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Items: 37

1.

eXpression2Kinases (X2K) Web: linking expression signatures to upstream cell signaling networks.

Clarke DJB, Kuleshov MV, Schilder BM, Torre D, Duffy ME, Keenan AB, Lachmann A, Feldmann AS, Gundersen GW, Silverstein MC, Wang Z, Ma'ayan A.

Nucleic Acids Res. 2018 May 25. doi: 10.1093/nar/gky458. [Epub ahead of print]

PMID:
29800326
2.

Integration of protein phosphorylation, acetylation, and methylation data sets to outline lung cancer signaling networks.

Grimes M, Hall B, Foltz L, Levy T, Rikova K, Gaiser J, Cook W, Smirnova E, Wheeler T, Clark NR, Lachmann A, Zhang B, Hornbeck P, Ma'ayan A, Comb M.

Sci Signal. 2018 May 22;11(531). pii: eaaq1087. doi: 10.1126/scisignal.aaq1087.

PMID:
29789295
3.

Massive mining of publicly available RNA-seq data from human and mouse.

Lachmann A, Torre D, Keenan AB, Jagodnik KM, Lee HJ, Wang L, Silverstein MC, Ma'ayan A.

Nat Commun. 2018 Apr 10;9(1):1366. doi: 10.1038/s41467-018-03751-6.

4.

Datasets2Tools, repository and search engine for bioinformatics datasets, tools and canned analyses.

Torre D, Krawczuk P, Jagodnik KM, Lachmann A, Wang Z, Wang L, Kuleshov MV, Ma'ayan A.

Sci Data. 2018 Feb 27;5:180023. doi: 10.1038/sdata.2018.23.

5.

L1000FWD: fireworks visualization of drug-induced transcriptomic signatures.

Wang Z, Lachmann A, Keenan AB, Ma'ayan A.

Bioinformatics. 2018 Jun 15;34(12):2150-2152. doi: 10.1093/bioinformatics/bty060.

PMID:
29420694
6.

The Library of Integrated Network-Based Cellular Signatures NIH Program: System-Level Cataloging of Human Cells Response to Perturbations.

Keenan AB, Jenkins SL, Jagodnik KM, Koplev S, He E, Torre D, Wang Z, Dohlman AB, Silverstein MC, Lachmann A, Kuleshov MV, Ma'ayan A, Stathias V, Terryn R, Cooper D, Forlin M, Koleti A, Vidovic D, Chung C, Schürer SC, Vasiliauskas J, Pilarczyk M, Shamsaei B, Fazel M, Ren Y, Niu W, Clark NA, White S, Mahi N, Zhang L, Kouril M, Reichard JF, Sivaganesan S, Medvedovic M, Meller J, Koch RJ, Birtwistle MR, Iyengar R, Sobie EA, Azeloglu EU, Kaye J, Osterloh J, Haston K, Kalra J, Finkbiener S, Li J, Milani P, Adam M, Escalante-Chong R, Sachs K, Lenail A, Ramamoorthy D, Fraenkel E, Daigle G, Hussain U, Coye A, Rothstein J, Sareen D, Ornelas L, Banuelos M, Mandefro B, Ho R, Svendsen CN, Lim RG, Stocksdale J, Casale MS, Thompson TG, Wu J, Thompson LM, Dardov V, Venkatraman V, Matlock A, Van Eyk JE, Jaffe JD, Papanastasiou M, Subramanian A, Golub TR, Erickson SD, Fallahi-Sichani M, Hafner M, Gray NS, Lin JR, Mills CE, Muhlich JL, Niepel M, Shamu CE, Williams EH, Wrobel D, Sorger PK, Heiser LM, Gray JW, Korkola JE, Mills GB, LaBarge M, Feiler HS, Dane MA, Bucher E, Nederlof M, Sudar D, Gross S, Kilburn DF, Smith R, Devlin K, Margolis R, Derr L, Lee A, Pillai A.

Cell Syst. 2018 Jan 24;6(1):13-24. doi: 10.1016/j.cels.2017.11.001. Epub 2017 Nov 29. Review.

PMID:
29199020
7.

Systematic, network-based characterization of therapeutic target inhibitors.

Shen Y, Alvarez MJ, Bisikirska B, Lachmann A, Realubit R, Pampou S, Coku J, Karan C, Califano A.

PLoS Comput Biol. 2017 Oct 12;13(10):e1005599. doi: 10.1371/journal.pcbi.1005599. eCollection 2017 Oct.

8.

