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Items: 1 to 50 of 82

1.

A recombinant human IgG1 Fc multimer designed to mimic the active fraction of IVIG in autoimmunity.

Zhang X, Owens J, Olsen HS, So E, Burch E, McCroskey MC, Li X, Weber GL, Bennett D, Rybin D, Zhou H, Hao H, Mérigeon EY, Block DS, LaRosa G, Strome SE.

JCI Insight. 2019 Jan 24;4(2). pii: 121905. doi: 10.1172/jci.insight.121905. [Epub ahead of print]

2.

Transversal dose distribution optimization for laser-accelerated proton beam medical applications by means of Geant4.

Milluzzo G, Pipek J, Amico AG, Cirrone GAP, Cuttone G, Korn G, Larosa G, Leanza R, Margarone D, Petringa G, Russo A, Schillaci F, Scuderi V, Romano F.

Phys Med. 2018 Oct;54:166-172. doi: 10.1016/j.ejmp.2018.07.008. Epub 2018 Aug 1.

PMID:
30076107
3.

A fully recombinant human IgG1 Fc multimer (GL-2045) inhibits complement-mediated cytotoxicity and induces iC3b.

Zhou H, Olsen H, So E, Mérigeon E, Rybin D, Owens J, LaRosa G, Block DS, Strome SE, Zhang X.

Blood Adv. 2017 Mar 14;1(8):504-515. doi: 10.1182/bloodadvances.2016001917. eCollection 2017 Mar 14.

4.

Corrigendum: Clinical and Research Activities at the CATANA Facility of INFN-LNS: From the Conventional Hadrontherapy to the Laser-Driven Approach.

Cirrone GAP, Cuttone G, Raffaele L, Salamone V, Avitabile T, Privitera G, Spatola C, Amico AG, Larosa G, Leanza R, Margarone D, Milluzzo G, Patti V, Petringa G, Romano F, Russo A, Russo A, Sabini MG, Schillaci F, Scuderi V, Valastro LM.

Front Oncol. 2017 Oct 31;7:247. doi: 10.3389/fonc.2017.00247. eCollection 2017.

5.

Clinical and Research Activities at the CATANA Facility of INFN-LNS: From the Conventional Hadrontherapy to the Laser-Driven Approach.

Cirrone GAP, Cuttone G, Raffaele L, Salamone V, Avitabile T, Privitera G, Spatola C, Amico AG, Larosa G, Leanza R, Margarone D, Milluzzo G, Patti V, Petringa G, Romano F, Russo A, Russo A, Sabini MG, Scuderi V, Schillaci F, Valastro LM.

Front Oncol. 2017 Sep 19;7:223. doi: 10.3389/fonc.2017.00223. eCollection 2017. Erratum in: Front Oncol. 2017 Oct 31;7:247.

6.

In vitro and in vivo effects of 2,4 diaminoquinazoline inhibitors of the decapping scavenger enzyme DcpS: Context-specific modulation of SMN transcript levels.

Cherry JJ, DiDonato CJ, Androphy EJ, Calo A, Potter K, Custer SK, Du S, Foley TL, Gopalsamy A, Reedich EJ, Gordo SM, Gordon W, Hosea N, Jones LH, Krizay DK, LaRosa G, Li H, Mathur S, Menard CA, Patel P, Ramos-Zayas R, Rietz A, Rong H, Zhang B, Tones MA.

PLoS One. 2017 Sep 25;12(9):e0185079. doi: 10.1371/journal.pone.0185079. eCollection 2017.

7.

Long-Term Monitoring of Dolphin Biosonar Activity in Deep Pelagic Waters of the Mediterranean Sea.

Caruso F, Alonge G, Bellia G, De Domenico E, Grammauta R, Larosa G, Mazzola S, Riccobene G, Pavan G, Papale E, Pellegrino C, Pulvirenti S, Sciacca V, Simeone F, Speziale F, Viola S, Buscaino G.

Sci Rep. 2017 Jun 28;7(1):4321. doi: 10.1038/s41598-017-04608-6.

8.

Design of Potent mRNA Decapping Scavenger Enzyme (DcpS) Inhibitors with Improved Physicochemical Properties To Investigate the Mechanism of Therapeutic Benefit in Spinal Muscular Atrophy (SMA).

Gopalsamy A, Narayanan A, Liu S, Parikh MD, Kyne RE Jr, Fadeyi O, Tones MA, Cherry JJ, Nabhan JF, LaRosa G, Petersen DN, Menard C, Foley TL, Noell S, Ren Y, Loria PM, Maglich-Goodwin J, Rong H, Jones LH.

