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A novel restorative pulmonary valved conduit in a chronic sheep model: Mid-term hemodynamic function and histologic assessment.

Bennink G, Torii S, Brugmans M, Cox M, Svanidze O, Ladich E, Carrel T, Virmani R.

J Thorac Cardiovasc Surg. 2018 Jun;155(6):2591-2601.e3. doi: 10.1016/j.jtcvs.2017.12.046. Epub 2017 Dec 21.


Community-based statins and advanced carotid plaque: Role of CD163 positive macrophages in lipoprotein-associated phospholipase A2 activity in atherosclerotic plaque.

Otsuka F, Zhao X, Trout HH, Qiao Y, Wasserman BA, Nakano M, Macphee CH, Brandt M, Krug-Gourley S, Guo L, Ladich ER, Cheng Q, Davis HR, Finn AV, Virmani R, Kolodgie FD.

Atherosclerosis. 2017 Dec;267:78-89. doi: 10.1016/j.atherosclerosis.2017.10.014. Epub 2017 Oct 14.


Chemical sympathetic denervation: promising, but important distinctions between agents and methods.

Bertog S, Vega F, Ghazarossian V, Pathak A, Vaskelyte L, Sievert H, Ladich E, Yahagi K, Virmani R.

EuroIntervention. 2017 Oct 13;13(9):e1131-e1132. doi: 10.4244/EIJ-D-16-01000R. No abstract available.


Pathology of self-expanding transcatheter aortic valves: Findings from the CoreValve US pivotal trials.

Yahagi K, Torii S, Ladich E, Kutys R, Romero ME, Mori H, Kolodgie FD, Popma JJ, Virmani R, Finn AV.

Catheter Cardiovasc Interv. 2018 Apr 1;91(5):947-955. doi: 10.1002/ccd.27314. Epub 2017 Sep 12.


Pathology of balloon-expandable transcatheter aortic valves.

Yahagi K, Ladich E, Kutys R, Mori H, Svensson LG, Mack MJ, Herrmann HC, Smith CR, Leon MB, Virmani R, Finn AV.

Catheter Cardiovasc Interv. 2017 Nov 15;90(6):1048-1057. doi: 10.1002/ccd.27160. Epub 2017 Jun 1.


Radiosurgical Ablation of the Renal Nerve in a Porcine Model: A Minimally Invasive Therapeutic Approach to Treat Refractory Hypertension.

Bhatt N, Long SA, Gardner EA, Tay J, Ladich E, Chamberlain D, Fogarty TJ, Maguire PJ.

Cureus. 2017 Feb 26;9(2):e1055. doi: 10.7759/cureus.1055.


Treatment of Burn and Surgical Wounds With Recombinant Human Tropoelastin Produces New Elastin Fibers in Scars.

Xie H, Lucchesi L, Zheng B, Ladich E, Pineda T, Merten R, Gregory C, Rutten M, Gregory K.

J Burn Care Res. 2017 Sep/Oct;38(5):e859-e867. doi: 10.1097/BCR.0000000000000507.


Pathology of Chronic Total Occlusion in Bare-Metal Versus Drug-Eluting Stents: Implications for Revascularization.

Mori H, Lutter C, Yahagi K, Harari E, Kutys R, Fowler DR, Ladich E, Joner M, Virmani R, Finn AV.

JACC Cardiovasc Interv. 2017 Feb 27;10(4):367-378. doi: 10.1016/j.jcin.2016.11.005. Epub 2017 Feb 1.


Relationship between Serum Inflammatory Biomarkers and Thrombus Characteristics in Patients with ST Segment Elevation Myocardial Infarction.

Niccoli G, Menozzi A, Capodanno D, Trani C, Sirbu V, Fineschi M, Zara C, Crea F, Trabattoni D, Saia F, Ladich E, Biondi Zoccai G, Attizzani G, Guagliumi G.

Cardiology. 2017;137(1):27-35. doi: 10.1159/000452705. Epub 2016 Dec 17.


Histological Findings and Predictors of Cerebral Debris From Transcatheter Aortic Valve Replacement: The ALSTER Experience.

Schmidt T, Akdag O, Wohlmuth P, Thielsen T, Schewel D, Schewel J, Alessandrini H, Kreidel F, Bader R, Romero M, Ladich E, Virmani R, Schäfer U, Kuck KH, Frerker C.

