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Items: 6


Distal and proximal hypoxia response elements cooperate to regulate organ-specific erythropoietin gene expression.

Orlando IMC, Lafleur VN, Storti F, Spielmann P, Crowther L, Santambrogio S, Schödel J, Hoogewijs D, Mole DR, Wenger RH.

Haematologica. 2019 Dec 19. pii: haematol.2019.236406. doi: 10.3324/haematol.2019.236406. [Epub ahead of print]


Co-incidence of RCC-susceptibility polymorphisms with HIF cis-acting sequences supports a pathway tuning model of cancer.

Schmid V, Lafleur VN, Lombardi O, Li R, Salama R, Colli L, Choudhry H, Chanock S, Ratcliffe PJ, Mole DR.

Sci Rep. 2019 Dec 10;9(1):18768. doi: 10.1038/s41598-019-55098-7.


The prolyl isomerase Pin1 regulates hypoxia-inducible transcription factor (HIF) activity.

Jalouli M, Déry MA, Lafleur VN, Lamalice L, Zhou XZ, Lu KP, Richard DE.

Cell Signal. 2014 Aug;26(8):1649-56. doi: 10.1016/j.cellsig.2014.04.005. Epub 2014 Apr 12.


Transcriptional repression of hypoxia-inducible factor-1 (HIF-1) by the protein arginine methyltransferase PRMT1.

Lafleur VN, Richard S, Richard DE.

Mol Biol Cell. 2014 Mar;25(6):925-35. doi: 10.1091/mbc.E13-07-0423. Epub 2014 Jan 22.


The Werner syndrome gene product (WRN): a repressor of hypoxia-inducible factor-1 activity.

Labbé A, Lafleur VN, Patten DA, Robitaille GA, Garand C, Lamalice L, Lebel M, Richard DE.

Exp Cell Res. 2012 Aug 15;318(14):1620-32. doi: 10.1016/j.yexcr.2012.04.010. Epub 2012 May 31.


Hypoxia-inducible factor-1 activation in nonhypoxic conditions: the essential role of mitochondrial-derived reactive oxygen species.

Patten DA, Lafleur VN, Robitaille GA, Chan DA, Giaccia AJ, Richard DE.

Mol Biol Cell. 2010 Sep 15;21(18):3247-57. doi: 10.1091/mbc.E10-01-0025. Epub 2010 Jul 21.

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