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Characterization of Hydrothermal Deposition of Copper Oxide Nanoleaves on Never-Dried Bacterial Cellulose.

Warren WR, LaJeunesse DR.

Polymers (Basel). 2019 Oct 27;11(11). pii: E1762. doi: 10.3390/polym11111762.


Nanosphere Lithography of Chitin and Chitosan with Colloidal and Self-Masking Patterning.

Chandran R, Nowlin K, LaJeunesse DR.

Polymers (Basel). 2018 Feb;10(2). pii: 218. doi: 10.3390/polym10020218. Epub 2018 Feb 23.


Characterization of Pseudomonas aeruginosa Films on Different Inorganic Surfaces before and after UV Light Exposure.

Gulyuk AV, LaJeunesse DR, Collazo R, Ivanisevic A.

Langmuir. 2018 Sep 11;34(36):10806-10815. doi: 10.1021/acs.langmuir.8b02079. Epub 2018 Aug 30.


Noninvasive Stimulation of Neurotypic Cells Using Persistent Photoconductivity of Gallium Nitride.

Snyder PJ, Reddy P, Kirste R, LaJeunesse DR, Collazo R, Ivanisevic A.

ACS Omega. 2018 Jan 31;3(1):615-621. doi: 10.1021/acsomega.7b01894. Epub 2018 Jan 19.


Bioelectronics communication: encoding yeast regulatory responses using nanostructured gallium nitride thin films.

Snyder PJ, LaJeunesse DR, Reddy P, Kirste R, Collazo R, Ivanisevic A.

Nanoscale. 2018 Jun 21;10(24):11506-11516. doi: 10.1039/c8nr03684e.


Alteration of Wnt5a expression and of the non-canonical Wnt/PCP and Wnt/PKC-Ca2+ pathways in human osteoarthritis osteoblasts.

Martineau X, Abed É, Martel-Pelletier J, Pelletier JP, Lajeunesse D.

PLoS One. 2017 Aug 4;12(8):e0180711. doi: 10.1371/journal.pone.0180711. eCollection 2017.


Beneficial effect of resveratrol on phenotypic features and activity of osteoarthritic osteoblasts.

Abed É, Delalandre A, Lajeunesse D.

Arthritis Res Ther. 2017 Jun 30;19(1):151. doi: 10.1186/s13075-017-1365-2.


Platelet rich plasma (PRP) induces chondroprotection via increasing autophagy, anti-inflammatory markers, and decreasing apoptosis in human osteoarthritic cartilage.

Moussa M, Lajeunesse D, Hilal G, El Atat O, Haykal G, Serhal R, Chalhoub A, Khalil C, Alaaeddine N.

Exp Cell Res. 2017 Mar 1;352(1):146-156. doi: 10.1016/j.yexcr.2017.02.012. Epub 2017 Feb 13.


SEM characterization of anatomical variation in chitin organization in insect and arthropod cuticles.

Chandran R, Williams L, Hung A, Nowlin K, LaJeunesse D.

Micron. 2016 Mar;82:74-85. doi: 10.1016/j.micron.2015.12.010. Epub 2015 Dec 29.


The HIV Workforce in New York State: Does Patient Volume Correlate with Quality?

O'Neill M, Karelas GD, Feller DJ, Knudsen-Strong E, Lajeunesse D, Tsui D, Gordon P, Agins BD.

Clin Infect Dis. 2015 Dec 15;61(12):1871-7. doi: 10.1093/cid/civ719. Epub 2015 Sep 30.


Targeting the Atypical Chemokine Receptor ACKR3/CXCR7: Phase 1 - Phage Display Peptide Identification and Characterization.

Vestal RD, LaJeunesse DR, Taylor EW.

Curr Top Med Chem. 2016;16(13):1427-40. Review.


Elevated hepatocyte growth factor levels in osteoarthritis osteoblasts contribute to their altered response to bone morphogenetic protein-2 and reduced mineralization capacity.

