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Items: 45

1.

Genomic analyses in african populations identify novel risk loci for cleft palate.

Butali A, Mossey PA, Adeyemo WL, Eshete MA, Gowans LJJ, Busch TD, Jain D, Yu W, Huan L, Laurie CA, Laurie CC, Nelson S, Li M, Sanchez-Lara PA, Magee WP 3rd, Magee KS, Auslander A, Brindopke F, Kay DM, Caggana M, Romitti PA, Mills JL, Audu R, Onwuamah C, Oseni GO, Owais A, James O, Olaitan PB, Aregbesola BS, Braimah RO, Oginni FO, Oladele AO, Bello SA, Rhodes J, Shiang R, Donkor P, Obiri-Yeboah S, Arthur FKN, Twumasi P, Agbenorku P, Plange-Rhule G, Oti AA, Ogunlewe OM, Oladega AA, Adekunle AA, Erinoso AO, Adamson OO, Elufowoju AA, Ayelomi OI, Hailu T, Hailu A, Demissie Y, Derebew M, Eliason S, Romero-Bustillous M, Lo C, Park J, Desai S, Mohammed M, Abate F, Abdur-Rahman LO, Anand D, Saadi I, Oladugba AV, Lachke SA, Amendt BA, Rotimi CN, Marazita ML, Cornell RA, Murray JC, Adeyemo AA.

Hum Mol Genet. 2018 Nov 19. doi: 10.1093/hmg/ddy402. [Epub ahead of print]

PMID:
30452639
2.

RNA sequencing-based transcriptomic profiles of embryonic lens development for cataract gene discovery.

Anand D, Kakrana A, Siddam AD, Huang H, Saadi I, Lachke SA.

Hum Genet. 2018 Dec;137(11-12):941-954. doi: 10.1007/s00439-018-1958-0. Epub 2018 Nov 11.

PMID:
30417254
3.

Mutations in the Epithelial Cadherin-p120-Catenin Complex Cause Mendelian Non-Syndromic Cleft Lip with or without Cleft Palate.

Cox LL, Cox TC, Moreno Uribe LM, Zhu Y, Richter CT, Nidey N, Standley JM, Deng M, Blue E, Chong JX, Yang Y, Carstens RP, Anand D, Lachke SA, Smith JD, Dorschner MO, Bedell B, Kirk E, Hing AV, Venselaar H, Valencia-Ramirez LC, Bamshad MJ, Glass IA, Cooper JA, Haan E, Nickerson DA, van Bokhoven H, Zhou H, Krahn KN, Buckley MF, Murray JC, Lidral AC, Roscioli T.

Am J Hum Genet. 2018 Jun 7;102(6):1143-1157. doi: 10.1016/j.ajhg.2018.04.009. Epub 2018 May 24.

4.

Correction to: A zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans.

Krall M, Htun S, Anand D, Hart D, Lachke SA, Slavotinek AM.

Hum Genet. 2018 May;137(5):427-428. doi: 10.1007/s00439-018-1890-3.

PMID:
29752539
5.

A zebrafish model of foxe3 deficiency demonstrates lens and eye defects with dysregulation of key genes involved in cataract formation in humans.

Krall M, Htun S, Anand D, Hart D, Lachke SA, Slavotinek AM.

Hum Genet. 2018 Apr;137(4):315-328. doi: 10.1007/s00439-018-1884-1. Epub 2018 Apr 30. Erratum in: Hum Genet. 2018 May 11;:.

PMID:
29713869
6.

The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development.

Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Méreau A, Viet J, Gross JM, Paillard L, Lachke SA.

PLoS Genet. 2018 Mar 22;14(3):e1007278. doi: 10.1371/journal.pgen.1007278. eCollection 2018 Mar.

7.

Express: A database of transcriptome profiles encompassing known and novel transcripts across multiple development stages in eye tissues.

Budak G, Dash S, Srivastava R, Lachke SA, Janga SC.

