Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 125

1.

Post-translational acylation controls the folding and functions of the CyaA RTX toxin.

O'Brien DP, Cannella SE, Voegele A, Raoux-Barbot D, Davi M, Douché T, Matondo M, Brier S, Ladant D, Chenal A.

FASEB J. 2019 Jun 21:fj201802442RR. doi: 10.1096/fj.201802442RR. [Epub ahead of print]

PMID:
31226003
2.

Editorial: Pathogens and disease special issue ETOX18.

Ladant D, Buchrieser C, Popoff MR.

Pathog Dis. 2019 Mar 1;77(2). pii: fty091. doi: 10.1093/femspd/fty091. No abstract available.

PMID:
31029064
3.

The Adenylate Cyclase (CyaA) Toxin from Bordetella pertussis Has No Detectable Phospholipase A (PLA) Activity In Vitro.

Voegele A, Sadi M, Raoux-Barbot D, Douché T, Matondo M, Ladant D, Chenal A.

Toxins (Basel). 2019 Feb 13;11(2). pii: E111. doi: 10.3390/toxins11020111.

4.

Translocation and calmodulin-activation of the adenylate cyclase toxin (CyaA) of Bordetella pertussis.

Voegele A, O'Brien DP, Subrini O, Sapay N, Cannella SE, Enguéné VYN, Hessel A, Karst J, Hourdel V, Perez ACS, Davi M, Veneziano R, Chopineau J, Vachette P, Durand D, Brier S, Ladant D, Chenal A.

Pathog Dis. 2018 Nov 1;76(8). doi: 10.1093/femspd/fty085. Review.

PMID:
30452651
5.

Differential regulation of actin-activated nucleotidyl cyclase virulence factors by filamentous and globular actin.

Raoux-Barbot D, Belyy A, Worpenberg L, Montluc S, Deville C, Henriot V, Velours C, Ladant D, Renault L, Mechold U.

PLoS One. 2018 Nov 12;13(11):e0206133. doi: 10.1371/journal.pone.0206133. eCollection 2018.

6.

The extreme C terminus of the Pseudomonas aeruginosa effector ExoY is crucial for binding to its eukaryotic activator, F-actin.

Belyy A, Santecchia I, Renault L, Bourigault B, Ladant D, Mechold U.

J Biol Chem. 2018 Dec 21;293(51):19785-19796. doi: 10.1074/jbc.RA118.003784. Epub 2018 Oct 30.

PMID:
30377256
7.

Bioengineering of Bordetella pertussis Adenylate Cyclase Toxin for Antigen-Delivery and Immunotherapy.

Chenal A, Ladant D.

Toxins (Basel). 2018 Jul 20;10(7). pii: E302. doi: 10.3390/toxins10070302. Review.

8.

A Bacterial Adenylate Cyclase-Based Two-Hybrid System Compatible with Gateway® Cloning.

Olson MG, Goldammer M, Gauliard E, Ladant D, Ouellette SP.

Methods Mol Biol. 2018;1794:75-96. doi: 10.1007/978-1-4939-7871-7_6.

PMID:
29855952
9.

Compartmentalized Cyclic AMP Production by the Bordetella pertussis and Bacillus anthracis Adenylate Cyclase Toxins Differentially Affects the Immune Synapse in T Lymphocytes.

Arumugham VB, Ulivieri C, Onnis A, Finetti F, Tonello F, Ladant D, Baldari CT.

Front Immunol. 2018 May 1;9:919. doi: 10.3389/fimmu.2018.00919. eCollection 2018.

10.

Lack of MHC class II molecules favors CD8+ T-cell infiltration into tumors associated with an increased control of tumor growth.

Chaoul N, Tang A, Desrues B, Oberkampf M, Fayolle C, Ladant D, Sainz-Perez A, Leclerc C.

Oncoimmunology. 2017 Dec 7;7(3):e1404213. doi: 10.1080/2162402X.2017.1404213. eCollection 2018.

11.

Calcium-dependent disorder-to-order transitions are central to the secretion and folding of the CyaA toxin of Bordetella pertussis, the causative agent of whooping cough.

O'Brien DP, Perez ACS, Karst J, Cannella SE, Enguéné VYN, Hessel A, Raoux-Barbot D, Voegele A, Subrini O, Davi M, Guijarro JI, Raynal B, Baron B, England P, Hernandez B, Ghomi M, Hourdel V, Malosse C, Chamot-Rooke J, Vachette P, Durand D, Brier S, Ladant D, Chenal A.

Toxicon. 2018 Jul;149:37-44. doi: 10.1016/j.toxicon.2018.01.007. Epub 2018 Jan 12. Review.

