Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 76

1.

Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.

Eichler T, Bender K, Murtha MJ, Schwartz L, Metheny J, Solden L, Jaggers RM, Bailey MT, Gupta S, Mosquera C, Ching C, La Perle K, Li B, Becknell B, Spencer JD.

J Am Soc Nephrol. 2019 Jun 25. pii: ASN.2018090929. doi: 10.1681/ASN.2018090929. [Epub ahead of print]

PMID:
31239387
2.

Machine Learning and Veterinary Pathology: Be Not Afraid!

La Perle KMD.

Vet Pathol. 2019 Jul;56(4):506-507. doi: 10.1177/0300985819848504. No abstract available.

PMID:
31185880
3.

MAPK- and AKT-activated thyroid cancers are sensitive to group I PAK inhibition.

Knippler CM, Saji M, Rajan N, Porter K, La Perle K, Ringel MD.

Endocr Relat Cancer. 2019 May 1. pii: ERC-19-0188.R1. doi: 10.1530/ERC-19-0188. [Epub ahead of print]

PMID:
31146260
4.

Pathology Principles and Practices for Analysis of Animal Models.

Knoblaugh SE, Hohl TM, La Perle KMD.

ILAR J. 2019 May 4. pii: ilz001. doi: 10.1093/ilar/ilz001. [Epub ahead of print]

PMID:
31053847
5.

Pathology of wild Norway rats in Vancouver, Canada.

Rothenburger JL, Himsworth CG, La Perle KMD, Leighton FA, Nemeth NM, Treuting PM, Jardine CM.

J Vet Diagn Invest. 2019 Mar;31(2):184-199. doi: 10.1177/1040638719833436.

PMID:
30852980
6.

Comparative Pathologists: Ultimate Control Freaks Seeking Validation!

La Perle KMD.

Vet Pathol. 2019 Jan;56(1):19-23. doi: 10.1177/0300985818806047. Epub 2018 Oct 28.

PMID:
30370836
7.

Genetic ablation of interacting with Spt6 (Iws1) causes early embryonic lethality.

Orlacchio A, Stark AE, Foray C, Amari F, Sheetz T, Reese E, Tessari A, La Perle K, Palmieri D, Tsichlis PN, Coppola V.

PLoS One. 2018 Sep 12;13(9):e0201030. doi: 10.1371/journal.pone.0201030. eCollection 2018.

8.

Alterations in Sod2-Induced Oxidative Stress Affect Endocrine Cancer Progression.

Ashtekar A, Huk D, Magner A, La Perle KMD, Boucai L, Kirschner LS.

J Clin Endocrinol Metab. 2018 Nov 1;103(11):4135-4145. doi: 10.1210/jc.2018-01039.

PMID:
30165401
9.

RANBP9 affects cancer cells response to genotoxic stress and its overexpression is associated with worse response to platinum in NSCLC patients.

Tessari A, Parbhoo K, Pawlikowski M, Fassan M, Rulli E, Foray C, Fabbri A, Embrione V, Ganzinelli M, Capece M, Campbell MJ, Broggini M, La Perle K, Farina G, Cole S, Marabese M, Hernandez M, Amann JM, Pruneri G, Carbone DP, Garassino MC, Croce CM, Palmieri D, Coppola V.

Oncogene. 2018 Dec;37(50):6463-6476. doi: 10.1038/s41388-018-0424-8. Epub 2018 Aug 3.

PMID:
30076413
10.

Deletion of PPARγ in lung macrophages provides an immunoprotective response against M. tuberculosis infection in mice.

Guirado E, Rajaram MV, Chawla A, Daigle J, La Perle KM, Arnett E, Turner J, Schlesinger LS.

Tuberculosis (Edinb). 2018 Jul;111:170-177. doi: 10.1016/j.tube.2018.06.012. Epub 2018 Jun 21.

11.

Deletion of Rap1b, but not Rap1a or Epac1, Reduces Protein Kinase A-Mediated Thyroid Cancer.

Huk DJ, Ashtekar A, Magner A, La Perle K, Kirschner LS.

Thyroid. 2018 Sep;28(9):1153-1161. doi: 10.1089/thy.2017.0528. Epub 2018 Aug 2.

PMID:
29882482
12.
13.

Role of Wild-type and Recombinant Human T-cell Leukemia Viruses in Lymphoproliferative Disease in Humanized NSG Mice.