Exp Eye Res. 2018 Mar;168:57-68. doi: 10.1016/j.exer.2018.01.009. Epub 2018 Jan 11.

PMID:
29337142
8.

Mutation update of transcription factor genes FOXE3, HSF4, MAF, and PITX3 causing cataracts and other developmental ocular defects.

Anand D, Agrawal SA, Slavotinek A, Lachke SA.

Hum Mutat. 2018 Apr;39(4):471-494. doi: 10.1002/humu.23395. Epub 2018 Jan 16.

PMID:
29314435
9.

iSyTE 2.0: a database for expression-based gene discovery in the eye.

Kakrana A, Yang A, Anand D, Djordjevic D, Ramachandruni D, Singh A, Huang H, Ho JWK, Lachke SA.

Nucleic Acids Res. 2018 Jan 4;46(D1):D875-D885. doi: 10.1093/nar/gkx837.

10.

Transcriptome analysis of developing lens reveals abundance of novel transcripts and extensive splicing alterations.

Srivastava R, Budak G, Dash S, Lachke SA, Janga SC.

Sci Rep. 2017 Sep 14;7(1):11572. doi: 10.1038/s41598-017-10615-4.

11.

β1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis.

Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK.

Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922. doi: 10.1167/iovs.17-21721.

12.

N-myc regulates growth and fiber cell differentiation in lens development.

Cavalheiro GR, Matos-Rodrigues GE, Zhao Y, Gomes AL, Anand D, Predes D, de Lima S, Abreu JG, Zheng D, Lachke SA, Cvekl A, Martins RAP.

Dev Biol. 2017 Sep 1;429(1):105-117. doi: 10.1016/j.ydbio.2017.07.002. Epub 2017 Jul 14.

13.

Exome sequencing provides additional evidence for the involvement of ARHGAP29 in Mendelian orofacial clefting and extends the phenotypic spectrum to isolated cleft palate.

Liu H, Busch T, Eliason S, Anand D, Bullard S, Gowans LJJ, Nidey N, Petrin A, Augustine-Akpan EA, Saadi I, Dunnwald M, Lachke SA, Zhu Y, Adeyemo A, Amendt B, Roscioli T, Cornell R, Murray J, Butali A.

Birth Defects Res. 2017 Jan 20;109(1):27-37. doi: 10.1002/bdra.23596.

14.

Novel phenotypes and loci identified through clinical genomics approaches to pediatric cataract.

Patel N, Anand D, Monies D, Maddirevula S, Khan AO, Algoufi T, Alowain M, Faqeih E, Alshammari M, Qudair A, Alsharif H, Aljubran F, Alsaif HS, Ibrahim N, Abdulwahab FM, Hashem M, Alsedairy H, Aldahmesh MA, Lachke SA, Alkuraya FS.

Hum Genet. 2017 Feb;136(2):205-225. doi: 10.1007/s00439-016-1747-6. Epub 2016 Nov 22.

15.

RNA-binding proteins in eye development and disease: implication of conserved RNA granule components.

Dash S, Siddam AD, Barnum CE, Janga SC, Lachke SA.

Wiley Interdiscip Rev RNA. 2016 Jul;7(4):527-57. doi: 10.1002/wrna.1355. Epub 2016 May 1. Review.

16.

Systems biology of lens development: A paradigm for disease gene discovery in the eye.

Anand D, Lachke SA.

Exp Eye Res. 2017 Mar;156:22-33. doi: 10.1016/j.exer.2016.03.010. Epub 2016 Mar 16. Review.

17.

Crim1 regulates integrin signaling in murine lens development.

Zhang Y, Fan J, Ho JW, Hu T, Kneeland SC, Fan X, Xi Q, Sellarole MA, de Vries WN, Lu W, Lachke SA, Lang RA, John SW, Maas RL.

Development. 2016 Jan 15;143(2):356-66. doi: 10.1242/dev.125591. Epub 2015 Dec 17.

