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Items: 1 to 50 of 77

1.

Massively parallel and multiplex blood group genotyping using next-generation-sequencing.

Boccoz SA, Fouret J, Roche M, Lachuer J, Legras-Lachuer C, Corgier BP, Marquette CA.

Clin Biochem. 2018 Sep;60:71-76. doi: 10.1016/j.clinbiochem.2018.07.010. Epub 2018 Aug 7.

PMID:
30092181
2.

The microglial reaction signature revealed by RNAseq from individual mice.

Hirbec H, Marmai C, Duroux-Richard I, Roubert C, Esclangon A, Croze S, Lachuer J, Peyroutou R, Rassendren F.

Glia. 2018 May;66(5):971-986. doi: 10.1002/glia.23295. Epub 2018 Feb 5.

PMID:
29399880
3.

Down-expression of P2RX2, KCNQ5, ERBB3 and SOCS3 through DNA hypermethylation in elderly women with presbycusis.

Bouzid A, Smeti I, Dhouib L, Roche M, Achour I, Khalfallah A, Gibriel AA, Charfeddine I, Ayadi H, Lachuer J, Ghorbel A, Petit C, Masmoudi S.

Biomarkers. 2018 May - Jun;23(4):347-356. doi: 10.1080/1354750X.2018.1427795. Epub 2018 Jan 31.

PMID:
29325454
4.

Predicting thyroid nodule malignancy at several prevalence values with a combined Bethesda-molecular test.

Lasolle H, Riche B, Decaussin-Petrucci M, Dantony E, Lapras V, Cornu C, Lachuer J, Peix JL, Lifante JC, Capraru OM, Selmi-Ruby S, Rousset B, Borson-Chazot F, Roy P.

Transl Res. 2017 Oct;188:58-66.e1. doi: 10.1016/j.trsl.2017.07.005. Epub 2017 Jul 22.

PMID:
28797549
5.

Atrial fibrillation is associated with hypermethylation in human left atrium, and treatment with decitabine reduces atrial tachyarrhythmias in spontaneously hypertensive rats.

Doñate Puertas R, Meugnier E, Romestaing C, Rey C, Morel E, Lachuer J, Gadot N, Scridon A, Julien C, Tronc F, Chapuis B, Valla C, Janin A, Pirola L, Méjat A, Rome S, Chevalier P.

Transl Res. 2017 Jun;184:57-67.e5. doi: 10.1016/j.trsl.2017.03.004. Epub 2017 Mar 30.

PMID:
28427903
6.

A stemness-related ZEB1-MSRB3 axis governs cellular pliancy and breast cancer genome stability.

Morel AP, Ginestier C, Pommier RM, Cabaud O, Ruiz E, Wicinski J, Devouassoux-Shisheboran M, Combaret V, Finetti P, Chassot C, Pinatel C, Fauvet F, Saintigny P, Thomas E, Moyret-Lalle C, Lachuer J, Despras E, Jauffret JL, Bertucci F, Guitton J, Wierinckx A, Wang Q, Radosevic-Robin N, Penault-Llorca F, Cox DG, Hollande F, Ansieau S, Caramel J, Birnbaum D, Vigneron AM, Tissier A, Charafe-Jauffret E, Puisieux A.

Nat Med. 2017 May;23(5):568-578. doi: 10.1038/nm.4323. Epub 2017 Apr 10.

PMID:
28394329
7.

MicroRNAs in pituitary tumors.

Wierinckx A, Roche M, Legras-Lachuer C, Trouillas J, Raverot G, Lachuer J.

Mol Cell Endocrinol. 2017 Nov 15;456:51-61. doi: 10.1016/j.mce.2017.01.021. Epub 2017 Jan 13. Review.

PMID:
28089822
8.

Refilins are short-lived Actin-bundling proteins that regulate lamellipodium protrusion dynamics.

Gay O, Gilquin B, Assard N, Stuelsatz P, Delphin C, Lachuer J, Gidrol X, Baudier J.

Biol Open. 2016 Oct 15;5(10):1351-1361. doi: 10.1242/bio.019588.

9.

Alterations of circulating lymphoid committed progenitor cellular metabolism after allogeneic stem cell transplantation in humans.

Glauzy S, Peffault de Latour R, André-Schmutz I, Lachuer J, Servais S, Socié G, Clave E, Toubert A.

Exp Hematol. 2016 Sep;44(9):811-816.e3. doi: 10.1016/j.exphem.2016.05.008. Epub 2016 Jun 17.

PMID:
27321893
10.

