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Items: 16

1.

ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer.

Xu G, Chhangawala S, Cocco E, Razavi P, Cai Y, Otto JE, Ferrando L, Selenica P, Ladewig E, Chan C, Da Cruz Paula A, Witkin M, Cheng Y, Park J, Serna-Tamayo C, Zhao H, Wu F, Sallaku M, Qu X, Zhao A, Collings CK, D'Avino AR, Jhaveri K, Koche R, Levine RL, Reis-Filho JS, Kadoch C, Scaltriti M, Leslie CS, Baselga J, Toska E.

Nat Genet. 2020 Jan 13. doi: 10.1038/s41588-019-0554-0. [Epub ahead of print]

PMID:
31932695
2.

Double PIK3CA mutations in cis increase oncogenicity and sensitivity to PI3Kα inhibitors.

Vasan N, Razavi P, Johnson JL, Shao H, Shah H, Antoine A, Ladewig E, Gorelick A, Lin TY, Toska E, Xu G, Kazmi A, Chang MT, Taylor BS, Dickler MN, Jhaveri K, Chandarlapaty S, Rabadan R, Reznik E, Smith ML, Sebra R, Schimmoller F, Wilson TR, Friedman LS, Cantley LC, Scaltriti M, Baselga J.

Science. 2019 Nov 8;366(6466):714-723. doi: 10.1126/science.aaw9032.

PMID:
31699932
3.

Distinct genomic profile and specific targeted drug responses in adult cerebellar glioblastoma.

Cho HJ, Zhao J, Jung SW, Ladewig E, Kong DS, Suh YL, Lee Y, Kim D, Ahn SH, Bordyuh M, Kang HJ, Sa JK, Seo YJ, Kim ST, Lim DH, Dho YS, Lee JI, Seol HJ, Choi JW, Park WY, Park CK, Rabadan R, Nam DH.

Neuro Oncol. 2019 Jan 1;21(1):47-58. doi: 10.1093/neuonc/noy123.

4.

Pervasive mutations of JAK-STAT pathway genes in classical Hodgkin lymphoma.

Tiacci E, Ladewig E, Schiavoni G, Penson A, Fortini E, Pettirossi V, Wang Y, Rosseto A, Venanzi A, Vlasevska S, Pacini R, Piattoni S, Tabarrini A, Pucciarini A, Bigerna B, Santi A, Gianni AM, Viviani S, Cabras A, Ascani S, Crescenzi B, Mecucci C, Pasqualucci L, Rabadan R, Falini B.

Blood. 2018 May 31;131(22):2454-2465. doi: 10.1182/blood-2017-11-814913. Epub 2018 Apr 12.

5.

Nuclear Proximity of Mtr4 to RNA Exosome Restricts DNA Mutational Asymmetry.

Lim J, Giri PK, Kazadi D, Laffleur B, Zhang W, Grinstein V, Pefanis E, Brown LM, Ladewig E, Martin O, Chen Y, Rabadan R, Boyer F, Rothschild G, Cogné M, Pinaud E, Deng H, Basu U.

Cell. 2017 Apr 20;169(3):523-537.e15. doi: 10.1016/j.cell.2017.03.043.

6.

Spatiotemporal genomic architecture informs precision oncology in glioblastoma.

Lee JK, Wang J, Sa JK, Ladewig E, Lee HO, Lee IH, Kang HJ, Rosenbloom DS, Camara PG, Liu Z, van Nieuwenhuizen P, Jung SW, Choi SW, Kim J, Chen A, Kim KT, Shin S, Seo YJ, Oh JM, Shin YJ, Park CK, Kong DS, Seol HJ, Blumberg A, Lee JI, Iavarone A, Park WY, Rabadan R, Nam DH.

Nat Genet. 2017 Apr;49(4):594-599. doi: 10.1038/ng.3806. Epub 2017 Mar 6.

7.

Clonal evolution of glioblastoma under therapy.

Wang J, Cazzato E, Ladewig E, Frattini V, Rosenbloom DI, Zairis S, Abate F, Liu Z, Elliott O, Shin YJ, Lee JK, Lee IH, Park WY, Eoli M, Blumberg AJ, Lasorella A, Nam DH, Finocchiaro G, Iavarone A, Rabadan R.

Nat Genet. 2016 Jul;48(7):768-76. doi: 10.1038/ng.3590. Epub 2016 Jun 6.

8.

