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Items: 30

1.

The small-molecule compound AC-73 targeting CD147 inhibits leukemic cell proliferation, induces autophagy and increases the chemotherapeutic sensitivity of acute myeloid leukemia cells.

Spinello I, Saulle E, Quaranta MT, Pasquini L, Pelosi E, Castelli G, Ottone T, Voso MT, Testa U, Labbaye C.

Haematologica. 2019 May;104(5):973-985. doi: 10.3324/haematol.2018.199661. Epub 2018 Nov 22.

2.

miR-146 and miR-155: Two Key Modulators of Immune Response and Tumor Development.

Testa U, Pelosi E, Castelli G, Labbaye C.

Noncoding RNA. 2017 Jun 26;3(3). pii: E22. doi: 10.3390/ncrna3030022. Review.

3.

Identification of β-Dystrobrevin as a Direct Target of miR-143: Involvement in Early Stages of Neural Differentiation.

Quaranta MT, Spinello I, Paolillo R, Macchia G, Boe A, Ceccarini M, Labbaye C, Macioce P.

PLoS One. 2016 May 25;11(5):e0156325. doi: 10.1371/journal.pone.0156325. eCollection 2016.

4.

Oxidative stress and hypoxia in normal and leukemic stem cells.

Testa U, Labbaye C, Castelli G, Pelosi E.

Exp Hematol. 2016 Jul;44(7):540-60. doi: 10.1016/j.exphem.2016.04.012. Epub 2016 May 12. Review.

PMID:
27179622
5.

Differential hypoxic regulation of the microRNA-146a/CXCR4 pathway in normal and leukemic monocytic cells: impact on response to chemotherapy.

Spinello I, Quaranta MT, Paolillo R, Pelosi E, Cerio AM, Saulle E, Lo Coco F, Testa U, Labbaye C.

Haematologica. 2015 Sep;100(9):1160-71. doi: 10.3324/haematol.2014.120295. Epub 2015 Jun 4.

6.

Human TM9SF4 Is a New Gene Down-Regulated by Hypoxia and Involved in Cell Adhesion of Leukemic Cells.

Paolillo R, Spinello I, Quaranta MT, Pasquini L, Pelosi E, Lo Coco F, Testa U, Labbaye C.

PLoS One. 2015 May 11;10(5):e0126968. doi: 10.1371/journal.pone.0126968. eCollection 2015.

7.

miR-146a controls CXCR4 expression in a pathway that involves PLZF and can be used to inhibit HIV-1 infection of CD4(+) T lymphocytes.

Quaranta MT, Olivetta E, Sanchez M, Spinello I, Paolillo R, Arenaccio C, Federico M, Labbaye C.

Virology. 2015 Apr;478:27-38. doi: 10.1016/j.virol.2015.01.016. Epub 2015 Feb 21.

8.

The HIV protease inhibitor indinavir down-regulates the expression of the pro-angiogenic MT1-MMP by human endothelial cells.

Barillari G, Iovane A, Bacigalupo I, Labbaye C, Chiozzini C, Sernicola L, Quaranta MT, Falchi M, Sgadari C, Ensoli B.

Angiogenesis. 2014 Oct;17(4):831-8. doi: 10.1007/s10456-014-9430-9. Epub 2014 Apr 10.

PMID:
24719186
9.

MicroRNA-146a and AMD3100, two ways to control CXCR4 expression in acute myeloid leukemias.

Spinello I, Quaranta MT, Riccioni R, Riti V, Pasquini L, Boe A, Pelosi E, Vitale A, Foà R, Testa U, Labbaye C.

Blood Cancer J. 2011 Jun;1(6):e26. doi: 10.1038/bcj.2011.24. Epub 2011 Jun 24.

10.

The emerging role of MIR-146A in the control of hematopoiesis, immune function and cancer.

Labbaye C, Testa U.

J Hematol Oncol. 2012 Mar 27;5:13. doi: 10.1186/1756-8722-5-13. Review.

11.

CDDO-Im is a stimulator of megakaryocytic differentiation.

Petronelli A, Pelosi E, Santoro S, Saulle E, Cerio AM, Mariani G, Labbaye C, Testa U.

Leuk Res. 2011 Apr;35(4):534-44. doi: 10.1016/j.leukres.2010.09.013. Epub 2010 Oct 29.

PMID:
21035854
12.

The interaction with HMG20a/b proteins suggests a potential role for beta-dystrobrevin in neuronal differentiation.

Artegiani B, Labbaye C, Sferra A, Quaranta MT, Torreri P, Macchia G, Ceccarini M, Petrucci TC, Macioce P.

J Biol Chem. 2010 Aug 6;285(32):24740-50. doi: 10.1074/jbc.M109.090654. Epub 2010 Jun 8.

13.

MicroRNAs in normal and malignant myelopoiesis.

Pelosi E, Labbaye C, Testa U.

Leuk Res. 2009 Dec;33(12):1584-93. doi: 10.1016/j.leukres.2009.04.039. Epub 2009 May 30. Review.

PMID:
19482355
14.

PLZF-mediated control on c-kit expression in CD34(+) cells and early erythropoiesis.

Spinello I, Quaranta MT, Pasquini L, Pelosi E, Petrucci E, Pagliuca A, Castelli G, Mariani G, Diverio D, Foà R, Testa U, Labbaye C.

Oncogene. 2009 Jun 11;28(23):2276-88. doi: 10.1038/onc.2009.87. Epub 2009 May 4.

