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Items: 1 to 50 of 65

1.

To the editor in reply to Dr. Crow's letter.

Mustelin T, Ukadike K, LaCava J, Taylor MS.

Arthritis Rheumatol. 2019 Sep 12. doi: 10.1002/art.41104. [Epub ahead of print]

PMID:
31513363
2.

High prevalence and disease correlation of autoantibodies against p40 encoded by long interspersed nuclear elements (LINE-1) in systemic lupus erythematosus.

Carter V, LaCava J, Taylor MS, Liang SY, Mustelin C, Ukadike KC, Bengtsson A, Lood C, Mustelin T.

Arthritis Rheumatol. 2019 Jul 24. doi: 10.1002/art.41054. [Epub ahead of print]

PMID:
31342656
3.

Identification of RNase-sensitive LINE-1 Ribonucleoprotein Interactions by Differential Affinity Immobilization.

Jiang H, Taylor MS, Molloy KR, Altukhov I, LaCava J.

Bio Protoc. 2019 Apr 5;9(7). pii: e3200. doi: 10.21769/BioProtoc.3200.

4.

RNA Binding Proteins as Regulators of Retrotransposon-Induced Exonization.

LaCava J.

Bioessays. 2019 Feb;41(2):e1800263. doi: 10.1002/bies.201800263. Epub 2019 Feb 8. No abstract available.

PMID:
30734956
5.

Targeting the CALR interactome in myeloproliferative neoplasms.

Pronier E, Cifani P, Merlinsky TR, Berman KB, Somasundara AVH, Rampal RK, LaCava J, Wei KE, Pastore F, Maag JL, Park J, Koche R, Kentsis A, Levine RL.

JCI Insight. 2018 Nov 15;3(22). pii: 122703. doi: 10.1172/jci.insight.122703.

6.

Polycomb complexes associate with enhancers and promote oncogenic transcriptional programs in cancer through multiple mechanisms.

Chan HL, Beckedorff F, Zhang Y, Garcia-Huidobro J, Jiang H, Colaprico A, Bilbao D, Figueroa ME, LaCava J, Shiekhattar R, Morey L.

Nat Commun. 2018 Aug 23;9(1):3377. doi: 10.1038/s41467-018-05728-x.

7.

Functions of unconventional mammalian translational GTPases GTPBP1 and GTPBP2.

Zinoviev A, Goyal A, Jindal S, LaCava J, Komar AA, Rodnina MV, Hellen CUT, Pestova TV.

Genes Dev. 2018 Sep 1;32(17-18):1226-1241. doi: 10.1101/gad.314724.118. Epub 2018 Aug 14.

8.

LINE-1 protein localization and functional dynamics during the cell cycle.

Mita P, Wudzinska A, Sun X, Andrade J, Nayak S, Kahler DJ, Badri S, LaCava J, Ueberheide B, Yun CY, Fenyö D, Boeke JD.

Elife. 2018 Jan 8;7. pii: e30058. doi: 10.7554/eLife.30058.

9.

Dissection of affinity captured LINE-1 macromolecular complexes.

Taylor MS, Altukhov I, Molloy KR, Mita P, Jiang H, Adney EM, Wudzinska A, Badri S, Ischenko D, Eng G, Burns KH, Fenyö D, Chait BT, Alexeev D, Rout MP, Boeke JD, LaCava J.

Elife. 2018 Jan 8;7. pii: e30094. doi: 10.7554/eLife.30094.

10.

High frequency of aac(6')-Ib-cr gene associated with double mutations in gyrA and parC in Escherichia coli isolates from patients with urinary tract infections.

Volcão LM, Lacava JP, Gewehr MF, Leal VL, Ramis IB, Ramos DF, Gonçalves CV, Possuelo LG, Minarini LAR, da Silva PEA, von Groll A.

J Glob Antimicrob Resist. 2018 Jun;13:180-183. doi: 10.1016/j.jgar.2017.12.013. Epub 2018 Jan 4.

PMID:
29307860
11.

Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.

Winczura K, Schmid M, Iasillo C, Molloy KR, Harder LM, Andersen JS, LaCava J, Jensen TH.

Cell Rep. 2018 Jan 2;22(1):44-58. doi: 10.1016/j.celrep.2017.12.037.

12.

Tumor suppressor NPRL2 induces ROS production and DNA damage response.

Ma Y, Silveri L, LaCava J, Dokudovskaya S.

Sci Rep. 2017 Nov 10;7(1):15311. doi: 10.1038/s41598-017-15497-0.

13.

The Polycomb group protein CBX6 is an essential regulator of embryonic stem cell identity.

