Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 106


Cyclin A-cdk1-Dependent Phosphorylation of Bora Is the Triggering Factor Promoting Mitotic Entry.

Vigneron S, Sundermann L, Labbé JC, Pintard L, Radulescu O, Castro A, Lorca T.

Dev Cell. 2018 Jun 4;45(5):637-650.e7. doi: 10.1016/j.devcel.2018.05.005.


Spindle assembly checkpoint strength is linked to cell fate in the Caenorhabditis elegans embryo.

Gerhold AR, Poupart V, Labbé JC, Maddox PS.

Mol Biol Cell. 2018 Jun 15;29(12):1435-1448. doi: 10.1091/mbc.E18-04-0215. Epub 2018 Apr 24.


Actomyosin contractility regulators stabilize the cytoplasmic bridge between the two primordial germ cells during Caenorhabditis elegans embryogenesis.

Goupil E, Amini R, Hall DH, Labbé JC.

Mol Biol Cell. 2017 Dec 15;28(26):3789-3800. doi: 10.1091/mbc.E17-08-0502. Epub 2017 Oct 26.


Correction for Vigneron et al., "Characterization of the Mechanisms Controlling Greatwall Activity".

Vigneron S, Gharbi-Ayachi A, Raymond AA, Burgess A, Labbé JC, Labesse G, Monsarrat B, Lorca T, Castro A.

Mol Cell Biol. 2017 Jun 29;37(14). pii: e00231-17. doi: 10.1128/MCB.00231-17. Print 2017 Jul 15. No abstract available.


DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.

Narbonne P, Maddox PS, Labbé JC.

PLoS Genet. 2017 Apr 14;13(4):e1006738. doi: 10.1371/journal.pgen.1006738. eCollection 2017 Apr.


The master Greatwall kinase, a critical regulator of mitosis and meiosis.

Vigneron S, Robert P, Hached K, Sundermann L, Charrasse S, Labbé JC, Castro A, Lorca T.

Int J Dev Biol. 2016;60(7-8-9):245-254.


Bigger Isn't Always Better: Cell Size and the Spindle Assembly Checkpoint.

Gerhold AR, Labbé JC, Maddox PS.

Dev Cell. 2016 Feb 8;36(3):244-6. doi: 10.1016/j.devcel.2016.01.017.


DAF-18/PTEN locally antagonizes insulin signalling to couple germline stem cell proliferation to oocyte needs in C. elegans.

Narbonne P, Maddox PS, Labbé JC.

Development. 2015 Dec 15;142(24):4230-41. doi: 10.1242/dev.130252. Epub 2015 Nov 9.


Syncytium biogenesis: It's all about maintaining good connections.

Amini R, Chartier NT, Labbé JC.

Worm. 2015 Jan 28;4(1):e992665. doi: 10.4161/21624054.2014.992665. eCollection 2015 Jan-Mar.


Cell cycle timing regulation during asynchronous divisions of the early C. elegans embryo.

Tavernier N, Labbé JC, Pintard L.

Exp Cell Res. 2015 Oct 1;337(2):243-8. doi: 10.1016/j.yexcr.2015.07.022. Epub 2015 Jul 23. Review.


C. elegans Anillin proteins regulate intercellular bridge stability and germline syncytial organization.

Amini R, Goupil E, Labella S, Zetka M, Maddox AS, Labbé JC, Chartier NT.

J Cell Biol. 2015 May 11;209(3):467. doi: 10.1083/jcb.20131011704212015c. Epub 2015 May 4. No abstract available.


Investigating the regulation of stem and progenitor cell mitotic progression by in situ imaging.

Gerhold AR, Ryan J, Vallée-Trudeau JN, Dorn JF, Labbé JC, Maddox PS.

Curr Biol. 2015 May 4;25(9):1123-34. doi: 10.1016/j.cub.2015.02.054. Epub 2015 Mar 26.


CDK-1 and two B-type cyclins promote PAR-6 stabilization during polarization of the early C. elegans embryo.

Rabilotta A, Desrosiers M, Labbé JC.

PLoS One. 2015 Feb 6;10(2):e0117656. doi: 10.1371/journal.pone.0117656. eCollection 2015.


C. elegans Anillin proteins regulate intercellular bridge stability and germline syncytial organization.

Amini R, Goupil E, Labella S, Zetka M, Maddox AS, Labbé JC, Chartier NT.

J Cell Biol. 2014 Jul 7;206(1):129-43. doi: 10.1083/jcb.201310117. Epub 2014 Jun 30. Erratum in: J Cell Biol. 2015 May 11;209(3):467.


PAR-4/LKB1 regulates DNA replication during asynchronous division of the early C. elegans embryo.

Benkemoun L, Descoteaux C, Chartier NT, Pintard L, Labbé JC.

J Cell Biol. 2014 May 26;205(4):447-55. doi: 10.1083/jcb.201312029. Epub 2014 May 19.


The expanding roles of Gβγ subunits in G protein-coupled receptor signaling and drug action.

