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Items: 7


Inflammasome inhibition blocks cardiac glycoside cell toxicity.

LaRock DL, Sands JS, Ettouati E, Richard M, Bushway PJ, Adler ED, Nizet V, LaRock CN.

J Biol Chem. 2019 Jul 12. pii: jbc.RA119.008330. doi: 10.1074/jbc.RA119.008330. [Epub ahead of print]


The Mla pathway is critical for Pseudomonas aeruginosa resistance to outer membrane permeabilization and host innate immune clearance.

Munguia J, LaRock DL, Tsunemoto H, Olson J, Cornax I, Pogliano J, Nizet V.

J Mol Med (Berl). 2017 Oct;95(10):1127-1136. doi: 10.1007/s00109-017-1579-4. Epub 2017 Aug 26.


IL-1β is an innate immune sensor of microbial proteolysis.

LaRock CN, Todd J, LaRock DL, Olson J, O'Donoghue AJ, Robertson AA, Cooper MA, Hoffman HM, Nizet V.

Sci Immunol. 2016 Aug;1(2). pii: eaah3539. doi: 10.1126/sciimmunol.aah3539. Epub 2016 Aug 19.


Salmonellae interactions with host processes.

LaRock DL, Chaudhary A, Miller SI.

Nat Rev Microbiol. 2015 Apr;13(4):191-205. doi: 10.1038/nrmicro3420. Epub 2015 Mar 9. Review.


Yersinia pestis insecticidal-like toxin complex (Tc) family proteins: characterization of expression, subcellular localization, and potential role in infection of the flea vector.

Spinner JL, Jarrett CO, LaRock DL, Miller SI, Collins CM, Hinnebusch BJ.

BMC Microbiol. 2012 Dec 18;12:296. doi: 10.1186/1471-2180-12-296.


A Salmonella typhimurium-translocated glycerophospholipid:cholesterol acyltransferase promotes virulence by binding to the RhoA protein switch regions.

LaRock DL, Brzovic PS, Levin I, Blanc MP, Miller SI.

J Biol Chem. 2012 Aug 24;287(35):29654-63. doi: 10.1074/jbc.M112.363598. Epub 2012 Jun 27.


Activation of a bacterial virulence protein by the GTPase RhoA.

Christen M, Coye LH, Hontz JS, LaRock DL, Pfuetzner RA, Megha, Miller SI.

Sci Signal. 2009 Nov 3;2(95):ra71. doi: 10.1126/scisignal.2000430.

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