PMID:
29337218
12.

Calmodulin fishing with a structurally disordered bait triggers CyaA catalysis.

O'Brien DP, Durand D, Voegele A, Hourdel V, Davi M, Chamot-Rooke J, Vachette P, Brier S, Ladant D, Chenal A.

PLoS Biol. 2017 Dec 29;15(12):e2004486. doi: 10.1371/journal.pbio.2004486. eCollection 2017 Dec.

13.

ExoY, an actin-activated nucleotidyl cyclase toxin from P. aeruginosa: A minireview.

Belyy A, Mechold U, Renault L, Ladant D.

Toxicon. 2018 Jul;149:65-71. doi: 10.1016/j.toxicon.2017.12.046. Epub 2017 Dec 16. Review.

14.

Membrane-Active Properties of an Amphitropic Peptide from the CyaA Toxin Translocation Region.

Voegele A, Subrini O, Sapay N, Ladant D, Chenal A.

Toxins (Basel). 2017 Nov 14;9(11). pii: E369. doi: 10.3390/toxins9110369.

15.

Synthesis and characterization of tethered lipid assemblies for membrane protein reconstitution (Review).

Veneziano R, Rossi C, Chenal A, Brenner C, Ladant D, Chopineau J.

Biointerphases. 2017 Sep 28;12(4):04E301. doi: 10.1116/1.4994299. Review.

PMID:
28958150
16.

SEC-SAXS and HDX-MS: A powerful combination. The case of the calcium-binding domain of a bacterial toxin.

O'Brien DP, Brier S, Ladant D, Durand D, Chenal A, Vachette P.

Biotechnol Appl Biochem. 2018 Jan;65(1):62-68. doi: 10.1002/bab.1577. Epub 2017 Oct 2. Review.

PMID:
28770577
17.

Protein-Protein Interaction: Bacterial Two-Hybrid.

Karimova G, Gauliard E, Davi M, Ouellette SP, Ladant D.

Methods Mol Biol. 2017;1615:159-176. doi: 10.1007/978-1-4939-7033-9_13.

PMID:
28667611
18.

Defining Membrane Protein Topology Using pho-lac Reporter Fusions.

Karimova G, Ladant D.

Methods Mol Biol. 2017;1615:129-142. doi: 10.1007/978-1-4939-7033-9_10.

PMID:
28667608
19.

Exposure to Bordetella pertussis adenylate cyclase toxin affects integrin-mediated adhesion and mechanics in alveolar epithelial cells.

Angely C, Nguyen NM, Andre Dias S, Planus E, Pelle G, Louis B, Filoche M, Chenal A, Ladant D, Isabey D.

Biol Cell. 2017 Aug;109(8):293-311. doi: 10.1111/boc.201600082. Epub 2017 Jul 26.

PMID:
28597954
20.

Analysis of Membrane Protein Interactions with a Bacterial Adenylate Cyclase-Based Two-Hybrid (BACTH) Technique.

Ouellette SP, Karimova G, Davi M, Ladant D.

Curr Protoc Mol Biol. 2017 Apr 3;118:20.12.1-20.12.24. doi: 10.1002/cpmb.36.

PMID:
28369675
21.

Stability, structural and functional properties of a monomeric, calcium-loaded adenylate cyclase toxin, CyaA, from Bordetella pertussis.

Cannella SE, Ntsogo Enguéné VY, Davi M, Malosse C, Sotomayor Pérez AC, Chamot-Rooke J, Vachette P, Durand D, Ladant D, Chenal A.

Sci Rep. 2017 Feb 10;7:42065. doi: 10.1038/srep42065.

22.

Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins.

Belyy A, Raoux-Barbot D, Saveanu C, Namane A, Ogryzko V, Worpenberg L, David V, Henriot V, Fellous S, Merrifield C, Assayag E, Ladant D, Renault L, Mechold U.

Nat Commun. 2016 Dec 5;7:13582. doi: 10.1038/ncomms13582.

23.

Structural models of intrinsically disordered and calcium-bound folded states of a protein adapted for secretion.

O'Brien DP, Hernandez B, Durand D, Hourdel V, Sotomayor-Pérez AC, Vachette P, Ghomi M, Chamot-Rooke J, Ladant D, Brier S, Chenal A.

Sci Rep. 2015 Sep 16;5:14223. doi: 10.1038/srep14223.

24.

Rapamycin Impairs Antitumor CD8+ T-cell Responses and Vaccine-Induced Tumor Eradication.

Chaoul N, Fayolle C, Desrues B, Oberkampf M, Tang A, Ladant D, Leclerc C.

Cancer Res. 2015 Aug 15;75(16):3279-91. doi: 10.1158/0008-5472.CAN-15-0454. Epub 2015 Jun 29.