J Med Chem. 2017 Apr 13;60(7):3094-3108. doi: 10.1021/acs.jmedchem.7b00124. Epub 2017 Mar 16.

PMID:
28257199
9.

Size Distribution of Sperm Whales Acoustically Identified during Long Term Deep-Sea Monitoring in the Ionian Sea.

Caruso F, Sciacca V, Bellia G, De Domenico E, Larosa G, Papale E, Pellegrino C, Pulvirenti S, Riccobene G, Simeone F, Speziale F, Viola S, Pavan G.

PLoS One. 2015 Dec 16;10(12):e0144503. doi: 10.1371/journal.pone.0144503. eCollection 2015.

10.

Annual Acoustic Presence of Fin Whale (Balaenoptera physalus) Offshore Eastern Sicily, Central Mediterranean Sea.

Sciacca V, Caruso F, Beranzoli L, Chierici F, De Domenico E, Embriaco D, Favali P, Giovanetti G, Larosa G, Marinaro G, Papale E, Pavan G, Pellegrino C, Pulvirenti S, Simeone F, Viola S, Riccobene G.

PLoS One. 2015 Nov 18;10(11):e0141838. doi: 10.1371/journal.pone.0141838. eCollection 2015.

11.

Two novel α7 nicotinic acetylcholine receptor ligands: in vitro properties and their efficacy in collagen-induced arthritis in mice.

van Maanen MA, Papke RL, Koopman FA, Koepke J, Bevaart L, Clark R, Lamppu D, Elbaum D, LaRosa GJ, Tak PP, Vervoordeldonk MJ.

PLoS One. 2015 Jan 24;10(1):e0116227. doi: 10.1371/journal.pone.0116227. eCollection 2015.

12.

Discovery of novel 2-((pyridin-3-yloxy)methyl)piperazines as α7 nicotinic acetylcholine receptor modulators for the treatment of inflammatory disorders.

Clark RB, Lamppu D, Libertine L, McDonough A, Kumar A, LaRosa G, Rush R, Elbaum D.

J Med Chem. 2014 May 22;57(10):3966-83. doi: 10.1021/jm5004599. Epub 2014 May 9.

PMID:
24814197
13.

Deep-sea bioluminescence blooms after dense water formation at the ocean surface.

Tamburini C, Canals M, Durrieu de Madron X, Houpert L, Lefèvre D, Martini S, D'Ortenzio F, Robert A, Testor P, Aguilar JA, Samarai IA, Albert A, André M, Anghinolfi M, Anton G, Anvar S, Ardid M, Jesus AC, Astraatmadja TL, Aubert JJ, Baret B, Basa S, Bertin V, Biagi S, Bigi A, Bigongiari C, Bogazzi C, Bou-Cabo M, Bouhou B, Bouwhuis MC, Brunner J, Busto J, Camarena F, Capone A, Cârloganu C, Carminati G, Carr J, Cecchini S, Charif Z, Charvis P, Chiarusi T, Circella M, Coniglione R, Costantini H, Coyle P, Curtil C, Decowski P, Dekeyser I, Deschamps A, Donzaud C, Dornic D, Dorosti HQ, Drouhin D, Eberl T, Emanuele U, Ernenwein JP, Escoffier S, Fermani P, Ferri M, Flaminio V, Folger F, Fritsch U, Fuda JL, Galatà S, Gay P, Giacomelli G, Giordano V, Gómez-González JP, Graf K, Guillard G, Halladjian G, Hallewell G, van Haren H, Hartman J, Heijboer AJ, Hello Y, Hernández-Rey JJ, Herold B, Hößl J, Hsu CC, de Jong M, Kadler M, Kalekin O, Kappes A, Katz U, Kavatsyuk O, Kooijman P, Kopper C, Kouchner A, Kreykenbohm I, Kulikovskiy V, Lahmann R, Lamare P, Larosa G, Lattuada D, Lim G, Presti DL, Loehner H, Loucatos S, Mangano S, Marcelin M, Margiotta A, Martinez-Mora JA, Meli A, Montaruli T, Moscoso L, Motz H, Neff M, Nezri EN, Palioselitis D, Păvălaş GE, Payet K, Payre P, Petrovic J, Piattelli P, Picot-Clemente N, Popa V, Pradier T, Presani E, Racca C, Reed C, Riccobene G, Richardt C, Richter R, Rivière C, Roensch K, Rostovtsev A, Ruiz-Rivas J, Rujoiu M, Russo VG, Salesa F, Sánchez-Losa A, Sapienza P, Schöck F, Schuller JP, Schussler F, Shanidze R, Simeone F, Spies A, Spurio M, Steijger JJ, Stolarczyk T, Taiuti MG, Toscano S, Vallage B, Van Elewyck V, Vannoni G, Vecchi M, Vernin P, Wijnker G, Wilms J, de Wolf E, Yepes H, Zaborov D, De Dios Zornoza J, Zúñiga J.

