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Items: 1 to 50 of 51

1.

Healthy Lifestyle-Based Approaches for Successful Vascular Aging.

Rossman MJ, LaRocca TJ, Martens CR, Seals DR.

J Appl Physiol (1985). 2018 Sep 13. doi: 10.1152/japplphysiol.00521.2018. [Epub ahead of print]

PMID:
30212305
2.

Hyperglycemia potentiates a shift from apoptosis to RIP1-dependent necroptosis.

McCaig WD, Patel PS, Sosunov SA, Shakerley NL, Smiraglia TA, Craft MM, Walker KM, Deragon MA, Ten VS, LaRocca TJ.

Cell Death Discov. 2018 May 10;4:55. doi: 10.1038/s41420-018-0058-1. eCollection 2018.

3.

A case of HTLV-1 associated adult T-cell lymphoma presenting with cutaneous lesions and tropical spastic paresis.

Sharma PV, Witteman M, Sundaravel S, Larocca T, Zhang Y, Goldsztajn H.

Intractable Rare Dis Res. 2018 Feb;7(1):61-64. doi: 10.5582/irdr.2017.01077.

4.

The Presence and Extension of Myocardial Fibrosis in the Undetermined Form of Chagas' Disease: A Study Using Magnetic Resonance.

Noya-Rabelo MM, Macedo CT, Larocca T, Machado A, Pacheco T, Torreão J, Souza BSF, Soares MBP, Ribeiro-Dos-Santos R, Correia LCL.

Arq Bras Cardiol. 2018 Feb;110(2):124-131. doi: 10.5935/abc.20180016. Epub 2018 Feb 19. English, Portuguese.

5.

Environmental pH modulates inerolysin activity via post-binding blockade.

Rampersaud R, Lewis EL, LaRocca TJ, Ratner AJ.

Sci Rep. 2018 Jan 24;8(1):1542. doi: 10.1038/s41598-018-19994-8.

6.

SDF-1 induces TNF-mediated apoptosis in cardiac myocytes.

Jarrah AA, Schwarskopf M, Wang ER, LaRocca T, Dhume A, Zhang S, Hadri L, Hajjar RJ, Schecter AD, Tarzami ST.

Apoptosis. 2018 Jan;23(1):79-91. doi: 10.1007/s10495-017-1438-3.

7.

Lack of association between serum syndecan-4, myocardial fibrosis and ventricular dysfunction in subjects with chronic Chagas disease.

Larocca TF, Macêdo CT, Noya-Rabelo M, Lemos Correia LC, Moreira MI, Caldas AC, Torreão JA, Souza BSF, Vasconcelos JF, Carvalho da Silva AS, Ribeiro Dos Santos R, Soares MBP.

PLoS One. 2017 Dec 12;12(12):e0189408. doi: 10.1371/journal.pone.0189408. eCollection 2017.

8.

Image-guided percutaneous intralesional administration of mesenchymal stromal cells in subjects with chronic complete spinal cord injury: a pilot study.

Larocca TF, Macêdo CT, Souza BSF, Andrade-Souza YM, Villarreal CF, Matos AC, Silva DN, da Silva KN, de Souza CLEM, Paixão DDS, Bezerra MDR, Alves RL, Soares MBP, Dos Santos RR.

Cytotherapy. 2017 Oct;19(10):1189-1196. doi: 10.1016/j.jcyt.2017.06.006. Epub 2017 Jul 29.

PMID:
28760352
9.

Trehalose supplementation reduces hepatic endoplasmic reticulum stress and inflammatory signaling in old mice.

Pagliassotti MJ, Estrada AL, Hudson WM, Wei Y, Wang D, Seals DR, Zigler ML, LaRocca TJ.

J Nutr Biochem. 2017 Jul;45:15-23. doi: 10.1016/j.jnutbio.2017.02.022. Epub 2017 Apr 6.

10.

Nutrition and other lifestyle influences on arterial aging.

LaRocca TJ, Martens CR, Seals DR.

Ageing Res Rev. 2017 Oct;39:106-119. doi: 10.1016/j.arr.2016.09.002. Epub 2016 Sep 28. Review.

PMID:
27693830
11.

Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways.

Lesniewski LA, Seals DR, Walker AE, Henson GD, Blimline MW, Trott DW, Bosshardt GC, LaRocca TJ, Lawson BR, Zigler MC, Donato AJ.

Aging Cell. 2017 Feb;16(1):17-26. doi: 10.1111/acel.12524. Epub 2016 Sep 22.

12.

Evaluation of Galectin-3 as a Novel Biomarker for Chagas Cardiomyopathy.