CD1d-restricted peripheral T cell lymphoma in mice and humans.

Bachy E, Urb M, Chandra S, Robinot R, Bricard G, de Bernard S, Traverse-Glehen A, Gazzo S, Blond O, Khurana A, Baseggio L, Heavican T, Ffrench M, Crispatzu G, Mondière P, Schrader A, Taillardet M, Thaunat O, Martin N, Dalle S, Le Garff-Tavernier M, Salles G, Lachuer J, Hermine O, Asnafi V, Roussel M, Lamy T, Herling M, Iqbal J, Buffat L, Marche PN, Gaulard P, Kronenberg M, Defrance T, Genestier L.

J Exp Med. 2016 May 2;213(5):841-57. doi: 10.1084/jem.20150794. Epub 2016 Apr 11.

11.

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer.

Foy JP, Tortereau A, Caulin C, Le Texier V, Lavergne E, Thomas E, Chabaud S, Perol D, Lachuer J, Lang W, Hong WK, Goudot P, Lippman SM, Bertolus C, Saintigny P.

Oncotarget. 2016 Jun 14;7(24):35932-35945. doi: 10.18632/oncotarget.8321.

12.

Rare Circulating Cells in Familial Waldenström Macroglobulinemia Displaying the MYD88 L265P Mutation Are Enriched by Epstein-Barr Virus Immortalization.

Pertesi M, Galia P, Nazaret N, Vallée M, Garderet L, Leleu X, Avet-Loiseau H, Foll M, Byrnes G, Lachuer J, McKay JD, Dumontet C.

PLoS One. 2015 Sep 9;10(9):e0136505. doi: 10.1371/journal.pone.0136505. eCollection 2015.

13.

Deregulation of miR-183 and KIAA0101 in Aggressive and Malignant Pituitary Tumors.

Roche M, Wierinckx A, Croze S, Rey C, Legras-Lachuer C, Morel AP, Fusco A, Raverot G, Trouillas J, Lachuer J.

Front Med (Lausanne). 2015 Aug 10;2:54. doi: 10.3389/fmed.2015.00054. eCollection 2015.

14.

Defective NK Cells in Acute Myeloid Leukemia Patients at Diagnosis Are Associated with Blast Transcriptional Signatures of Immune Evasion.

Khaznadar Z, Boissel N, Agaugué S, Henry G, Cheok M, Vignon M, Geromin D, Cayuela JM, Castaigne S, Pautas C, Raffoux E, Lachuer J, Sigaux F, Preudhomme C, Dombret H, Dulphy N, Toubert A.

J Immunol. 2015 Sep 15;195(6):2580-90. doi: 10.4049/jimmunol.1500262. Epub 2015 Aug 5.

15.

Multiparameter Phase I trials: a tool for model-based development of targeted agent combinations--example of EVESOR trial.

El-Madani M, Hénin E, Lefort T, Tod M, Freyer G, Cassier P, Valette PJ, Rodriguez-Lafrasse C, Berger F, Guitton J, Lachuer J, Slimane K, Barrois C, You B.

Future Oncol. 2015;11(10):1511-8. doi: 10.2217/fon.15.49.

PMID:
25963428
16.

Alterations of the RRAS and ERCC1 genes at 19q13 in gemistocytic astrocytomas.

Ohta T, Kim YH, Oh JE, Satomi K, Nonoguchi N, Keyvani K, Pierscianek D, Sure U, Mittelbronn M, Paulus W, Vital A, Yokoo H, McDonald K, Kleihues P, Nazaret N, Barbet F, Lachuer J, Ohgaki H.

J Neuropathol Exp Neurol. 2014 Oct;73(10):908-15. doi: 10.1097/NEN.0000000000000110.

PMID:
25192052
17.

Mir-23b and miR-130b expression is downregulated in pituitary adenomas.

Leone V, Langella C, D'Angelo D, Mussnich P, Wierinckx A, Terracciano L, Raverot G, Lachuer J, Rotondi S, Jaffrain-Rea ML, Trouillas J, Fusco A.

Mol Cell Endocrinol. 2014 Jun 5;390(1-2):1-7. doi: 10.1016/j.mce.2014.03.002. Epub 2014 Mar 28.

PMID:
24681352
18.

Snail family members unequally trigger EMT and thereby differ in their ability to promote the neoplastic transformation of mammary epithelial cells.

Gras B, Jacqueroud L, Wierinckx A, Lamblot C, Fauvet F, Lachuer J, Puisieux A, Ansieau S.

PLoS One. 2014 Mar 17;9(3):e92254. doi: 10.1371/journal.pone.0092254. eCollection 2014.