PLoS One. 2013 Jul 10;8(7):e67523. doi: 10.1371/journal.pone.0067523. Print 2013.

14.

Acoustic transmitters for underwater neutrino telescopes.

Ardid M, Martínez-Mora JA, Bou-Cabo M, Larosa G, Adrián-Martínez S, Llorens CD.

Sensors (Basel). 2012;12(4):4113-32. doi: 10.3390/s120404113. Epub 2012 Mar 27.

15.

Role of the cholinergic nervous system in rheumatoid arthritis: aggravation of arthritis in nicotinic acetylcholine receptor α7 subunit gene knockout mice.

van Maanen MA, Stoof SP, Larosa GJ, Vervoordeldonk MJ, Tak PP.

Ann Rheum Dis. 2010 Sep;69(9):1717-23. doi: 10.1136/ard.2009.118554. Epub 2010 May 28.

PMID:
20511609
16.

Stimulation of nicotinic acetylcholine receptors attenuates collagen-induced arthritis in mice.

van Maanen MA, Lebre MC, van der Poll T, LaRosa GJ, Elbaum D, Vervoordeldonk MJ, Tak PP.

Arthritis Rheum. 2009 Jan;60(1):114-22. doi: 10.1002/art.24177.

17.

Human dispersal of Trichinella spiralis in domesticated pigs.

Rosenthal BM, LaRosa G, Zarlenga D, Dunams D, Chunyu Y, Mingyuan L, Pozio E.

Infect Genet Evol. 2008 Dec;8(6):799-805. doi: 10.1016/j.meegid.2008.07.008. Epub 2008 Jul 30.

PMID:
18718558
18.

The role of public health nurses in emergency preparedness and response: a position paper of the Association of State and Territorial Directors of Nursing.

Jakeway CC, LaRosa G, Cary A, Schoenfisch S; Association of State and Territorial Directors of Nursing.

Public Health Nurs. 2008 Jul-Aug;25(4):353-61. doi: 10.1111/j.1525-1446.2008.00716.x.

PMID:
18666941
19.

Selective cell adhesion inhibitors: Barbituric acid based alpha4beta7--MAdCAM inhibitors.

Harriman GC, Brewer M, Bennett R, Kuhn C, Bazin M, Larosa G, Skerker P, Cochran N, Gallant D, Baxter D, Picarella D, Jaffee B, Luly JR, Briskin MJ.

Bioorg Med Chem Lett. 2008 Apr 1;18(7):2509-12. doi: 10.1016/j.bmcl.2007.07.068. Epub 2007 Aug 21.

PMID:
18331794
20.

Activation of the cholinergic anti-inflammatory pathway ameliorates postoperative ileus in mice.

The FO, Boeckxstaens GE, Snoek SA, Cash JL, Bennink R, Larosa GJ, van den Wijngaard RM, Greaves DR, de Jonge WJ.

Gastroenterology. 2007 Oct;133(4):1219-28. Epub 2007 Jul 25.

PMID:
17919496
21.

Local stimulation of alpha7 cholinergic receptors inhibits LPS-induced TNF-alpha release in the mouse lung.

Giebelen IA, van Westerloo DJ, LaRosa GJ, de Vos AF, van der Poll T.

Shock. 2007 Dec;28(6):700-3.

PMID:
17621262
22.

Intrapulmonary delivery of ethyl pyruvate attenuates lipopolysaccharide- and lipoteichoic acid-induced lung inflammation in vivo.

van Zoelen MA, de Vos AF, Larosa GJ, Draing C, von Aulock S, van der Poll T.

Shock. 2007 Nov;28(5):570-5.

PMID:
17577142
23.
24.

Small molecule antagonists of the CC chemokine receptor 4 (CCR4).

Burdi DF, Chi S, Mattia K, Harrington C, Shi Z, Chen S, Jacutin-Porte S, Bennett R, Carson K, Yin W, Kansra V, Gonzalo JA, Coyle A, Jaffee B, Ocain T, Hodge M, LaRosa G, Harriman G.

Bioorg Med Chem Lett. 2007 Jun 1;17(11):3141-5. Epub 2007 Mar 15.

