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Best matches for Laganière J[au]:

Marker-free coselection for CRISPR-driven genome editing in human cells. Agudelo D et al. Nat Methods. (2017)

Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease. Zeitler B et al. Nat Med. (2019)

Unraveling the effects of an oxygen shock on cord blood units. Néron S et al. Blood Cells Mol Dis. (2018)

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Items: 39


Allele-selective transcriptional repression of mutant HTT for the treatment of Huntington's disease.

Zeitler B, Froelich S, Marlen K, Shivak DA, Yu Q, Li D, Pearl JR, Miller JC, Zhang L, Paschon DE, Hinkley SJ, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone JM, Nguyen HB, Qiao G, Ataei Y, Mendel MC, Amora R, Surosky R, Laganiere J, Vu BJ, Narayanan A, Sedaghat Y, Tillack K, Thiede C, Gärtner A, Kwak S, Bard J, Mrzljak L, Park L, Heikkinen T, Lehtimäki KK, Svedberg MM, Häggkvist J, Tari L, Tóth M, Varrone A, Halldin C, Kudwa AE, Ramboz S, Day M, Kondapalli J, Surmeier DJ, Urnov FD, Gregory PD, Rebar EJ, Muñoz-Sanjuán I, Zhang HS.

Nat Med. 2019 Jul;25(7):1131-1142. doi: 10.1038/s41591-019-0478-3. Epub 2019 Jul 1.


Valproic acid is protective in cellular and worm models of oculopharyngeal muscular dystrophy.

Abu-Baker A, Parker A, Ramalingam S, Laganiere J, Brais B, Neri C, Dion P, Rouleau G.

Neurology. 2018 Aug 7;91(6):e551-e561. doi: 10.1212/WNL.0000000000005942. Epub 2018 Jul 13.


Unraveling the effects of an oxygen shock on cord blood units.

Néron S, Fournier D, Cloutier M, Laganière J, Thibault L, Simard C.

Blood Cells Mol Dis. 2018 Sep;72:17-18. doi: 10.1016/j.bcmd.2018.06.002. Epub 2018 Jun 20. No abstract available.


Marker-free coselection for CRISPR-driven genome editing in human cells.

Agudelo D, Duringer A, Bozoyan L, Huard CC, Carter S, Loehr J, Synodinou D, Drouin M, Salsman J, Dellaire G, Laganière J, Doyon Y.

Nat Methods. 2017 Jun;14(6):615-620. doi: 10.1038/nmeth.4265. Epub 2017 Apr 17.


KCC3 axonopathy: neuropathological features in the central and peripheral nervous system.

Auer RN, Laganière JL, Robitaille YO, Richardson J, Dion PA, Rouleau GA, Shekarabi M.

Mod Pathol. 2016 Sep;29(9):962-76. doi: 10.1038/modpathol.2016.90. Epub 2016 May 27.


Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition.

Kahle KT, Schmouth JF, Lavastre V, Latremoliere A, Zhang J, Andrews N, Omura T, Laganière J, Rochefort D, Hince P, Castonguay G, Gaudet R, Mapplebeck JC, Sotocinal SG, Duan J, Ward C, Khanna AR, Mogil JS, Dion PA, Woolf CJ, Inquimbert P, Rouleau GA.

Sci Signal. 2016 Mar 29;9(421):ra32. doi: 10.1126/scisignal.aad0163.


LRRK2 mutations cause mitochondrial DNA damage in iPSC-derived neural cells from Parkinson's disease patients: reversal by gene correction.

Sanders LH, Laganière J, Cooper O, Mak SK, Vu BJ, Huang YA, Paschon DE, Vangipuram M, Sundararajan R, Urnov FD, Langston JW, Gregory PD, Zhang HS, Greenamyre JT, Isacson O, Schüle B.

Neurobiol Dis. 2014 Feb;62:381-6. doi: 10.1016/j.nbd.2013.10.013. Epub 2013 Oct 19.


Lithium chloride attenuates cell death in oculopharyngeal muscular dystrophy by perturbing Wnt/β-catenin pathway.

Abu-Baker A, Laganiere J, Gaudet R, Rochefort D, Brais B, Neri C, Dion PA, Rouleau GA.

Cell Death Dis. 2013 Oct 3;4:e821. doi: 10.1038/cddis.2013.342.


Potassium-chloride cotransporter 3 interacts with Vav2 to synchronize the cell volume decrease response with cell protrusion dynamics.

Salin-Cantegrel A, Shekarabi M, Rasheed S, Charron FM, Laganière J, Gaudet R, Dion PA, Lapointe JY, Rouleau GA.

PLoS One. 2013 May 28;8(5):e65294. doi: 10.1371/journal.pone.0065294. Print 2013.


Comparative analysis of the expression profile of Wnk1 and Wnk1/Hsn2 splice variants in developing and adult mouse tissues.