Santanach A, Blanco E, Jiang H, Molloy KR, Sansó M, LaCava J, Morey L, Di Croce L.

Nat Commun. 2017 Nov 1;8(1):1235. doi: 10.1038/s41467-017-01464-w.

14.

Affinity Purification of the RNA Degradation Complex, the Exosome, from HEK-293 Cells.

Domanski M, LaCava J.

Bio Protoc. 2017 Apr 20;7(8). pii: e2238. doi: 10.21769/BioProtoc.2238.

15.

RNA Degradation Assay Using RNA Exosome Complexes, Affinity-purified from HEK-293 Cells.

Domanski M, LaCava J.

Bio Protoc. 2017 Apr 20;7(8). pii: e2239. doi: 10.21769/BioProtoc.2239.

16.

Protein Complex Affinity Capture from Cryomilled Mammalian Cells.

LaCava J, Jiang H, Rout MP.

J Vis Exp. 2016 Dec 9;(118). doi: 10.3791/54518.

17.

Purification and analysis of endogenous human RNA exosome complexes.

Domanski M, Upla P, Rice WJ, Molloy KR, Ketaren NE, Stokes DL, Jensen TH, Rout MP, LaCava J.

RNA. 2016 Sep;22(9):1467-75. doi: 10.1261/rna.057760.116. Epub 2016 Jul 11.

18.

Protein Complex Purification by Affinity Capture.

LaCava J, Fernandez-Martinez J, Hakhverdyan Z, Rout MP.

Cold Spring Harb Protoc. 2016 Jul 1;2016(7). doi: 10.1101/pdb.top077545.

PMID:
27371601
19.

Density Gradient Ultracentrifugation to Isolate Endogenous Protein Complexes after Affinity Capture.

Fernandez-Martinez J, LaCava J, Rout MP.

Cold Spring Harb Protoc. 2016 Jul 1;2016(7). doi: 10.1101/pdb.prot087957.

PMID:
27371598
20.

Native Elution of Yeast Protein Complexes Obtained by Affinity Capture.

LaCava J, Fernandez-Martinez J, Rout MP.

Cold Spring Harb Protoc. 2016 Jul 1;2016(7). doi: 10.1101/pdb.prot087940.

PMID:
27371597
21.

Optimized Affinity Capture of Yeast Protein Complexes.

LaCava J, Fernandez-Martinez J, Hakhverdyan Z, Rout MP.

Cold Spring Harb Protoc. 2016 Jul 1;2016(7). doi: 10.1101/pdb.prot087932.

PMID:
27371596
22.

Characterization of L1-Ribonucleoprotein Particles.

Taylor MS, LaCava J, Dai L, Mita P, Burns KH, Rout MP, Boeke JD.

Methods Mol Biol. 2016;1400:311-38. doi: 10.1007/978-1-4939-3372-3_20.

23.

Design of Nanohybrid Systems from a Partially Fluorinated Organogelator and Syndiotactic Polystyrene Thermoreversible Gel.

Khan AN, Schmutz M, Lacava J, Al Ouahabi A, Nguyen TT, Mesini PJ, Guenet JM.

Langmuir. 2015 Jul 14;31(27):7666-72. doi: 10.1021/acs.langmuir.5b01339. Epub 2015 Jul 1.

PMID:
26094978
24.

Rapid, optimized interactomic screening.

Hakhverdyan Z, Domanski M, Hough LE, Oroskar AA, Oroskar AR, Keegan S, Dilworth DJ, Molloy KR, Sherman V, Aitchison JD, Fenyö D, Chait BT, Jensen TH, Rout MP, LaCava J.

Nat Methods. 2015 Jun;12(6):553-60. doi: 10.1038/nmeth.3395. Epub 2015 May 4.

25.

Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives.

LaCava J, Molloy KR, Taylor MS, Domanski M, Chait BT, Rout MP.

Biotechniques. 2015 Mar 1;58(3):103-19. doi: 10.2144/000114262. eCollection 2015 Mar.

26.

Expression and detection of LINE-1 ORF-encoded proteins.

Dai L, LaCava J, Taylor MS, Boeke JD.

Mob Genet Elements. 2014 May 22;4:e29319. eCollection 2014.

27.

On the behaviour of nanoparticles in oil-in-water emulsions with different surfactants.

Lacava J, Ouali AA, Raillard B, Kraus T.

Soft Matter. 2014 Mar 21;10(11):1696-704. doi: 10.1039/c3sm52949e.

PMID:
24652036
28.

The human cap-binding complex is functionally connected to the nuclear RNA exosome.

