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Items: 1 to 50 of 112


The Forgotten Joint Score-12 as a valuable patient-reported outcome measure for patients after first-time patellar dislocation.

Ladurner A, Giesinger K, Zdravkovic V, Behrend H.

Knee. 2020 Jan 8. pii: S0968-0160(19)30315-1. doi: 10.1016/j.knee.2019.12.004. [Epub ahead of print]


Exploiting the Circadian Clock for Improved Cancer Therapy: Perspective From a Cell Biologist.

Kuo TT, Ladurner AG.

Front Genet. 2019 Dec 11;10:1210. doi: 10.3389/fgene.2019.01210. eCollection 2019. No abstract available.


The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions.

Murawska M, Schauer T, Matsuda A, Wilson MD, Pysik T, Wojcik F, Muir TW, Hiraoka Y, Straub T, Ladurner AG.

Mol Cell. 2019 Dec 3. pii: S1097-2765(19)30864-0. doi: 10.1016/j.molcel.2019.11.016. [Epub ahead of print]


Impact of natural products on the cholesterol transporter ABCA1.

Wang D, Hiebl V, Xu T, Ladurner A, Atanasov AG, Heiss EH, Dirsch VM.

J Ethnopharmacol. 2020 Mar 1;249:112444. doi: 10.1016/j.jep.2019.112444. Epub 2019 Dec 2. Review.


Decrease surgery time by using an alternative lateral parapatellar approach for tibia shaft fracture nailing.

Ladurner A, Acklin YP, Mueller TS, Sommer C.

Arch Orthop Trauma Surg. 2019 Jul;139(7):943-949. doi: 10.1007/s00402-019-03154-2. Epub 2019 Mar 7.


MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.

Kozlowski M, Corujo D, Hothorn M, Guberovic I, Mandemaker IK, Blessing C, Sporn J, Gutierrez-Triana A, Smith R, Portmann T, Treier M, Scheffzek K, Huet S, Timinszky G, Buschbeck M, Ladurner AG.

EMBO Rep. 2018 Oct;19(10). pii: e44445. doi: 10.15252/embr.201744445. Epub 2018 Sep 3.


Novel interactomics approach identifies ABCA1 as direct target of evodiamine, which increases macrophage cholesterol efflux.

Wang L, Eftekhari P, Schachner D, Ignatova ID, Palme V, Schilcher N, Ladurner A, Heiss EH, Stangl H, Dirsch VM, Atanasov AG.

Sci Rep. 2018 Jul 23;8(1):11061. doi: 10.1038/s41598-018-29281-1.


In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.

Kirchweger B, Kratz JM, Ladurner A, Grienke U, Langer T, Dirsch VM, Rollinger JM.

Front Chem. 2018 Jul 2;6:242. doi: 10.3389/fchem.2018.00242. eCollection 2018.


Vitamin C demand is increased after total knee arthroplasty: a double-blind placebo-controlled-randomized study.

Behrend H, Lengnick H, Zdravkovic V, Ladurner A, Rudin D, Erschbamer M, Joerger M, Kuster M.

Knee Surg Sports Traumatol Arthrosc. 2019 Apr;27(4):1182-1188. doi: 10.1007/s00167-018-5030-3. Epub 2018 Jun 28.


Blackburne-Peel ratio predicts patients' outcomes after total knee arthroplasty.

Behrend H, Graulich T, Gerlach R, Spross C, Ladurner A.

Knee Surg Sports Traumatol Arthrosc. 2019 May;27(5):1562-1569. doi: 10.1007/s00167-018-5016-1. Epub 2018 Jun 8.


6-Dihydroparadol, a Ginger Constituent, Enhances Cholesterol Efflux from THP-1-Derived Macrophages.

Wang D, Hiebl V, Ladurner A, Latkolik SL, Bucar F, Heiß EH, Dirsch VM, Atanasov AG.

Mol Nutr Food Res. 2018 May 26:e1800011. doi: 10.1002/mnfr.201800011. [Epub ahead of print]


Femoral Bone Restoration Patterns in Revision Total Hip Arthroplasty Using Distally Fixed Modular Tapered Titanium Stems and an Extended Trochanteric Osteotomy Approach.

Ladurner A, Zdravkovic V, Grob K.

J Arthroplasty. 2018 Jul;33(7):2210-2217. doi: 10.1016/j.arth.2018.02.065. Epub 2018 Feb 26.


Natural products as modulators of the nuclear receptors and metabolic sensors LXR, FXR and RXR.

Hiebl V, Ladurner A, Latkolik S, Dirsch VM.