Huey DD, Bolon B, La Perle KMD, Kannian P, Jacobson S, Ratner L, Green PL, Niewiesk S.

Comp Med. 2018 Feb 1;68(1):4-14.

14.

Intratumoral Delivery of Interferonγ-Secreting Mesenchymal Stromal Cells Repolarizes Tumor-Associated Macrophages and Suppresses Neuroblastoma Proliferation In Vivo.

Relation T, Yi T, Guess AJ, La Perle K, Otsuru S, Hasgur S, Dominici M, Breuer C, Horwitz EM.

Stem Cells. 2018 Jun;36(6):915-924. doi: 10.1002/stem.2801. Epub 2018 Feb 27.

15.

BRAFV600E accelerates disease progression and enhances immune suppression in a mouse model of B-cell leukemia.

Tsai YT, Lakshmanan A, Lehman A, Harrington BK, Lucas FM, Tran M, Sass EJ, Long M, Flechtner AD, Jaynes F, La Perle K, Coppola V, Lozanski G, Muthusamy N, Byrd JC, Grever MR, Lucas DM.

Blood Adv. 2017 Oct 30;1(24):2147-2160. doi: 10.1182/bloodadvances.2017006593. eCollection 2017 Nov 14.

16.

Sdhd ablation promotes thyroid tumorigenesis by inducing a stem-like phenotype.

Ashtekar A, Huk D, Magner A, La Perle K, Zhang X, Piruat JI, López-Barneo J, Jhiang SM, Kirschner LS.

Endocr Relat Cancer. 2017 Nov;24(11):579-591. doi: 10.1530/ERC-17-0229. Epub 2017 Sep 19.

17.

A novel mouse model of rhabdomyosarcoma underscores the dichotomy of MDM2-ALT1 function in vivo.

Comiskey DF Jr, Jacob AG, Sanford BL, Montes M, Goodwin AK, Steiner H, Matsa E, Tapia-Santos AS, Bebee TW, Grieves J, La Perle K, Boyaka P, Chandler DS.

Oncogene. 2018 Jan 4;37(1):95-106. doi: 10.1038/onc.2017.282. Epub 2017 Sep 11.

18.

Safety Profile of Good Manufacturing Practice Manufactured Interferon γ-Primed Mesenchymal Stem/Stromal Cells for Clinical Trials.

Guess AJ, Daneault B, Wang R, Bradbury H, La Perle KMD, Fitch J, Hedrick SL, Hamelberg E, Astbury C, White P, Overolt K, Rangarajan H, Abu-Arja R, Devine SM, Otsuru S, Dominici M, O'Donnell L, Horwitz EM.

Stem Cells Transl Med. 2017 Oct;6(10):1868-1879. doi: 10.1002/sctm.16-0485. Epub 2017 Sep 9.

19.

RCAN1-4 is a thyroid cancer growth and metastasis suppressor.

Wang C, Saji M, Justiniano SE, Yusof AM, Zhang X, Yu L, Fernández S, Wakely P Jr, La Perle K, Nakanishi H, Pohlman N, Ringel MD.

JCI Insight. 2017 Mar 9;2(5):e90651. doi: 10.1172/jci.insight.90651.

20.

KTN0158, a Humanized Anti-KIT Monoclonal Antibody, Demonstrates Biologic Activity against both Normal and Malignant Canine Mast Cells.

London CA, Gardner HL, Rippy S, Post G, La Perle K, Crew L, Lopresti-Morrow L, Garton AJ, McMahon G, LaVallee TM, Gedrich R.

Clin Cancer Res. 2017 May 15;23(10):2565-2574. doi: 10.1158/1078-0432.CCR-16-2152. Epub 2016 Nov 4.

21.

Spontaneous reproductive pathology in female guinea pigs.

Veiga-Parga T, La Perle KM, Newman SJ.

J Vet Diagn Invest. 2016 Nov;28(6):656-661. Epub 2016 Oct 3.

PMID:
27701078
22.

Fhit loss-associated initiation and progression of neoplasia in vitro.

Karras JR, Schrock MS, Batar B, Zhang J, La Perle K, Druck T, Huebner K.

Cancer Sci. 2016 Nov;107(11):1590-1598. doi: 10.1111/cas.13032. Epub 2016 Oct 3.

