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Items: 10


Ureadepsipeptides as ClpP Activators.

Griffith EC, Zhao Y, Singh AP, Conlon BP, Tangallapally R, Shadrick WR, Liu J, Wallace MJ, Yang L, Elmore JM, Li Y, Zheng Z, Miller DJ, Cheramie MN, Lee RB, LaFleur MD, Lewis K, Lee RE.

ACS Infect Dis. 2019 Nov 8;5(11):1915-1925. doi: 10.1021/acsinfecdis.9b00245. Epub 2019 Oct 24.


In Vivo and In Vitro Effects of a ClpP-Activating Antibiotic against Vancomycin-Resistant Enterococci.

Brown Gandt A, Griffith EC, Lister IM, Billings LL, Han A, Tangallapally R, Zhao Y, Singh AP, Lee RE, LaFleur MD.

Antimicrob Agents Chemother. 2018 Jul 27;62(8). pii: e00424-18. doi: 10.1128/AAC.00424-18. Print 2018 Aug.


In vitro and in vivo activities of HPi1, a selective antimicrobial against Helicobacter pylori.

Gavrish E, Shrestha B, Chen C, Lister I, North EJ, Yang L, Lee RE, Han A, Williams B, Charnuska D, Coleman K, Lewis K, LaFleur MD.

Antimicrob Agents Chemother. 2014 Jun;58(6):3255-60. doi: 10.1128/AAC.02573-13. Epub 2014 Mar 31.


Activated ClpP kills persisters and eradicates a chronic biofilm infection.

Conlon BP, Nakayasu ES, Fleck LE, LaFleur MD, Isabella VM, Coleman K, Leonard SN, Smith RD, Adkins JN, Lewis K.

Nature. 2013 Nov 21;503(7476):365-70. doi: 10.1038/nature12790. Epub 2013 Nov 13.


Potentiation of azole antifungals by 2-adamantanamine.

Lafleur MD, Sun L, Lister I, Keating J, Nantel A, Long L, Ghannoum M, North J, Lee RE, Coleman K, Dahl T, Lewis K.

Antimicrob Agents Chemother. 2013 Aug;57(8):3585-92. doi: 10.1128/AAC.00294-13. Epub 2013 May 20.


Novel high-throughput screen against Candida albicans identifies antifungal potentiators and agents effective against biofilms.

LaFleur MD, Lucumi E, Napper AD, Diamond SL, Lewis K.

J Antimicrob Chemother. 2011 Apr;66(4):820-6. doi: 10.1093/jac/dkq530. Epub 2011 Jan 28.


Patients with long-term oral carriage harbor high-persister mutants of Candida albicans.

Lafleur MD, Qi Q, Lewis K.

Antimicrob Agents Chemother. 2010 Jan;54(1):39-44. doi: 10.1128/AAC.00860-09. Epub 2009 Oct 19.


[Roles of drug efflux pump genes in the mechanism of Saccharomyces albicans biofilm drug tolerance].

Qi QG, Lafleur MD.

Hua Xi Kou Qiang Yi Xue Za Zhi. 2009 Apr;27(2):191-4. Chinese.


Candida albicans biofilms produce antifungal-tolerant persister cells.

LaFleur MD, Kumamoto CA, Lewis K.

Antimicrob Agents Chemother. 2006 Nov;50(11):3839-46. Epub 2006 Aug 21.

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