PMID:
17395464
25.

Selective alpha7-nicotinic acetylcholine receptor agonist GTS-21 improves survival in murine endotoxemia and severe sepsis.

Pavlov VA, Ochani M, Yang LH, Gallowitsch-Puerta M, Ochani K, Lin X, Levi J, Parrish WR, Rosas-Ballina M, Czura CJ, Larosa GJ, Miller EJ, Tracey KJ, Al-Abed Y.

Crit Care Med. 2007 Apr;35(4):1139-44.

PMID:
17334244
26.

HMGB1-secreting capacity of multiple cell lineages revealed by a novel HMGB1 ELISPOT assay.

Wähämaa H, Vallerskog T, Qin S, Lunderius C, LaRosa G, Andersson U, Harris HE.

J Leukoc Biol. 2007 Jan;81(1):129-36. Epub 2006 Sep 15.

PMID:
16980509
27.

Role of HMGB1 in apoptosis-mediated sepsis lethality.

Qin S, Wang H, Yuan R, Li H, Ochani M, Ochani K, Rosas-Ballina M, Czura CJ, Huston JM, Miller E, Lin X, Sherry B, Kumar A, Larosa G, Newman W, Tracey KJ, Yang H.

J Exp Med. 2006 Jul 10;203(7):1637-42. Epub 2006 Jul 3.

28.

The vagus nerve and nicotinic receptors modulate experimental pancreatitis severity in mice.

van Westerloo DJ, Giebelen IA, Florquin S, Bruno MJ, Larosa GJ, Ulloa L, Tracey KJ, van der Poll T.

Gastroenterology. 2006 May;130(6):1822-30.

PMID:
16697744
29.

Design, synthesis, and progress toward optimization of potent small molecule antagonists of CC chemokine receptor 8 (CCR8).

Ghosh S, Elder A, Guo J, Mani U, Patane M, Carson K, Ye Q, Bennett R, Chi S, Jenkins T, Guan B, Kolbeck R, Smith S, Zhang C, LaRosa G, Jaffee B, Yang H, Eddy P, Lu C, Uttamsingh V, Horlick R, Harriman G, Flynn D.

J Med Chem. 2006 May 4;49(9):2669-72.

PMID:
16640325
30.

Clinical experience with bevacizumab in colorectal cancer.

Salesi N, Bossone G, Veltri E, Di Cocco B, Marolla P, Pacetti U, Larosa G, Muni R, Vecchione A.

Anticancer Res. 2005 Sep-Oct;25(5):3619-23. Review.

31.

Myoepithelial carcinoma of parotid gland: a case report.

Lauro S, Trasatti L, Larosa G, Calabretta F, Di Gioia CR, Vecchione A.

Anticancer Res. 2003 May-Jun;23(3C):3041-4.

PMID:
12926158
32.

Selective lymphocyte chemokine receptor expression in the rheumatoid joint.

Ruth JH, Rottman JB, Katschke KJ Jr, Qin S, Wu L, LaRosa G, Ponath P, Pope RM, Koch AE.

Arthritis Rheum. 2001 Dec;44(12):2750-60.

33.

The CC chemokine eotaxin (CCL11) is a partial agonist of CC chemokine receptor 2b.

Martinelli R, Sabroe I, LaRosa G, Williams TJ, Pease JE.

J Biol Chem. 2001 Nov 16;276(46):42957-64. Epub 2001 Sep 14.

34.

Differential expression of chemokine receptors on peripheral blood, synovial fluid, and synovial tissue monocytes/macrophages in rheumatoid arthritis.

Katschke KJ Jr, Rottman JB, Ruth JH, Qin S, Wu L, LaRosa G, Ponath P, Park CC, Pope RM, Koch AE.

Arthritis Rheum. 2001 May;44(5):1022-32.

35.

Malignant bronchial Abrikossoff's tumor and small cell lung cancer: a case report and review.

Lauro S, Trasatti L, Bria E, Gelibter A, Larosa G, Vecchione A.

Anticancer Res. 2001 Jan-Feb;21(1B):563-5.

PMID:
11299804
36.

Basophil responses to chemokines are regulated by both sequential and cooperative receptor signaling.

Heinemann A, Hartnell A, Stubbs VE, Murakami K, Soler D, LaRosa G, Askenase PW, Williams TJ, Sabroe I.

J Immunol. 2000 Dec 15;165(12):7224-33.

37.

Functional differences between monocyte chemotactic protein-1 receptor A and monocyte chemotactic protein-1 receptor B expressed in a Jurkat T cell.