Shekarabi M, Lafrenière RG, Gaudet R, Laganière J, Marcinkiewicz MM, Dion PA, Rouleau GA.

PLoS One. 2013;8(2):e57807. doi: 10.1371/journal.pone.0057807. Epub 2013 Feb 25.


Loss of neuronal potassium/chloride cotransporter 3 (KCC3) is responsible for the degenerative phenotype in a conditional mouse model of hereditary motor and sensory neuropathy associated with agenesis of the corpus callosum.

Shekarabi M, Moldrich RX, Rasheed S, Salin-Cantegrel A, Laganière J, Rochefort D, Hince P, Huot K, Gaudet R, Kurniawan N, Sotocinal SG, Ritchie J, Dion PA, Mogil JS, Richards LJ, Rouleau GA.

J Neurosci. 2012 Mar 14;32(11):3865-76. doi: 10.1523/JNEUROSCI.3679-11.2012.


Expanded ATXN3 frameshifting events are toxic in Drosophila and mammalian neuron models.

Stochmanski SJ, Therrien M, Laganière J, Rochefort D, Laurent S, Karemera L, Gaudet R, Vyboh K, Van Meyel DJ, Di Cristo G, Dion PA, Gaspar C, Rouleau GA.

Hum Mol Genet. 2012 May 15;21(10):2211-8. doi: 10.1093/hmg/dds036. Epub 2012 Feb 14.


Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.

Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, Urnov FD, Rebar EJ, Gregory PD, Zhang HS, Jaenisch R.

Cell. 2011 Jul 22;146(2):318-31. doi: 10.1016/j.cell.2011.06.019. Epub 2011 Jul 14. Erratum in: Cell. 2011 Aug 19;146(4):659.


Transit defect of potassium-chloride Co-transporter 3 is a major pathogenic mechanism in hereditary motor and sensory neuropathy with agenesis of the corpus callosum.

Salin-Cantegrel A, Rivière JB, Shekarabi M, Rasheed S, Dacal S, Laganière J, Gaudet R, Rochefort D, Lesca G, Gaspar C, Dion PA, Lapointe JY, Rouleau GA.

J Biol Chem. 2011 Aug 12;286(32):28456-65. doi: 10.1074/jbc.M111.226894. Epub 2011 May 31.


An engineered zinc finger protein activator of the endogenous glial cell line-derived neurotrophic factor gene provides functional neuroprotection in a rat model of Parkinson's disease.

Laganiere J, Kells AP, Lai JT, Guschin D, Paschon DE, Meng X, Fong LK, Yu Q, Rebar EJ, Gregory PD, Bankiewicz KS, Forsayeth J, Zhang HS.

J Neurosci. 2010 Dec 8;30(49):16469-74. doi: 10.1523/JNEUROSCI.2440-10.2010.


Cellular expression of the K+-Cl- cotransporter KCC3 in the central nervous system of mouse.

Shekarabi M, Salin-Cantegrel A, Laganière J, Gaudet R, Dion P, Rouleau GA.

Brain Res. 2011 Feb 16;1374:15-26. doi: 10.1016/j.brainres.2010.12.010. Epub 2010 Dec 11.


Genome-wide identification of direct target genes implicates estrogen-related receptor alpha as a determinant of breast cancer heterogeneity.

Deblois G, Hall JA, Perry MC, Laganière J, Ghahremani M, Park M, Hallett M, Giguère V.

Cancer Res. 2009 Aug 1;69(15):6149-57. doi: 10.1158/0008-5472.CAN-09-1251. Epub 2009 Jul 21.


HMSN/ACC truncation mutations disrupt brain-type creatine kinase-dependant activation of K+/Cl- co-transporter 3.

Salin-Cantegrel A, Shekarabi M, Holbert S, Dion P, Rochefort D, Laganière J, Dacal S, Hince P, Karemera L, Gaspar C, Lapointe JY, Rouleau GA.

Hum Mol Genet. 2008 Sep 1;17(17):2703-11. doi: 10.1093/hmg/ddn172. Epub 2008 Jun 19.


Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II.

Shekarabi M, Girard N, Rivière JB, Dion P, Houle M, Toulouse A, Lafrenière RG, Vercauteren F, Hince P, Laganiere J, Rochefort D, Faivre L, Samuels M, Rouleau GA.

J Clin Invest. 2008 Jul;118(7):2496-505. doi: 10.1172/JCI34088.


Nuclear receptor ERR alpha and coactivator PGC-1 beta are effectors of IFN-gamma-induced host defense.

Sonoda J, Laganière J, Mehl IR, Barish GD, Chong LW, Li X, Scheffler IE, Mock DC, Bataille AR, Robert F, Lee CH, Giguère V, Evans RM.

