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Infection is associated with one in five childhood deaths in England and Wales: analysis of national death registrations data, 2013-15.

Ferreras-Antolín L, Oligbu G, Okike IO, Ladhani S.

Arch Dis Child. 2020 Mar 24. pii: archdischild-2019-318001. doi: 10.1136/archdischild-2019-318001. [Epub ahead of print]


Coronavirus disease 2019 (covid-19): a guide for UK GPs.

Razai MS, Doerholt K, Ladhani S, Oakeshott P.

BMJ. 2020 Mar 5;368:m800. doi: 10.1136/bmj.m800. No abstract available. Erratum in: BMJ. 2020 Mar 11;368:m989.


Success of 4CMenB in preventing meningococcal disease: evidence from real-world experience.

Isitt C, Cosgrove CA, Ramsay ME, Ladhani SN.

Arch Dis Child. 2020 Feb 6. pii: archdischild-2019-318047. doi: 10.1136/archdischild-2019-318047. [Epub ahead of print] Review.


Meningococcal B Vaccine and Meningococcal Carriage in Adolescents in Australia.

Marshall HS, McMillan M, Koehler AP, Lawrence A, Sullivan TR, MacLennan JM, Maiden MCJ, Ladhani SN, Ramsay ME, Trotter C, Borrow R, Finn A, Kahler CM, Whelan J, Vadivelu K, Richmond P.

N Engl J Med. 2020 Jan 23;382(4):318-327. doi: 10.1056/NEJMoa1900236.


Vaccination of Infants with Meningococcal Group B Vaccine (4CMenB) in England.

Ladhani SN, Andrews N, Parikh SR, Campbell H, White J, Edelstein M, Bai X, Lucidarme J, Borrow R, Ramsay ME.

N Engl J Med. 2020 Jan 23;382(4):309-317. doi: 10.1056/NEJMoa1901229.


Characteristics of invasive pneumococcal disease (IPD) caused by emerging serotypes after the introduction of the 13-valent pneumococcal conjugate vaccine (PCV13) in England; prospective observational cohort study, 2014-18.

Amin-Chowdhury Z, Collins S, Sheppard C, Litt D, Fry NK, Andrews N, Ladhani SN.

Clin Infect Dis. 2020 Jan 19. pii: ciaa043. doi: 10.1093/cid/ciaa043. [Epub ahead of print]


Invasive meningococcal disease: Timing and cause of death in England, 2008-2015.

Beebeejaun K, Parikh SR, Campbell H, Gray S, Borrow R, Ramsay ME, Ladhani SN.

J Infect. 2020 Mar;80(3):286-290. doi: 10.1016/j.jinf.2019.12.008. Epub 2020 Jan 2.


Vaccine-derived rotavirus strains in infants in England.

Gower CM, Dunning J, Nawaz S, Allen D, Ramsay ME, Ladhani S.

Arch Dis Child. 2019 Dec 23. pii: archdischild-2019-317428. doi: 10.1136/archdischild-2019-317428. [Epub ahead of print]


Prophylactic Paracetamol After Meningococcal B Vaccination Reduces Postvaccination Fever and Septic Screens in Hospitalized Preterm Infants.

Dubus M, Ladhani S, Vasu V.

Pediatr Infect Dis J. 2020 Jan;39(1):78-80. doi: 10.1097/INF.0000000000002507.


Evolution of Streptococcus pneumoniae Serotype 3 in England and Wales: A Major Vaccine Evader.

Groves N, Sheppard CL, Litt D, Rose S, Silva A, Njoku N, Rodrigues S, Amin-Chowdhury Z, Andrews N, Ladhani S, Fry NK.

Genes (Basel). 2019 Oct 25;10(11). pii: E845. doi: 10.3390/genes10110845.


Variable clinical presentation by the main capsular groups causing invasive meningococcal disease in England.

Campbell H, Andrews N, Parikh S, Ribeiro S, Gray S, Lucidarme J, Ramsay ME, Borrow R, Ladhani SN.

J Infect. 2020 Feb;80(2):182-189. doi: 10.1016/j.jinf.2019.11.001. Epub 2019 Nov 9.


Primary meningococcal conjunctivitis: Summary of evidence for the clinical and public health management of cases and close contacts.

Parikh SR, Campbell H, Mandal S, Ramsay ME, Ladhani SN.