25.

Characterization of interactions between inclusion membrane proteins from Chlamydia trachomatis.

Gauliard E, Ouellette SP, Rueden KJ, Ladant D.

Front Cell Infect Microbiol. 2015 Feb 11;5:13. doi: 10.3389/fcimb.2015.00013. eCollection 2015.

26.

Disorder-to-order transition in the CyaA toxin RTX domain: implications for toxin secretion.

Sotomayor-Pérez AC, Ladant D, Chenal A.

Toxins (Basel). 2014 Dec 31;7(1):1-20. doi: 10.3390/toxins7010001. Review.

27.

Calcium, acylation, and molecular confinement favor folding of Bordetella pertussis adenylate cyclase CyaA toxin into a monomeric and cytotoxic form.

Karst JC, Ntsogo Enguéné VY, Cannella SE, Subrini O, Hessel A, Debard S, Ladant D, Chenal A.

J Biol Chem. 2014 Oct 31;289(44):30702-16. doi: 10.1074/jbc.M114.580852. Epub 2014 Sep 17.

28.

Antigen targeting to CD11b+ dendritic cells in association with TLR4/TRIF signaling promotes strong CD8+ T cell responses.

Dadaglio G, Fayolle C, Zhang X, Ryffel B, Oberkampf M, Felix T, Hervas-Stubbs S, Osicka R, Sebo P, Ladant D, Leclerc C.

J Immunol. 2014 Aug 15;193(4):1787-98. doi: 10.4049/jimmunol.1302974. Epub 2014 Jul 14.

29.

A Gateway(®) -compatible bacterial adenylate cyclase-based two-hybrid system.

Ouellette SP, Gauliard E, Antosová Z, Ladant D.

Environ Microbiol Rep. 2014 Jun;6(3):259-67. doi: 10.1111/1758-2229.12123. Epub 2013 Nov 25.

PMID:
24983530
30.

ExoY from Pseudomonas aeruginosa is a nucleotidyl cyclase with preference for cGMP and cUMP formation.

Beckert U, Wolter S, Hartwig C, Bähre H, Kaever V, Ladant D, Frank DW, Seifert R.

Biochem Biophys Res Commun. 2014 Jul 18;450(1):870-4. doi: 10.1016/j.bbrc.2014.06.088. Epub 2014 Jun 24.

31.

Analysis of MreB interactors in Chlamydia reveals a RodZ homolog but fails to detect an interaction with MraY.

Ouellette SP, Rueden KJ, Gauliard E, Persons L, de Boer PA, Ladant D.

Front Microbiol. 2014 Jun 6;5:279. doi: 10.3389/fmicb.2014.00279. eCollection 2014.

32.

Allosteric activation of Bordetella pertussis adenylyl cyclase by calmodulin: molecular dynamics and mutagenesis studies.

Selwa E, Davi M, Chenal A, Sotomayor-Pérez AC, Ladant D, Malliavin TE.

J Biol Chem. 2014 Jul 25;289(30):21131-41.

33.

ZapE is a novel cell division protein interacting with FtsZ and modulating the Z-ring dynamics.

Marteyn BS, Karimova G, Fenton AK, Gazi AD, West N, Touqui L, Prevost MC, Betton JM, Poyraz O, Ladant D, Gerdes K, Sansonetti PJ, Tang CM.

MBio. 2014 Mar 4;5(2):e00022-14. doi: 10.1128/mBio.00022-14.

34.

Bordetella pertussis adenylate cyclase toxin translocation across a tethered lipid bilayer.

Veneziano R, Rossi C, Chenal A, Devoisselle JM, Ladant D, Chopineau J.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):20473-8. doi: 10.1073/pnas.1312975110. Epub 2013 Dec 2.

35.

Characterization of a membrane-active peptide from the Bordetella pertussis CyaA toxin.

Subrini O, Sotomayor-Pérez AC, Hessel A, Spiaczka-Karst J, Selwa E, Sapay N, Veneziano R, Pansieri J, Chopineau J, Ladant D, Chenal A.

J Biol Chem. 2013 Nov 8;288(45):32585-98. doi: 10.1074/jbc.M113.508838. Epub 2013 Sep 24.

36.

Molecular crowding stabilizes both the intrinsically disordered calcium-free state and the folded calcium-bound state of a repeat in toxin (RTX) protein.

Sotomayor-Pérez AC, Subrini O, Hessel A, Ladant D, Chenal A.

J Am Chem Soc. 2013 Aug 14;135(32):11929-34. doi: 10.1021/ja404790f. Epub 2013 Jul 31.

PMID:
23941183
37.

