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Items: 10


Differential muscle hypertrophy is associated with satellite cell numbers and Akt pathway activation following activin type IIB receptor inhibition in Mtm1 p.R69C mice.

Lawlor MW, Viola MG, Meng H, Edelstein RV, Liu F, Yan K, Luna EJ, Lerch-Gaggl A, Hoffmann RG, Pierson CR, Buj-Bello A, Lachey JL, Pearsall S, Yang L, Hillard CJ, Beggs AH.

Am J Pathol. 2014 Jun;184(6):1831-42. doi: 10.1016/j.ajpath.2014.03.003. Epub 2014 Apr 13.


Inhibition of activin receptor type IIB increases strength and lifespan in myotubularin-deficient mice.

Lawlor MW, Read BP, Edelstein R, Yang N, Pierson CR, Stein MJ, Wermer-Colan A, Buj-Bello A, Lachey JL, Seehra JS, Beggs AH.

Am J Pathol. 2011 Feb;178(2):784-93. doi: 10.1016/j.ajpath.2010.10.035. Erratum in: Am J Pathol. 2011 Mar;178(3):1406.


Administration of a soluble activin type IIB receptor promotes skeletal muscle growth independent of fiber type.

Cadena SM, Tomkinson KN, Monnell TE, Spaits MS, Kumar R, Underwood KW, Pearsall RS, Lachey JL.

J Appl Physiol (1985). 2010 Sep;109(3):635-42. doi: 10.1152/japplphysiol.00866.2009. Epub 2010 May 13.


Leptin targets in the mouse brain.

Scott MM, Lachey JL, Sternson SM, Lee CE, Elias CF, Friedman JM, Elmquist JK.

J Comp Neurol. 2009 Jun 10;514(5):518-32. doi: 10.1002/cne.22025.


A soluble activin type IIB receptor improves function in a mouse model of amyotrophic lateral sclerosis.

Morrison BM, Lachey JL, Warsing LC, Ting BL, Pullen AE, Underwood KW, Kumar R, Sako D, Grinberg A, Wong V, Colantuoni E, Seehra JS, Wagner KR.

Exp Neurol. 2009 Jun;217(2):258-68. doi: 10.1016/j.expneurol.2009.02.017. Epub 2009 Mar 11.


Mice lacking ghrelin receptors resist the development of diet-induced obesity.

Zigman JM, Nakano Y, Coppari R, Balthasar N, Marcus JN, Lee CE, Jones JE, Deysher AE, Waxman AR, White RD, Williams TD, Lachey JL, Seeley RJ, Lowell BB, Elmquist JK.

J Clin Invest. 2005 Dec;115(12):3564-72.


Serotonergic pathways converge upon central melanocortin systems to regulate energy balance.

Zhou L, Williams T, Lachey JL, Kishi T, Cowley MA, Heisler LK.

Peptides. 2005 Oct;26(10):1728-32. Review.


The role of central glucagon-like peptide-1 in mediating the effects of visceral illness: differential effects in rats and mice.

Lachey JL, D'Alessio DA, Rinaman L, Elmquist JK, Drucker DJ, Seeley RJ.

Endocrinology. 2005 Jan;146(1):458-62. Epub 2004 Sep 30.


Cloned mice have an obese phenotype not transmitted to their offspring.

Tamashiro KL, Wakayama T, Akutsu H, Yamazaki Y, Lachey JL, Wortman MD, Seeley RJ, D'Alessio DA, Woods SC, Yanagimachi R, Sakai RR.

Nat Med. 2002 Mar;8(3):262-7.


A novel selective melanocortin-4 receptor agonist reduces food intake in rats and mice without producing aversive consequences.

Benoit SC, Schwartz MW, Lachey JL, Hagan MM, Rushing PA, Blake KA, Yagaloff KA, Kurylko G, Franco L, Danhoo W, Seeley RJ.

J Neurosci. 2000 May 1;20(9):3442-8.

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