

Nefkens I, Garcia JM, Ling CS, Lagarde N, Nicholls J, Tang DJ, Peiris M, Buchy P, Altmeyer R.

J Clin Virol. 2007 May;39(1):27-33. Epub 2007 Apr 3.

PMID:
17409017
33.

[Treatment of squamous cell carcinoma of the pancreas with gemcitabine].

Bideau K, Metges JP, Bayle S, André M, Robaszkiewicz M, Lagarde N, Labat JP.

Gastroenterol Clin Biol. 2006 Oct;30(10):1217-20. French.

34.

Cerebellar-pulmonary embolism, cause of death in the newborn.

Clement R, Bresson C, Marcorelles P, Rodat O, Lagarde N.

J Clin Forensic Med. 2006 Aug-Nov;13(6-8):361-5. Epub 2006 Oct 5. Review.

PMID:
17027323
35.
36.

Fetal aqueductal glioneuronal hamartoma: a clinicopathological and physiopathological study of three cases.

Marcorelles P, Fallet-Bianco C, Oury JF, van Wallenghem E, Parent P, Labadie G, Lagarde N, Laquerrière A.

Clin Neuropathol. 2005 Jul-Aug;24(4):155-62.

PMID:
16033131
37.

Diffuse EGFR staining is associated with reduced overall survival in locally advanced oesophageal squamous cell cancer.

Gibault L, Metges JP, Conan-Charlet V, Lozac'h P, Robaszkiewicz M, Bessaguet C, Lagarde N, Volant A.

Br J Cancer. 2005 Jul 11;93(1):107-15.

38.

An incidental zygomycetes-like placental infection.

Marcorelles P, Lagarde N, Romain C, Ibara AS, Duclos AS, Le Flohic AM.

Eur J Obstet Gynecol Reprod Biol. 2005 Mar 1;119(1):127-8. No abstract available.

PMID:
15734099
39.

Diagnosis and outcome of complete hydatidiform mole coexisting with a live twin fetus.

Marcorelles P, Audrezet MP, Le Bris MJ, Laurent Y, Chabaud JJ, Ferec C, de Braekeleer M, Collet M, Lagarde N.

Eur J Obstet Gynecol Reprod Biol. 2005 Jan 10;118(1):21-7.

PMID:
15596267
40.

Recombinant humanised anti-HER2/neu antibody (Herceptin) induces cellular death of glioblastomas.

Mineo JF, Bordron A, Quintin-Roué I, Loisel S, Ster KL, Buhé V, Lagarde N, Berthou C.

Br J Cancer. 2004 Sep 13;91(6):1195-9.

41.

Factors associated with liver steatosis and fibrosis in chronic hepatitis C patients.

Cholet F, Nousbaum JB, Richecoeur M, Oger E, Cauvin JM, Lagarde N, Robaszkiewicz M, Gouérou H.

Gastroenterol Clin Biol. 2004 Mar;28(3):272-8.

42.

Systemic effects on bone healing of a new hyaluronic acid-like bacterial exopolysaccharide.

Zanchetta P, Lagarde N, Guezennec J.

Calcif Tissue Int. 2003 Sep;73(3):232-6.

PMID:
14667135
43.

[A congenital renal tumor].

Marcorelles P, Germouty I, Redon JY, Lagarde N.

Ann Pathol. 2003 Apr;23(2):179-80. French. No abstract available.

PMID:
12843977
44.

A new bone-healing material: a hyaluronic acid-like bacterial exopolysaccharide.

Zanchetta P, Lagarde N, Guezennec J.

Calcif Tissue Int. 2003 Jan;72(1):74-9. Epub 2002 Oct 10.

PMID:
12370797
45.

[Sudden death of a two-year-old boy with influenza A virus infection: study of an autopsy case].

Marcorelles P, Freymuth F, Rambaud C, Gardach C, Legrand-Quillien MC, Lagarde N.

Arch Pediatr. 2002 Jan;9(1):41-4. French.

PMID:
11865549
46.

Giant axonal neuropathy locus refinement to a < 590 kb critical interval.

Cavalier L, BenHamida C, Amouri R, Belal S, Bomont P, Lagarde N, Gressin L, Callen D, Demir E, Topaloglu H, Landrieu P, Ioos C, Hamida MB, Koenig M, Hentati F.

Eur J Hum Genet. 2000 Jul;8(7):527-34.

47.

[Interest in placental apposition as an epidemiological marker for malaria].

Testa J, Awodabon J, Lagarde N, Olivier T, Delmont J.

Bull Soc Pathol Exot. 1991;84(5 Pt 5):473-9. Review. French.

PMID:
1819396
48.

[Plasmodial indices and malarial placentopathy in 299 parturients in Central Africa].

Testa J, Awodabon J, Lagarde N, Olivier T, Delmont J.

Med Trop (Mars). 1990 Jan-Mar;50(1):85-90. French.

PMID:
2195287
49.

Lympho-cutaneous Kaposi's sarcoma in an African pediatric AIDS case.

Bouquety JC, Siopathis MR, Ravisse PR, Lagarde N, Georges-Courbot MC, Georges AJ.

Am J Trop Med Hyg. 1989 Mar;40(3):323-5.

PMID:
2929857
50.

[Preliminary study of stages of human meiosis in spermatocytes and ovocytes (author's transl)].

Geneix A, Lécher P, Jaffray JY, Lagarde N, Hermabessière J.

Hum Genet. 1980;53(3):327-33. French.

PMID:
7372337

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