J Infect. 2019 Dec;79(6):490-494. doi: 10.1016/j.jinf.2019.10.015. Epub 2019 Oct 25.


UKMenCar4: A cross-sectional survey of asymptomatic meningococcal carriage amongst UK adolescents at a period of low invasive meningococcal disease incidence.

Bratcher HB, Rodrigues CMC, Finn A, Wootton M, Cameron JC, Smith A, Heath P, Ladhani S, Snape MD, Pollard AJ, Cunningham R, Borrow R, Trotter C, Gray SJ, Maiden MCJ, MacLennan JM.

Version 2. Wellcome Open Res. 2019 Oct 28 [revised 2019 Jan 1];4:118. doi: 10.12688/wellcomeopenres.15362.2. eCollection 2019.


Outbreaks of severe pneumococcal disease in closed settings in the conjugate vaccines era, 2010-2018: A systematic review to inform national guidance in the UK.

Amin-Chowdhury Z, Iyanger N, Ramsay ME, Ladhani SN.

J Infect. 2019 Dec;79(6):495-502. doi: 10.1016/j.jinf.2019.10.009. Epub 2019 Oct 18.


Pneumococcal serotype trends, surveillance and risk factors in UK adult pneumonia, 2013-18.

Pick H, Daniel P, Rodrigo C, Bewick T, Ashton D, Lawrence H, Baskaran V, Edwards-Pritchard RC, Sheppard C, Eletu SD, Rose S, Litt D, Fry NK, Ladhani S, Chand M, Trotter C, McKeever TM, Lim WS.

Thorax. 2020 Jan;75(1):38-49. doi: 10.1136/thoraxjnl-2019-213725. Epub 2019 Oct 8.


Effect of Pneumococcal Conjugate Vaccines on Pneumococcal Meningitis, England and Wales, July 1, 2000-June 30, 2016.

Oligbu G, Collins S, Djennad A, Sheppard CL, Fry NK, Andrews NJ, Borrow R, Ramsay ME, Ladhani SN.

Emerg Infect Dis. 2019 Sep;25(9):1708-1718. doi: 10.3201/eid2509.180747.


Aseptic meningitis associated with routine infant immunisation visits that include the group B meningococcal vaccine, 4CMenB.

Riordan A, Ladhani SN.

Arch Dis Child. 2019 Dec;104(12):1237-1238. doi: 10.1136/archdischild-2019-316811. Epub 2019 Aug 17. No abstract available.


Effectiveness of oral rotavirus vaccination in England against rotavirus-confirmed and all-cause acute gastroenteritis.

Walker JL, Andrews NJ, Atchison CJ, Collins S, Allen DJ, Ramsay ME, Ladhani SN, Thomas SL.

Vaccine X. 2019 Jan 4;1:100005. doi: 10.1016/j.jvacx.2019.100005. eCollection 2019 Apr 11.


Implementation of a Highly Accurate Rapid Point-of-Care Test for Group a Streptococcus Detection at a Large Pediatric Emergency Department in South London.

Demirjian A, Bustinduy AL, Ladhani S, Iqbal Y, Sharland M.

Pediatr Infect Dis J. 2019 Aug;38(8):e183-e185. doi: 10.1097/INF.0000000000002284.


Outbreak strain characterisation and pharyngeal carriage detection following a protracted group B meningococcal outbreak in adolescents in South-West England.

Clark SA, Lucidarme J, Angel G, Lekshmi A, Morales-Aza B, Willerton L, Campbell H, Gray SJ, Ladhani SN, Wade M, Ramsay M, Yates J, Finn A, Borrow R.

Sci Rep. 2019 Jul 10;9(1):9990. doi: 10.1038/s41598-019-46483-3.


Effectiveness of the seven-valent and thirteen-valent pneumococcal conjugate vaccines in England: The indirect cohort design, 2006-2018.

Andrews N, Kent A, Amin-Chowdhury Z, Sheppard C, Fry N, Ramsay M, Ladhani SN.

Vaccine. 2019 Jul 26;37(32):4491-4498. doi: 10.1016/j.vaccine.2019.06.071. Epub 2019 Jul 2.


Estimating age-stratified influenza-associated invasive pneumococcal disease in England: A time-series model based on population surveillance data.

Chiavenna C, Presanis AM, Charlett A, de Lusignan S, Ladhani S, Pebody RG, De Angelis D.

