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Items: 11


PEA-15 unphosphorylated at both serine 104 and serine 116 inhibits ovarian cancer cell tumorigenicity and progression through blocking β-catenin.

Lee J, Bartholomeusz C, Krishnamurthy S, Liu P, Saso H, Lafortune TA, Hortobagyi GN, Ueno NT.

Oncogenesis. 2012 Jul 16;1:e22. doi: 10.1038/oncsis.2012.22.


Antitumor activity of NVP-BKM120--a selective pan class I PI3 kinase inhibitor showed differential forms of cell death based on p53 status of glioma cells.

Koul D, Fu J, Shen R, LaFortune TA, Wang S, Tiao N, Kim YW, Liu JL, Ramnarian D, Yuan Y, Garcia-Echevrria C, Maira SM, Yung WK.

Clin Cancer Res. 2012 Jan 1;18(1):184-95. doi: 10.1158/1078-0432.CCR-11-1558. Epub 2011 Nov 7.


Establishment and characterization of clinically relevant models of ependymoma: a true challenge for targeted therapy.

Guan S, Shen R, Lafortune T, Tiao N, Houghton P, Yung WK, Koul D.

Neuro Oncol. 2011 Jul;13(7):748-58. doi: 10.1093/neuonc/nor037. Epub 2011 Jun 8.


Silencing kinase-interacting stathmin gene enhances erlotinib sensitivity by inhibiting Ser¹⁰ p27 phosphorylation in epidermal growth factor receptor-expressing breast cancer.

Zhang D, Tari AM, Akar U, Arun BK, LaFortune TA, Nieves-Alicea R, Hortobagyi GN, Ueno NT.

Mol Cancer Ther. 2010 Nov;9(11):3090-9. doi: 10.1158/1535-7163.MCT-10-0362. Epub 2010 Nov 2.


Epidermal growth factor receptor tyrosine kinase inhibitor reverses mesenchymal to epithelial phenotype and inhibits metastasis in inflammatory breast cancer.

Zhang D, LaFortune TA, Krishnamurthy S, Esteva FJ, Cristofanilli M, Liu P, Lucci A, Singh B, Hung MC, Hortobagyi GN, Ueno NT.

Clin Cancer Res. 2009 Nov 1;15(21):6639-48. doi: 10.1158/1078-0432.CCR-09-0951. Epub 2009 Oct 13.


NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas.

Liu TJ, Koul D, LaFortune T, Tiao N, Shen RJ, Maira SM, Garcia-Echevrria C, Yung WK.

Mol Cancer Ther. 2009 Aug;8(8):2204-10. doi: 10.1158/1535-7163.MCT-09-0160. Epub 2009 Aug 11.


Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma.

Milano V, Piao Y, LaFortune T, de Groot J.

Mol Cancer Ther. 2009 Feb;8(2):394-406. doi: 10.1158/1535-7163.MCT-08-0669. Epub 2009 Feb 3.


Cell cycle-dependent nuclear export of phosphatase and tensin homologue tumor suppressor is regulated by the phosphoinositide-3-kinase signaling cascade.

Liu JL, Mao Z, LaFortune TA, Alonso MM, Gallick GE, Fueyo J, Yung WK.

Cancer Res. 2007 Nov 15;67(22):11054-63.


Inhibition of both focal adhesion kinase and insulin-like growth factor-I receptor kinase suppresses glioma proliferation in vitro and in vivo.

Liu TJ, LaFortune T, Honda T, Ohmori O, Hatakeyama S, Meyer T, Jackson D, de Groot J, Yung WK.

Mol Cancer Ther. 2007 Apr;6(4):1357-67.


Inhibition of Akt survival pathway by a small-molecule inhibitor in human glioblastoma.

Koul D, Shen R, Bergh S, Sheng X, Shishodia S, Lafortune TA, Lu Y, de Groot JF, Mills GB, Yung WK.

Mol Cancer Ther. 2006 Mar;5(3):637-44.


Effect of food preferences on nutrient intake.


J Am Diet Assoc. 1957 Feb;33(2):98-103. No abstract available.


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