Molecular motions as a drug target: mechanistic simulations of anthrax toxin edema factor function led to the discovery of novel allosteric inhibitors.

Laine E, Martínez L, Ladant D, Malliavin T, Blondel A.

Toxins (Basel). 2012 Aug;4(8):580-604. Epub 2012 Jul 31. Review.

38.
39.

Mean net charge of intrinsically disordered proteins: experimental determination of protein valence by electrophoretic mobility measurements.

Sotomayor-Pérez AC, Karst JC, Ladant D, Chenal A.

Methods Mol Biol. 2012;896:331-49. doi: 10.1007/978-1-4614-3704-8_22.

PMID:
22821535
40.

Estimation of intrinsically disordered protein shape and time-averaged apparent hydration in native conditions by a combination of hydrodynamic methods.

Karst JC, Sotomayor-Pérez AC, Ladant D, Chenal A.

Methods Mol Biol. 2012;896:163-77. doi: 10.1007/978-1-4614-3704-8_10.

PMID:
22821523
41.

Chlamydia co-opts the rod shape-determining proteins MreB and Pbp2 for cell division.

Ouellette SP, Karimova G, Subtil A, Ladant D.

Mol Microbiol. 2012 Jul;85(1):164-78. doi: 10.1111/j.1365-2958.2012.08100.x. Epub 2012 Jun 7.

42.

Large-scale study of the interactions between proteins involved in type IV pilus biology in Neisseria meningitidis: characterization of a subcomplex involved in pilus assembly.

Georgiadou M, Castagnini M, Karimova G, Ladant D, Pelicic V.

Mol Microbiol. 2012 Jun;84(5):857-73. doi: 10.1111/j.1365-2958.2012.08062.x. Epub 2012 Apr 24.

43.

Identification of a region that assists membrane insertion and translocation of the catalytic domain of Bordetella pertussis CyaA toxin.

Karst JC, Barker R, Devi U, Swann MJ, Davi M, Roser SJ, Ladant D, Chenal A.

J Biol Chem. 2012 Mar 16;287(12):9200-12. doi: 10.1074/jbc.M111.316166. Epub 2012 Jan 12.

44.

3'-5' phosphoadenosine phosphate is an inhibitor of PARP-1 and a potential mediator of the lithium-dependent inhibition of PARP-1 in vivo.

Toledano E, Ogryzko V, Danchin A, Ladant D, Mechold U.

Biochem J. 2012 Apr 15;443(2):485-90. doi: 10.1042/BJ20111057.

45.

Role of leucine zipper motifs in association of the Escherichia coli cell division proteins FtsL and FtsB.

Robichon C, Karimova G, Beckwith J, Ladant D.

J Bacteriol. 2011 Sep;193(18):4988-92. doi: 10.1128/JB.00324-11. Epub 2011 Jul 22.

46.

Oral macrophage-like cells play a key role in tolerance induction following sublingual immunotherapy of asthmatic mice.

Mascarell L, Saint-Lu N, Moussu H, Zimmer A, Louise A, Lone Y, Ladant D, Leclerc C, Tourdot S, Van Overtvelt L, Moingeon P.

Mucosal Immunol. 2011 Nov;4(6):638-47. doi: 10.1038/mi.2011.28. Epub 2011 Jul 20.

PMID:
21775981
47.

The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse.

Paccani SR, Finetti F, Davi M, Patrussi L, D'Elios MM, Ladant D, Baldari CT.

J Exp Med. 2011 Jun 6;208(6):1317-30. doi: 10.1084/jem.20101558. Epub 2011 May 16.

48.

A tethered bilayer assembled on top of immobilized calmodulin to mimic cellular compartmentalization.

Rossi C, Doumiati S, Lazzarelli C, Davi M, Meddar F, Ladant D, Chopineau J.

PLoS One. 2011 Apr 20;6(4):e19101. doi: 10.1371/journal.pone.0019101.

49.

Calcium-induced folding of intrinsically disordered repeat-in-toxin (RTX) motifs via changes of protein charges and oligomerization states.

Sotomayor-Pérez AC, Ladant D, Chenal A.

J Biol Chem. 2011 May 13;286(19):16997-7004. doi: 10.1074/jbc.M110.210393. Epub 2011 Mar 15.

50.

Calcium-induced folding and stabilization of the intrinsically disordered RTX domain of the CyaA toxin.

Chenal A, Karst JC, Sotomayor Pérez AC, Wozniak AK, Baron B, England P, Ladant D.

Biophys J. 2010 Dec 1;99(11):3744-53. doi: 10.1016/j.bpj.2010.10.016.

Supplemental Content

Loading ...
Support Center