Biotechnol Adv. 2018 Nov 1;36(6):1657-1698. doi: 10.1016/j.biotechadv.2018.03.003. Epub 2018 Mar 13. Review.


A Poly-ADP-Ribose Trigger Releases the Auto-Inhibition of a Chromatin Remodeling Oncogene.

Singh HR, Nardozza AP, Möller IR, Knobloch G, Kistemaker HAV, Hassler M, Harrer N, Blessing C, Eustermann S, Kotthoff C, Huet S, Mueller-Planitz F, Filippov DV, Timinszky G, Rand KD, Ladurner AG.

Mol Cell. 2017 Dec 7;68(5):860-871.e7. doi: 10.1016/j.molcel.2017.11.019.


Linked magnolol dimer as a selective PPARγ agonist - Structure-based rational design, synthesis, and bioactivity evaluation.

Dreier D, Latkolik S, Rycek L, Schnürch M, Dymáková A, Atanasov AG, Ladurner A, Heiss EH, Stuppner H, Schuster D, Mihovilovic MD, Dirsch VM.

Sci Rep. 2017 Oct 20;7(1):13002. doi: 10.1038/s41598-017-12628-5.


MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD+ consumption.

Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M.

Nat Struct Mol Biol. 2017 Nov;24(11):902-910. doi: 10.1038/nsmb.3481. Epub 2017 Oct 9.


The Dietary Constituent Falcarindiol Promotes Cholesterol Efflux from THP-1 Macrophages by Increasing ABCA1 Gene Transcription and Protein Stability.

Wang L, Palme V, Schilcher N, Ladurner A, Heiss EH, Stangl H, Bauer R, Dirsch VM, Atanasov AG.

Front Pharmacol. 2017 Sep 1;8:596. doi: 10.3389/fphar.2017.00596. eCollection 2017.


Assessment of anti-inflammatory properties of extracts from Honeysuckle (Lonicera sp. L., Caprifoliaceae) by ATR-FTIR spectroscopy.

Nikzad-Langerodi R, Ortmann S, Pferschy-Wenzig EM, Bochkov V, Zhao YM, Miao JH, Saukel J, Ladurner A, Heiss EH, Dirsch VM, Bauer R, Atanasov AG.

Talanta. 2017 Dec 1;175:264-272. doi: 10.1016/j.talanta.2017.07.045. Epub 2017 Jul 18.


Allspice and Clove As Source of Triterpene Acids Activating the G Protein-Coupled Bile Acid Receptor TGR5.

Ladurner A, Zehl M, Grienke U, Hofstadler C, Faur N, Pereira FC, Berry D, Dirsch VM, Rollinger JM.

Front Pharmacol. 2017 Jul 17;8:468. doi: 10.3389/fphar.2017.00468. eCollection 2017.


Erythrodiol, an Olive Oil Constituent, Increases the Half-Life of ABCA1 and Enhances Cholesterol Efflux from THP-1-Derived Macrophages.

Wang L, Wesemann S, Krenn L, Ladurner A, Heiss EH, Dirsch VM, Atanasov AG.

Front Pharmacol. 2017 Jun 13;8:375. doi: 10.3389/fphar.2017.00375. eCollection 2017.


Bilirubin Decreases Macrophage Cholesterol Efflux and ATP-Binding Cassette Transporter A1 Protein Expression.

Wang D, Tosevska A, Heiß EH, Ladurner A, Mölzer C, Wallner M, Bulmer A, Wagner KH, Dirsch VM, Atanasov AG.

J Am Heart Assoc. 2017 Apr 28;6(5). pii: e005520. doi: 10.1161/JAHA.117.005520.


Modified Extended Trochanteric Osteotomy for the Treatment of Vancouver B2/B3 Periprosthetic Fractures of the Femur.

Ladurner A, Zurmühle P, Zdravkovic V, Grob K.

J Arthroplasty. 2017 Aug;32(8):2487-2495. doi: 10.1016/j.arth.2017.02.079. Epub 2017 Mar 8.


Remodelers tap into nucleosome plasticity.

Singh HR, Murawska M, Ladurner AG.

Nat Struct Mol Biol. 2017 Apr 6;24(4):341-343. doi: 10.1038/nsmb.3394. No abstract available.


sNASP and ASF1A function through both competitive and compatible modes of histone binding.

Bowman A, Koide A, Goodman JS, Colling ME, Zinne D, Koide S, Ladurner AG.

Nucleic Acids Res. 2017 Jan 25;45(2):643-656. doi: 10.1093/nar/gkw892. Epub 2016 Oct 5.


Piperine inhibits ABCA1 degradation and promotes cholesterol efflux from THP-1-derived macrophages.

