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Items: 8

1.

Structure Overhaul Affords a Potent Purine PI3Kδ Inhibitor with Improved Tolerability.

Methot JL, Zhou H, Kattar SD, McGowan MA, Wilson K, Garcia Y, Deng Y, Altman M, Fradera X, Lesburg C, Fischmann T, Li C, Alves S, Shah S, Fernandez R, Goldenblatt P, Hill A, Shaffer L, Chen D, Tong V, McLeod RL, Yu H, Bass A, Kemper R, Gatto NT, LaFranco-Scheuch L, Trotter BW, Guzi T, Katz JD.

J Med Chem. 2019 May 9;62(9):4370-4382. doi: 10.1021/acs.jmedchem.8b01818. Epub 2019 Apr 22.

PMID:
30986068
2.

Use of a Bile Salt Export Pump Knockdown Rat Susceptibility Model to Interrogate Mechanism of Drug-Induced Liver Toxicity.

Li Y, Evers R, Hafey MJ, Cheon K, Duong H, Lynch D, LaFranco-Scheuch L, Pacchione S, Tamburino AM, Tanis KQ, Geddes K, Holder D, Zhang NR, Kang W, Gonzalez RJ, Galijatovic-Idrizbegovic A, Pearson KM, Lebron JA, Glaab WE, Sistare FD.

Toxicol Sci. 2019 Jul 1;170(1):180-198. doi: 10.1093/toxsci/kfz079.

PMID:
30903168
3.

A Performance Evaluation of Liver and Skeletal Muscle-Specific miRNAs in Rat Plasma to Detect Drug-Induced Injury.

Bailey WJ, Barnum JE, Erdos Z, LaFranco-Scheuch L, Lane P, Vlasakova K, Sistare FD, Glaab WE.

Toxicol Sci. 2019 Mar 1;168(1):110-125. doi: 10.1093/toxsci/kfy282.

PMID:
30496518
4.

Vascular Imaging of Matrix Metalloproteinase Activity as an Informative Preclinical Biomarker of Drug-induced Vascular Injury.

Gonzalez RJ, Lin SA, Bednar B, Connolly B, LaFranco-Scheuch L, Mesfin GM, Philip T, Patel S, Johnson T, Sistare FD, Glaab WE.

Toxicol Pathol. 2017 Jul;45(5):633-648. doi: 10.1177/0192623317720731.

PMID:
28830331
5.

Systemic pan-AMPK activator MK-8722 improves glucose homeostasis but induces cardiac hypertrophy.

Myers RW, Guan HP, Ehrhart J, Petrov A, Prahalada S, Tozzo E, Yang X, Kurtz MM, Trujillo M, Gonzalez Trotter D, Feng D, Xu S, Eiermann G, Holahan MA, Rubins D, Conarello S, Niu X, Souza SC, Miller C, Liu J, Lu K, Feng W, Li Y, Painter RE, Milligan JA, He H, Liu F, Ogawa A, Wisniewski D, Rohm RJ, Wang L, Bunzel M, Qian Y, Zhu W, Wang H, Bennet B, LaFranco Scheuch L, Fernandez GE, Li C, Klimas M, Zhou G, van Heek M, Biftu T, Weber A, Kelley DE, Thornberry N, Erion MD, Kemp DM, Sebhat IK.

Science. 2017 Aug 4;357(6350):507-511. doi: 10.1126/science.aah5582. Epub 2017 Jul 13.

PMID:
28705990
6.

Sneezing, nasal discharge, dyspnea and sudden death in rabbits.

Geertsema RS, LaFranco-Scheuch L, Jenné KJ, Richter PJ.

Lab Anim (NY). 2008 Jan;37(1):17. No abstract available.

PMID:
18094696
8.

Pulmonary coccidioidomycosis in a neonatal foal.

Maleski K, Magdesian KG, LaFranco-Scheuch L, Pappagianis D, Carlson GP.

Vet Rec. 2002 Oct 26;151(17):505-8.

PMID:
12430999

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