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Items: 35

1.

PD-1 signaling affects cristae morphology and leads to mitochondrial dysfunction in human CD8+ T lymphocytes.

Ogando J, Sáez ME, Santos J, Nuevo-Tapioles C, Gut M, Esteve-Codina A, Heath S, González-Pérez A, Cuezva JM, Lacalle RA, Mañes S.

J Immunother Cancer. 2019 Jun 13;7(1):151. doi: 10.1186/s40425-019-0628-7.

2.

SOD3 improves the tumor response to chemotherapy by stabilizing endothelial HIF-2α.

Mira E, Carmona-Rodríguez L, Pérez-Villamil B, Casas J, Fernández-Aceñero MJ, Martínez-Rey D, Martín-González P, Heras-Murillo I, Paz-Cabezas M, Tardáguila M, Oury TD, Martín-Puig S, Lacalle RA, Fabriás G, Díaz-Rubio E, Mañes S.

Nat Commun. 2018 Feb 8;9(1):575. doi: 10.1038/s41467-018-03079-1.

3.

Chemokine Receptor Signaling and the Hallmarks of Cancer.

Lacalle RA, Blanco R, Carmona-Rodríguez L, Martín-Leal A, Mira E, Mañes S.

Int Rev Cell Mol Biol. 2017;331:181-244. doi: 10.1016/bs.ircmb.2016.09.011. Epub 2016 Nov 30. Review.

PMID:
28325212
4.

Type I phosphatidylinositol 4-phosphate 5-kinase homo- and heterodimerization determines its membrane localization and activity.

Lacalle RA, de Karam JC, Martínez-Muñoz L, Artetxe I, Peregil RM, Sot J, Rojas AM, Goñi FM, Mellado M, Mañes S.

FASEB J. 2015 Jun;29(6):2371-85. doi: 10.1096/fj.14-264606. Epub 2015 Feb 24.

PMID:
25713054
5.

An isoform-specific PDZ-binding motif targets type I PIP5 kinase beta to the uropod and controls polarization of neutrophil-like HL60 cells.

Mañes S, Fuentes G, Peregil RM, Rojas AM, Lacalle RA.

FASEB J. 2010 Sep;24(9):3381-92. doi: 10.1096/fj.09-153106. Epub 2010 May 4.

PMID:
20442317
6.

Type I phosphatidylinositol 4-phosphate 5-kinase controls neutrophil polarity and directional movement.

Lacalle RA, Peregil RM, Albar JP, Merino E, Martínez-A C, Mérida I, Mañes S.

J Cell Biol. 2007 Dec 31;179(7):1539-53. Epub 2007 Dec 24.

7.

Orchestration of lymphocyte chemotaxis by mitochondrial dynamics.

Campello S, Lacalle RA, Bettella M, Mañes S, Scorrano L, Viola A.

J Exp Med. 2006 Dec 25;203(13):2879-86. Epub 2006 Dec 4.

8.

Mastering time and space: immune cell polarization and chemotaxis.

Mañes S, Gómez-Moutón C, Lacalle RA, Jiménez-Baranda S, Mira E, Martínez-A C.

Semin Immunol. 2005 Feb;17(1):77-86. Review.

PMID:
15582490
9.

PTEN regulates motility but not directionality during leukocyte chemotaxis.

Lacalle RA, Gómez-Moutón C, Barber DF, Jiménez-Baranda S, Mira E, Martínez-A C, Carrera AC, Mañes S.

J Cell Sci. 2004 Dec 1;117(Pt 25):6207-15.

10.

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing.

Nombela-Arrieta C, Lacalle RA, Montoya MC, Kunisaki Y, Megías D, Marqués M, Carrera AC, Mañes S, Fukui Y, Martínez-A C, Stein JV.

Immunity. 2004 Sep;21(3):429-41.

11.

Statins inhibit HIV-1 infection by down-regulating Rho activity.

del Real G, Jiménez-Baranda S, Mira E, Lacalle RA, Lucas P, Gómez-Moutón C, Alegret M, Peña JM, Rodríguez-Zapata M, Alvarez-Mon M, Martínez-A C, Mañes S.

J Exp Med. 2004 Aug 16;200(4):541-7.

12.

Secreted MMP9 promotes angiogenesis more efficiently than constitutive active MMP9 bound to the tumor cell surface.

Mira E, Lacalle RA, Buesa JM, de Buitrago GG, Jiménez-Baranda S, Gómez-Moutón C, Martínez-A C, Mañes S.

J Cell Sci. 2004 Apr 1;117(Pt 9):1847-57.

13.

Dynamic redistribution of raft domains as an organizing platform for signaling during cell chemotaxis.

Gómez-Moutón C, Lacalle RA, Mira E, Jiménez-Baranda S, Barber DF, Carrera AC, Martínez-A C, Mañes S.