19.

Detection and genetic characterization of Seoul virus from commensal brown rats in France.

Dupinay T, Pounder KC, Ayral F, Laaberki MH, Marston DA, Lacôte S, Rey C, Barbet F, Voller K, Nazaret N, Artois M, Marianneau P, Lachuer J, Fooks AR, Pépin M, Legras-Lachuer C, McElhinney LM.

Virol J. 2014 Feb 20;11:32. doi: 10.1186/1743-422X-11-32.

20.

A switch in the expression of embryonic EMT-inducers drives the development of malignant melanoma.

Caramel J, Papadogeorgakis E, Hill L, Browne GJ, Richard G, Wierinckx A, Saldanha G, Osborne J, Hutchinson P, Tse G, Lachuer J, Puisieux A, Pringle JH, Ansieau S, Tulchinsky E.

Cancer Cell. 2013 Oct 14;24(4):466-80. doi: 10.1016/j.ccr.2013.08.018. Epub 2013 Sep 26.

21.
22.

BRCA1-Dependent Translational Regulation in Breast Cancer Cells.

Dacheux E, Vincent A, Nazaret N, Combet C, Wierinckx A, Mazoyer S, Diaz JJ, Lachuer J, Venezia ND.

PLoS One. 2013 Jun 21;8(6):e67313. doi: 10.1371/journal.pone.0067313. Print 2013.

23.

Tailored HIV-1 vectors for genetic modification of primary human dendritic cells and monocytes.

Durand S, Nguyen XN, Turpin J, Cordeil S, Nazaret N, Croze S, Mahieux R, Lachuer J, Legras-Lachuer C, Cimarelli A.

J Virol. 2013 Jan;87(1):234-42. doi: 10.1128/JVI.01459-12. Epub 2012 Oct 17.

24.

Nonstructural Nipah virus C protein regulates both the early host proinflammatory response and viral virulence.

Mathieu C, Guillaume V, Volchkova VA, Pohl C, Jacquot F, Looi RY, Wong KT, Legras-Lachuer C, Volchkov VE, Lachuer J, Horvat B.

J Virol. 2012 Oct;86(19):10766-75. doi: 10.1128/JVI.01203-12. Epub 2012 Jul 25.

25.

EMT inducers catalyze malignant transformation of mammary epithelial cells and drive tumorigenesis towards claudin-low tumors in transgenic mice.

Morel AP, Hinkal GW, Thomas C, Fauvet F, Courtois-Cox S, Wierinckx A, Devouassoux-Shisheboran M, Treilleux I, Tissier A, Gras B, Pourchet J, Puisieux I, Browne GJ, Spicer DB, Lachuer J, Ansieau S, Puisieux A.

PLoS Genet. 2012;8(5):e1002723. doi: 10.1371/journal.pgen.1002723. Epub 2012 May 24.

26.

Amplification of the STOML3, FREM2, and LHFP genes is associated with mesenchymal differentiation in gliosarcoma.

Nagaishi M, Kim YH, Mittelbronn M, Giangaspero F, Paulus W, Brokinkel B, Vital A, Tanaka Y, Nakazato Y, Legras-Lachuer C, Lachuer J, Ohgaki H.

Am J Pathol. 2012 May;180(5):1816-23. doi: 10.1016/j.ajpath.2012.01.027.

PMID:
22538188
27.

Mmi1 RNA surveillance machinery directs RNAi complex RITS to specific meiotic genes in fission yeast.

Hiriart E, Vavasseur A, Touat-Todeschini L, Yamashita A, Gilquin B, Lambert E, Perot J, Shichino Y, Nazaret N, Boyault C, Lachuer J, Perazza D, Yamamoto M, Verdel A.

EMBO J. 2012 May 16;31(10):2296-308. doi: 10.1038/emboj.2012.105. Epub 2012 Apr 20.

28.

Preferential binding of the methyl-CpG binding domain protein 2 at methylated transcriptional start site regions.

Chatagnon A, Perriaud L, Nazaret N, Croze S, Benhattar J, Lachuer J, Dante R.

Epigenetics. 2011 Nov;6(11):1295-307. doi: 10.4161/epi.6.11.17875. Epub 2011 Nov 1.

PMID:
22048253
29.

Differential effect of oxidative or excitotoxic stress on the transcriptional profile of amyotrophic lateral sclerosis-linked mutant SOD1 cultured neurons.

Boutahar N, Wierinckx A, Camdessanche JP, Antoine JC, Reynaud E, Lassabliere F, Lachuer J, Borg J.