Wang L, Palme V, Rotter S, Schilcher N, Cukaj M, Wang D, Ladurner A, Heiss EH, Stangl H, Dirsch VM, Atanasov AG.

Mol Nutr Food Res. 2017 Apr;61(4). doi: 10.1002/mnfr.201500960. Epub 2016 Dec 23.


The poly(ADP-ribose)-dependent chromatin remodeler Alc1 induces local chromatin relaxation upon DNA damage.

Sellou H, Lebeaupin T, Chapuis C, Smith R, Hegele A, Singh HR, Kozlowski M, Bultmann S, Ladurner AG, Timinszky G, Huet S.

Mol Biol Cell. 2016 Dec 1;27(24):3791-3799. Epub 2016 Oct 12.


Nick Your DNA, Mark Your Chromatin.

Nardozza AP, Ladurner AG.

Mol Cell. 2016 Oct 6;64(1):7-9. doi: 10.1016/j.molcel.2016.09.023.


CENPs and Sweet Nucleosomes Face the FACT.

Murawska M, Ladurner AG.

Trends Biochem Sci. 2016 Sep;41(9):736-738. doi: 10.1016/j.tibs.2016.07.010. Epub 2016 Aug 4.


Synthesis and Macrodomain Binding of Mono-ADP-Ribosylated Peptides.

Kistemaker HA, Nardozza AP, Overkleeft HS, van der Marel GA, Ladurner AG, Filippov DV.

Angew Chem Int Ed Engl. 2016 Aug 26;55(36):10634-8. doi: 10.1002/anie.201604058. Epub 2016 Jul 28.


The Metabolic Impact on Histone Acetylation and Transcription in Ageing.

Peleg S, Feller C, Ladurner AG, Imhof A.

Trends Biochem Sci. 2016 Aug;41(8):700-711. doi: 10.1016/j.tibs.2016.05.008. Epub 2016 Jun 7. Review.


Leoligin, the Major Lignan from Edelweiss (Leontopodium nivale subsp. alpinum), Promotes Cholesterol Efflux from THP-1 Macrophages.

Wang L, Ladurner A, Latkolik S, Schwaiger S, Linder T, Hošek J, Palme V, Schilcher N, Polanský O, Heiss EH, Stangl H, Mihovilovic MD, Stuppner H, Dirsch VM, Atanasov AG.

J Nat Prod. 2016 Jun 24;79(6):1651-7. doi: 10.1021/acs.jnatprod.6b00227. Epub 2016 May 24.


The Histone Variant MacroH2A1.2 Is Necessary for the Activation of Muscle Enhancers and Recruitment of the Transcription Factor Pbx1.

Dell'Orso S, Wang AH, Shih HY, Saso K, Berghella L, Gutierrez-Cruz G, Ladurner AG, O'Shea JJ, Sartorelli V, Zare H.

Cell Rep. 2016 Feb 9;14(5):1156-1168. doi: 10.1016/j.celrep.2015.12.103. Epub 2016 Jan 28.


Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.

Peleg S, Feller C, Forne I, Schiller E, Sévin DC, Schauer T, Regnard C, Straub T, Prestel M, Klima C, Schmitt Nogueira M, Becker L, Klopstock T, Sauer U, Becker PB, Imhof A, Ladurner AG.

EMBO Rep. 2016 Mar;17(3):455-69. doi: 10.15252/embr.201541132. Epub 2016 Jan 18.


Silymarin Constituents Enhance ABCA1 Expression in THP-1 Macrophages.

Wang L, Rotter S, Ladurner A, Heiss EH, Oberlies NH, Dirsch VM, Atanasov AG.

Molecules. 2015 Dec 31;21(1):E55. doi: 10.3390/molecules21010055.


Triterpenoic Acids from Apple Pomace Enhance the Activity of the Endothelial Nitric Oxide Synthase (eNOS).

Waldbauer K, Seiringer G, Nguyen DL, Winkler J, Blaschke M, McKinnon R, Urban E, Ladurner A, Dirsch VM, Zehl M, Kopp B.

J Agric Food Chem. 2016 Jan 13;64(1):185-94. doi: 10.1021/acs.jafc.5b05061. Epub 2015 Dec 30.


The histone chaperone sNASP binds a conserved peptide motif within the globular core of histone H3 through its TPR repeats.

Bowman A, Lercher L, Singh HR, Zinne D, Timinszky G, Carlomagno T, Ladurner AG.

Nucleic Acids Res. 2016 Apr 20;44(7):3105-17. doi: 10.1093/nar/gkv1372. Epub 2015 Dec 15.


ATM, MacroH2A.1, and SASP: The Checks and Balances of Cellular Senescence.