Andersen PR, Domanski M, Kristiansen MS, Storvall H, Ntini E, Verheggen C, Schein A, Bunkenborg J, Poser I, Hallais M, Sandberg R, Hyman A, LaCava J, Rout MP, Andersen JS, Bertrand E, Jensen TH.

Nat Struct Mol Biol. 2013 Dec;20(12):1367-76. doi: 10.1038/nsmb.2703. Epub 2013 Nov 24.

29.

Affinity proteomics reveals human host factors implicated in discrete stages of LINE-1 retrotransposition.

Taylor MS, LaCava J, Mita P, Molloy KR, Huang CR, Li D, Adney EM, Jiang H, Burns KH, Chait BT, Rout MP, Boeke JD, Dai L.

Cell. 2013 Nov 21;155(5):1034-48. doi: 10.1016/j.cell.2013.10.021.

30.

Improved native isolation of endogenous Protein A-tagged protein complexes.

LaCava J, Chandramouli N, Jiang H, Rout MP.

Biotechniques. 2013 Apr;54(4):213-6. doi: 10.2144/000114012.

31.

Improved methodology for the affinity isolation of human protein complexes expressed at near endogenous levels.

Domanski M, Molloy K, Jiang H, Chait BT, Rout MP, Jensen TH, LaCava J.

Biotechniques. 2012 May;0(0):1-6. doi: 10.2144/000113864.

32.

Nanoparticle clusters with Lennard-Jones geometries.

Lacava J, Born P, Kraus T.

Nano Lett. 2012 Jun 13;12(6):3279-82. doi: 10.1021/nl3013659. Epub 2012 May 14.

PMID:
22575027
33.

Doxorubicin plus sorafenib vs doxorubicin alone in patients with advanced hepatocellular carcinoma: a randomized trial.

Abou-Alfa GK, Johnson P, Knox JJ, Capanu M, Davidenko I, Lacava J, Leung T, Gansukh B, Saltz LB.

JAMA. 2010 Nov 17;304(19):2154-60. doi: 10.1001/jama.2010.1672.

PMID:
21081728
34.

RNA-quality control by the exosome.

Houseley J, LaCava J, Tollervey D.

Nat Rev Mol Cell Biol. 2006 Jul;7(7):529-39. Review.

PMID:
16829983
35.

RNA degradation by the exosome is promoted by a nuclear polyadenylation complex.

LaCava J, Houseley J, Saveanu C, Petfalski E, Thompson E, Jacquier A, Tollervey D.

Cell. 2005 Jun 3;121(5):713-24.

36.

Double modulation of 5-fluorouracil by trimetrexate and leucovorin in patients with advanced colorectal carcinoma.

Machiavelli MR, Salum G, Pérez JE, Ortiz EH, Romero AO, Bologna F, Vallejo CT, Lacava JA, Dominguez ME, Leone BA.

Am J Clin Oncol. 2004 Apr;27(2):149-54.

PMID:
15057154
37.

Docetaxel as neoadjuvant chemotherapy in patients with advanced cervical carcinoma.

Vallejo CT, Machiavelli MR, Pérez JE, Romero AO, Bologna F, Vicente H, Lacava JA, Ortiz EH, Cubero A, Focaccia G, Suttora G, Scenna M, Boughen JM, Leone BA.

Am J Clin Oncol. 2003 Oct;26(5):477-82.

PMID:
14528074
38.

Vinorelbine and paclitaxel for locoregional advanced or metastatic non-small-cell lung cancer.

Pérez JE, Machiavelli MR, Romero AO, Romero Acuña LA, Domínguez ME, Fasce H, Flores Acosta L, Marrone N, Romero Acuña JM, Langhi MJ, Amato S, Bologna F, Ortiz EH, Leone BA, Lacava JA, Vallejo CT.

Am J Clin Oncol. 2002 Aug;25(4):383-7.

PMID:
12151970
39.

mdm2-p53 Interaction: lack of correlation with the response to 5-fluorouracil in advanced colorectal cancer.

Paradiso A, Ranieri G, Simone G, Silvestris N, Costa A, De Lena M, Leone A, Vallejo C, Lacava J.

Oncology. 2002;62(3):278-85.

PMID:
12065876
40.

Expression of apoptosis-related markers and clinical outcome in patients with advanced colorectal cancer.

Paradiso A, Simone G, Lena MD, Leone B, Vallejo C, Lacava J, Dellapasqua S, Daidone MG, Costa A.

Br J Cancer. 2001 Mar 2;84(5):651-8.

41.

Neoadjuvant chemotherapy with ifosfamide, cisplatin, and vinorelbine in advanced squamous cell carcinoma of the cervix.