J Cell Biol. 2004 Mar 1;164(5):759-68. Epub 2004 Feb 23.

14.

CCR5 expression influences the progression of human breast cancer in a p53-dependent manner.

Mañes S, Mira E, Colomer R, Montero S, Real LM, Gómez-Moutón C, Jiménez-Baranda S, Garzón A, Lacalle RA, Harshman K, Ruíz A, Martínez-A C.

J Exp Med. 2003 Nov 3;198(9):1381-9.

15.

Blocking of HIV-1 infection by targeting CD4 to nonraft membrane domains.

Del Real G, Jiménez-Baranda S, Lacalle RA, Mira E, Lucas P, Gómez-Moutón C, Carrera AC, Martínez-A C, Mañes S.

J Exp Med. 2002 Aug 5;196(3):293-301.

16.

Quantitative determination of tumor cell intravasation in a real-time polymerase chain reaction-based assay.

Mira E, Lacalle RA, Gómez-Moutón C, Leonardo E, Mañes S.

Clin Exp Metastasis. 2002;19(4):313-8.

PMID:
12090471
17.

Specific SHP-2 partitioning in raft domains triggers integrin-mediated signaling via Rho activation.

Lacalle RA, Mira E, Gomez-Mouton C, Jimenez-Baranda S, Martinez-A C, Manes S.

J Cell Biol. 2002 Apr 15;157(2):277-89. Epub 2002 Apr 15.

18.

Segregation of leading-edge and uropod components into specific lipid rafts during T cell polarization.

Gómez-Móuton C, Abad JL, Mira E, Lacalle RA, Gallardo E, Jiménez-Baranda S, Illa I, Bernad A, Mañes S, Martínez-A C.

Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9642-7. Epub 2001 Aug 7.

19.

Membrane raft microdomains in chemokine receptor function.

Mañes S, Lacalle RA, Gómez-Moutón C, del Real G, Mira E, Martínez-A C.

Semin Immunol. 2001 Apr;13(2):147-57. Review.

PMID:
11308298
20.

Membrane raft microdomains mediate lateral assemblies required for HIV-1 infection.

Mañes S, del Real G, Lacalle RA, Lucas P, Gómez-Moutón C, Sánchez-Palomino S, Delgado R, Alcamí J, Mira E, Martínez-A C.

EMBO Rep. 2000 Aug;1(2):190-6.

21.

A role for chemokine receptor transactivation in growth factor signaling.

Mira E, Lacalle RA, González MA, Gómez-Moutón C, Abad JL, Bernad A, Martínez-A C, Mañes S.

EMBO Rep. 2001 Feb;2(2):151-6.

22.

Cells on the move: a dialogue between polarization and motility.

Mañes S, Mira E, Gómez-Moutón C, Lacalle RA, Martínez C.

IUBMB Life. 2000 Feb;49(2):89-96. Review.

23.

Membrane raft microdomains mediate front-rear polarity in migrating cells.

Mañes S, Mira E, Gómez-Moutón C, Lacalle RA, Keller P, Labrador JP, Martínez-A C.

EMBO J. 1999 Nov 15;18(22):6211-20.

24.

Insulin-like growth factor I-triggered cell migration and invasion are mediated by matrix metalloproteinase-9.

Mira E, Mañes S, Lacalle RA, Márquez G, Martínez-A C.

Endocrinology. 1999 Apr;140(4):1657-64.

PMID:
10098500
25.

Concerted activity of tyrosine phosphatase SHP-2 and focal adhesion kinase in regulation of cell motility.

Mañes S, Mira E, Gómez-Mouton C, Zhao ZJ, Lacalle RA, Martínez-A C.

Mol Cell Biol. 1999 Apr;19(4):3125-35.

26.

The matrix metalloproteinase-9 regulates the insulin-like growth factor-triggered autocrine response in DU-145 carcinoma cells.

Mañes S, Llorente M, Lacalle RA, Gómez-Moutón C, Kremer L, Mira E, Martínez-A C.

J Biol Chem. 1999 Mar 12;274(11):6935-45.

27.
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31.

Cosmid pJAR4, a novel Streptomyces-Escherichia coli shuttle vector for the cloning of Streptomyces operons.

Tercero JA, Lacalle RA, Jiménez A.

FEMS Microbiol Lett. 1992 Sep 15;75(2-3):203-6.

PMID:
1398037
33.
34.

Molecular analysis of the pac gene encoding a puromycin N-acetyl transferase from Streptomyces alboniger.

Lacalle RA, Pulido D, Vara J, Zalacaín M, Jiménez A.

Gene. 1989 Jul 15;79(2):375-80.

PMID:
2676728
35.

Two genes in Streptomyces alboniger puromycin biosynthesis pathway are closely linked.

Vara JA, Pulido D, Lacalle RA, Jiménez A.

Gene. 1988 Sep 15;69(1):135-40.

PMID:
3066696

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