J Am Heart Assoc. 2016 Nov 10;5(11). pii: e004399.


Randomised, blinded and controlled comparative study of chemical and radiofrequency-based renal denervation in a porcine model.

Bertog S, Fischel TA, Vega F, Ghazarossian V, Pathak A, Vaskelyte L, Kent D, Sievert H, Ladich E, Yahagi K, Virmani R.

EuroIntervention. 2017 Feb 3;12(15):e1898-e1906. doi: 10.4244/EIJ-D-16-00206.


Histopathological Differential Diagnosis of Optical Coherence Tomographic Image Interpretation After Stenting.

Lutter C, Mori H, Yahagi K, Ladich E, Joner M, Kutys R, Fowler D, Romero M, Narula J, Virmani R, Finn AV.

JACC Cardiovasc Interv. 2016 Dec 26;9(24):2511-2523. doi: 10.1016/j.jcin.2016.09.016. Epub 2016 Nov 23.


Rationale of cerebral protection devices in left atrial appendage occlusion.

Meincke F, Spangenberg T, Kreidel F, Frerker C, Virmani R, Ladich E, Kuck KH, Ghanem A.

Catheter Cardiovasc Interv. 2017 Jan;89(1):154-158. doi: 10.1002/ccd.26677. Epub 2016 Oct 20.


Comparison of Particulate Embolization after Femoral Artery Treatment with IN.PACT Admiral versus Lutonix 035 Paclitaxel-Coated Balloons in Healthy Swine.

Kolodgie FD, Pacheco E, Yahagi K, Mori H, Ladich E, Virmani R.

J Vasc Interv Radiol. 2016 Nov;27(11):1676-1685.e2. doi: 10.1016/j.jvir.2016.06.036. Epub 2016 Sep 15.


Vascular diseases: aortitis, aortic aneurysms, and vascular calcification.

Ladich E, Yahagi K, Romero ME, Virmani R.

Cardiovasc Pathol. 2016 Sep-Oct;25(5):432-41. doi: 10.1016/j.carpath.2016.07.002. Epub 2016 Jul 14. Review.


Histology of debris captured by a cerebral protection system during transcatheter valve-in-valve implantation.

Schmidt T, Schlüter M, Alessandrini H, Akdag O, Schewel D, Schewel J, Thielsen T, Kreidel F, Bader R, Romero M, Ladich E, Virmani R, Schäfer U, Kuck KH, Frerker C.

Heart. 2016 Oct 1;102(19):1573-80. doi: 10.1136/heartjnl-2016-309597. Epub 2016 May 24.


Impact of Culprit Plaque and Atherothrombotic Components on Incomplete Stent Apposition in Patients With ST-Elevation Myocardial Infarction Treated With Everolimus-Eluting Stents - An OCTAVIA Substudy.

Bernelli C, Shimamura K, Komukai K, Capodanno D, Saia F, Garbo R, Burzotta F, Sirbu V, Coccato M, Campo G, Vignali L, Yamamoto H, Niccoli G, Ladich E, Biondi-Zoccai G, Guagliumi G.

Circ J. 2016;80(4):895-905. doi: 10.1253/circj.CJ-15-1140. Epub 2016 Feb 8.


Additive Value of Integrated Backscatter IVUS for Detection of Vulnerable Plaque by Optical Frequency Domain Imaging: An Ex Vivo Autopsy Study of Human Coronary Arteries.

Nakano M, Yahagi K, Yamamoto H, Taniwaki M, Otsuka F, Ladich ER, Joner M, Virmani R.

JACC Cardiovasc Imaging. 2016 Feb;9(2):163-72. doi: 10.1016/j.jcmg.2015.07.011. Epub 2016 Jan 6.


Cerebral Protection During MitraClip Implantation: Initial Experience at 2 Centers.

Frerker C, Schlüter M, Sanchez OD, Reith S, Romero ME, Ladich E, Schröder J, Schmidt T, Kreidel F, Joner M, Virmani R, Kuck KH.

JACC Cardiovasc Interv. 2016 Jan 25;9(2):171-9. doi: 10.1016/j.jcin.2015.09.039. Epub 2015 Dec 23.