J Neurosci Res. 2011 Sep;89(9):1439-50. doi: 10.1002/jnr.22672. Epub 2011 Jun 6.

PMID:
21647936
30.

Alterations in the RB1 pathway in low-grade diffuse gliomas lacking common genetic alterations.

Kim YH, Lachuer J, Mittelbronn M, Paulus W, Brokinkel B, Keyvani K, Sure U, Wrede K, Nobusawa S, Nakazato Y, Tanaka Y, Vital A, Mariani L, Ohgaki H.

Brain Pathol. 2011 Nov;21(6):645-51. doi: 10.1111/j.1750-3639.2011.00492.x. Epub 2011 May 30.

PMID:
21470325
31.

CCN5, a novel transcriptional repressor of the transforming growth factor β signaling pathway.

Sabbah M, Prunier C, Ferrand N, Megalophonos V, Lambein K, De Wever O, Nazaret N, Lachuer J, Dumont S, Redeuilh G.

Mol Cell Biol. 2011 Apr;31(7):1459-69. doi: 10.1128/MCB.01316-10. Epub 2011 Jan 24.

32.

Integrated genomic profiling identifies loss of chromosome 11p impacting transcriptomic activity in aggressive pituitary PRL tumors.

Wierinckx A, Roche M, Raverot G, Legras-Lachuer C, Croze S, Nazaret N, Rey C, Auger C, Jouanneau E, Chanson P, Trouillas J, Lachuer J.

Brain Pathol. 2011 Sep;21(5):533-43. doi: 10.1111/j.1750-3639.2011.00476.x. Epub 2011 Feb 23.

PMID:
21251114
33.

Gene expression profiles of human melanoma cells with different invasive potential reveal TSPAN8 as a novel mediator of invasion.

Berthier-Vergnes O, El Kharbili M, de la Fouchardière A, Pointecouteau T, Verrando P, Wierinckx A, Lachuer J, Le Naour F, Lamartine J.

Br J Cancer. 2011 Jan 4;104(1):155-65. doi: 10.1038/sj.bjc.6605994. Epub 2010 Nov 16.

34.

Clonal expansion of HTLV-1 positive CD8+ cells relies on cIAP-2 but not on c-FLIP expression.

Zane L, Sibon D, Legras C, Lachuer J, Wierinckx A, Mehlen P, Delfau-Larue MH, Gessain A, Gout O, Pinatel C, Lançon A, Mortreux F, Wattel E.

Virology. 2010 Nov 25;407(2):341-51. doi: 10.1016/j.virol.2010.07.023. Epub 2010 Sep 22.

35.

Intratumoral patterns of genomic imbalance in glioblastomas.

Nobusawa S, Lachuer J, Wierinckx A, Kim YH, Huang J, Legras C, Kleihues P, Ohgaki H.

Brain Pathol. 2010 Sep;20(5):936-44. doi: 10.1111/j.1750-3639.2010.00395.x. Epub 2010 Mar 18.

PMID:
20406234
36.

Clinical, hormonal and molecular characterization of pituitary ACTH adenomas without (silent corticotroph adenomas) and with Cushing's disease.

Raverot G, Wierinckx A, Jouanneau E, Auger C, Borson-Chazot F, Lachuer J, Pugeat M, Trouillas J.

Eur J Endocrinol. 2010 Jul;163(1):35-43. doi: 10.1530/EJE-10-0076. Epub 2010 Apr 12.

PMID:
20385723
37.

Proliferation markers of human pituitary tumors: contribution of a genome-wide transcriptome approach.

Wierinckx A, Raverot G, Nazaret N, Jouanneau E, Auger C, Lachuer J, Trouillas J.

Mol Cell Endocrinol. 2010 Sep 15;326(1-2):30-9. doi: 10.1016/j.mce.2010.02.043. Epub 2010 Mar 6.

PMID:
20211685
38.

Prognostic factors in prolactin pituitary tumors: clinical, histological, and molecular data from a series of 94 patients with a long postoperative follow-up.

Raverot G, Wierinckx A, Dantony E, Auger C, Chapas G, Villeneuve L, Brue T, Figarella-Branger D, Roy P, Jouanneau E, Jan M, Lachuer J, Trouillas J; HYPOPRONOS.

J Clin Endocrinol Metab. 2010 Apr;95(4):1708-16. doi: 10.1210/jc.2009-1191. Epub 2010 Feb 17.

PMID:
20164287
39.