PLoS Med. 2019 Jun 27;16(6):e1002829. doi: 10.1371/journal.pmed.1002829. eCollection 2019 Jun.


Pneumococcal-related Hemolytic Uremic Syndrome in the United Kingdom: National Surveillance, 2006-2016.

Makwana A, Sheppard C, Fry NK, Ladhani SN.

Pediatr Infect Dis J. 2019 Oct;38(10):e254-e259. doi: 10.1097/INF.0000000000002368.


Smart Scheduling: Optimizing National Immunization Programs to Achieve Maximum Impact.

Ladhani SN, Ramsay ME.

Clin Infect Dis. 2020 Feb 3;70(4):684-686. doi: 10.1093/cid/ciz500. No abstract available.


Invasive meningococcal disease in patients with complement deficiencies: a case series (2008-2017).

Ladhani SN, Campbell H, Lucidarme J, Gray S, Parikh S, Willerton L, Clark SA, Lekshmi A, Walker A, Patel S, Bai X, Ramsay M, Borrow R.

BMC Infect Dis. 2019 Jun 14;19(1):522. doi: 10.1186/s12879-019-4146-5.


Effectiveness of 23-Valent Polysaccharide Pneumococcal Vaccine and Changes in Invasive Pneumococcal Disease Incidence from 2000 to 2017 in Those Aged 65 and Over in England and Wales.

Djennad A, Ramsay ME, Pebody R, Fry NK, Sheppard C, Ladhani SN, Andrews NJ.

EClinicalMedicine. 2019 Jan 2;6:42-50. doi: 10.1016/j.eclinm.2018.12.007. eCollection 2018 Dec.


Suspected cluster of Neisseria meningitidis W invasive disease in an elderly care home: do new laboratory methods aid public health action? United Kingdom, 2015.

Lawler J, Lucidarme J, Parikh S, Smith L, Campbell H, Borrow R, Gray S, Foster K, Ladhani S.

Euro Surveill. 2019 Jun;24(23). doi: 10.2807/1560-7917.ES.2019.24.23.1900070.


TIPICO IX: report of the 9th interactive infectious disease workshop on infectious diseases and vaccines.

Martinón-Torres F, Bosch X, Rappuoli R, Ladhani S, Redondo E, Vesikari T, García-Sastre A, Rivero-Calle I, Gómez-Rial J, Salas A, Martín C, Finn A, Butler R.

Hum Vaccin Immunother. 2019;15(10):2405-2415. doi: 10.1080/21645515.2019.1609823. Epub 2019 Jun 3.


Risk of invasive bacterial infections by week of age in infants: prospective national surveillance, England, 2010-2017.

Ladhani SN, Henderson KL, Muller-Pebody B, Ramsay ME, Riordan A.

Arch Dis Child. 2019 Sep;104(9):874-878. doi: 10.1136/archdischild-2018-316191. Epub 2019 May 30.


B Part of It School Leaver protocol: an observational repeat cross-sectional study to assess the impact of a meningococcal serogroup B (4CMenB) vaccine programme on carriage of Neisseria meningitidis.

Marshall HS, McMillan M, Koehler A, Lawrence A, MacLennan J, Maiden M, Ramsay M, Ladhani SN, Trotter C, Borrow R, Finn A, Sullivan T, Richmond P, Kahler C, Whelan J, Vadivelu K.

BMJ Open. 2019 May 6;9(5):e027233. doi: 10.1136/bmjopen-2018-027233.


Persistent Circulation of Vaccine Serotypes and Serotype Replacement After 5 Years of Infant Immunization With 13-Valent Pneumococcal Conjugate Vaccine in the United Kingdom.

Kandasamy R, Voysey M, Collins S, Berbers G, Robinson H, Noel I, Hughes H, Ndimah S, Gould K, Fry N, Sheppard C, Ladhani S, Snape MD, Hinds J, Pollard AJ.

J Infect Dis. 2020 Mar 28;221(8):1361-1370. doi: 10.1093/infdis/jiz178.


The Epidemiology and Biostatistics of Pneumococcus.

Oligbu G, Fry NK, Ladhani SN.

Methods Mol Biol. 2019;1968:215-224. doi: 10.1007/978-1-4939-9199-0_18.


The Pneumococcus and Its Critical Role in Public Health.

Oligbu G, Fry NK, Ladhani SN.