18.

Prox1 and fibroblast growth factor receptors form a novel regulatory loop controlling lens fiber differentiation and gene expression.

Audette DS, Anand D, So T, Rubenstein TB, Lachke SA, Lovicu FJ, Duncan MK.

Development. 2016 Jan 15;143(2):318-28. doi: 10.1242/dev.127860. Epub 2015 Dec 10.

19.

An integrative approach to analyze microarray datasets for prioritization of genes relevant to lens biology and disease.

Anand D, Agrawal S, Siddam A, Motohashi H, Yamamoto M, Lachke SA.

Genom Data. 2015 Aug 1;5:223-227.

20.

Deficiency of the RNA binding protein caprin2 causes lens defects and features of Peters anomaly.

Dash S, Dang CA, Beebe DC, Lachke SA.

Dev Dyn. 2015 Oct;244(10):1313-27. doi: 10.1002/dvdy.24303. Epub 2015 Aug 7.

21.

Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract.

Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, Lachke SA.

Hum Genet. 2015 Jul;134(7):717-35. doi: 10.1007/s00439-015-1554-5. Epub 2015 Apr 21.

22.

Molecular characterization of mouse lens epithelial cell lines and their suitability to study RNA granules and cataract associated genes.

Terrell AM, Anand D, Smith SF, Dang CA, Waters SM, Pathania M, Beebe DC, Lachke SA.

Exp Eye Res. 2015 Feb;131:42-55. doi: 10.1016/j.exer.2014.12.011. Epub 2014 Dec 19.

23.

Pax6- and Six3-mediated induction of lens cell fate in mouse and human ES cells.

Anchan RM, Lachke SA, Gerami-Naini B, Lindsey J, Ng N, Naber C, Nickerson M, Cavallesco R, Rowan S, Eaton JL, Xi Q, Maas RL.

PLoS One. 2014 Dec 17;9(12):e115106. doi: 10.1371/journal.pone.0115106. eCollection 2014.

24.
25.

Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development.

Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK.

Mech Dev. 2014 Feb;131:86-110. doi: 10.1016/j.mod.2013.09.005. Epub 2013 Oct 23.

26.

Histone posttranslational modifications and cell fate determination: lens induction requires the lysine acetyltransferases CBP and p300.

Wolf L, Harrison W, Huang J, Xie Q, Xiao N, Sun J, Kong L, Lachke SA, Kuracha MR, Govindarajan V, Brindle PK, Ashery-Padan R, Beebe DC, Overbeek PA, Cvekl A.

Nucleic Acids Res. 2013 Dec;41(22):10199-214. doi: 10.1093/nar/gkt824. Epub 2013 Sep 12.

27.

Toward a systems-level understanding of the Hedgehog signaling pathway: defining the complex, robust, and fragile.

Tran PV, Lachke SA, Stottmann RW.

Wiley Interdiscip Rev Syst Biol Med. 2013 Jan-Feb;5(1):83-100. doi: 10.1002/wsbm.1193. Epub 2012 Oct 11. Review.

PMID:
23060005
28.

An evolutionarily conserved enhancer regulates Bmp4 expression in developing incisor and limb bud.

Jumlongras D, Lachke SA, O'Connell DJ, Aboukhalil A, Li X, Choe SE, Ho JW, Turbe-Doan A, Robertson EA, Olsen BR, Bulyk ML, Amendt BA, Maas RL.

PLoS One. 2012;7(6):e38568. doi: 10.1371/journal.pone.0038568. Epub 2012 Jun 12.

29.

iSyTE: integrated Systems Tool for Eye gene discovery.

Lachke SA, Ho JW, Kryukov GV, O'Connell DJ, Aboukhalil A, Bulyk ML, Park PJ, Maas RL.

Invest Ophthalmol Vis Sci. 2012 Mar 21;53(3):1617-27. doi: 10.1167/iovs.11-8839. Print 2012 Mar.

30.

RNA Granules and Cataract.