Khan SM, Sleno R, Gora S, Zylbergold P, Laverdure JP, Labbé JC, Miller GJ, Hébert TE.

Pharmacol Rev. 2013 Feb 13;65(2):545-77. doi: 10.1124/pr.111.005603. Print 2013 Apr. Review.


RhoA activation during polarization and cytokinesis of the early Caenorhabditis elegans embryo is differentially dependent on NOP-1 and CYK-4.

Tse YC, Werner M, Longhini KM, Labbe JC, Goldstein B, Glotzer M.

Mol Biol Cell. 2012 Oct;23(20):4020-31. doi: 10.1091/mbc.E12-04-0268. Epub 2012 Aug 23.


Live imaging for studying asymmetric cell division in the C. elegans embryo.

Rabilotta A, Amini R, Labbé JC.

Methods Mol Biol. 2012;916:111-25. doi: 10.1007/978-1-61779-980-8_9.


RAB-5 controls the cortical organization and dynamics of PAR proteins to maintain C. elegans early embryonic polarity.

Hyenne V, Tremblay-Boudreault T, Velmurugan R, Grant BD, Loerke D, Labbé JC.

PLoS One. 2012;7(4):e35286. doi: 10.1371/journal.pone.0035286. Epub 2012 Apr 24.


[Greatwall, a new guardian of mitosis].

Gharbi-Ayachi A, Burgess A, Vigneron S, Labbé JC, Castro A, Lorca T.

Med Sci (Paris). 2011 Apr;27(4):352-4. doi: 10.1051/medsci/2011274006. Epub 2011 Apr 28. French. No abstract available.


Characterization of the mechanisms controlling Greatwall activity.

Vigneron S, Gharbi-Ayachi A, Raymond AA, Burgess A, Labbé JC, Labesse G, Monsarrat B, Lorca T, Castro A.

Mol Cell Biol. 2011 Jun;31(11):2262-75. doi: 10.1128/MCB.00753-10. Epub 2011 Mar 28. Erratum in: Mol Cell Biol. 2017 Jun 29;37(14 ):.


PAR-4/LKB1 mobilizes nonmuscle myosin through anillin to regulate C. elegans embryonic polarization and cytokinesis.

Chartier NT, Salazar Ospina DP, Benkemoun L, Mayer M, Grill SW, Maddox AS, Labbé JC.

Curr Biol. 2011 Feb 22;21(4):259-69. doi: 10.1016/j.cub.2011.01.010. Epub 2011 Jan 27.


The substrate of Greatwall kinase, Arpp19, controls mitosis by inhibiting protein phosphatase 2A.

Gharbi-Ayachi A, Labbé JC, Burgess A, Vigneron S, Strub JM, Brioudes E, Van-Dorsselaer A, Castro A, Lorca T.

Science. 2010 Dec 17;330(6011):1673-7. doi: 10.1126/science.1197048.


Constant regulation of both the MPF amplification loop and the Greatwall-PP2A pathway is required for metaphase II arrest and correct entry into the first embryonic cell cycle.

Lorca T, Bernis C, Vigneron S, Burgess A, Brioudes E, Labbé JC, Castro A.

J Cell Sci. 2010 Jul 1;123(Pt 13):2281-91. doi: 10.1242/jcs.064527.


Loss of human Greatwall results in G2 arrest and multiple mitotic defects due to deregulation of the cyclin B-Cdc2/PP2A balance.

Burgess A, Vigneron S, Brioudes E, Labbé JC, Lorca T, Castro A.

Proc Natl Acad Sci U S A. 2010 Jul 13;107(28):12564-9. doi: 10.1073/pnas.0914191107. Epub 2010 Jun 10.


RSK2 is a kinetochore-associated protein that participates in the spindle assembly checkpoint.

Vigneron S, Brioudes E, Burgess A, Labbé JC, Lorca T, Castro A.

Oncogene. 2010 Jun 17;29(24):3566-74. doi: 10.1038/onc.2010.105. Epub 2010 Apr 12.


[Mechanisms of asymmetric cell division: from model organisms to tumorigenesis].

Chartier NT, Hyenne V, Labbé JC.

Med Sci (Paris). 2010 Mar;26(3):251-7. doi: 10.1051/medsci/2010263251. Review. French.


Understanding the role of asymmetric cell division in cancer using C. elegans.

Hyenne V, Chartier NT, Labbé JC.

Dev Dyn. 2010 May;239(5):1378-87. doi: 10.1002/dvdy.22237. Review.


Differential requirements for STRAD in LKB1-dependent functions in C. elegans.

Narbonne P, Hyenne V, Li S, Labbé JC, Roy R.

Development. 2010 Feb;137(4):661-70. doi: 10.1242/dev.042044.


Caenorhabditis elegans APN-1 plays a vital role in maintaining genome stability.

Zakaria C, Kassahun H, Yang X, Labbé JC, Nilsen H, Ramotar D.