Abed E, Bouvard B, Martineau X, Jouzeau JY, Reboul P, Lajeunesse D.

Bone. 2015 Jun;75:111-9. doi: 10.1016/j.bone.2015.02.001. Epub 2015 Feb 7.


PPARγ deficiency results in severe, accelerated osteoarthritis associated with aberrant mTOR signalling in the articular cartilage.

Vasheghani F, Zhang Y, Li YH, Blati M, Fahmi H, Lussier B, Roughley P, Lagares D, Endisha H, Saffar B, Lajeunesse D, Marshall WK, Rampersaud YR, Mahomed NN, Gandhi R, Pelletier JP, Martel-Pelletier J, Kapoor M.

Ann Rheum Dis. 2015 Mar;74(3):569-78. doi: 10.1136/annrheumdis-2014-205743. Epub 2015 Jan 8.


Adhesion-dependent rupturing of Saccharomyces cerevisiae on biological antimicrobial nanostructured surfaces.

Nowlin K, Boseman A, Covell A, LaJeunesse D.

J R Soc Interface. 2015 Jan 6;12(102):20140999.


Identification of two populations of osteoarthritic osteoblasts according to the 1,25[OH]₂ vitamin D₃ potency to stimulate osteocalcin.

Hu Y, Liu Y, Lajeunesse D, Mainard D, Jouzeau JY, Reboul P.

Biomed Mater Eng. 2015;25(1 Suppl):103-10. doi: 10.3233/BME-141230.


Hypoxia and vitamin D differently contribute to leptin and dickkopf-related protein 2 production in human osteoarthritic subchondral bone osteoblasts.

Bouvard B, Abed E, Yéléhé-Okouma M, Bianchi A, Mainard D, Netter P, Jouzeau JY, Lajeunesse D, Reboul P.

Arthritis Res Ther. 2014 Oct 14;16(5):459. doi: 10.1186/s13075-014-0459-3.


Low sirtuin 1 levels in human osteoarthritis subchondral osteoblasts lead to abnormal sclerostin expression which decreases Wnt/β-catenin activity.

Abed É, Couchourel D, Delalandre A, Duval N, Pelletier JP, Martel-Pelletier J, Lajeunesse D.

Bone. 2014 Feb;59:28-36. doi: 10.1016/j.bone.2013.10.020. Epub 2013 Oct 31.


Ultrastructural analysis of wild type and mutant Drosophila melanogaster using helium ion microscopy.

Boseman A, Nowlin K, Ashraf S, Yang J, Lajeunesse D.

Micron. 2013 Aug;51:26-35. doi: 10.1016/j.micron.2013.06.005. Epub 2013 Jun 24.


Strontium ranelate reduces the progression of experimental dog osteoarthritis by inhibiting the expression of key proteases in cartilage and of IL-1β in the synovium.

Pelletier JP, Kapoor M, Fahmi H, Lajeunesse D, Blesius A, Maillet J, Martel-Pelletier J.

Ann Rheum Dis. 2013 Feb;72(2):250-7. doi: 10.1136/annrheumdis-2012-201710. Epub 2012 Oct 13.


A study of Epstein-Barr virus BRLF1 activity in a Drosophila model system.

Adamson A, LaJeunesse D.

ScientificWorldJournal. 2012;2012:347597. doi: 10.1100/2012/347597. Epub 2012 Apr 26.


R-spondins are newly recognized players in osteoarthritis that regulate Wnt signaling in osteoblasts.

Abed É, Chan TF, Delalandre A, Martel-Pelletier J, Pelletier JP, Lajeunesse D.

Arthritis Rheum. 2011 Dec;63(12):3865-75. doi: 10.1002/art.30625.


A Drosophila model for genetic analysis of influenza viral/host interactions.

Adamson AL, Chohan K, Swenson J, LaJeunesse D.

Genetics. 2011 Oct;189(2):495-506. doi: 10.1534/genetics.111.132290. Epub 2011 Jul 20.


Tiludronate treatment improves structural changes and symptoms of osteoarthritis in the canine anterior cruciate ligament model.

