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Items: 23

1.

CMX-2043 Mechanisms of Action In Vitro.

Lader AS, Baguisi A, Casale R, Kates SA, Beeuwkes R 3rd.

J Cardiovasc Pharmacol. 2016 Sep;68(3):241-7. doi: 10.1097/FJC.0000000000000408.

PMID:
27195653
2.

CMX-2043 Efficacy in a Rat Model of Cardiac Ischemia-Reperfusion Injury.

Baguisi A, Casale RA, Kates SA, Lader AS, Stewart K, Beeuwkes R 3rd.

J Cardiovasc Pharmacol Ther. 2016 Nov;21(6):563-569. Epub 2016 Apr 24.

PMID:
27113210
3.

Pre-clinical and Clinical Safety Studies of CMX-2043: a cytoprotective lipoic acid analogue for ischaemia-reperfusion injury.

Kates SA, Lader AS, Casale R, Beeuwkes R 3rd.

Basic Clin Pharmacol Toxicol. 2014 Nov;115(5):456-64. doi: 10.1111/bcpt.12254. Epub 2014 May 16.

4.

2-Arylpaullones are selective antitrypanosomal agents.

Ryczak J, Papini M, Lader A, Nasereddin A, Kopelyanskiy D, Preu L, Jaffe CL, Kunick C.

Eur J Med Chem. 2013 Jun;64:396-400. doi: 10.1016/j.ejmech.2013.03.065. Epub 2013 Apr 10.

PMID:
23648975
5.

Crotoxin potentiates L-type calcium currents and modulates the action potential of neonatal rat cardiomyocytes.

Zhang P, Lader AS, Etcheverry MA, Cantiello HF.

Toxicon. 2010 Jun 15;55(7):1236-43. doi: 10.1016/j.toxicon.2010.01.008. Epub 2010 Feb 1.

PMID:
20122949
6.

Development of 5-benzylpaullones and paullone-9-carboxylic acid alkyl esters as selective inhibitors of mitochondrial malate dehydrogenase (mMDH).

Becker A, Kohfeld S, Lader A, Preu L, Pies T, Wieking K, Ferandin Y, Knockaert M, Meijer L, Kunick C.

Eur J Med Chem. 2010 Jan;45(1):335-42. doi: 10.1016/j.ejmech.2009.10.018. Epub 2009 Oct 14.

PMID:
19906467
7.

Mechanisms of gelsolin-dependent and -independent EGF-stimulated cell motility in a human lung epithelial cell line.

Lader AS, Lee JJ, Cicchetti G, Kwiatkowski DJ.

Exp Cell Res. 2005 Jul 1;307(1):153-63. Epub 2005 Apr 7.

PMID:
15922735
8.

Functional expression and mutations of c-Met and its therapeutic inhibition with SU11274 and small interfering RNA in non-small cell lung cancer.

Ma PC, Jagadeeswaran R, Jagadeesh S, Tretiakova MS, Nallasura V, Fox EA, Hansen M, Schaefer E, Naoki K, Lader A, Richards W, Sugarbaker D, Husain AN, Christensen JG, Salgia R.

Cancer Res. 2005 Feb 15;65(4):1479-88.

9.

A mouse model of cardiac rhabdomyoma generated by loss of Tsc1 in ventricular myocytes.

Meikle L, McMullen JR, Sherwood MC, Lader AS, Walker V, Chan JA, Kwiatkowski DJ.

Hum Mol Genet. 2005 Feb 1;14(3):429-35. Epub 2004 Dec 15.

PMID:
15601645
10.

Efficacy of a rapamycin analog (CCI-779) and IFN-gamma in tuberous sclerosis mouse models.

Lee L, Sudentas P, Donohue B, Asrican K, Worku A, Walker V, Sun Y, Schmidt K, Albert MS, El-Hashemite N, Lader AS, Onda H, Zhang H, Kwiatkowski DJ, Dabora SL.

Genes Chromosomes Cancer. 2005 Mar;42(3):213-27.

