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Items: 31

1.

Working with Hypoxia.

Bowler E, Ladomery MR.

Methods Mol Biol. 2019;1990:109-133. doi: 10.1007/978-1-4939-9463-2_10.

PMID:
31148067
2.

Investigating ROS, RNS, and H2S-Sensitive Signaling Proteins.

Williams E, Whiteman M, Wood ME, Wilson ID, Ladomery MR, Allainguillaume J, Teklic T, Lisjak M, Hancock JT.

Methods Mol Biol. 2019;1990:27-42. doi: 10.1007/978-1-4939-9463-2_3.

PMID:
31148060
3.

The Evolutionarily Conserved Cassette Exon 7b Drives ERG's Oncogenic Properties.

Jumbe SL, Porazinski SR, Oltean S, Mansell JP, Vahabi B, Wilson ID, Ladomery MR.

Transl Oncol. 2019 Jan;12(1):134-142. doi: 10.1016/j.tranon.2018.09.001. Epub 2018 Oct 5.

4.

The oncogenic transcription factor ERG represses the transcription of the tumour suppressor gene PTEN in prostate cancer cells.

Adamo P, Porazinski S, Rajatileka S, Jumbe S, Hagen R, Cheung MK, Wilson I, Ladomery MR.

Oncol Lett. 2017 Nov;14(5):5605-5610. doi: 10.3892/ol.2017.6841. Epub 2017 Aug 28.

5.

Residual ground-water levels of the neonicotinoid thiacloprid perturb chemosensing of Caenorhabditis elegans.

Hopewell H, Floyd KG, Burnell D, Hancock JT, Allainguillaume J, Ladomery MR, Wilson ID.

Ecotoxicology. 2017 Sep;26(7):981-990. doi: 10.1007/s10646-017-1826-z. Epub 2017 Jun 22.

6.

Insulin Receptor Isoform Variations in Prostate Cancer Cells.

Perks CM, Zielinska HA, Wang J, Jarrett C, Frankow A, Ladomery MR, Bahl A, Rhodes A, Oxley J, Holly JM.

Front Endocrinol (Lausanne). 2016 Sep 28;7:132. eCollection 2016.

7.

The oncogene ERG: a key factor in prostate cancer.

Adamo P, Ladomery MR.

Oncogene. 2016 Jan 28;35(4):403-14. doi: 10.1038/onc.2015.109. Epub 2015 Apr 27. Review.

PMID:
25915839
8.

Detection of thiol modifications by hydrogen sulfide.

Williams E, Pead S, Whiteman M, Wood ME, Wilson ID, Ladomery MR, Teklic T, Lisjak M, Hancock JT.

Methods Enzymol. 2015;555:233-51. doi: 10.1016/bs.mie.2014.11.026. Epub 2015 Jan 8.

PMID:
25747483
9.

Serine-arginine protein kinase 1 (SRPK1) inhibition as a potential novel targeted therapeutic strategy in prostate cancer.

Mavrou A, Brakspear K, Hamdollah-Zadeh M, Damodaran G, Babaei-Jadidi R, Oxley J, Gillatt DA, Ladomery MR, Harper SJ, Bates DO, Oltean S.

Oncogene. 2015 Aug 13;34(33):4311-9. doi: 10.1038/onc.2014.360. Epub 2014 Nov 10.

10.

Quantitative analysis of ERG expression and its splice isoforms in formalin-fixed, paraffin-embedded prostate cancer samples: association with seminal vesicle invasion and biochemical recurrence.

Hagen RM, Adamo P, Karamat S, Oxley J, Aning JJ, Gillatt D, Persad R, Ladomery MR, Rhodes A.

Am J Clin Pathol. 2014 Oct;142(4):533-40. doi: 10.1309/AJCPH88QHXARISUP.

PMID:
25239421
11.

Alternative splicing of TIA-1 in human colon cancer regulates VEGF isoform expression, angiogenesis, tumour growth and bevacizumab resistance.

Hamdollah Zadeh MA, Amin EM, Hoareau-Aveilla C, Domingo E, Symonds KE, Ye X, Heesom KJ, Salmon A, D'Silva O, Betteridge KB, Williams AC, Kerr DJ, Salmon AH, Oltean S, Midgley RS, Ladomery MR, Harper SJ, Varey AH, Bates DO.

Mol Oncol. 2015 Jan;9(1):167-78. doi: 10.1016/j.molonc.2014.07.017. Epub 2014 Aug 20.

12.
13.

Modulation of the antioxidant/pro-oxidant balance, cytotoxicity and antiviral actions of grape seed extracts.

Ignea C, DorobanĊ£u CM, Mintoff CP, Branza-Nichita N, Ladomery MR, Kefalas P, Chedea VS.

Food Chem. 2013 Dec 15;141(4):3967-76. doi: 10.1016/j.foodchem.2013.06.094. Epub 2013 Jun 29.

PMID:
23993573
14.

The relationship between the structure and biological actions of green tea catechins.

Braicu C, Ladomery MR, Chedea VS, Irimie A, Berindan-Neagoe I.

Food Chem. 2013 Dec 1;141(3):3282-9. doi: 10.1016/j.foodchem.2013.05.122. Epub 2013 Jun 4. Review.

PMID:
23871088
15.

A M-MLV reverse transcriptase with reduced RNaseH activity allows greater sensitivity of gene expression detection in formalin fixed and paraffin embedded prostate cancer samples.

Hagen RM, Rhodes A, Oxley J, Ladomery MR.