Natural progression of atherosclerosis from pathologic intimal thickening to late fibroatheroma in human coronary arteries: A pathology study.

Otsuka F, Kramer MC, Woudstra P, Yahagi K, Ladich E, Finn AV, de Winter RJ, Kolodgie FD, Wight TN, Davis HR, Joner M, Virmani R.

Atherosclerosis. 2015 Aug;241(2):772-82. doi: 10.1016/j.atherosclerosis.2015.05.011. Epub 2015 May 19.


Neoatherosclerosis: overview of histopathologic findings and implications for intravascular imaging assessment.

Otsuka F, Byrne RA, Yahagi K, Mori H, Ladich E, Fowler DR, Kutys R, Xhepa E, Kastrati A, Virmani R, Joner M.

Eur Heart J. 2015 Aug 21;36(32):2147-59. doi: 10.1093/eurheartj/ehv205. Epub 2015 May 20. Review.


Thrombus formation following transcatheter aortic valve replacement.

De Marchena E, Mesa J, Pomenti S, Marin Y Kall C, Marincic X, Yahagi K, Ladich E, Kutz R, Aga Y, Ragosta M, Chawla A, Ring ME, Virmani R.

JACC Cardiovasc Interv. 2015 Apr 27;8(5):728-39. doi: 10.1016/j.jcin.2015.03.005. Review.


Comparison of histopathologic analysis following renal sympathetic denervation over multiple time points.

Sakakura K, Tunev S, Yahagi K, O'Brien AJ, Ladich E, Kolodgie FD, Melder RJ, Joner M, Virmani R.

Circ Cardiovasc Interv. 2015 Feb;8(2):e001813. doi: 10.1161/CIRCINTERVENTIONS.114.001813.


Hypersensitivity reaction in the US Food and Drug Administration-approved second-generation drug-eluting stents: histopathological assessment with ex vivo optical coherence tomography.

Otsuka F, Yahagi K, Ladich E, Kutys R, Alexander R, Fowler D, Virmani R, Joner M.

Circulation. 2015 Jan 20;131(3):322-4. doi: 10.1161/CIRCULATIONAHA.114.012658. No abstract available.


Comparison of renal artery, soft tissue, and nerve damage after irrigated versus nonirrigated radiofrequency ablation.

Sakakura K, Ladich E, Fuimaono K, Grunewald D, O'Fallon P, Spognardi AM, Markham P, Otsuka F, Yahagi K, Shen K, Kolodgie FD, Joner M, Virmani R.

Circ Cardiovasc Interv. 2014 Dec 31;8(1). pii: e001720. doi: 10.1161/CIRCINTERVENTIONS.114.001720. Print 2015 Jan.


Multiple simultaneous plaque erosion in 3 coronary arteries.

Yahagi K, Zarpak R, Sakakura K, Otsuka F, Kutys R, Ladich E, Fowler DR, Joner M, Virmani R.

JACC Cardiovasc Imaging. 2014 Nov;7(11):1172-4. doi: 10.1016/j.jcmg.2014.08.005. Epub 2014 Nov 10. No abstract available.


Controlled circumferential renal sympathetic denervation with preservation of the renal arterial wall using intraluminal ultrasound: a next-generation approach for treating sympathetic overactivity.

Sakakura K, Roth A, Ladich E, Shen K, Coleman L, Joner M, Virmani R.

EuroIntervention. 2015 Feb;10(10):1230-8. doi: 10.4244/EIJY14M10_14.


Methodological standardization for the pre-clinical evaluation of renal sympathetic denervation.

Sakakura K, Ladich E, Edelman ER, Markham P, Stanley JR, Keating J, Kolodgie FD, Virmani R, Joner M.

JACC Cardiovasc Interv. 2014 Oct;7(10):1184-93. doi: 10.1016/j.jcin.2014.04.024. Epub 2014 Sep 17. Review.


Mechanisms of atherothrombosis and vascular response to primary percutaneous coronary intervention in women versus men with acute myocardial infarction: results of the OCTAVIA study.

Guagliumi G, Capodanno D, Saia F, Musumeci G, Tarantini G, Garbo R, Tumminello G, Sirbu V, Coccato M, Fineschi M, Trani C, De Benedictis M, Limbruno U, De Luca L, Niccoli G, Bezerra H, Ladich E, Costa M, Biondi Zoccai G, Virmani R; OCTAVIA Trial Investigators.