Moreau M, Rialland P, Pelletier JP, Martel-Pelletier J, Lajeunesse D, Boileau C, Caron J, Frank D, Lussier B, del Castillo JR, Beauchamp G, Gauvin D, Bertaim T, Thibaud D, Troncy E.

Arthritis Res Ther. 2011 Jun 21;13(3):R98. doi: 10.1186/ar3373.


Elevated Dickkopf-2 levels contribute to the abnormal phenotype of human osteoarthritic osteoblasts.

Chan TF, Couchourel D, Abed E, Delalandre A, Duval N, Lajeunesse D.

J Bone Miner Res. 2011 Jul;26(7):1399-410. doi: 10.1002/jbmr.358.


Role of proinflammatory cytokines in the pathophysiology of osteoarthritis.

Kapoor M, Martel-Pelletier J, Lajeunesse D, Pelletier JP, Fahmi H.

Nat Rev Rheumatol. 2011 Jan;7(1):33-42. doi: 10.1038/nrrheum.2010.196. Epub 2010 Nov 30. Review.


Peristalsis in the junction region of the Drosophila larval midgut is modulated by DH31 expressing enteroendocrine cells.

LaJeunesse DR, Johnson B, Presnell JS, Catignas KK, Zapotoczny G.

BMC Physiol. 2010 Aug 10;10:14. doi: 10.1186/1472-6793-10-14.


Local leptin production in osteoarthritis subchondral osteoblasts may be responsible for their abnormal phenotypic expression.

Mutabaruka MS, Aoulad Aissa M, Delalandre A, Lavigne M, Lajeunesse D.

Arthritis Res Ther. 2010;12(1):R20. doi: 10.1186/ar2925. Epub 2010 Feb 8.


Targeting subchondral bone for treating osteoarthritis: what is the evidence?

Kwan Tat S, Lajeunesse D, Pelletier JP, Martel-Pelletier J.

Best Pract Res Clin Rheumatol. 2010 Feb;24(1):51-70. doi: 10.1016/j.berh.2009.08.004. Review.


Modulation of OPG, RANK and RANKL by human chondrocytes and their implication during osteoarthritis.

Kwan Tat S, Amiable N, Pelletier JP, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J.

Rheumatology (Oxford). 2009 Dec;48(12):1482-90. doi: 10.1093/rheumatology/kep300. Epub 2009 Sep 17.


Altered mineralization of human osteoarthritic osteoblasts is attributable to abnormal type I collagen production.

Couchourel D, Aubry I, Delalandre A, Lavigne M, Martel-Pelletier J, Pelletier JP, Lajeunesse D.

Arthritis Rheum. 2009 May;60(5):1438-50. doi: 10.1002/art.24489.


Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.

Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C.

Bone. 2009 Jun;44(6):1143-50. doi: 10.1016/j.bone.2009.02.015. Epub 2009 Mar 2.


Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.

Kwan Tat S, Pelletier JP, Amiable N, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J.

Arthritis Rheum. 2008 Dec;58(12):3820-30. doi: 10.1002/art.24029.


An active role for soluble and membrane intercellular adhesion molecule-1 in osteoclast activity in vitro.

Fernandes JC, Shi Q, Benderdour M, Lajeunesse D, Lavigne P.

J Bone Miner Metab. 2008;26(6):543-50. doi: 10.1007/s00774-008-0866-0. Epub 2008 Nov 1.


Differential modulation of RANKL isoforms by human osteoarthritic subchondral bone osteoblasts: influence of osteotropic factors.

Tat SK, Pelletier JP, Lajeunesse D, Fahmi H, Duval N, Martel-Pelletier J.

Bone. 2008 Aug;43(2):284-91. doi: 10.1016/j.bone.2008.04.006. Epub 2008 Apr 26.


Chondroitin and glucosamine sulfate in combination decrease the pro-resorptive properties of human osteoarthritis subchondral bone osteoblasts: a basic science study.