Noya-Rabelo MM, Larocca TF, Macêdo CT, Torreão JA, Souza BS, Vasconcelos JF, Souza LE, Silva AM, Ribeiro Dos Santos R, Correia LC, Soares MB.

Cardiology. 2017;136(1):33-39. Epub 2016 Aug 23.

PMID:
27548475
13.

Adding value to a graduate physiology seminar by focusing on public communication skills.

LaRocca TJ, Justice JN, Seals DR, Martens CR.

Adv Physiol Educ. 2016 Sep;40(3):365-9. doi: 10.1152/advan.00183.2015. No abstract available.

14.

Oral trehalose supplementation improves resistance artery endothelial function in healthy middle-aged and older adults.

Kaplon RE, Hill SD, Bispham NZ, Santos-Parker JR, Nowlan MJ, Snyder LL, Chonchol M, LaRocca TJ, McQueen MB, Seals DR.

Aging (Albany NY). 2016 Jun;8(6):1167-83. doi: 10.18632/aging.100962.

15.

Matricellular Protein CCN5 Reverses Established Cardiac Fibrosis.

Jeong D, Lee MA, Li Y, Yang DK, Kho C, Oh JG, Hong G, Lee A, Song MH, LaRocca TJ, Chen J, Liang L, Mitsuyama S, D'Escamard V, Kovacic JC, Kwak TH, Hajjar RJ, Park WJ.

J Am Coll Cardiol. 2016 Apr 5;67(13):1556-1568. doi: 10.1016/j.jacc.2016.01.030. Erratum in: J Am Coll Cardiol. 2016 Jun 14;67(23 ):2809.

16.

Hyperglycemic Conditions Prime Cells for RIP1-dependent Necroptosis.

LaRocca TJ, Sosunov SA, Shakerley NL, Ten VS, Ratner AJ.

J Biol Chem. 2016 Jun 24;291(26):13753-61. doi: 10.1074/jbc.M116.716027. Epub 2016 Apr 29.

17.

Optimization of oncological ¹⁸F-FDG PET/CT imaging based on a multiparameter analysis.

Menezes VO, Machado MA, Queiroz CC, Souza SO, d'Errico F, Namías M, Larocca TF, Soares MB.

Med Phys. 2016 Feb;43(2):930-8. doi: 10.1118/1.4940354.

PMID:
26843253
18.

Assessment of Galectin-3 Polymorphism in Subjects with Chronic Chagas Disease.

Cruz Gda S, Angelo AL, Larocca TF, Macedo CT, Noya-Rabelo M, Correia LC, Torreão JA, Souza BS, Santos RR, Soares MB.

Arq Bras Cardiol. 2015 Nov;105(5):472-8. doi: 10.5935/abc.20150105. Epub 2015 Aug 25. English, Portuguese.

19.

CD59 signaling and membrane pores drive Syk-dependent erythrocyte necroptosis.

LaRocca TJ, Stivison EA, Mal-Sarkar T, Hooven TA, Hod EA, Spitalnik SL, Ratner AJ.

Cell Death Dis. 2015 May 28;6:e1773. doi: 10.1038/cddis.2015.135.

20.

Assessment of speckle tracking strain predictive value for myocardial fibrosis in subjects with Chagas disease.

Macedo CT, Larocca TF, Noya-Rabelo M, Correia LCL, Moreira MIG, Caldas AC, Torreão JA, de Freitas Souza BS, Dos Santos RR, Soares MBP.

Int J Cardiol Heart Vasc. 2015 May 25;8:75-80. doi: 10.1016/j.ijcha.2015.05.007. eCollection 2015 Sep 1.

21.

Physiological geroscience: targeting function to increase healthspan and achieve optimal longevity.

Seals DR, Justice JN, LaRocca TJ.

J Physiol. 2016 Apr 15;594(8):2001-24. doi: 10.1113/jphysiol.2014.282665. Epub 2015 Mar 11. Review.

22.

Aerobic exercise and other healthy lifestyle factors that influence vascular aging.

Santos-Parker JR, LaRocca TJ, Seals DR.

Adv Physiol Educ. 2014 Dec;38(4):296-307. doi: 10.1152/advan.00088.2014. Review.

23.

Safety and neurological assessments after autologous transplantation of bone marrow mesenchymal stem cells in subjects with chronic spinal cord injury.

Mendonça MV, Larocca TF, de Freitas Souza BS, Villarreal CF, Silva LF, Matos AC, Novaes MA, Bahia CM, de Oliveira Melo Martinez AC, Kaneto CM, Furtado SB, Sampaio GP, Soares MB, dos Santos RR.