The extract of Ginkgo biloba EGb 761 reactivates a juvenile profile in the skeletal muscle of sarcopenic rats by transcriptional reprogramming.

Bidon C, Lachuer J, Molgó J, Wierinckx A, de la Porte S, Pignol B, Christen Y, Meloni R, Koenig H, Biguet NF, Mallet J.

PLoS One. 2009 Nov 24;4(11):e7998. doi: 10.1371/journal.pone.0007998.

40.

Genome-wide expression analyses establish dendritic cells as a new osteoclast precursor able to generate bone-resorbing cells more efficiently than monocytes.

Gallois A, Lachuer J, Yvert G, Wierinckx A, Brunet F, Rabourdin-Combe C, Delprat C, Jurdic P, Mazzorana M.

J Bone Miner Res. 2010 Mar;25(3):661-72. doi: 10.1359/jbmr.090829.

41.

Overexpression of transcription factor Sp1 leads to gene expression perturbations and cell cycle inhibition.

Deniaud E, Baguet J, Chalard R, Blanquier B, Brinza L, Meunier J, Michallet MC, Laugraud A, Ah-Soon C, Wierinckx A, Castellazzi M, Lachuer J, Gautier C, Marvel J, Leverrier Y.

PLoS One. 2009 Sep 15;4(9):e7035. doi: 10.1371/journal.pone.0007035.

42.

Specific association between the methyl-CpG-binding domain protein 2 and the hypermethylated region of the human telomerase reverse transcriptase promoter in cancer cells.

Chatagnon A, Bougel S, Perriaud L, Lachuer J, Benhattar J, Dante R.

Carcinogenesis. 2009 Jan;30(1):28-34. doi: 10.1093/carcin/bgn240. Epub 2008 Oct 24.

PMID:
18952593
43.

Proteomic analysis of autocrine/paracrine effects of human growth hormone in human mammary carcinoma cells.

Vouyovitch CM, Vidal L, Borges S, Raccurt M, Arnould C, Chiesa J, Lobie PE, Lachuer J, Mertani HC.

Adv Exp Med Biol. 2008;617:493-500. doi: 10.1007/978-0-387-69080-3_49.

PMID:
18497074
44.

Gene expression profiling in brain following acute systemic hypertonicity: novel genes possibly involved in osmoadaptation.

Maallem S, Wierinckx A, Lachuer J, Kwon MH, Tappaz ML.

J Neurochem. 2008 May;105(4):1198-211. doi: 10.1111/j.1471-4159.2008.05222.x. Epub 2008 Jan 10.

45.

Developmental plasticity of the carotid chemoafferent pathway in rats that are hypoxic during the prenatal period.

Peyronnet J, Roux JC, Mamet J, Perrin D, Lachuer J, Pequignot JM, Dalmaz Y.

Eur J Neurosci. 2007 Nov;26(10):2865-72.

46.

A diagnostic marker set for invasion, proliferation, and aggressiveness of prolactin pituitary tumors.

Wierinckx A, Auger C, Devauchelle P, Reynaud A, Chevallier P, Jan M, Perrin G, Fèvre-Montange M, Rey C, Figarella-Branger D, Raverot G, Belin MF, Lachuer J, Trouillas J.

Endocr Relat Cancer. 2007 Sep;14(3):887-900.

PMID:
17914117
47.

[DNA microarray technology: principles and applications to the study of neurological disorders].

Ducray F, Honnorat J, Lachuer J.

Rev Neurol (Paris). 2007 Apr;163(4):409-20. Review. French.

PMID:
17452943
48.

Gene expression profiling in insulinomas of Men1 beta-cell mutant mice reveals early genetic and epigenetic events involved in pancreatic beta-cell tumorigenesis.

Fontanière S, Tost J, Wierinckx A, Lachuer J, Lu J, Hussein N, Busato F, Gut I, Wang ZQ, Zhang CX.

Endocr Relat Cancer. 2006 Dec;13(4):1223-36.

PMID:
17158767
49.

Microarray analysis reveals differential gene expression patterns in tumors of the pineal region.

Fèvre-Montange M, Champier J, Szathmari A, Wierinckx A, Mottolese C, Guyotat J, Figarella-Branger D, Jouvet A, Lachuer J.

J Neuropathol Exp Neurol. 2006 Jul;65(7):675-84.

PMID:
16825954
50.

Gene expression profiling reveals an inflammatory process in the anx/anx mutant mice.

Lachuer J, Ouyang L, Legras C, Del Rio J, Barlow C.

Brain Res Mol Brain Res. 2005 Oct 3;139(2):372-6.

PMID:
16006007

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