Vallejo CT, Pérez JE, Domínguez ME, Leone BA, Machiavelli MR, Lacava JA, Romero AO, Ortiz EH, Grasso S, Amato S, Rodríguez R, Barbieri M, Romero Acuña J, Focaccia G, Suttora G, Scenna M, Boughen JM, Romero Acuña LA, Langhi MJ.

Am J Clin Oncol. 2000 Oct;23(5):481-6.

PMID:
11039508
42.

Thymidilate synthase and p53 primary tumour expression as predictive factors for advanced colorectal cancer patients.

Paradiso A, Simone G, Petroni S, Leone B, Vallejo C, Lacava J, Romero A, Machiavelli M, De Lena M, Allegra CJ, Johnston PG.

Br J Cancer. 2000 Feb;82(3):560-7.

43.

Metastatic site and p53 primary tumor expression in previously untreated stage IV breast cancer patients.

Paradiso A, Tommasi S, Barletta A, Leone B, Lacava J, Vellejo C, Labriola A, Marzullo F, Altieri R, Schittulli F, De Lena M.

Anticancer Res. 1999 Sep-Oct;19(5C):4523-8.

PMID:
10650804
44.

Vinorelbine and paclitaxel as first-line chemotherapy in metastatic breast cancer.

Romero Acuña L, Langhi M, Pérez J, Romero Acuña J, Machiavelli M, Lacava J, Vallejo C, Romero A, Fasce H, Ortiz E, Grasso S, Amato S, Rodríguez R, Barbieri M, Leone B.

J Clin Oncol. 1999 Jan;17(1):74-81.

PMID:
10458220
45.

Biochemical modulation of 5-fluorouracil by methotrexate in patients with advanced gastric carcinoma.

Pérez JE, Lacava JA, Dominguez ME, Rodriguez R, Barbieri MR, Ortiz EH, Romero Acuña LA, Langhi MJ, Romero Acuña JM, Vallejo CT, Leone BA, Machiavelli MR, Romero AO.

Am J Clin Oncol. 1998 Oct;21(5):452-7.

PMID:
9781598
46.

Biomodulation with sequential intravenous IFN-alpha2b and 5-fluorouracil as second-line treatment in patients with advanced colorectal cancer.

Pérez JE, Lacava JA, Domínguez ME, Rodríguez R, Barbieri MR, Romero Acuña LA, Romero Acuña JM, Langhi MJ, Amato S, Marrone N, Ortiz EH, Leone BA, Vallejo CT, Machiavelli MR, Romero AO.

J Interferon Cytokine Res. 1998 Aug;18(8):565-9.

PMID:
9726437
47.

Prognostic significance of pathological response of primary tumor and metastatic axillary lymph nodes after neoadjuvant chemotherapy for locally advanced breast carcinoma.

Machiavelli MR, Romero AO, Pérez JE, Lacava JA, Domínguez ME, Rodríguez R, Barbieri MR, Romero Acuña LA, Romero Acuña JM, Langhi MJ, Amato S, Ortiz EH, Vallejo CT, Leone BA.

Cancer J Sci Am. 1998 Mar-Apr;4(2):125-31.

PMID:
9554929
48.

Double modulation of 5-fluorouracil by methotrexate and high-dose L-leucovorin in advanced colorectal cancer.

Romero AO, Perez JE, Cuevas MA, Lacava JA, Sabatini CL, Dominguez ME, Rodriguez R, Barbieri MR, Ortiz EH, Salvadori MA, Acuña LA, Acuña JM, Langhi MJ, Amato S, Machiavelli MR, Leone BA, Vallejo CT, Lorusso V, DeLena M.

Am J Clin Oncol. 1998 Feb;21(1):94-8.

PMID:
9499269
49.

Epidemiology of thrombotic-hemostatic factors and their associations with cardiovascular disease.

Pearson TA, LaCava J, Weil HF.

Am J Clin Nutr. 1997 May;65(5 Suppl):1674S-1682S. doi: 10.1093/ajcn/65.5.1674S. Review.

PMID:
9129509
50.

Vinorelbine as neoadjuvant chemotherapy in advanced cervical carcinoma.

Lacava JA, Leone BA, Machiavelli M, Romero AO, Perez JE, Elem YL, Ferreyra R, Focaccia G, Suttora G, Salvadori MA, Cuevas MA, Acuña LR, Acuña JR, Langhi M, Amato S, Castaldi J, Arroyo A, Vallejo CT.

J Clin Oncol. 1997 Feb;15(2):604-9.

PMID:
9053483

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