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Items: 10


GM-CSF- and IRF4-Dependent Signaling Can Regulate Myeloid Cell Numbers and the Macrophage Phenotype during Inflammation.

Lee MC, Lacey DC, Fleetwood AJ, Achuthan A, Hamilton JA, Cook AD.

J Immunol. 2019 May 15;202(10):3033-3040. doi: 10.4049/jimmunol.1801549. Epub 2019 Apr 15.


TNF and granulocyte macrophage-colony stimulating factor interdependence mediates inflammation via CCL17.

Cook AD, Lee MC, Saleh R, Khiew HW, Christensen AD, Achuthan A, Fleetwood AJ, Lacey DC, Smith JE, Förster I, Hamilton JA.

JCI Insight. 2018 Mar 22;3(6). pii: 99249. doi: 10.1172/jci.insight.99249.


Granulocyte macrophage colony-stimulating factor induces CCL17 production via IRF4 to mediate inflammation.

Achuthan A, Cook AD, Lee MC, Saleh R, Khiew HW, Chang MW, Louis C, Fleetwood AJ, Lacey DC, Christensen AD, Frye AT, Lam PY, Kusano H, Nomura K, Steiner N, Förster I, Nutt SL, Olshansky M, Turner SJ, Hamilton JA.

J Clin Invest. 2016 Sep 1;126(9):3453-66. doi: 10.1172/JCI87828. Epub 2016 Aug 15.


Hypoxia enhances the proliferative response of macrophages to CSF-1 and their pro-survival response to TNF.

Hamilton JA, Lacey DC, Turner A, de Kok B, Huynh J, Scholz GM.

PLoS One. 2012;7(9):e45853. doi: 10.1371/journal.pone.0045853. Epub 2012 Sep 19.


Granulocyte-macrophage colony-stimulating factor is a key mediator in experimental osteoarthritis pain and disease development.

Cook AD, Pobjoy J, Steidl S, Dürr M, Braine EL, Turner AL, Lacey DC, Hamilton JA.

Arthritis Res Ther. 2012 Sep 20;14(5):R199. doi: 10.1186/ar4037.


Granulocyte-macrophage colony-stimulating factor is a key mediator in inflammatory and arthritic pain.

Cook AD, Pobjoy J, Sarros S, Steidl S, Dürr M, Lacey DC, Hamilton JA.

Ann Rheum Dis. 2013 Feb;72(2):265-70. doi: 10.1136/annrheumdis-2012-201703. Epub 2012 Jul 24.


Defining GM-CSF- and macrophage-CSF-dependent macrophage responses by in vitro models.

Lacey DC, Achuthan A, Fleetwood AJ, Dinh H, Roiniotis J, Scholz GM, Chang MW, Beckman SK, Cook AD, Hamilton JA.

J Immunol. 2012 Jun 1;188(11):5752-65. doi: 10.4049/jimmunol.1103426. Epub 2012 Apr 30.


Extracellular proteomes of M-CSF (CSF-1) and GM-CSF-dependent macrophages.

Bailey MJ, Lacey DC, de Kok BV, Veith PD, Reynolds EC, Hamilton JA.

Immunol Cell Biol. 2011 Feb;89(2):283-93. doi: 10.1038/icb.2010.92. Epub 2010 Jul 27.


Low dose metal particles can induce monocyte/macrophage survival.

Lacey DC, De Kok B, Clanchy FI, Bailey MJ, Speed K, Haynes D, Graves SE, Hamilton JA.

J Orthop Res. 2009 Nov;27(11):1481-6. doi: 10.1002/jor.20914.


Proinflammatory cytokines inhibit osteogenic differentiation from stem cells: implications for bone repair during inflammation.

Lacey DC, Simmons PJ, Graves SE, Hamilton JA.

Osteoarthritis Cartilage. 2009 Jun;17(6):735-42. doi: 10.1016/j.joca.2008.11.011. Epub 2008 Nov 24.

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