Methods Mol Biol. 2019;1968:205-213. doi: 10.1007/978-1-4939-9199-0_17.


Risk of invasive pneumococcal disease in children with sickle cell disease in the era of conjugate vaccines: a systematic review of the literature.

Oligbu G, Fallaha M, Pay L, Ladhani S.

Br J Haematol. 2019 May;185(4):743-751. doi: 10.1111/bjh.15846. Epub 2019 Mar 11.


Impact of rotavirus vaccination on rotavirus genotype distribution and diversity in England, September 2006 to August 2016.

Hungerford D, Allen DJ, Nawaz S, Collins S, Ladhani S, Vivancos R, Iturriza-Gómara M.

Euro Surveill. 2019 Feb;24(6). doi: 10.2807/1560-7917.ES.2019.24.6.1700774.


Serogroup C Neisseria meningitidis disease epidemiology, seroprevalence, vaccine effectiveness and waning immunity, England, 1998/99 to 2015/16.

Findlow H, Campbell H, Lucidarme J, Andrews N, Linley E, Ladhani S, Borrow R.

Euro Surveill. 2019 Jan;24(1). doi: 10.2807/1560-7917.ES.2019.24.1.1700818.


Enterovirus and parechovirus meningitis in infants younger than 90 days old in the UK and Republic of Ireland: a British Paediatric Surveillance Unit study.

Kadambari S, Braccio S, Ribeiro S, Allen DJ, Pebody R, Brown D, Cunney R, Sharland M, Ladhani S.

Arch Dis Child. 2019 Jun;104(6):552-557. doi: 10.1136/archdischild-2018-315643. Epub 2018 Dec 8.


Group B streptococcal disease in UK and Irish infants younger than 90 days, 2014-15: a prospective surveillance study.

O'Sullivan CP, Lamagni T, Patel D, Efstratiou A, Cunney R, Meehan M, Ladhani S, Reynolds AJ, Campbell R, Doherty L, Boyle M, Kapatai G, Chalker V, Lindsay D, Smith A, Davies E, Jones CE, Heath PT.

Lancet Infect Dis. 2019 Jan;19(1):83-90. doi: 10.1016/S1473-3099(18)30555-3. Epub 2018 Nov 26.


Invasive meningococcal disease as a cause of sudden and unexpected death in a teenager: The public health importance of confirming the diagnosis.

Campbell H, Borrow R, Arumugam C, Ramsay M, Ladhani SN.

J Infect. 2019 Apr;78(4):323-337. doi: 10.1016/j.jinf.2018.11.004. Epub 2018 Nov 23. No abstract available.


Effect of childhood pneumococcal conjugate vaccination on invasive disease in older adults of 10 European countries: implications for adult vaccination.

Hanquet G, Krizova P, Valentiner-Branth P, Ladhani SN, Nuorti JP, Lepoutre A, Mereckiene J, Knol M, Winje BA, Ciruela P, Ordobas M, Guevara M, McDonald E, Morfeldt E, Kozakova J, Slotved HC, Fry NK, Rinta-Kokko H, Varon E, Corcoran M, van der Ende A, Vestrheim DF, Munoz-Almagro C, Latasa P, Castilla J, Smith A, Henriques-Normark B, Whittaker R, Pastore Celentano L, Savulescu C; SpIDnet/I-MOVE+ Pneumo Group.

Thorax. 2019 May;74(5):473-482. doi: 10.1136/thoraxjnl-2018-211767. Epub 2018 Oct 24.


Cost-effectiveness analysis of maternal immunisation against group B Streptococcus (GBS) disease: A modelling study.

Giorgakoudi K, O'Sullivan C, Heath PT, Ladhani S, Lamagni T, Ramsay M, Al-Janabi H, Trotter C.

Vaccine. 2018 Nov 12;36(46):7033-7042. doi: 10.1016/j.vaccine.2018.09.058. Epub 2018 Oct 4.


Invasive Pneumococcal Disease in UK Children <1 Year of Age in the Post-13-Valent Pneumococcal Conjugate Vaccine Era: What Are the Risks Now?

Kent A, Makwana A, Sheppard CL, Collins S, Fry NK, Heath PT, Ramsay M, Ladhani SN.

Clin Infect Dis. 2019 Jun 18;69(1):84-90. doi: 10.1093/cid/ciy842.


Rapid Spread of Pneumococcal Nonvaccine Serotype 7C Previously Associated with Vaccine Serotype 19F, England and Wales.