Genes Dev. 2007 Aug 1;21(15):1909-20.


Soluble expanded PABPN1 promotes cell death in oculopharyngeal muscular dystrophy.

Messaed C, Dion PA, Abu-Baker A, Rochefort D, Laganiere J, Brais B, Rouleau GA.

Neurobiol Dis. 2007 Jun;26(3):546-57. Epub 2007 Feb 15.


[Decoding the mode of action of the estrogen receptor through functional genomics].

Laganière J, Giguère V.

Bull Cancer. 2006 Sep;93(9):883-7. French.


Genome-wide computational prediction of transcriptional regulatory modules reveals new insights into human gene expression.

Blanchette M, Bataille AR, Chen X, Poitras C, Laganière J, Lefèbvre C, Deblois G, Giguère V, Ferretti V, Bergeron D, Coulombe B, Robert F.

Genome Res. 2006 May;16(5):656-68. Epub 2006 Apr 10.


From the Cover: Location analysis of estrogen receptor alpha target promoters reveals that FOXA1 defines a domain of the estrogen response.

Laganière J, Deblois G, Lefebvre C, Bataille AR, Robert F, Giguère V.

Proc Natl Acad Sci U S A. 2005 Aug 16;102(33):11651-6. Epub 2005 Aug 8.


Transcriptional regulation of dehydroepiandrosterone sulfotransferase (SULT2A1) by estrogen-related receptor alpha.

Seely J, Amigh KS, Suzuki T, Mayhew B, Sasano H, Giguere V, Laganière J, Carr BR, Rainey WE.

Endocrinology. 2005 Aug;146(8):3605-13. Epub 2005 May 5.


Functional genomics identifies a mechanism for estrogen activation of the retinoic acid receptor alpha1 gene in breast cancer cells.

Laganière J, Deblois G, Giguère V.

Mol Endocrinol. 2005 Jun;19(6):1584-92. Epub 2005 Apr 14.


Transgenic expression of an expanded (GCG)13 repeat PABPN1 leads to weakness and coordination defects in mice.

Dion P, Shanmugam V, Gaspar C, Messaed C, Meijer I, Toulouse A, Laganiere J, Roussel J, Rochefort D, Laganiere S, Allen C, Karpati G, Bouchard JP, Brais B, Rouleau GA.

Neurobiol Dis. 2005 Apr;18(3):528-36.


Endothelium properties of a tissue-engineered blood vessel for small-diameter vascular reconstruction.

Rémy-Zolghadri M, Laganière J, Oligny JF, Germain L, Auger FA.

J Vasc Surg. 2004 Mar;39(3):613-20.


Nuclear receptor target gene discovery using high-throughput chromatin immunoprecipitation.

Laganière J, Deblois G, Giguère V.

Methods Enzymol. 2003;364:339-50. No abstract available.


HnRNP A1 and A/B interaction with PABPN1 in oculopharyngeal muscular dystrophy.

Fan X, Messaed C, Dion P, Laganiere J, Brais B, Karpati G, Rouleau GA.

Can J Neurol Sci. 2003 Aug;30(3):244-51.


Involvement of the ubiquitin-proteasome pathway and molecular chaperones in oculopharyngeal muscular dystrophy.

Abu-Baker A, Messaed C, Laganiere J, Gaspar C, Brais B, Rouleau GA.

Hum Mol Genet. 2003 Oct 15;12(20):2609-23. Epub 2003 Aug 27.


Oligomerization of polyalanine expanded PABPN1 facilitates nuclear protein aggregation that is associated with cell death.

Fan X, Dion P, Laganiere J, Brais B, Rouleau GA.

Hum Mol Genet. 2001 Oct 1;10(21):2341-51.


Schwannomin isoform-1 interacts with syntenin via PDZ domains.

Jannatipour M, Dion P, Khan S, Jindal H, Fan X, Laganière J, Chishti AH, Rouleau GA.

J Biol Chem. 2001 Aug 31;276(35):33093-100. Epub 2001 Jun 29.


Neuron-specific expression of mutant superoxide dismutase 1 in transgenic mice does not lead to motor impairment.

Pramatarova A, Laganière J, Roussel J, Brisebois K, Rouleau GA.

J Neurosci. 2001 May 15;21(10):3369-74.


PABP2 polyalanine tract expansion causes intranuclear inclusions in oculopharyngeal muscular dystrophy.

Shanmugam V, Dion P, Rochefort D, Laganière J, Brais B, Rouleau GA.

Ann Neurol. 2000 Nov;48(5):798-802.


CAG tract of MJD-1 may be prone to frameshifts causing polyalanine accumulation.

Gaspar C, Jannatipour M, Dion P, Laganière J, Sequeiros J, Brais B, Rouleau GA.

Hum Mol Genet. 2000 Aug 12;9(13):1957-66.


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