Sanders SK, Crean SM, Boxer PA, Kellner D, LaRosa GJ, Hunt SW 3rd.

J Immunol. 2000 Nov 1;165(9):4877-83.

38.

Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma.

Sica A, Saccani A, Bottazzi B, Bernasconi S, Allavena P, Gaetano B, Fei F, LaRosa G, Scotton C, Balkwill F, Mantovani A.

J Immunol. 2000 Jan 15;164(2):733-8.

39.

Human G protein-coupled receptor GPR-9-6/CC chemokine receptor 9 is selectively expressed on intestinal homing T lymphocytes, mucosal lymphocytes, and thymocytes and is required for thymus-expressed chemokine-mediated chemotaxis.

Zabel BA, Agace WW, Campbell JJ, Heath HM, Parent D, Roberts AI, Ebert EC, Kassam N, Qin S, Zovko M, LaRosa GJ, Yang LL, Soler D, Butcher EC, Ponath PD, Parker CM, Andrew DP.

J Exp Med. 1999 Nov 1;190(9):1241-56.

40.

Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones.

Penton-Rol G, Cota M, Polentarutti N, Luini W, Bernasconi S, Borsatti A, Sica A, LaRosa GJ, Sozzani S, Poli G, Mantovani A.

J Immunol. 1999 Sep 15;163(6):3524-9.

41.

[Elastic intramedullary nailing of the tibia with the Marchetti-Vicenzi nail. 43 treated cases].

Benmansour MB, Gottin M, Rouvillain JL, Larosa G, Dib C, Dintimille H, Catonné Y.

Rev Chir Orthop Reparatrice Appar Mot. 1999 Jun;85(3):267-76. French.

PMID:
10422132
42.

CCR2-64I polymorphism is not associated with altered CCR5 expression or coreceptor function.

Mariani R, Wong S, Mulder LC, Wilkinson DA, Reinhart AL, LaRosa G, Nibbs R, O'Brien TR, Michael NL, Connor RI, Macdonald M, Busch M, Koup RA, Landau NR.

J Virol. 1999 Mar;73(3):2450-9.

44.

The chemokine receptor CXCR3 mediates rapid and shear-resistant adhesion-induction of effector T lymphocytes by the chemokines IP10 and Mig.

Piali L, Weber C, LaRosa G, Mackay CR, Springer TA, Clark-Lewis I, Moser B.

Eur J Immunol. 1998 Mar;28(3):961-72.

45.

Interaction of chemokine receptor CCR5 with its ligands: multiple domains for HIV-1 gp120 binding and a single domain for chemokine binding.

Wu L, LaRosa G, Kassam N, Gordon CJ, Heath H, Ruffing N, Chen H, Humblias J, Samson M, Parmentier M, Moore JP, Mackay CR.

J Exp Med. 1997 Oct 20;186(8):1373-81.

46.

The second extracellular loop of CCR5 is the major determinant of ligand specificity.

Samson M, LaRosa G, Libert F, Paindavoine P, Detheux M, Vassart G, Parmentier M.

J Biol Chem. 1997 Oct 3;272(40):24934-41.

47.

High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines.

Uguccioni M, Mackay CR, Ochensberger B, Loetscher P, Rhis S, LaRosa GJ, Rao P, Ponath PD, Baggiolini M, Dahinden CA.

J Clin Invest. 1997 Sep 1;100(5):1137-43.

48.

Induction of monocyte chemoattractant protein-1 in the small veins of the ischemic and reperfused canine myocardium.

Kumar AG, Ballantyne CM, Michael LH, Kukielka GL, Youker KA, Lindsey ML, Hawkins HK, Birdsall HH, MacKay CR, LaRosa GJ, Rossen RD, Smith CW, Entman ML.

Circulation. 1997 Feb 4;95(3):693-700.

PMID:
9024159
49.

Complement C5a, TGF-beta 1, and MCP-1, in sequence, induce migration of monocytes into ischemic canine myocardium within the first one to five hours after reperfusion.

Birdsall HH, Green DM, Trial J, Youker KA, Burns AR, MacKay CR, LaRosa GJ, Hawkins HK, Smith CW, Michael LH, Entman ML, Rossen RD.

Circulation. 1997 Feb 4;95(3):684-92.

PMID:
9024158
50.

Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody.

Heath H, Qin S, Rao P, Wu L, LaRosa G, Kassam N, Ponath PD, Mackay CR.

J Clin Invest. 1997 Jan 15;99(2):178-84.

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