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Items: 16

1.

Thymic regulatory T cells arise via two distinct developmental programs.

Owen DL, Mahmud SA, Sjaastad LE, Williams JB, Spanier JA, Simeonov DR, Ruscher R, Huang W, Proekt I, Miller CN, Hekim C, Jeschke JC, Aggarwal P, Broeckel U, LaRue RS, Henzler CM, Alegre ML, Anderson MS, August A, Marson A, Zheng Y, Williams CB, Farrar MA.

Nat Immunol. 2019 Feb;20(2):195-205. doi: 10.1038/s41590-018-0289-6. Epub 2019 Jan 14.

2.

Sleeping Beauty Screen Identifies RREB1 and Other Genetic Drivers in Human B-cell Lymphoma.

Rahrmann EP, Wolf NK, Otto GM, Heltemes-Harris L, Ramsey LB, Shu J, LaRue RS, Linden MA, Rathe SK, Starr TK, Farrar MA, Moriarity BS, Largaespada DA.

Mol Cancer Res. 2019 Feb;17(2):567-582. doi: 10.1158/1541-7786.MCR-18-0582. Epub 2018 Oct 24.

PMID:
30355676
3.

Transcriptomic analysis of gene signatures associated with sickle pain.

Paul JA, Aich A, Abrahante JE, Wang Y, LaRue RS, Rathe SK, Kalland K, Mittal A, Jha R, Peng F, Largaespada DA, Bagchi A, Gupta K.

Sci Data. 2017 May 16;4:170051. doi: 10.1038/sdata.2017.51.

4.

Comparative Transcriptome Analysis Quantifies Immune Cell Transcript Levels, Metastatic Progression, and Survival in Osteosarcoma.

Scott MC, Temiz NA, Sarver AE, LaRue RS, Rathe SK, Varshney J, Wolf NK, Moriarity BS, O'Brien TD, Spector LG, Largaespada DA, Modiano JF, Subramanian S, Sarver AL.

Cancer Res. 2018 Jan 15;78(2):326-337. doi: 10.1158/0008-5472.CAN-17-0576. Epub 2017 Oct 24.

5.

Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen.

Ho YY, Starr TK, LaRue RS, Largaespada DA.

BMC Med Genomics. 2016 Apr 1;9:16. doi: 10.1186/s12920-016-0176-7.

6.

A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis.

Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, Modiano JF, Khanna C, Hewitt SM, Khokha R, Yang Y, Gorlick R, Dyer MA, Largaespada DA.

Nat Genet. 2015 Jun;47(6):615-24. doi: 10.1038/ng.3293. Epub 2015 May 11.

7.

NRASG12V oncogene facilitates self-renewal in a murine model of acute myelogenous leukemia.

Sachs Z, LaRue RS, Nguyen HT, Sachs K, Noble KE, Mohd Hassan NA, Diaz-Flores E, Rathe SK, Sarver AL, Bendall SC, Ha NA, Diers MD, Nolan GP, Shannon KM, Largaespada DA.

Blood. 2014 Nov 20;124(22):3274-83. doi: 10.1182/blood-2013-08-521708. Epub 2014 Oct 14.

8.

Antigen-specific culture of memory-like CD8 T cells for adoptive immunotherapy.

Litterman AJ, Zellmer DM, LaRue RS, Jameson SC, Largaespada DA.

Cancer Immunol Res. 2014 Sep;2(9):839-45. doi: 10.1158/2326-6066.CIR-14-0038. Epub 2014 May 22.

9.

Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors.

Hultquist JF, Binka M, LaRue RS, Simon V, Harris RS.

J Virol. 2012 Mar;86(5):2874-7. doi: 10.1128/JVI.06950-11. Epub 2011 Dec 28.

10.

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

Jäger S, Kim DY, Hultquist JF, Shindo K, LaRue RS, Kwon E, Li M, Anderson BD, Yen L, Stanley D, Mahon C, Kane J, Franks-Skiba K, Cimermancic P, Burlingame A, Sali A, Craik CS, Harris RS, Gross JD, Krogan NJ.

Nature. 2011 Dec 21;481(7381):371-5. doi: 10.1038/nature10693.

11.

Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1.

Hultquist JF, Lengyel JA, Refsland EW, LaRue RS, Lackey L, Brown WL, Harris RS.

J Virol. 2011 Nov;85(21):11220-34. doi: 10.1128/JVI.05238-11. Epub 2011 Aug 10.

12.

A single amino acid in human APOBEC3F alters susceptibility to HIV-1 Vif.

Albin JS, LaRue RS, Weaver JA, Brown WL, Shindo K, Harjes E, Matsuo H, Harris RS.

J Biol Chem. 2010 Dec 24;285(52):40785-92. doi: 10.1074/jbc.M110.173161. Epub 2010 Oct 22.

13.

Lentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity.

Larue RS, Lengyel J, Jónsson SR, Andrésdóttir V, Harris RS.

J Virol. 2010 Aug;84(16):8193-201. doi: 10.1128/JVI.00685-10. Epub 2010 Jun 2.

14.

The artiodactyl APOBEC3 innate immune repertoire shows evidence for a multi-functional domain organization that existed in the ancestor of placental mammals.

LaRue RS, Jónsson SR, Silverstein KA, Lajoie M, Bertrand D, El-Mabrouk N, Hötzel I, Andrésdóttir V, Smith TP, Harris RS.

BMC Mol Biol. 2008 Nov 18;9:104. doi: 10.1186/1471-2199-9-104.

15.

Guidelines for naming nonprimate APOBEC3 genes and proteins.

LaRue RS, Andrésdóttir V, Blanchard Y, Conticello SG, Derse D, Emerman M, Greene WC, Jónsson SR, Landau NR, Löchelt M, Malik HS, Malim MH, Münk C, O'Brien SJ, Pathak VK, Strebel K, Wain-Hobson S, Yu XF, Yuhki N, Harris RS.

J Virol. 2009 Jan;83(2):494-7. doi: 10.1128/JVI.01976-08. Epub 2008 Nov 5. No abstract available.

16.

The restriction of zoonotic PERV transmission by human APOBEC3G.

Jónsson SR, LaRue RS, Stenglein MD, Fahrenkrug SC, Andrésdóttir V, Harris RS.

PLoS One. 2007 Sep 12;2(9):e893.

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