Makwana A, Ladhani SN, Kapatai G, Campion E, Fry NK, Sheppard C.

Emerg Infect Dis. 2018 Oct;24(10):1919-1922. doi: 10.3201/eid2410.180114.


B Part of It protocol: a cluster randomised controlled trial to assess the impact of 4CMenB vaccine on pharyngeal carriage of Neisseria meningitidis in adolescents.

Marshall HS, McMillan M, Koehler A, Lawrence A, MacLennan JM, Maiden MCJ, Ramsay M, Ladhani SN, Trotter C, Borrow R, Finn A, Sullivan T, Richmond P, Kahler CM, Whelan J, Vadivelu K.

BMJ Open. 2018 Jul 10;8(7):e020988. doi: 10.1136/bmjopen-2017-020988.


Characteristics of Children With Invasive Pneumococcal Disease After the Introduction of the 13-valent Pneumococcal Conjugate Vaccine in England and Wales, 2010-2016.

Makwana A, Sheppard C, Borrow R, Fry N, Andrews NJ, Ladhani SN.

Pediatr Infect Dis J. 2018 Jul;37(7):697-703. doi: 10.1097/INF.0000000000001845.


Increased detection of human parechovirus infection in infants in England during 2016: epidemiology and clinical characteristics.

Ferreras Antolín L, Kadambari S, Braccio S, Tang JW, Xerry J, Allen DJ, Ladhani SN; Parechovirus Surveillance Network.

Arch Dis Child. 2018 Nov;103(11):1061-1066. doi: 10.1136/archdischild-2017-314281. Epub 2018 Jun 5.


Epidemiology, clinical presentation, risk factors, intensive care admission and outcomes of invasive meningococcal disease in England, 2010-2015.

Parikh SR, Campbell H, Gray SJ, Beebeejaun K, Ribeiro S, Borrow R, Ramsay ME, Ladhani SN.

Vaccine. 2018 Jun 18;36(26):3876-3881. doi: 10.1016/j.vaccine.2018.02.038. Epub 2018 Apr 24.


Safety of meningococcal group B vaccination in hospitalised premature infants.

Kent A, Beebeejaun K, Braccio S, Kadambari S, Clarke P, Heath PT, Ladhani S; National Neonatal Audit Network.

Arch Dis Child Fetal Neonatal Ed. 2019 Mar;104(2):F171-F175. doi: 10.1136/archdischild-2017-314152. Epub 2018 Apr 10.


Recommendations for enterovirus diagnostics and characterisation within and beyond Europe.

Harvala H, Broberg E, Benschop K, Berginc N, Ladhani S, Susi P, Christiansen C, McKenna J, Allen D, Makiello P, McAllister G, Carmen M, Zakikhany K, Dyrdak R, Nielsen X, Madsen T, Paul J, Moore C, von Eije K, Piralla A, Carlier M, Vanoverschelde L, Poelman R, Anton A, López-Labrador FX, Pellegrinelli L, Keeren K, Maier M, Cassidy H, Derdas S, Savolainen-Kopra C, Diedrich S, Nordbø S, Buesa J, Bailly JL, Baldanti F, MacAdam A, Mirand A, Dudman S, Schuffenecker I, Kadambari S, Neyts J, Griffiths MJ, Richter J, Margaretto C, Govind S, Morley U, Adams O, Krokstad S, Dean J, Pons-Salort M, Prochazka B, Cabrerizo M, Majumdar M, Nebbia G, Wiewel M, Cottrell S, Coyle P, Martin J, Moore C, Midgley S, Horby P, Wolthers K, Simmonds P, Niesters H, Fischer TK.

J Clin Virol. 2018 Apr;101:11-17. doi: 10.1016/j.jcv.2018.01.008. Epub 2018 Feb 6. Review.


Rapid increase in non-vaccine serotypes causing invasive pneumococcal disease in England and Wales, 2000-17: a prospective national observational cohort study.

Ladhani SN, Collins S, Djennad A, Sheppard CL, Borrow R, Fry NK, Andrews NJ, Miller E, Ramsay ME.

Lancet Infect Dis. 2018 Apr;18(4):441-451. doi: 10.1016/S1473-3099(18)30052-5. Epub 2018 Jan 26. Erratum in: Lancet Infect Dis. 2018 Feb 6;:.


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