JACC Cardiovasc Interv. 2014 Sep;7(9):958-68. doi: 10.1016/j.jcin.2014.05.011. Epub 2014 Aug 13.


Anatomic assessment of sympathetic peri-arterial renal nerves in man.

Sakakura K, Ladich E, Cheng Q, Otsuka F, Yahagi K, Fowler DR, Kolodgie FD, Virmani R, Joner M.

J Am Coll Cardiol. 2014 Aug 19;64(7):635-43. doi: 10.1016/j.jacc.2014.03.059.


Impact of Watchman and Amplatzer devices on left atrial appendage adjacent structures and healing response in a canine model.

Kar S, Hou D, Jones R, Werner D, Swanson L, Tischler B, Stein K, Huibregtse B, Ladich E, Kutys R, Virmani R.

JACC Cardiovasc Interv. 2014 Jul;7(7):801-9. doi: 10.1016/j.jcin.2014.03.003.


Long-term safety of an everolimus-eluting bioresorbable vascular scaffold and the cobalt-chromium XIENCE V stent in a porcine coronary artery model.

Otsuka F, Pacheco E, Perkins LE, Lane JP, Wang Q, Kamberi M, Frie M, Wang J, Sakakura K, Yahagi K, Ladich E, Rapoza RJ, Kolodgie FD, Virmani R.

Circ Cardiovasc Interv. 2014 Jun;7(3):330-42. doi: 10.1161/CIRCINTERVENTIONS.113.000990. Epub 2014 Jun 3.


Causes of early stent thrombosis in patients presenting with acute coronary syndrome: an ex vivo human autopsy study.

Nakano M, Yahagi K, Otsuka F, Sakakura K, Finn AV, Kutys R, Ladich E, Fowler DR, Joner M, Virmani R.

J Am Coll Cardiol. 2014 Jun 17;63(23):2510-2520. doi: 10.1016/j.jacc.2014.02.607. Epub 2014 Apr 23.


Pathophysiology of superficial femoral artery in-stent restenosis.

Yahagi K, Otsuka F, Sakakura K, Sanchez OD, Kutys R, Ladich E, Kolodgie FD, Virmani R, Joner M.

J Cardiovasc Surg (Torino). 2014 Jun;55(3):307-23. Review.


TGF-β signaling mediates endothelial-to-mesenchymal transition (EndMT) during vein graft remodeling.

Cooley BC, Nevado J, Mellad J, Yang D, St Hilaire C, Negro A, Fang F, Chen G, San H, Walts AD, Schwartzbeck RL, Taylor B, Lanzer JD, Wragg A, Elagha A, Beltran LE, Berry C, Feil R, Virmani R, Ladich E, Kovacic JC, Boehm M.

Sci Transl Med. 2014 Mar 12;6(227):227ra34. doi: 10.1126/scitranslmed.3006927.


Clinical use of optical coherence tomography to identify angiographic silent stent thrombosis.

Steigen SE, Holm NR, Butt N, Maeng M, Otsuka F, Virmani R, Ladich E, Steigen TK.

Scand Cardiovasc J. 2014 Jun;48(3):156-60. doi: 10.3109/14017431.2014.900185. Erratum in: Scand Cardiovasc J. 2014 Oct;48(5):323.


Response to letter regarding article, "Histopathology of embolic debris captured during transcatheter aortic valve replacement".

Van Mieghem NM, Schipper ME, Ladich E, Faqiri E, van der Boon R, Randjgari A, Schultz C, Moelker A, van Geuns RJ, Otsuka F, Serruys PW, Virmani R, de Jaegere PP.

Circulation. 2013 Dec 24;128(25):e478-9. doi: 10.1161/CIRCULATIONAHA.113.007267. No abstract available.


Pathology of second-generation everolimus-eluting stents versus first-generation sirolimus- and paclitaxel-eluting stents in humans.

Otsuka F, Vorpahl M, Nakano M, Foerst J, Newell JB, Sakakura K, Kutys R, Ladich E, Finn AV, Kolodgie FD, Virmani R.

Circulation. 2014 Jan 14;129(2):211-23. doi: 10.1161/CIRCULATIONAHA.113.001790. Epub 2013 Oct 25.