Tat SK, Pelletier JP, Vergés J, Lajeunesse D, Montell E, Fahmi H, Lavigne M, Martel-Pelletier J.

Arthritis Res Ther. 2007;9(6):R117.


Abnormal insulin-like growth factor 1 signaling in human osteoarthritic subchondral bone osteoblasts.

Massicotte F, Aubry I, Martel-Pelletier J, Pelletier JP, Fernandes J, Lajeunesse D.

Arthritis Res Ther. 2006;8(6):R177.


New thoughts on the pathophysiology of osteoarthritis: one more step toward new therapeutic targets.

Martel-Pelletier J, Lajeunesse D, Fahmi H, Tardif G, Pelletier JP.

Curr Rheumatol Rep. 2006 Feb;8(1):30-6. Review.


Modulation of insulin-like growth factor 1 levels in human osteoarthritic subchondral bone osteoblasts.

Massicotte F, Fernandes JC, Martel-Pelletier J, Pelletier JP, Lajeunesse D.

Bone. 2006 Mar;38(3):333-41. Epub 2005 Oct 27.


The protective effect of licofelone on experimental osteoarthritis is correlated with the downregulation of gene expression and protein synthesis of several major cartilage catabolic factors: MMP-13, cathepsin K and aggrecanases.

Pelletier JP, Boileau C, Boily M, Brunet J, Mineau F, Geng C, Reboul P, Laufer S, Lajeunesse D, Martel-Pelletier J.

Arthritis Res Ther. 2005;7(5):R1091-102. Epub 2005 Jul 19.


Modeling early Epstein-Barr virus infection in Drosophila melanogaster: the BZLF1 protein.

Adamson AL, Wright N, LaJeunesse DR.

Genetics. 2005 Nov;171(3):1125-35. Epub 2005 Aug 3.


Epstein-Barr virus immediate-early proteins BZLF1 and BRLF1 alter mitochondrial morphology during lytic replication.

LaJeunesse DR, Brooks K, Adamson AL.

Biochem Biophys Res Commun. 2005 Jul 29;333(2):438-42.


Involvement of ICAM-1 in bone metabolism: a potential target in the treatment of bone diseases?

Lavigne P, Benderdour M, Shi Q, Lajeunesse D, Fernandes JC.

Expert Opin Biol Ther. 2005 Mar;5(3):313-20. Review.


Subchondral and trabecular bone metabolism regulation in canine experimental knee osteoarthritis.

Lavigne P, Benderdour M, Lajeunesse D, Reboul P, Shi Q, Pelletier JP, Martel-Pelletier J, Fernandes JC.

Osteoarthritis Cartilage. 2005 Apr;13(4):310-7.


Osteoarthritis: a metabolic disease induced by local abnormal leptin activity?

Lajeunesse D, Pelletier JP, Martel-Pelletier J.

Curr Rheumatol Rep. 2005 Apr;7(2):79-81. Review. No abstract available.


Altered subchondral osteoblast cellular metabolism in osteoarthritis: cytokines, eicosanoids, and growth factors.

Lajeunesse D.

J Musculoskelet Neuronal Interact. 2002 Dec;2(6):504-6. No abstract available.


Expression of ICAM-1 by osteoblasts in healthy individuals and in patients suffering from osteoarthritis and osteoporosis.

Lavigne P, Benderdour M, Lajeunesse D, Shi Q, Fernandes JC.

Bone. 2004 Aug;35(2):463-70.


Three new Drosophila markers of intracellular membranes.

LaJeunesse DR, Buckner SM, Lake J, Na C, Pirt A, Fromson K.

Biotechniques. 2004 May;36(5):784-8, 790.


The inhibition of subchondral bone resorption in the early phase of experimental dog osteoarthritis by licofelone is associated with a reduction in the synthesis of MMP-13 and cathepsin K.

Pelletier JP, Boileau C, Brunet J, Boily M, Lajeunesse D, Reboul P, Laufer S, Martel-Pelletier J.

Bone. 2004 Mar;34(3):527-38.


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