Lachke SA, Maas RL.

Expert Rev Ophthalmol. 2011 Oct 1;6(5):497-500. No abstract available.

31.

The cell adhesion gene PVRL3 is associated with congenital ocular defects.

Lachke SA, Higgins AW, Inagaki M, Saadi I, Xi Q, Long M, Quade BJ, Talkowski ME, Gusella JF, Fujimoto A, Robinson ML, Yang Y, Duong QT, Shapira I, Motro B, Miyoshi J, Takai Y, Morton CC, Maas RL.

Hum Genet. 2012 Feb;131(2):235-50. doi: 10.1007/s00439-011-1064-z. Epub 2011 Jul 17.

32.

Roles of the 15-kDa selenoprotein (Sep15) in redox homeostasis and cataract development revealed by the analysis of Sep 15 knockout mice.

Kasaikina MV, Fomenko DE, Labunskyy VM, Lachke SA, Qiu W, Moncaster JA, Zhang J, Wojnarowicz MW Jr, Natarajan SK, Malinouski M, Schweizer U, Tsuji PA, Carlson BA, Maas RL, Lou MF, Goldstein LE, Hatfield DL, Gladyshev VN.

J Biol Chem. 2011 Sep 23;286(38):33203-12. doi: 10.1074/jbc.M111.259218. Epub 2011 Jul 18.

33.

Mutations in the RNA granule component TDRD7 cause cataract and glaucoma.

Lachke SA, Alkuraya FS, Kneeland SC, Ohn T, Aboukhalil A, Howell GR, Saadi I, Cavallesco R, Yue Y, Tsai AC, Nair KS, Cosma MI, Smith RS, Hodges E, Alfadhli SM, Al-Hajeri A, Shamseldin HE, Behbehani A, Hannon GJ, Bulyk ML, Drack AV, Anderson PJ, John SW, Maas RL.

Science. 2011 Mar 25;331(6024):1571-6. doi: 10.1126/science.1195970.

34.

Building the developmental oculome: systems biology in vertebrate eye development and disease.

Lachke SA, Maas RL.

Wiley Interdiscip Rev Syst Biol Med. 2010 May-Jun;2(3):305-323. doi: 10.1002/wsbm.59. Review.

35.

Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity.

Rowan S, Siggers T, Lachke SA, Yue Y, Bulyk ML, Maas RL.

Genes Dev. 2010 May 15;24(10):980-5. doi: 10.1101/gad.1890410. Epub 2010 Apr 22.

36.

Investigation of eight candidate genes on chromosome 1p36 for autosomal dominant total congenital cataract.

Burdon KP, Hattersley K, Lachke SA, Laurie KJ, Maas RL, Mackey DA, Craig JE.

Mol Vis. 2008;14:1799-804. Epub 2008 Sep 30.

37.

Lens induction in vertebrates: variations on a conserved theme of signaling events.

Donner AL, Lachke SA, Maas RL.

Semin Cell Dev Biol. 2006 Dec;17(6):676-85. Epub 2006 Oct 27. Review.

PMID:
17164096
38.

Phenotypic switching and mating type switching of Candida glabrata at sites of colonization.

Brockert PJ, Lachke SA, Srikantha T, Pujol C, Galask R, Soll DR.

Infect Immun. 2003 Dec;71(12):7109-18.

39.

Skin facilitates Candida albicans mating.

Lachke SA, Lockhart SR, Daniels KJ, Soll DR.

Infect Immun. 2003 Sep;71(9):4970-6.

40.

Three mating type-like loci in Candida glabrata.

Srikantha T, Lachke SA, Soll DR.

Eukaryot Cell. 2003 Apr;2(2):328-40.

41.
42.

Phenotypic switching and filamentation in Candida glabrata.

Lachke SA, Joly S, Daniels K, Soll DR.

Microbiology. 2002 Sep;148(Pt 9):2661-74.

PMID:
12213913
43.
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