Exp Mol Pathol. 2013 Aug;95(1):98-104. doi: 10.1016/j.yexmp.2013.05.008. Epub 2013 Jun 2.

PMID:
23739432
16.

Epigallocatechin-3-gallate promotes apoptosis and expression of the caspase 9a splice variant in PC3 prostate cancer cells.

Hagen RM, Chedea VS, Mintoff CP, Bowler E, Morse HR, Ladomery MR.

Int J Oncol. 2013 Jul;43(1):194-200. doi: 10.3892/ijo.2013.1920. Epub 2013 Apr 24.

PMID:
23615977
17.

Role of splice variants in the metastatic progression of prostate cancer.

Hagen RM, Ladomery MR.

Biochem Soc Trans. 2012 Aug;40(4):870-4. doi: 10.1042/BST20120026. Review.

PMID:
22817750
18.

SRPK1 inhibition in vivo: modulation of VEGF splicing and potential treatment for multiple diseases.

Oltean S, Gammons M, Hulse R, Hamdollah-Zadeh M, Mavrou A, Donaldson L, Salmon AH, Harper SJ, Ladomery MR, Bates DO.

Biochem Soc Trans. 2012 Aug;40(4):831-5. doi: 10.1042/BST20120051. Review.

PMID:
22817743
19.

WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing.

Amin EM, Oltean S, Hua J, Gammons MV, Hamdollah-Zadeh M, Welsh GI, Cheung MK, Ni L, Kase S, Rennel ES, Symonds KE, Nowak DG, Royer-Pokora B, Saleem MA, Hagiwara M, Schumacher VA, Harper SJ, Hinton DR, Bates DO, Ladomery MR.

Cancer Cell. 2011 Dec 13;20(6):768-80. doi: 10.1016/j.ccr.2011.10.016.

20.

MicroRNAs: their discovery, biogenesis, function and potential use as biomarkers in non-invasive prenatal diagnostics.

Ladomery MR, Maddocks DG, Wilson ID.

Int J Mol Epidemiol Genet. 2011 Aug 30;2(3):253-60. Epub 2011 Aug 3.

21.

Kinetic behaviour of WT 1's zinc finger domain in binding to the alpha-actinin-1 mRNA.

Nurmemmedov E, Yengo RK, Ladomery MR, Thunnissen MM.

Arch Biochem Biophys. 2010 May;497(1-2):21-7. doi: 10.1016/j.abb.2010.02.013. Epub 2010 Mar 1.

PMID:
20193655
22.

Regulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesis.

Nowak DG, Amin EM, Rennel ES, Hoareau-Aveilla C, Gammons M, Damodoran G, Hagiwara M, Harper SJ, Woolard J, Ladomery MR, Bates DO.

J Biol Chem. 2010 Feb 19;285(8):5532-40. doi: 10.1074/jbc.M109.074930. Epub 2009 Nov 11.

23.

Expression of pro- and anti-angiogenic isoforms of VEGF is differentially regulated by splicing and growth factors.

Nowak DG, Woolard J, Amin EM, Konopatskaya O, Saleem MA, Churchill AJ, Ladomery MR, Harper SJ, Bates DO.

J Cell Sci. 2008 Oct 15;121(Pt 20):3487-95. doi: 10.1242/jcs.016410.

24.

RAP55: insights into an evolutionarily conserved protein family.

Marnef A, Sommerville J, Ladomery MR.

Int J Biochem Cell Biol. 2009 May;41(5):977-81. doi: 10.1016/j.biocel.2008.06.015. Epub 2008 Aug 3. Review.

PMID:
18723115
25.

New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes.

Morrison AA, Viney RL, Saleem MA, Ladomery MR.

Am J Physiol Renal Physiol. 2008 Jul;295(1):F12-7. doi: 10.1152/ajprenal.00597.2007. Epub 2008 Apr 2. Review.

26.

The post-transcriptional roles of WT1, a multifunctional zinc-finger protein.

Morrison AA, Viney RL, Ladomery MR.

Biochim Biophys Acta. 2008 Jan;1785(1):55-62. Epub 2007 Oct 14. Review.

PMID:
17980713
27.

A proteomic investigation of glomerular podocytes from a Denys-Drash syndrome patient with a mutation in the Wilms tumour suppressor gene WT1.

Viney RL, Morrison AA, van den Heuvel LP, Ni L, Mathieson PW, Saleem MA, Ladomery MR.

Proteomics. 2007 Mar;7(5):804-15.

PMID:
17295355
28.

The Wilms tumour suppressor protein WT1 (+KTS isoform) binds alpha-actinin 1 mRNA via its zinc-finger domain.

Morrison AA, Venables JP, Dellaire G, Ladomery MR.

Biochem Cell Biol. 2006 Oct;84(5):789-98.

PMID:
17167543
29.

Alternative splicing in angiogenesis: the vascular endothelial growth factor paradigm.

Ladomery MR, Harper SJ, Bates DO.

Cancer Lett. 2007 May 8;249(2):133-42. Epub 2006 Oct 5. Review.

PMID:
17027147
30.

Presence of WT1 in nuclear messenger RNP particles in the human acute myeloid leukemia cell lines HL60 and K562.

Morrison AA, Ladomery MR.

Cancer Lett. 2006 Nov 28;244(1):136-41. Epub 2006 Feb 7.

PMID:
16457949
31.

Presence of WT1, the Wilm's tumor suppressor gene product, in nuclear poly(A)(+) ribonucleoprotein.

Ladomery MR, Slight J, Mc Ghee S, Hastie ND.

J Biol Chem. 1999 Dec 17;274(51):36520-6.

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