Analysis of Nearly One Thousand Mammalian Mirtrons Reveals Novel Features of Dicer Substrates.

Wen J, Ladewig E, Shenker S, Mohammed J, Lai EC.

PLoS Comput Biol. 2015 Sep 1;11(9):e1004441. doi: 10.1371/journal.pcbi.1004441. eCollection 2015 Sep.

9.

Comparative analysis of the transcriptome across distant species.

Gerstein MB, Rozowsky J, Yan KK, Wang D, Cheng C, Brown JB, Davis CA, Hillier L, Sisu C, Li JJ, Pei B, Harmanci AO, Duff MO, Djebali S, Alexander RP, Alver BH, Auerbach R, Bell K, Bickel PJ, Boeck ME, Boley NP, Booth BW, Cherbas L, Cherbas P, Di C, Dobin A, Drenkow J, Ewing B, Fang G, Fastuca M, Feingold EA, Frankish A, Gao G, Good PJ, Guigó R, Hammonds A, Harrow J, Hoskins RA, Howald C, Hu L, Huang H, Hubbard TJ, Huynh C, Jha S, Kasper D, Kato M, Kaufman TC, Kitchen RR, Ladewig E, Lagarde J, Lai E, Leng J, Lu Z, MacCoss M, May G, McWhirter R, Merrihew G, Miller DM, Mortazavi A, Murad R, Oliver B, Olson S, Park PJ, Pazin MJ, Perrimon N, Pervouchine D, Reinke V, Reymond A, Robinson G, Samsonova A, Saunders GI, Schlesinger F, Sethi A, Slack FJ, Spencer WC, Stoiber MH, Strasbourger P, Tanzer A, Thompson OA, Wan KH, Wang G, Wang H, Watkins KL, Wen J, Wen K, Xue C, Yang L, Yip K, Zaleski C, Zhang Y, Zheng H, Brenner SE, Graveley BR, Celniker SE, Gingeras TR, Waterston R.

Nature. 2014 Aug 28;512(7515):445-8. doi: 10.1038/nature13424.

10.

Diversity of miRNAs, siRNAs, and piRNAs across 25 Drosophila cell lines.

Wen J, Mohammed J, Bortolamiol-Becet D, Tsai H, Robine N, Westholm JO, Ladewig E, Dai Q, Okamura K, Flynt AS, Zhang D, Andrews J, Cherbas L, Kaufman TC, Cherbas P, Siepel A, Lai EC.

Genome Res. 2014 Jul;24(7):1236-50. doi: 10.1101/gr.161554.113.

11.

Weighing children; parents agree, but GPs conflicted.

O'Shea B, Ladewig EL, Kelly A, Reulbach U, O'Dowd T.

Arch Dis Child. 2014 Jun;99(6):543-5. doi: 10.1136/archdischild-2013-304090. Epub 2014 Jan 15.

PMID:
24431419
12.

The influence of ethnicity on breastfeeding rates in Ireland: a cross-sectional study.

Ladewig EL, Hayes C, Browne J, Layte R, Reulbach U.

J Epidemiol Community Health. 2014 Apr;68(4):356-62. doi: 10.1136/jech-2013-202735. Epub 2013 Dec 13.

PMID:
24336238
13.

Functional small RNAs are generated from select miRNA hairpin loops in flies and mammals.

Okamura K, Ladewig E, Zhou L, Lai EC.

Genes Dev. 2013 Apr 1;27(7):778-92. doi: 10.1101/gad.211698.112. Epub 2013 Mar 27.

14.

Weight, body image and bullying in 9-year-old children.

Reulbach U, Ladewig EL, Nixon E, O'Moore M, Williams J, O'Dowd T.

J Paediatr Child Health. 2013 Apr;49(4):E288-93. doi: 10.1111/jpc.12159. Epub 2013 Mar 27.

PMID:
23530984
15.

Discovery of hundreds of mirtrons in mouse and human small RNA data.

Ladewig E, Okamura K, Flynt AS, Westholm JO, Lai EC.

Genome Res. 2012 Sep;22(9):1634-45. doi: 10.1101/gr.133553.111.

16.

Common and distinct patterns of terminal modifications to mirtrons and canonical microRNAs.

Westholm JO, Ladewig E, Okamura K, Robine N, Lai EC.

RNA. 2012 Feb;18(2):177-92. doi: 10.1261/rna.030627.111. Epub 2011 Dec 21.

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