PMID:
19421145
15.

The miR-15a-miR-16-1 cluster controls prostate cancer by targeting multiple oncogenic activities.

Bonci D, Coppola V, Musumeci M, Addario A, Giuffrida R, Memeo L, D'Urso L, Pagliuca A, Biffoni M, Labbaye C, Bartucci M, Muto G, Peschle C, De Maria R.

Nat Med. 2008 Nov;14(11):1271-7. doi: 10.1038/nm.1880. Epub 2008 Oct 19.

PMID:
18931683
16.

A three-step pathway comprising PLZF/miR-146a/CXCR4 controls megakaryopoiesis.

Labbaye C, Spinello I, Quaranta MT, Pelosi E, Pasquini L, Petrucci E, Biffoni M, Nuzzolo ER, Billi M, Foà R, Brunetti E, Grignani F, Testa U, Peschle C.

Nat Cell Biol. 2008 Jul;10(7):788-801. doi: 10.1038/ncb1741. Epub 2008 Jun 22.

PMID:
18568019
17.

PLZF-mediated control on VLA-4 expression in normal and leukemic myeloid cells.

Quaranta MT, Spinello I, Testa U, Mariani G, Diverio D, Foà R, Peschle C, Labbaye C.

Oncogene. 2006 Jan 19;25(3):399-408.

PMID:
16158049
18.

Role of PLZF in melanoma progression.

Felicetti F, Bottero L, Felli N, Mattia G, Labbaye C, Alvino E, Peschle C, Colombo MP, Carè A.

Oncogene. 2004 Jun 3;23(26):4567-76.

PMID:
15077196
19.

PLZF induces megakaryocytic development, activates Tpo receptor expression and interacts with GATA1 protein.

Labbaye C, Quaranta MT, Pagliuca A, Militi S, Licht JD, Testa U, Peschle C.

Oncogene. 2002 Sep 26;21(43):6669-79.

20.

Expression and role of PML gene in normal adult hematopoiesis: functional interaction between PML and Rb proteins in erythropoiesis.

Labbaye C, Valtieri M, Grignani F, Puglisi R, Luchetti L, Masella B, Alcalay M, Testa U, Peschle C.

Oncogene. 1999 Jun 10;18(23):3529-40.

21.

Secondary leukemia responsive to retinoic acid with abnormal localization of RARalpha protein: a report of two cases.

Leone G, Sica S, Ortu La Barbera E, Testa U, Riccioni R, Labbaye C, Peschle C, Zollino M.

Blood. 1998 Jun 15;91(12):4811-2. No abstract available.

22.

Differential expression and functional role of GATA-2, NF-E2, and GATA-1 in normal adult hematopoiesis.

Labbaye C, Valtieri M, Barberi T, Meccia E, Masella B, Pelosi E, Condorelli GL, Testa U, Peschle C.

J Clin Invest. 1995 May;95(5):2346-58.

23.

Retinoic acid downmodulates erythroid differentiation and GATA1 expression in purified adult-progenitor culture.

Labbaye C, Valtieri M, Testa U, Giampaolo A, Meccia E, Sterpetti P, Parolini I, Pelosi E, Bulgarini D, Cayre YE, et al.

Blood. 1994 Feb 1;83(3):651-6.

24.

Regulation of myeloblastin messenger RNA expression in myeloid leukemia cells treated with all-trans retinoic acid.

Labbaye C, Zhang J, Casanova JL, Lanotte M, Teng J, Miller WH Jr, Cayre YE.

Blood. 1993 Jan 15;81(2):475-81.

25.

Wegener autoantigen and myeloblastin are encoded by a single mRNA.

Labbaye C, Musette P, Cayre YE.

Proc Natl Acad Sci U S A. 1991 Oct 15;88(20):9253-6.

26.

Wegener's autoantigen and leukemia.

Musette P, Labbaye C, Dorner MH, Cayre YE, Casanova JL, Kourilsky P.

Blood. 1991 Mar 15;77(6):1398-9. No abstract available.

27.

Antisense myb inhibition of purified erythroid progenitors in development and differentiation is linked to cycling activity and expression of DNA polymerase alpha.

Valtieri M, Venturelli D, Caré A, Fossati C, Pelosi E, Labbaye C, Mattia G, Gewirtz AM, Calabretta B, Peschle C.

Blood. 1991 Mar 15;77(6):1181-90.

28.

Molecular mechanisms underlying erythropoiesis: cycling activity of adult BFU-e relates to their requirement for c-myb function and potential for HbF synthesis.

Valtieri M, Gabbianelli M, Pelosi E, Testa U, Labbaye C, Mattia G, Fossati C, Venturelli D, Gewirtz AM, Calabretta B, et al.

Int J Cell Cloning. 1990 Jan;8 Suppl 1:314-34.

PMID:
1691249
29.

Reactivation of HbF synthesis in normal adult erythroid bursts by IL-3.

Gabbianelli M, Pelosi E, Labbaye C, Valtieri M, Testa U, Peschle C.

Br J Haematol. 1990 Jan;74(1):114-7.

PMID:
1690023
30.

Granulocyte-macrophage colony-stimulating factor reactivates fetal hemoglobin synthesis in erythroblast clones from normal adults.

Gabbianelli M, Pelosi E, Bassano E, Labbaye C, Petti S, Rocca E, Tritarelli E, Miller BA, Valtieri M, Testa U, et al.

Blood. 1989 Dec;74(8):2657-67.

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