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Items: 13

1.

Validation of bupropion hydroxylation as a selective marker of human cytochrome P450 2B6 catalytic activity.

Faucette SR, Hawke RL, Lecluyse EL, Shord SS, Yan B, Laethem RM, Lindley CM.

Drug Metab Dispos. 2000 Oct;28(10):1222-30.

PMID:
10997944
2.

A high throughput sphingomyelinase assay.

Hassler DF, Laethem RM, Smith GK.

Methods Enzymol. 2000;311:176-84. No abstract available.

PMID:
10563323
4.

Toward antibody-directed enzyme prodrug therapy with the T268G mutant of human carboxypeptidase A1 and novel in vivo stable prodrugs of methotrexate.

Smith GK, Banks S, Blumenkopf TA, Cory M, Humphreys J, Laethem RM, Miller J, Moxham CP, Mullin R, Ray PH, Walton LM, Wolfe LA 3rd.

J Biol Chem. 1997 Jun 20;272(25):15804-16.

5.

Expression and characterization of human pancreatic preprocarboxypeptidase A1 and preprocarboxypeptidase A2.

Laethem RM, Blumenkopf TA, Cory M, Elwell L, Moxham CP, Ray PH, Walton LM, Smith GK.

Arch Biochem Biophys. 1996 Aug 1;332(1):8-18.

PMID:
8806703
6.

Epoxidation of C18 unsaturated fatty acids by cytochromes P4502C2 and P4502CAA.

Laethem RM, Balazy M, Koop DR.

Drug Metab Dispos. 1996 Jun;24(6):664-8.

PMID:
8781783
7.

Stereoselective epoxidation of arachidonic acid by cytochrome P-450s 2CAA and 2C2.

Daikh BE, Laethem RM, Koop DR.

J Pharmacol Exp Ther. 1994 Jun;269(3):1130-5.

PMID:
8014857
8.

Epoxidation of arachidonic acid as an active-site probe of cytochrome P-450 2B isoforms.

Laethem RM, Halpert JR, Koop DR.

Biochim Biophys Acta. 1994 May 18;1206(1):42-8.

PMID:
7910485
9.

Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1.

Laethem RM, Balazy M, Falck JR, Laethem CL, Koop DR.

J Biol Chem. 1993 Jun 15;268(17):12912-8.

10.

Identification of rabbit cytochromes P450 2C1 and 2C2 as arachidonic acid epoxygenases.

Laethem RM, Koop DR.

Mol Pharmacol. 1992 Dec;42(6):958-63.

PMID:
1480136
11.

P-450-dependent arachidonic acid metabolism in rabbit olfactory microsomes.

Laethem RM, Laethem CL, Ding X, Koop DR.

J Pharmacol Exp Ther. 1992 Jul;262(1):433-8.

PMID:
1625211
12.
13.

Cytochrome P450 expression and metabolism in isolated rabbit renal epithelium.

Koop DR, Laethem RM, Goldner AL, Douglas JG.

Methods Enzymol. 1991;206:364-71. No abstract available.

PMID:
1784223

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