Comparison of pathology of chronic total occlusion with and without coronary artery bypass graft.

Sakakura K, Nakano M, Otsuka F, Yahagi K, Kutys R, Ladich E, Finn AV, Kolodgie FD, Virmani R.

Eur Heart J. 2014 Jul 1;35(25):1683-93. doi: 10.1093/eurheartj/eht422. Epub 2013 Oct 14.


Human autopsy study of drug-eluting stents restenosis: histomorphological predictors and neointimal characteristics.

Nakano M, Otsuka F, Yahagi K, Sakakura K, Kutys R, Ladich ER, Finn AV, Kolodgie FD, Virmani R.

Eur Heart J. 2013 Nov;34(42):3304-13. doi: 10.1093/eurheartj/eht241. Epub 2013 Jul 3.


Pathophysiology of renal denervation procedures: from renal nerve anatomy to procedural parameters.

Ammar S, Ladich E, Steigerwald K, Deisenhofer I, Joner M.

EuroIntervention. 2013 May;9 Suppl R:R89-95. doi: 10.4244/EIJV9SRA15. Review.


A pathologic study of explanted parachute devices from seven heart failure patients following percutaneous ventricular restoration.

Ladich E, Otsuka F, Virmani R.

Catheter Cardiovasc Interv. 2014 Mar 1;83(4):619-30.


Vascular, downstream, and pharmacokinetic responses to treatment with a low dose drug-coated balloon in a swine femoral artery model.

Yazdani SK, Pacheco E, Nakano M, Otsuka F, Naisbitt S, Kolodgie FD, Ladich E, Rousselle S, Virmani R.

Catheter Cardiovasc Interv. 2014 Jan 1;83(1):132-40. doi: 10.1002/ccd.24995. Epub 2013 Jul 3.


Histopathology of embolic debris captured during transcatheter aortic valve replacement.

Van Mieghem NM, Schipper ME, Ladich E, Faqiri E, van der Boon R, Randjgari A, Schultz C, Moelker A, van Geuns RJ, Otsuka F, Serruys PW, Virmani R, de Jaegere PP.

Circulation. 2013 Jun 4;127(22):2194-201. doi: 10.1161/CIRCULATIONAHA.112.001091. Epub 2013 May 7.


Unique demands of the femoral anatomy and pathology and the need for unique interventions.

Otsuka F, Nakano M, Sakakura K, Ladich E, Kolodgie FD, Virmani R.

J Cardiovasc Surg (Torino). 2013 Apr;54(2):191-210. Review.


Pathophysiology of atherosclerosis plaque progression.

Sakakura K, Nakano M, Otsuka F, Ladich E, Kolodgie FD, Virmani R.

Heart Lung Circ. 2013 Jun;22(6):399-411. doi: 10.1016/j.hlc.2013.03.001. Epub 2013 Mar 29. Review. Erratum in: Heart Lung Circ. 2014 Apr;23(4):387.


Pathology of Saphenous Vein Grafts.

Yazdani SK, Otsuka F, Nakano M, Ladich E, Virmani R.

Interv Cardiol Clin. 2013 Apr;2(2):241-249. doi: 10.1016/j.iccl.2012.11.002. Epub 2013 Jan 23. Review.


Pathologic Etiologies of Late and Very Late Stent Thrombosis following First-Generation Drug-Eluting Stent Placement.

Otsuka F, Nakano M, Ladich E, Kolodgie FD, Virmani R.

Thrombosis. 2012;2012:608593. doi: 10.1155/2012/608593. Epub 2012 Nov 21.


Pathology of drug-eluting versus bare-metal stents in saphenous vein bypass graft lesions.

Yazdani SK, Farb A, Nakano M, Vorpahl M, Ladich E, Finn AV, Kolodgie FD, Virmani R.

JACC Cardiovasc Interv. 2012 Jun;5(6):666-74. doi: 10.1016/j.jcin.2011.12.017.


Ex vivo assessment of vascular response to coronary stents by optical frequency domain imaging.

Nakano M, Vorpahl M, Otsuka F, Taniwaki M, Yazdani SK, Finn AV, Ladich ER, Kolodgie FD, Virmani R.

JACC Cardiovasc Imaging. 2012 Jan;5(1):71-82. doi: 10.1016/j.jcmg.2011.09.015.

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