Polycomb repressive complex 2 (PRC2) silences genes responsible for neurodegeneration.

von Schimmelmann M, Feinberg PA, Sullivan JM, Ku SM, Badimon A, Duff MK, Wang Z, Lachmann A, Dewell S, Ma'ayan A, Han MH, Tarakhovsky A, Schaefer A.

Nat Neurosci. 2016 Oct;19(10):1321-30. doi: 10.1038/nn.4360. Epub 2016 Aug 15.

9.

Functional characterization of somatic mutations in cancer using network-based inference of protein activity.

Alvarez MJ, Shen Y, Giorgi FM, Lachmann A, Ding BB, Ye BH, Califano A.

Nat Genet. 2016 Aug;48(8):838-47. doi: 10.1038/ng.3593. Epub 2016 Jun 20.

10.

Detection and removal of spatial bias in multiwell assays.

Lachmann A, Giorgi FM, Alvarez MJ, Califano A.

Bioinformatics. 2016 Jul 1;32(13):1959-65. doi: 10.1093/bioinformatics/btw092. Epub 2016 Feb 28.

PMID:
27153732
11.

ARACNe-AP: gene network reverse engineering through adaptive partitioning inference of mutual information.

Lachmann A, Giorgi FM, Lopez G, Califano A.

Bioinformatics. 2016 Jul 15;32(14):2233-5. doi: 10.1093/bioinformatics/btw216. Epub 2016 Apr 23.

12.

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update.

Kuleshov MV, Jones MR, Rouillard AD, Fernandez NF, Duan Q, Wang Z, Koplev S, Jenkins SL, Jagodnik KM, Lachmann A, McDermott MG, Monteiro CD, Gundersen GW, Ma'ayan A.

Nucleic Acids Res. 2016 Jul 8;44(W1):W90-7. doi: 10.1093/nar/gkw377. Epub 2016 May 3.

13.

Receptor heteromerization expands the repertoire of cannabinoid signaling in rodent neurons.

Rozenfeld R, Bushlin I, Gomes I, Tzavaras N, Gupta A, Neves S, Battini L, Gusella GL, Lachmann A, Ma'ayan A, Blitzer RD, Devi LA.

PLoS One. 2012;7(1):e29239. doi: 10.1371/journal.pone.0029239. Epub 2012 Jan 3.

14.

FNV: light-weight flash-based network and pathway viewer.

Dannenfelser R, Lachmann A, Szenk M, Ma'ayan A.

Bioinformatics. 2011 Apr 15;27(8):1181-2. doi: 10.1093/bioinformatics/btr098. Epub 2011 Feb 23.

15.

ChEA: transcription factor regulation inferred from integrating genome-wide ChIP-X experiments.

Lachmann A, Xu H, Krishnan J, Berger SI, Mazloom AR, Ma'ayan A.

Bioinformatics. 2010 Oct 1;26(19):2438-44. doi: 10.1093/bioinformatics/btq466. Epub 2010 Aug 13.

16.

Global phosphorylation analysis of beta-arrestin-mediated signaling downstream of a seven transmembrane receptor (7TMR).

Xiao K, Sun J, Kim J, Rajagopal S, Zhai B, Villén J, Haas W, Kovacs JJ, Shukla AK, Hara MR, Hernandez M, Lachmann A, Zhao S, Lin Y, Cheng Y, Mizuno K, Ma'ayan A, Gygi SP, Lefkowitz RJ.

Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15299-304. doi: 10.1073/pnas.1008461107. Epub 2010 Aug 4. Erratum in: Proc Natl Acad Sci U S A. 2012 Aug 14;109(33):13464.

17.

Lists2Networks: integrated analysis of gene/protein lists.

Lachmann A, Ma'ayan A.

BMC Bioinformatics. 2010 Feb 12;11:87. doi: 10.1186/1471-2105-11-87.

18.

Inferring the Sign of Kinase-Substrate Interactions by Combining Quantitative Phosphoproteomics with a Literature-Based Mammalian Kinome Network.

Hernandez M, Lachmann A, Zhao S, Xiao K, Ma'ayan A.

Proc IEEE Int Symp Bioinformatics Bioeng. 2010;2010:180-184.

19.

Systems-level dynamic analyses of fate change in murine embryonic stem cells.

Lu R, Markowetz F, Unwin RD, Leek JT, Airoldi EM, MacArthur BD, Lachmann A, Rozov R, Ma'ayan A, Boyer LA, Troyanskaya OG, Whetton AD, Lemischka IR.

Nature. 2009 Nov 19;462(7271):358-62. doi: 10.1038/nature08575.

20.

GATE: software for the analysis and visualization of high-dimensional time series expression data.

MacArthur BD, Lachmann A, Lemischka IR, Ma'ayan A.