DNA Repair (Amst). 2010 Feb 4;9(2):169-76. doi: 10.1016/j.dnarep.2009.11.007. Epub 2009 Dec 24.


MAP kinase signaling antagonizes PAR-1 function during polarization of the early Caenorhabditis elegans embryo.

Spilker AC, Rabilotta A, Zbinden C, Labbé JC, Gotta M.

Genetics. 2009 Nov;183(3):965-77. doi: 10.1534/genetics.109.106716. Epub 2009 Aug 31.


Greatwall maintains mitosis through regulation of PP2A.

Vigneron S, Brioudes E, Burgess A, Labbé JC, Lorca T, Castro A.

EMBO J. 2009 Sep 16;28(18):2786-93. doi: 10.1038/emboj.2009.228. Epub 2009 Aug 13.


C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division.

Hyenne V, Desrosiers M, Labbé JC.

Dev Biol. 2008 Sep 15;321(2):368-78. doi: 10.1016/j.ydbio.2008.06.037. Epub 2008 Jul 4.


Chfr interacts and colocalizes with TCTP to the mitotic spindle.

Burgess A, Labbé JC, Vigneron S, Bonneaud N, Strub JM, Van Dorsselaer A, Lorca T, Castro A.

Oncogene. 2008 Sep 18;27(42):5554-66. doi: 10.1038/onc.2008.167. Epub 2008 May 26.


Heterotrimeric G protein signaling functions with dynein to promote spindle positioning in C. elegans.

Couwenbergs C, Labbé JC, Goulding M, Marty T, Bowerman B, Gotta M.

J Cell Biol. 2007 Oct 8;179(1):15-22. Epub 2007 Oct 1.


Pin1 stabilizes Emi1 during G2 phase by preventing its association with SCF(betatrcp).

Bernis C, Vigneron S, Burgess A, Labbé JC, Fesquet D, Castro A, Lorca T.

EMBO Rep. 2007 Jan;8(1):91-8. Epub 2006 Dec 8.


Ubiquitin-mediated protein degradation in Xenopus egg extracts.

Castro A, Vigneron S, Bernis C, Labbé JC, Lorca T.

Methods Mol Biol. 2006;322:223-34. Review.


New developmental insights from high-throughput biological analysis in Caenorhabditis elegans.

Labbé JC, Roy R.

Clin Genet. 2006 Apr;69(4):306-14. Review.


The anaphase-promoting complex: a key factor in the regulation of cell cycle.

Castro A, Bernis C, Vigneron S, Labbé JC, Lorca T.

Oncogene. 2005 Jan 13;24(3):314-25. Review.


The forces that position a mitotic spindle asymmetrically are tethered until after the time of spindle assembly.

Labbé JC, McCarthy EK, Goldstein B.

J Cell Biol. 2004 Oct 25;167(2):245-56. Epub 2004 Oct 18.


Kinetochore localization of spindle checkpoint proteins: who controls whom?

Vigneron S, Prieto S, Bernis C, Labbé JC, Castro A, Lorca T.

Mol Biol Cell. 2004 Oct;15(10):4584-96. Epub 2004 Jul 21.


[Mitosis under control].

Castro A, Vigneron S, Lorca T, Labbé JC.

Med Sci (Paris). 2003 Mar;19(3):309-17. Review. French.


Xkid is degraded in a D-box, KEN-box, and A-box-independent pathway.

Castro A, Vigneron S, Bernis C, Labbé JC, Lorca T.

Mol Cell Biol. 2003 Jun;23(12):4126-38.


PAR proteins regulate microtubule dynamics at the cell cortex in C. elegans.

Labbé JC, Maddox PS, Salmon ED, Goldstein B.

Curr Biol. 2003 Apr 29;13(9):707-14.


The D-Box-activating domain (DAD) is a new proteolysis signal that stimulates the silent D-Box sequence of Aurora-A.

Castro A, Vigneron S, Bernis C, Labbé JC, Prigent C, Lorca T.

EMBO Rep. 2002 Dec;3(12):1209-14. Epub 2002 Nov 21.


Embryonic development: a new SPN on cell fate specification.

Labbé JC, Goldstein B.

Curr Biol. 2002 Jun 4;12(11):R396-8. Review.


Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1.

Peter M, Le Peuch C, Labbé JC, Meyer AN, Donoghue DJ, Dorée M.

EMBO Rep. 2002 Jun;3(6):551-6. Epub 2002 May 24.


APC/Fizzy-Related targets Aurora-A kinase for proteolysis.

Castro A, Arlot-Bonnemains Y, Vigneron S, Labbé JC, Prigent C, Lorca T.

EMBO Rep. 2002 May;3(5):457-62. Epub 2002 Apr 18.


A new role for Mos in Xenopus oocyte maturation: targeting Myt1 independently of MAPK.

Peter M, Labbé JC, Dorée M, Mandart E.

Development. 2002 May;129(9):2129-39.

Supplemental Content

Loading ...
Support Center