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Items: 1 to 20 of 38


A KLF4-DYRK2-mediated pathway regulating self-renewal in CML stem cells.

Park CS, Lewis AH, Chen TJ, Bridges CS, Shen Y, Suppipat K, Puppi M, Tomolonis JA, Pang PD, Mistretta TA, Ma L, Green MR, Rau R, Lacorazza HD.

Blood. 2019 Nov 28;134(22):1960-1972. doi: 10.1182/blood.2018875922.


KLF4 represses MAP2K7 signaling in T-ALL.

Lacorazza HD.

Oncotarget. 2017 Sep 6;8(43):73366-73367. doi: 10.18632/oncotarget.20672. eCollection 2017 Sep 26. No abstract available.


Retroviral Transduction of Quiescent Murine Hematopoietic Stem Cells.

Park CS, Lacorazza HD.

Methods Mol Biol. 2018;1686:173-182. doi: 10.1007/978-1-4939-7371-2_13.


Novel tumor-suppressor function of KLF4 in pediatric T-cell acute lymphoblastic leukemia.

Shen Y, Chen TJ, Lacorazza HD.

Exp Hematol. 2017 Sep;53:16-25. doi: 10.1016/j.exphem.2017.04.009. Epub 2017 May 4. Review.


Inactivation of KLF4 promotes T-cell acute lymphoblastic leukemia and activates the MAP2K7 pathway.

Shen Y, Park CS, Suppipat K, Mistretta TA, Puppi M, Horton TM, Rabin K, Gray NS, Meijerink JPP, Lacorazza HD.

Leukemia. 2017 Jun;31(6):1314-1324. doi: 10.1038/leu.2016.339. Epub 2016 Nov 22.


Role of the reprogramming factor KLF4 in blood formation.

Park CS, Shen Y, Lewis A, Lacorazza HD.

J Leukoc Biol. 2016 May;99(5):673-85. doi: 10.1189/jlb.1RU1215-539R. Epub 2016 Feb 23. Review.


Loss of n-6 fatty acid induced pediatric obesity protects against acute murine colitis.

Nagy-Szakal D, Mir SA, Harris RA, Dowd SE, Yamada T, Lacorazza HD, Tatevian N, Smith CW, de Zoeten EF, Klein J, Kellermayer R.

FASEB J. 2015 Aug;29(8):3151-9. doi: 10.1096/fj.14-267690. Epub 2015 Apr 22.


G0S2 modulates homeostatic proliferation of naïve CD8⁺ T cells and inhibits oxidative phosphorylation in mitochondria.

Lee PH, Yamada T, Park CS, Shen Y, Puppi M, Lacorazza HD.

Immunol Cell Biol. 2015 Aug;93(7):605-15. doi: 10.1038/icb.2015.9. Epub 2015 Feb 10.


From the Table to the Bedside: Can Food-Derived Sulforaphane be used as a Novel Agent to Treat Leukemia?

Suppipat K, Lacorazza HD.

Curr Cancer Drug Targets. 2014;14(5):434-45. Review.


Transcription factor ELF4 promotes development and function of memory CD8(+) T cells in Listeria monocytogenes infection.

Mamonkin M, Puppi M, Lacorazza HD.

Eur J Immunol. 2014 Mar;44(3):715-27. doi: 10.1002/eji.201343775. Epub 2014 Jan 13.


The transcription factor E74-like factor 4 suppresses differentiation of proliferating CD4+ T cells to the Th17 lineage.

Lee PH, Puppi M, Schluns KS, Yu-Lee LY, Dong C, Lacorazza HD.

J Immunol. 2014 Jan 1;192(1):178-88. doi: 10.4049/jimmunol.1301372. Epub 2013 Nov 20.


G0S2 inhibits the proliferation of K562 cells by interacting with nucleolin in the cytosol.

Yamada T, Park CS, Shen Y, Rabin KR, Lacorazza HD.

Leuk Res. 2014 Feb;38(2):210-7. doi: 10.1016/j.leukres.2013.10.006. Epub 2013 Oct 14.


Differential roles of KLF4 in the development and differentiation of CD8+ T cells.

Mamonkin M, Shen Y, Lee PH, Puppi M, Park CS, Lacorazza HD.

Immunol Lett. 2013 Nov-Dec;156(1-2):94-101. doi: 10.1016/j.imlet.2013.09.008. Epub 2013 Sep 25.


Genetic control of quiescence in hematopoietic stem cells.

Yamada T, Park CS, Lacorazza HD.

Cell Cycle. 2013 Aug 1;12(15):2376-83. doi: 10.4161/cc.25416. Epub 2013 Jun 28. Review.


Sulforaphane induces cell cycle arrest and apoptosis in acute lymphoblastic leukemia cells.

Suppipat K, Park CS, Shen Y, Zhu X, Lacorazza HD.

PLoS One. 2012;7(12):e51251. doi: 10.1371/journal.pone.0051251. Epub 2012 Dec 12.


The cytosolic protein G0S2 maintains quiescence in hematopoietic stem cells.

Yamada T, Park CS, Burns A, Nakada D, Lacorazza HD.

PLoS One. 2012;7(5):e38280. doi: 10.1371/journal.pone.0038280. Epub 2012 May 31.


Kruppel-like factor 4 (KLF4) promotes the survival of natural killer cells and maintains the number of conventional dendritic cells in the spleen.

Park CS, Lee PH, Yamada T, Burns A, Shen Y, Puppi M, Lacorazza HD.

J Leukoc Biol. 2012 May;91(5):739-50. doi: 10.1189/jlb.0811413. Epub 2012 Feb 17.


The transcription factor E74-like factor controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow.

Sivina M, Yamada T, Park CS, Puppi M, Coskun S, Hirschi K, Lacorazza HD.

Arterioscler Thromb Vasc Biol. 2011 May;31(5):1185-91. doi: 10.1161/ATVBAHA.111.224436. Epub 2011 Feb 24.


Cutting edge: Expression of the transcription factor E74-like factor 4 is regulated by the mammalian target of rapamycin pathway in CD8+ T cells.

Yamada T, Gierach K, Lee PH, Wang X, Lacorazza HD.

J Immunol. 2010 Oct 1;185(7):3824-8. doi: 10.4049/jimmunol.1000718. Epub 2010 Aug 27.


Transcription factor ELF4 controls the proliferation and homing of CD8+ T cells via the Krüppel-like factors KLF4 and KLF2.

Yamada T, Park CS, Mamonkin M, Lacorazza HD.

Nat Immunol. 2009 Jun;10(6):618-26. doi: 10.1038/ni.1730. Epub 2009 May 3.

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