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Enhancing Stability and Reducing Viscosity of a Monoclonal Antibody With Cosolutes by Weakening Protein-Protein Interactions.

Dear BJ, Hung JJ, Laber JR, Wilks LR, Sharma A, Truskett TM, Johnston KP.

J Pharm Sci. 2019 Aug;108(8):2517-2526. doi: 10.1016/j.xphs.2019.03.008. Epub 2019 Mar 15.


Charge Shielding Prevents Aggregation of Supercharged GFP Variants at High Protein Concentration.

Laber JR, Dear BJ, Martins ML, Jackson DE, DiVenere A, Gollihar JD, Ellington AD, Truskett TM, Johnston KP, Maynard JA.

Mol Pharm. 2017 Oct 2;14(10):3269-3280. doi: 10.1021/acs.molpharmaceut.7b00322. Epub 2017 Sep 18.


A cocktail of humanized anti-pertussis toxin antibodies limits disease in murine and baboon models of whooping cough.

Nguyen AW, Wagner EK, Laber JR, Goodfield LL, Smallridge WE, Harvill ET, Papin JF, Wolf RF, Padlan EA, Bristol A, Kaleko M, Maynard JA.

Sci Transl Med. 2015 Dec 2;7(316):316ra195. doi: 10.1126/scitranslmed.aad0966.

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