PMID:
15578690
11.

Identification of a transcriptional profile associated with in vitro invasion in non-small cell lung cancer cell lines.

Lader AS, Ramoni MF, Zetter BR, Kohane IS, Kwiatkowski DJ.

Cancer Biol Ther. 2004 Jul;3(7):624-31. Epub 2004 Jul 9.

PMID:
15153803
12.

Characterization of Na+-permeable cation channels in LLC-PK1 renal epithelial cells.

Raychowdhury MK, Ibarra C, Damiano A, Jackson GR Jr, Smith PR, McLaughlin M, Prat AG, Ausiello DA, Lader AS, Cantiello HF.

J Biol Chem. 2004 May 7;279(19):20137-46. Epub 2004 Feb 24.

13.

Increased circulating levels of plasma ATP in cystic fibrosis patients.

Lader AS, Prat AG, Jackson GR Jr, Chervinsky KL, Lapey A, Kinane TB, Cantiello HF.

Clin Physiol. 2000 Sep;20(5):348-53.

PMID:
10971545
14.

cAMP activates an ATP-permeable pathway in neonatal rat cardiac myocytes.

Lader AS, Xiao YF, O'Riordan CR, Prat AG, Jackson GR Jr, Cantiello HF.

Am J Physiol Cell Physiol. 2000 Jul;279(1):C173-87.

15.

cAMP-activated anion conductance is associated with expression of CFTR in neonatal mouse cardiac myocytes.

Lader AS, Wang Y, Jackson GR Jr, Borkan SC, Cantiello HF.

Am J Physiol Cell Physiol. 2000 Feb;278(2):C436-50.

16.

Role of gelsolin in the actin filament regulation of cardiac L-type calcium channels.

Lader AS, Kwiatkowski DJ, Cantiello HF.

Am J Physiol. 1999 Dec;277(6):C1277-83. doi: 10.1152/ajpcell.1999.277.6.C1277.

PMID:
10600780
17.

Cardiac Gsalpha overexpression enhances L-type calcium channels through an adenylyl cyclase independent pathway.

Lader AS, Xiao YF, Ishikawa Y, Cui Y, Vatner DE, Vatner SF, Homcy CJ, Cantiello HF.

Proc Natl Acad Sci U S A. 1998 Aug 4;95(16):9669-74.

18.

Distribution of coronary arterial capacitance in a canine model.

Lader AS, Smith RS, Phillips GC, McNamee JE, Abel FL.

J Appl Physiol (1985). 1998 Mar;84(3):954-62.

19.

Direct action of endotoxin on cardiac muscle.

Starr RG, Lader AS, Phillips GC, Stroman CE, Abel FL.

Shock. 1995 May;3(5):380-4.

PMID:
7648341
20.

Effects of pericardial pressure on systemic and coronary hemodynamics in dogs.

Abel FL, Mihailescu LS, Lader AS, Starr RG.

Am J Physiol. 1995 Apr;268(4 Pt 2):H1593-605.

PMID:
7733360
21.

Alterations in left ventricular diastolic function in conscious dogs with pacing-induced heart failure.

Komamura K, Shannon RP, Pasipoularides A, Ihara T, Lader AS, Patrick TA, Bishop SP, Vatner SF.

J Clin Invest. 1992 Jun;89(6):1825-38.

22.

Changes in diastolic cardiac function in developing and stable perinephritic hypertension in conscious dogs.

Gelpi RJ, Pasipoularides A, Lader AS, Patrick TA, Chase N, Hittinger L, Shannon RP, Bishop SP, Vatner SF.

Circ Res. 1991 Feb;68(2):555-67.

PMID:
1991355
23.

Isoproterenol-induced alterations in myocardial blood flow, systolic and diastolic function in conscious dogs with heart failure.

Hittinger L, Shannon RP, Kohin S, Lader AS, Manders WT, Patrick TA, Kelly P, Vatner SF.

Circulation. 1989 Sep;80(3):658-68.

PMID:
2527646

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