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Items: 28

1.

An Excitatory and Epileptogenic Effect of Dentate Gyrus Mossy Cells in a Mouse Model of Epilepsy.

Botterill JJ, Lu YL, LaFrancois JJ, Bernstein HL, Alcantara-Gonzalez D, Jain S, Leary P, Scharfman HE.

Cell Rep. 2019 Nov 26;29(9):2875-2889.e6. doi: 10.1016/j.celrep.2019.10.100.

2.

Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor.

Saadipour K, Tiberi A, Lombardo S, Grajales E, Montroull L, Mañucat-Tan NB, LaFrancois J, Cammer M, Mathews PM, Scharfman HE, Liao FF, Friedman WJ, Zhou XF, Tesco G, Chao MV.

Mol Cell Neurosci. 2019 Sep;99:103395. doi: 10.1016/j.mcn.2019.103395. Epub 2019 Aug 15.

PMID:
31422108
3.

Adult neurogenesis in the mouse dentate gyrus protects the hippocampus from neuronal injury following severe seizures.

Jain S, LaFrancois JJ, Botterill JJ, Alcantara-Gonzalez D, Scharfman HE.

Hippocampus. 2019 Aug;29(8):683-709. doi: 10.1002/hipo.23062. Epub 2019 Jan 23.

PMID:
30672046
4.

Epigenetic suppression of hippocampal calbindin-D28k by ΔFosB drives seizure-related cognitive deficits.

You JC, Muralidharan K, Park JW, Petrof I, Pyfer MS, Corbett BF, LaFrancois JJ, Zheng Y, Zhang X, Mohila CA, Yoshor D, Rissman RA, Nestler EJ, Scharfman HE, Chin J.

Nat Med. 2017 Nov;23(11):1377-1383. doi: 10.1038/nm.4413. Epub 2017 Oct 16.

5.

Hilar granule cells of the mouse dentate gyrus: effects of age, septotemporal location, strain, and selective deletion of the proapoptotic gene BAX.

Bermudez-Hernandez K, Lu YL, Moretto J, Jain S, LaFrancois JJ, Duffy AM, Scharfman HE.

Brain Struct Funct. 2017 Sep;222(7):3147-3161. doi: 10.1007/s00429-017-1391-5. Epub 2017 Mar 17.

6.

Interictal spikes during sleep are an early defect in the Tg2576 mouse model of β-amyloid neuropathology.

Kam K, Duffy ÁM, Moretto J, LaFrancois JJ, Scharfman HE.

Sci Rep. 2016 Jan 28;6:20119. doi: 10.1038/srep20119.

7.

Interictal spike frequency varies with ovarian cycle stage in a rat model of epilepsy.

D'Amour J, Magagna-Poveda A, Moretto J, Friedman D, LaFrancois JJ, Pearce P, Fenton AA, MacLusky NJ, Scharfman HE.

Exp Neurol. 2015 Jul;269:102-19. doi: 10.1016/j.expneurol.2015.04.003. Epub 2015 Apr 10.

8.

Suppression of adult neurogenesis increases the acute effects of kainic acid.

Iyengar SS, LaFrancois JJ, Friedman D, Drew LJ, Denny CA, Burghardt NS, Wu MV, Hsieh J, Hen R, Scharfman HE.

Exp Neurol. 2015 Feb;264:135-49. doi: 10.1016/j.expneurol.2014.11.009. Epub 2014 Dec 2.

9.

p75NTR, but not proNGF, is upregulated following status epilepticus in mice.

VonDran MW, LaFrancois J, Padow VA, Friedman WJ, Scharfman HE, Milner TA, Hempstead BL.

ASN Neuro. 2014 Sep 25;6(5). pii: 1759091414552185. doi: 10.1177/1759091414552185. Print 2014.

10.

Histological correlation of diffusional kurtosis and white matter modeling metrics in cuprizone-induced corpus callosum demyelination.

Falangola MF, Guilfoyle DN, Tabesh A, Hui ES, Nie X, Jensen JH, Gerum SV, Hu C, LaFrancois J, Collins HR, Helpern JA.

NMR Biomed. 2014 Aug;27(8):948-57. doi: 10.1002/nbm.3140. Epub 2014 Jun 3.

11.

proBDNF negatively regulates neuronal remodeling, synaptic transmission, and synaptic plasticity in hippocampus.

Yang J, Harte-Hargrove LC, Siao CJ, Marinic T, Clarke R, Ma Q, Jing D, Lafrancois JJ, Bath KG, Mark W, Ballon D, Lee FS, Scharfman HE, Hempstead BL.

Cell Rep. 2014 May 8;7(3):796-806. doi: 10.1016/j.celrep.2014.03.040. Epub 2014 Apr 17.

12.

Spike-wave discharges in adult Sprague-Dawley rats and their implications for animal models of temporal lobe epilepsy.

Pearce PS, Friedman D, Lafrancois JJ, Iyengar SS, Fenton AA, Maclusky NJ, Scharfman HE.

Epilepsy Behav. 2014 Mar;32:121-31. doi: 10.1016/j.yebeh.2014.01.004. Epub 2014 Feb 15. Review.

13.

Increased dopaminergic neuron sensitivity to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in transgenic mice expressing mutant A53T alpha-synuclein.

Yu WH, Matsuoka Y, Sziráki I, Hashim A, Lafrancois J, Sershen H, Duff KE.

Neurochem Res. 2008 May;33(5):902-11. Epub 2007 Nov 13.

PMID:
17999181
14.

Collapsin response mediator protein-2 hyperphosphorylation is an early event in Alzheimer's disease progression.