Kozlowski M, Ladurner AG.

Mol Cell. 2015 Sep 3;59(5):713-5. doi: 10.1016/j.molcel.2015.08.010.


Corrigendum: The zinc-finger domains of PARP1 cooperate to recognize DNA strand breaks.

Ali AA, Timinszky G, Arribas-Bosacoma R, Kozlowski M, Hassa PO, Hassler M, Ladurner AG, Pearl LH, Oliver AW.

Nat Struct Mol Biol. 2015 Aug;22(8):645. doi: 10.1038/nsmb0815-645a. No abstract available.


Escherichia coli Nissle 1917 bacterial ghosts retain crucial surface properties and express chlamydial antigen: an imaging study of a delivery system for the ocular surface.

Montanaro J, Inic-Kanada A, Ladurner A, Stein E, Belij S, Bintner N, Schlacher S, Schuerer N, Mayr UB, Lubitz W, Leisch N, Barisani-Asenbauer T.

Drug Des Devel Ther. 2015 Jul 21;9:3741-54. doi: 10.2147/DDDT.S84370. eCollection 2015.


[Epileptic seizure-induced vertebral body fractures].

Ladurner A, Forster T, Külling FA.

Unfallchirurg. 2015 Dec;118(12):1067-9. doi: 10.1007/s00113-015-0040-9. German.


Designing Cell-Type-Specific Genome-wide Experiments.

Handley A, Schauer T, Ladurner AG, Margulies CE.

Mol Cell. 2015 May 21;58(4):621-31. doi: 10.1016/j.molcel.2015.04.024. Review.


PARP1 and CBP lose their footing in cancer.

Timinszky G, Ladurner AG.

Nat Struct Mol Biol. 2014 Nov;21(11):947-8. doi: 10.1038/nsmb.2913. No abstract available.


Impact of trans-resveratrol-sulfates and -glucuronides on endothelial nitric oxide synthase activity, nitric oxide release and intracellular reactive oxygen species.

Ladurner A, Schachner D, Schueller K, Pignitter M, Heiss EH, Somoza V, Dirsch VM.

Molecules. 2014 Oct 17;19(10):16724-36. doi: 10.3390/molecules191016724.


ACF takes the driver's seat.

Singh HR, Ladurner AG.

Mol Cell. 2014 Aug 7;55(3):345-6. doi: 10.1016/j.molcel.2014.07.014.


Catch me if you can: how the histone chaperone FACT capitalizes on nucleosome breathing.

Hondele M, Ladurner AG.

Nucleus. 2013 Nov-Dec;4(6):443-9. doi: 10.4161/nucl.27235. Epub 2013 Dec 5.


CAST-ChIP maps cell-type-specific chromatin states in the Drosophila central nervous system.

Schauer T, Schwalie PC, Handley A, Margulies CE, Flicek P, Ladurner AG.

Cell Rep. 2013 Oct 17;5(1):271-82. doi: 10.1016/j.celrep.2013.09.001. Epub 2013 Oct 3.


Honokiol: a non-adipogenic PPARγ agonist from nature.

Atanasov AG, Wang JN, Gu SP, Bu J, Kramer MP, Baumgartner L, Fakhrudin N, Ladurner A, Malainer C, Vuorinen A, Noha SM, Schwaiger S, Rollinger JM, Schuster D, Stuppner H, Dirsch VM, Heiss EH.

Biochim Biophys Acta. 2013 Oct;1830(10):4813-9. doi: 10.1016/j.bbagen.2013.06.021. Epub 2013 Jun 27.


Structures of Drosophila cryptochrome and mouse cryptochrome1 provide insight into circadian function.

Czarna A, Berndt A, Singh HR, Grudziecki A, Ladurner AG, Timinszky G, Kramer A, Wolf E.

Cell. 2013 Jun 6;153(6):1394-405. doi: 10.1016/j.cell.2013.05.011.


The recognition and removal of cellular poly(ADP-ribose) signals.

Barkauskaite E, Jankevicius G, Ladurner AG, Ahel I, Timinszky G.

FEBS J. 2013 Aug;280(15):3491-507. doi: 10.1111/febs.12358. Epub 2013 Jun 18. Review.


Structural basis of histone H2A-H2B recognition by the essential chaperone FACT.

Hondele M, Stuwe T, Hassler M, Halbach F, Bowman A, Zhang ET, Nijmeijer B, Kotthoff C, Rybin V, Amlacher S, Hurt E, Ladurner AG.

Nature. 2013 Jul 4;499(7456):111-4. doi: 10.1038/nature12242. Epub 2013 May 22.


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