Stem Cell Res Ther. 2014 Nov 17;5(6):126. doi: 10.1186/scrt516.

24.

Human-specific bacterial pore-forming toxins induce programmed necrosis in erythrocytes.

LaRocca TJ, Stivison EA, Hod EA, Spitalnik SL, Cowan PJ, Randis TM, Ratner AJ.

MBio. 2014 Aug 26;5(5):e01251-14. doi: 10.1128/mBio.01251-14.

25.

Mitochondrial quality control and age-associated arterial stiffening.

LaRocca TJ, Hearon CM Jr, Henson GD, Seals DR.

Exp Gerontol. 2014 Oct;58:78-82. doi: 10.1016/j.exger.2014.07.008. Epub 2014 Jul 14.

26.

You're only as old as your arteries: translational strategies for preserving vascular endothelial function with aging.

Seals DR, Kaplon RE, Gioscia-Ryan RA, LaRocca TJ.

Physiology (Bethesda). 2014 Jul;29(4):250-64. doi: 10.1152/physiol.00059.2013. Review.

27.

Mitochondria-targeted antioxidant (MitoQ) ameliorates age-related arterial endothelial dysfunction in mice.

Gioscia-Ryan RA, LaRocca TJ, Sindler AL, Zigler MC, Murphy MP, Seals DR.

J Physiol. 2014 Jun 15;592(12):2549-61. doi: 10.1113/jphysiol.2013.268680. Epub 2014 Mar 24.

28.

Selective association of outer surface lipoproteins with the lipid rafts of Borrelia burgdorferi.

Toledo A, Crowley JT, Coleman JL, LaRocca TJ, Chiantia S, London E, Benach JL.

MBio. 2014 Mar 11;5(2):e00899-14. doi: 10.1128/mBio.00899-14.

29.

Vaginolysin drives epithelial ultrastructural responses to Gardnerella vaginalis.

Randis TM, Zaklama J, LaRocca TJ, Los FC, Lewis EL, Desai P, Rampersaud R, Amaral FE, Ratner AJ.

Infect Immun. 2013 Dec;81(12):4544-50. doi: 10.1128/IAI.00627-13. Epub 2013 Sep 30.

30.

Proving lipid rafts exist: membrane domains in the prokaryote Borrelia burgdorferi have the same properties as eukaryotic lipid rafts.

LaRocca TJ, Pathak P, Chiantia S, Toledo A, Silvius JR, Benach JL, London E.

PLoS Pathog. 2013;9(5):e1003353. doi: 10.1371/journal.ppat.1003353. Epub 2013 May 16.

31.

The autophagy enhancer spermidine reverses arterial aging.

LaRocca TJ, Gioscia-Ryan RA, Hearon CM Jr, Seals DR.

Mech Ageing Dev. 2013 Jul-Aug;134(7-8):314-20. doi: 10.1016/j.mad.2013.04.004. Epub 2013 Apr 20.

32.

Transplantation of adipose tissue mesenchymal stem cells in experimental chronic chagasic cardiopathy.

Larocca TF, Souza BS, Silva CA, Kaneto CM, Alcantara AC, Azevedo CM, Castro MF, Macambira SG, Soares MB, Ribeiro-dos-Santos R.

Arq Bras Cardiol. 2013 May;100(5):460-8. doi: 10.5935/abc.20130058. Epub 2013 Apr 9. English, Portuguese.

33.

Lipid exchange between Borrelia burgdorferi and host cells.

Crowley JT, Toledo AM, LaRocca TJ, Coleman JL, London E, Benach JL.

PLoS Pathog. 2013 Jan;9(1):e1003109. doi: 10.1371/journal.ppat.1003109. Epub 2013 Jan 10.

34.

CXCR4 gene transfer prevents pressure overload induced heart failure.

Larocca TJ, Jeong D, Kohlbrenner E, Lee A, Chen J, Hajjar RJ, Tarzami ST.

J Mol Cell Cardiol. 2012 Aug;53(2):223-32. doi: 10.1016/j.yjmcc.2012.05.016. Epub 2012 Jun 3.

35.

Na+/Ca2+ exchanger-1 protects against systolic failure in the Akitains2 model of diabetic cardiomyopathy via a CXCR4/NF-κB pathway.

LaRocca TJ, Fabris F, Chen J, Benhayon D, Zhang S, McCollum L, Schecter AD, Cheung JY, Sobie EA, Hajjar RJ, Lebeche D.

Am J Physiol Heart Circ Physiol. 2012 Aug 1;303(3):H353-67. doi: 10.1152/ajpheart.01198.2011. Epub 2012 May 18.

36.

Translational evidence that impaired autophagy contributes to arterial ageing.