23.

Mechanism, Consequences, and Therapeutic Targeting of Abnormal IL15 Signaling in Cutaneous T-cell Lymphoma.

Mishra A, La Perle K, Kwiatkowski S, Sullivan LA, Sams GH, Johns J, Curphey DP, Wen J, McConnell K, Qi J, Wong H, Russo G, Zhang J, Marcucci G, Bradner JE, Porcu P, Caligiuri MA.

Cancer Discov. 2016 Sep;6(9):986-1005. doi: 10.1158/2159-8290.CD-15-1297. Epub 2016 Jul 15.

24.

Evaluation of a bilayered, micropatterned hydrogel dressing for full-thickness wound healing.

Magin CM, Neale DB, Drinker MC, Willenberg BJ, Reddy ST, La Perle KM, Schultz GS, Brennan AB.

Exp Biol Med (Maywood). 2016 May;241(9):986-95. doi: 10.1177/1535370216640943. Epub 2016 Mar 31.

25.

NK Cell-Mediated Antitumor Effects of a Folate-Conjugated Immunoglobulin Are Enhanced by Cytokines.

Jaime-Ramirez AC, McMichael E, Kondadasula S, Skinner CC, Mundy-Bosse BL, Luedke E, Jones NB, Mani A, Roda J, Karpa V, Li H, Li J, Elavazhagan S, La Perle KM, Schmitt AC, Lu Y, Zhang X, Pan X, Mao H, Davis M, Jarjoura D, Butchar JP, Poi M, Phelps M, Tridandapani S, Byrd JC, Caligiuri MA, Lee RJ, Carson WE 3rd.

Cancer Immunol Res. 2016 Apr;4(4):323-336. doi: 10.1158/2326-6066.CIR-15-0168. Epub 2016 Feb 10.

26.

Noncatalytic PTEN missense mutation predisposes to organ-selective cancer development in vivo.

Caserta E, Egriboz O, Wang H, Martin C, Koivisto C, Pecót T, Kladney RD, Shen C, Shim KS, Pham T, Karikomi MK, Mauntel MJ, Majumder S, Cuitino MC, Tang X, Srivastava A, Yu L, Wallace J, Mo X, Park M, Fernandez SA, Pilarski R, La Perle KM, Rosol TJ, Coppola V, Castrillon DH, Timmers C, Cohn DE, O'Malley DM, Backes F, Suarez AA, Goodfellow P, Chamberlin HM, Macrae ER, Shapiro CL, Ostrowski MC, Leone G.

Genes Dev. 2015 Aug 15;29(16):1707-20. doi: 10.1101/gad.262568.115.

27.

Endogenous Retinoic Acid Required to Maintain the Epidermis Following Ultraviolet Light Exposure in SKH-1 Hairless Mice.

Gressel KL, Duncan FJ, Oberyszyn TM, La Perle KM, Everts HB.

Photochem Photobiol. 2015 Jul-Aug;91(4):901-8. doi: 10.1111/php.12441. Epub 2015 Mar 28.

28.

Trophoblast deportation to the lungs of cotton rats (Sigmodon hispidus).

La Perle KM, Green MG, Niewiesk S.

Comp Med. 2014 Dec;64(6):448-55.

29.

Novel small molecule XPO1/CRM1 inhibitors induce nuclear accumulation of TP53, phosphorylated MAPK and apoptosis in human melanoma cells.

Yang J, Bill MA, Young GS, La Perle K, Landesman Y, Shacham S, Kauffman M, Senapedis W, Kashyap T, Saint-Martin JR, Kendra K, Lesinski GB.

PLoS One. 2014 Jul 24;9(7):e102983. doi: 10.1371/journal.pone.0102983. eCollection 2014.

30.

Extra-prostatic transgene-associated neoplastic lesions in transgenic adenocarcinoma of the mouse prostate (TRAMP) mice.

Berman-Booty LD, Thomas-Ahner JM, Bolon B, Oglesbee MJ, Clinton SK, Kulp SK, Chen CS, La Perle KM.

Toxicol Pathol. 2015 Feb;43(2):186-97. doi: 10.1177/0192623314531351. Epub 2014 Apr 17.

31.

Feasibility and safety of systemic rAAV9-hNAGLU delivery for treating mucopolysaccharidosis IIIB: toxicology, biodistribution, and immunological assessments in primates.