Bioinformatics. 2010 Jan 1;26(1):143-4. doi: 10.1093/bioinformatics/btp628. Epub 2009 Nov 5.

21.

KEA: kinase enrichment analysis.

Lachmann A, Ma'ayan A.

Bioinformatics. 2009 Mar 1;25(5):684-6. doi: 10.1093/bioinformatics/btp026. Epub 2009 Jan 28.

22.

The effects of racemic D,L-methadone and L-methadone in substituted patients--a randomized controlled study.

Verthein U, Ullmann R, Lachmann A, Düring A, Koch B, Meyer-Thompson HG, Schmidt R, Reimer J, Haasen C.

Drug Alcohol Depend. 2005 Nov 1;80(2):267-71.

PMID:
15916866
23.

[SF-36 Health Survey in Rehabilitation Research. Findings from the North German Network for Rehabilitation Research, NVRF, within the rehabilitation research funding program].

Bullinger M, Morfeld M, Kohlmann T, Nantke J, van den Bussche H, Dodt B, Dunkelberg S, Kirchberger I, Krüger-Bödecker A, Lachmann A, Lang K, Mathis C, Mittag O, Peters A, Raspe HH, Schulz H.

Rehabilitation (Stuttg). 2003 Aug;42(4):218-25. German.

PMID:
12938044
24.

[The opinion of general practitioners in East and west Germany on rehabilitation].

Dunkelberg S, Lachmann A, Van Den Bussche H, Müller K.

Gesundheitswesen. 2002 Jun;64(6):369-74. German.

PMID:
12063649
25.

Filiform polyposis of the colon in chronic inflammatory bowel disease (so-called giant inflammatory polyps).

Bauknecht KJ, Grosse G, Kleinert J, Lachmann A, Niedobitek F.

Z Gastroenterol. 2000 Oct;38(10):845-6, 848-54. Review.

PMID:
11089270
26.

Perioperative infection prophylaxis and risk factor impact in colon surgery.

Rau HG, Mittelkötter U, Zimmermann A, Lachmann A, Köhler L, Kullmann KH.

Chemotherapy. 2000 Sep-Oct;46(5):353-63.

PMID:
10965101
27.

[Need for rehabilitation from the viewpoint of the general practitioner].

Lachmann A, van den Bussche H, Dunkelberg S, Ehrhardt M.

Rehabilitation (Stuttg). 1999 Dec;38 Suppl 2:S148-53. German.

PMID:
10652713
28.

Ebb tide and undertow: discussion of following Sybil.

Lachmann A, Lachmann FM.

Psychoanal Rev. 1998 Dec;85(6):837-40. No abstract available.

PMID:
10226307
29.

[Letter: Acute fatal chloroquine poisoning].

Lachmann A.

Ugeskr Laeger. 1974 Jul 22;136(30):1692. Danish. No abstract available.

PMID:
4428511
30.

[MATERNAL AND CHILD CARE IN THE CONGO].

LACHMANN A.

Ugeskr Laeger. 1964 Jul 2;126:951-7. Danish. No abstract available.

PMID:
14176768
31.

[Congo 1961. Experiences and adventures of a Red Cross physician in the Congo].

LACHMANN A.

Ugeskr Laeger. 1962 May 11;124:731-5. Danish. No abstract available.

PMID:
14461378
32.

[Meprobamate administration during labor].

LACHMANN A.

Geburtshilfe Frauenheilkd. 1958 Apr;18(4):387-9. German. No abstract available.

PMID:
13548414
33.

Severe refractory anaemia in pregnancy.

LACHMANN A, LUND E, VINTHERPAULSEN N.

Acta Obstet Gynecol Scand. 1954;33(4):395-404. No abstract available.

PMID:
14375883
34.

[Transverse presentation].

LACHMANN A.

Nord Med. 1953 Nov 5;50(45):1535-7. Undetermined Language. No abstract available.

PMID:
13111583
35.

[Infant mortality in transverse presentation].

Sørensen B, Lachmann A.

Nord Med. 1953 Jan 30;49(5):185-6. Undetermined Language. No abstract available.

PMID:
13054993
36.

[Retroflexion of the uterus].

LACHMANN A, JEPSEN O.

Ugeskr Laeger. 1950 Mar 9;112(10):330-2. Undetermined Language. No abstract available.

PMID:
15418652
37.

Metrorrhagi efter klimakteriet som følge af hormonproducerende ovarietumorer.

LACHMANN A.

Ugeskr Laeger. 1948 Apr 8;110(15):436-8. Undetermined Language. No abstract available.

PMID:
18864811

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