LaRocca TJ, Henson GD, Thorburn A, Sindler AL, Pierce GL, Seals DR.

J Physiol. 2012 Jul 15;590(14):3305-16. doi: 10.1113/jphysiol.2012.229690. Epub 2012 May 8.

37.

MicroRNA changes in human arterial endothelial cells with senescence: relation to apoptosis, eNOS and inflammation.

Rippe C, Blimline M, Magerko KA, Lawson BR, LaRocca TJ, Donato AJ, Seals DR.

Exp Gerontol. 2012 Jan;47(1):45-51. doi: 10.1016/j.exger.2011.10.004. Epub 2011 Oct 15.

38.

Habitually exercising older men do not demonstrate age-associated vascular endothelial oxidative stress.

Pierce GL, Donato AJ, LaRocca TJ, Eskurza I, Silver AE, Seals DR.

Aging Cell. 2011 Dec;10(6):1032-7. doi: 10.1111/j.1474-9726.2011.00748.x. Epub 2011 Oct 17.

39.

A new model of congestive heart failure in rats.

Chen J, Chemaly ER, Liang LF, LaRocca TJ, Yaniz-Galende E, Hajjar RJ.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H994-1003. doi: 10.1152/ajpheart.00245.2011. Epub 2011 Jun 17.

40.

Cholesterol lipids of Borrelia burgdorferi form lipid rafts and are required for the bactericidal activity of a complement-independent antibody.

LaRocca TJ, Crowley JT, Cusack BJ, Pathak P, Benach J, London E, Garcia-Monco JC, Benach JL.

Cell Host Microbe. 2010 Oct 21;8(4):331-42. doi: 10.1016/j.chom.2010.09.001.

41.

β2-Adrenergic receptor signaling in the cardiac myocyte is modulated by interactions with CXCR4.

LaRocca TJ, Schwarzkopf M, Altman P, Zhang S, Gupta A, Gomes I, Alvin Z, Champion HC, Haddad G, Hajjar RJ, Devi LA, Schecter AD, Tarzami ST.

J Cardiovasc Pharmacol. 2010 Nov;56(5):548-59. doi: 10.1097/FJC.0b013e3181f713fe.

42.

Short-term calorie restriction reverses vascular endothelial dysfunction in old mice by increasing nitric oxide and reducing oxidative stress.

Rippe C, Lesniewski L, Connell M, LaRocca T, Donato A, Seals D.

Aging Cell. 2010 Jun;9(3):304-12. doi: 10.1111/j.1474-9726.2010.00557.x. Epub 2010 Mar 13.

43.

Leukocyte telomere length is preserved with aging in endurance exercise-trained adults and related to maximal aerobic capacity.

LaRocca TJ, Seals DR, Pierce GL.

Mech Ageing Dev. 2010 Feb;131(2):165-7. doi: 10.1016/j.mad.2009.12.009. Epub 2010 Jan 12.

44.

The bactericidal effect of a complement-independent antibody is osmolytic and specific to Borrelia.

LaRocca TJ, Holthausen DJ, Hsieh C, Renken C, Mannella CA, Benach JL.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10752-7. doi: 10.1073/pnas.0901858106. Epub 2009 Jun 19.

45.
46.

Reduced vascular tetrahydrobiopterin (BH4) and endothelial function with ageing: is it time for a chronic BH4 supplementation trial in middle-aged and older adults?

Pierce GL, Larocca TJ.

J Physiol. 2008 Jun 1;586(11):2673-4. doi: 10.1113/jphysiol.2008.154229. Epub 2008 Apr 3. No abstract available.

47.

The important and diverse roles of antibodies in the host response to Borrelia infections.

LaRocca TJ, Benach JL.

Curr Top Microbiol Immunol. 2008;319:63-103. Review.

PMID:
18080415
48.

Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis.

André P, LaRocca T, Delaney SM, Lin PH, Vincent D, Sinha U, Conley PB, Phillips DR.

Circulation. 2003 Nov 25;108(21):2697-703. Epub 2003 Nov 3.

PMID:
14597584
49.

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries.

Andre P, Delaney SM, LaRocca T, Vincent D, DeGuzman F, Jurek M, Koller B, Phillips DR, Conley PB.

J Clin Invest. 2003 Aug;112(3):398-406.

50.

A Nonsurgical Method for the Placement of Transpyloric (Nasoenteric) Feeding Tubes Using Fluoroscopic Guidance in Dogs.

Wohl JS, Hudson JA, Larocca TJ.

Contemp Top Lab Anim Sci. 1999 Mar;38(2):65-68.

PMID:
12086437

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