Murrey DA, Naughton BJ, Duncan FJ, Meadows AS, Ware TA, Campbell KJ, Bremer WG, Walker CM, Goodchild L, Bolon B, La Perle K, Flanigan KM, McBride KL, McCarty DM, Fu H.

Hum Gene Ther Clin Dev. 2014 Jun;25(2):72-84. doi: 10.1089/humc.2013.208. Epub 2014 Apr 10.

32.

Visualization of extracellular matrix components within sectioned Salmonella biofilms on the surface of human gallstones.

Marshall JM, Flechtner AD, La Perle KM, Gunn JS.

PLoS One. 2014 Feb 14;9(2):e89243. doi: 10.1371/journal.pone.0089243. eCollection 2014.

33.

Follicular thyroid cancers demonstrate dual activation of PKA and mTOR as modeled by thyroid-specific deletion of Prkar1a and Pten in mice.

Pringle DR, Vasko VV, Yu L, Manchanda PK, Lee AA, Zhang X, Kirschner JM, Parlow AF, Saji M, Jarjoura D, Ringel MD, La Perle KM, Kirschner LS.

J Clin Endocrinol Metab. 2014 May;99(5):E804-12. doi: 10.1210/jc.2013-3101. Epub 2014 Feb 10.

34.

Histopathological analysis of Salmonella chronic carriage in the mouse hepatopancreatobiliary system.

Gonzalez-Escobedo G, La Perle KM, Gunn JS.

PLoS One. 2013 Dec 12;8(12):e84058. doi: 10.1371/journal.pone.0084058. eCollection 2013.

35.

'Reduced malignancy as a mechanism for longevity in mice with adenylyl cyclase type 5 disruption'.

De Lorenzo MS, Chen W, Baljinnyam E, Carlini MJ, La Perle K, Bishop SP, Wagner TE, Rabson AB, Vatner DE, Puricelli LI, Vatner SF.

Aging Cell. 2014 Feb;13(1):102-10. doi: 10.1111/acel.12152. Epub 2013 Oct 13.

36.

Modulation of sodium/iodide symporter expression in the salivary gland.

La Perle KM, Kim DC, Hall NC, Bobbey A, Shen DH, Nagy RS, Wakely PE Jr, Lehman A, Jarjoura D, Jhiang SM.

Thyroid. 2013 Aug;23(8):1029-36. doi: 10.1089/thy.2012.0571. Epub 2013 Jul 17.

37.

Rac1 is required for Prkar1a-mediated Nf2 suppression in Schwann cell tumors.

Manchanda PK, Jones GN, Lee AA, Pringle DR, Zhang M, Yu L, La Perle KM, Kirschner LS.

Oncogene. 2013 Jul 25;32(30):3491-9. doi: 10.1038/onc.2012.374. Epub 2012 Oct 8.

38.

Patterns of scAAV vector insertion associated with oncogenic events in a mouse model for genotoxicity.

Rosas LE, Grieves JL, Zaraspe K, La Perle KM, Fu H, McCarty DM.

Mol Ther. 2012 Nov;20(11):2098-110. doi: 10.1038/mt.2012.197. Epub 2012 Sep 18.

39.

Essential metabolic, anti-inflammatory, and anti-tumorigenic functions of miR-122 in liver.

Hsu SH, Wang B, Kota J, Yu J, Costinean S, Kutay H, Yu L, Bai S, La Perle K, Chivukula RR, Mao H, Wei M, Clark KR, Mendell JR, Caligiuri MA, Jacob ST, Mendell JT, Ghoshal K.

J Clin Invest. 2012 Aug;122(8):2871-83. doi: 10.1172/JCI63539. Epub 2012 Jul 23.

40.

Thyroid-specific ablation of the Carney complex gene, PRKAR1A, results in hyperthyroidism and follicular thyroid cancer.

Pringle DR, Yin Z, Lee AA, Manchanda PK, Yu L, Parlow AF, Jarjoura D, La Perle KM, Kirschner LS.

Endocr Relat Cancer. 2012 May 24;19(3):435-46. doi: 10.1530/ERC-11-0306. Print 2012 Jun.

41.

The effect of intravitreal anti-VEGF agents on peripheral wound healing in a rabbit model.