Cole AR, Noble W, van Aalten L, Plattner F, Meimaridou R, Hogan D, Taylor M, LaFrancois J, Gunn-Moore F, Verkhratsky A, Oddo S, LaFerla F, Giese KP, Dineley KT, Duff K, Richardson JC, Yan SD, Hanger DP, Allan SM, Sutherland C.

J Neurochem. 2007 Nov;103(3):1132-44. Epub 2007 Aug 7.

15.

Antibody against C-terminal Abeta selectively elevates plasma Abeta.

Gray AJ, Sakaguchi G, Shiratori C, Becker AG, LaFrancois J, Aisen PS, Duff K, Matsuoka Y.

Neuroreport. 2007 Feb 12;18(3):293-6.

PMID:
17314674
16.

An Abeta sequestration approach using non-antibody Abeta binding agents.

Matsuoka Y, Shao L, Debnath M, Lafrancois J, Becker A, Gray A, Aisen P, Mathis C, Klunk W, Duff K.

Curr Alzheimer Res. 2005 Apr;2(2):265-8.

PMID:
15974928
17.

Inhibition of glycogen synthase kinase-3 by lithium correlates with reduced tauopathy and degeneration in vivo.

Noble W, Planel E, Zehr C, Olm V, Meyerson J, Suleman F, Gaynor K, Wang L, LaFrancois J, Feinstein B, Burns M, Krishnamurthy P, Wen Y, Bhat R, Lewis J, Dickson D, Duff K.

Proc Natl Acad Sci U S A. 2005 May 10;102(19):6990-5. Epub 2005 May 2.

18.

Evidence for peripheral clearance of cerebral Abeta protein following chronic, active Abeta immunization in PSAPP mice.

Lemere CA, Spooner ET, LaFrancois J, Malester B, Mori C, Leverone JF, Matsuoka Y, Taylor JW, DeMattos RB, Holtzman DM, Clements JD, Selkoe DJ, Duff KE.

Neurobiol Dis. 2003 Oct;14(1):10-8.

PMID:
13678662
19.

Presenilin redistribution associated with aberrant cholesterol transport enhances beta-amyloid production in vivo.

Burns M, Gaynor K, Olm V, Mercken M, LaFrancois J, Wang L, Mathews PM, Noble W, Matsuoka Y, Duff K.

J Neurosci. 2003 Jul 2;23(13):5645-9.

20.

Cdk5 is a key factor in tau aggregation and tangle formation in vivo.

Noble W, Olm V, Takata K, Casey E, Mary O, Meyerson J, Gaynor K, LaFrancois J, Wang L, Kondo T, Davies P, Burns M, Veeranna, Nixon R, Dickson D, Matsuoka Y, Ahlijanian M, Lau LF, Duff K.

Neuron. 2003 May 22;38(4):555-65.

21.

Co-localization of cholesterol, apolipoprotein E and fibrillar Abeta in amyloid plaques.

Burns MP, Noble WJ, Olm V, Gaynor K, Casey E, LaFrancois J, Wang L, Duff K.

Brain Res Mol Brain Res. 2003 Jan 31;110(1):119-25.

PMID:
12573540
22.

Novel therapeutic approach for the treatment of Alzheimer's disease by peripheral administration of agents with an affinity to beta-amyloid.

Matsuoka Y, Saito M, LaFrancois J, Saito M, Gaynor K, Olm V, Wang L, Casey E, Lu Y, Shiratori C, Lemere C, Duff K.

J Neurosci. 2003 Jan 1;23(1):29-33.

23.

Modulation of A(beta) peptides by estrogen in mouse models.

Zheng H, Xu H, Uljon SN, Gross R, Hardy K, Gaynor J, Lafrancois J, Simpkins J, Refolo LM, Petanceska S, Wang R, Duff K.

J Neurochem. 2002 Jan;80(1):191-6.

24.

A cholesterol-lowering drug reduces beta-amyloid pathology in a transgenic mouse model of Alzheimer's disease.

Refolo LM, Pappolla MA, LaFrancois J, Malester B, Schmidt SD, Thomas-Bryant T, Tint GS, Wang R, Mercken M, Petanceska SS, Duff KE.

Neurobiol Dis. 2001 Oct;8(5):890-9.

PMID:
11592856
25.

Lack of nigral pathology in transgenic mice expressing human alpha-synuclein driven by the tyrosine hydroxylase promoter.

Matsuoka Y, Vila M, Lincoln S, McCormack A, Picciano M, LaFrancois J, Yu X, Dickson D, Langston WJ, McGowan E, Farrer M, Hardy J, Duff K, Przedborski S, Di Monte DA.

Neurobiol Dis. 2001 Jun;8(3):535-9.

PMID:
11442360
26.

Inflammatory responses to amyloidosis in a transgenic mouse model of Alzheimer's disease.

Matsuoka Y, Picciano M, Malester B, LaFrancois J, Zehr C, Daeschner JM, Olschowka JA, Fonseca MI, O'Banion MK, Tenner AJ, Lemere CA, Duff K.

Am J Pathol. 2001 Apr;158(4):1345-54.

27.

Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model.

Refolo LM, Malester B, LaFrancois J, Bryant-Thomas T, Wang R, Tint GS, Sambamurti K, Duff K, Pappolla MA.

Neurobiol Dis. 2000 Aug;7(4):321-31. Erratum in: Neurobiol Dis 2000 Dec;7(6 Pt B):690.

PMID:
10964604
28.

Self-administration of ethanol: towards the location of predisposing polygenes in quasi-congenic animal models.

Vadász C, Fleischer A, LaFrancois J, Mao RF.

Alcohol. 1996 Nov-Dec;13(6):617-20.

PMID:
8949958

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