Christoforidis J, Ricketts R, Pratt C, Pierce J, Bean S, Wells M, Zhang X, La Perle K.

Clin Ophthalmol. 2012;6:61-9. doi: 10.2147/OPTH.S28275. Epub 2012 Jan 10.

42.

A prostate fibromyxoid sarcoma with smooth muscle differentiation in a F344xBNF1 rat.

Berman-Booty LD, Garzel LM, Bergdall V, La Perle KM.

Vet Pathol. 2012 Jul;49(4):642-7. doi: 10.1177/0300985811429310. Epub 2012 Jan 18.

PMID:
22262352
43.

Preclinical validation of AR42, a novel histone deacetylase inhibitor, as treatment for vestibular schwannomas.

Jacob A, Oblinger J, Bush ML, Brendel V, Santarelli G, Chaudhury AR, Kulp S, La Perle KM, Chen CS, Chang LS, Welling DB.

Laryngoscope. 2012 Jan;122(1):174-89. doi: 10.1002/lary.22392. Epub 2011 Nov 22.

44.

Myeloid-derived suppressor cell inhibition of the IFN response in tumor-bearing mice.

Mundy-Bosse BL, Lesinski GB, Jaime-Ramirez AC, Benninger K, Khan M, Kuppusamy P, Guenterberg K, Kondadasula SV, Chaudhury AR, La Perle KM, Kreiner M, Young G, Guttridge DC, Carson WE 3rd.

Cancer Res. 2011 Aug 1;71(15):5101-10. doi: 10.1158/0008-5472.CAN-10-2670. Epub 2011 Jun 16.

45.

Akt1 deficiency delays tumor progression, vascular invasion, and distant metastasis in a murine model of thyroid cancer.

Saji M, Narahara K, McCarty SK, Vasko VV, La Perle KM, Porter K, Jarjoura D, Lu C, Cheng SY, Ringel MD.

Oncogene. 2011 Oct 20;30(42):4307-15. doi: 10.1038/onc.2011.136. Epub 2011 May 2.

46.

Advancing translational research.

Bolon B, Altrock B, Barthold SW, Baumgarth N, Besselsen D, Boivin G, Boyd KL, Brayton C, Cardiff RD, Couto S, Eaton KA, Foreman O, Griffey SM, La Perle K, Lairmore MD, Liu C, Meyerholz DK, Nikitin AY, Schoeb TR, Schwahn D, Sellers RS, Sundberg JP, Tolwani R, Valli VE, Zink MC.

Science. 2011 Mar 25;331(6024):1516-7. doi: 10.1126/science.331.6024.1516-b. No abstract available.

PMID:
21436422
47.

Cox-2 expression, PGE(2) and cytokines production are inhibited by endogenously synthesized n-3 PUFAs in inflamed colon of fat-1 mice.

Gravaghi C, La Perle KM, Ogrodwski P, Kang JX, Quimby F, Lipkin M, Lamprecht SA.

J Nutr Biochem. 2011 Apr;22(4):360-5. doi: 10.1016/j.jnutbio.2010.03.003. Epub 2010 Jul 23.

PMID:
20655721
48.

Targeted deletion of Kcne2 causes gastritis cystica profunda and gastric neoplasia.

Roepke TK, Purtell K, King EC, La Perle KM, Lerner DJ, Abbott GW.

PLoS One. 2010 Jul 6;5(7):e11451. doi: 10.1371/journal.pone.0011451.

49.

Neural crest-specific loss of Prkar1a causes perinatal lethality resulting from defects in intramembranous ossification.

Jones GN, Pringle DR, Yin Z, Carlton MM, Powell KA, Weinstein MB, Toribio RE, La Perle KM, Kirschner LS.

Mol Endocrinol. 2010 Aug;24(8):1559-68. doi: 10.1210/me.2009-0439. Epub 2010 Jun 9.

50.

Allele-specific tumor spectrum in pten knockin mice.

Wang H, Karikomi M, Naidu S, Rajmohan R, Caserta E, Chen HZ, Rawahneh M, Moffitt J, Stephens JA, Fernandez SA, Weinstein M, Wang D, Sadee W, La Perle K, Stromberg P, Rosol TJ, Eng C, Ostrowski MC, Leone G.

Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5142-7. doi: 10.1073/pnas.0912524107. Epub 2010 Mar 1.

Supplemental Content

Loading ...
Support Center