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Fully Integrated and Foldable Microdevice Encapsulated with Agarose for Long-Term Storage Potential for Point-of-Care Testing of Multiplex Foodborne Pathogens.

Trinh TND, La HC, Lee NY.

ACS Sens. 2019 Sep 24. doi: 10.1021/acssensors.9b01299. [Epub ahead of print]


Characterization and fine mapping of Arabidopsis RLL3, a locus required for DNA demethylation pathway.

Miao W, Dai J, La Y, Lu C, Zhang J, Hong X, Zhou S, Wang Q, Wang X, Rui Q, Tan F, La H.

Mol Genet Genomics. 2019 Sep 5. doi: 10.1007/s00438-019-01605-4. [Epub ahead of print]


Severe Cutaneous Adverse Reactions to Antiepileptic Drugs: A Nationwide Registry-Based Study in Korea.

Park CS, Kang DY, Kang MG, Kim S, Ye YM, Kim SH, Park HK, Park JW, Nam YH, Yang MS, Jee YK, Jung JW, Kim SH, Kim CW, Kim MY, Kim JH, Lee J, Lee JG, Kim SH, La HO, Kim MH, Park SJ, Koh YI, Lee SM, Kwon YE, Jin HJ, Kim HK, Kang HR, Choi JH; Korean Registry of Severe Cutaneous Adverse Reactions Consortium.

Allergy Asthma Immunol Res. 2019 Sep;11(5):709-722. doi: 10.4168/aair.2019.11.5.709.


Zooplankton and micronekton respond to climate fluctuations in the Amundsen Sea polynya, Antarctica.

La HS, Park K, Wåhlin A, Arrigo KR, Kim DS, Yang EJ, Atkinson A, Fielding S, Im J, Kim TW, Shin HC, Lee S, Ha HK.

Sci Rep. 2019 Jul 12;9(1):10087. doi: 10.1038/s41598-019-46423-1.


Mechanisms regulating mammalian spermatogenesis and fertility recovery following germ cell depletion.

La HM, Hobbs RM.

Cell Mol Life Sci. 2019 Oct;76(20):4071-4102. doi: 10.1007/s00018-019-03201-6. Epub 2019 Jun 28. Review.


DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia.

Legrand JMD, Chan AL, La HM, Rossello FJ, Änkö ML, Fuller-Pace FV, Hobbs RM.

Nat Commun. 2019 May 23;10(1):2278. doi: 10.1038/s41467-019-09972-7.


Estimating the size of key populations for HIV in Singapore using the network scale-up method.

Teo AKJ, Prem K, Chen MIC, Roellin A, Wong ML, La HH, Cook AR.

Sex Transm Infect. 2019 May 9. pii: sextrans-2018-053747. doi: 10.1136/sextrans-2018-053747. [Epub ahead of print]


WITHDRAWN: Performance of survivin mRNA as a biomarker for breast cancer among Vietnamese women.

Nguyen HM, Dao MQ, La HT.

Breast Dis. 2019 Mar 26. doi: 10.3233/BD-180374. [Epub ahead of print]


Performance of survivin mRNA as a biomarker for breast cancer among Vietnamese women.

Nguyen HM, Dao MQ, La HT.

Heliyon. 2019 Mar 20;5(3):e01371. doi: 10.1016/j.heliyon.2019.e01371. eCollection 2019 Mar.


Simultaneous Bilateral Primary Spontaneous Pneumothorax: A Case Report and a Review of the Literature.

Kewcharoen J, Morris P, Kanitsoraphan C, La H, Sriratanaviriyakul N.

Case Rep Pulmonol. 2019 Jan 27;2019:6583842. doi: 10.1155/2019/6583842. eCollection 2019.


Phenotypes of Severe Cutaneous Adverse Reactions Caused by Nonsteroidal Anti-inflammatory Drugs.

Lee SY, Nam YH, Koh YI, Kim SH, Kim S, Kang HR, Kim MH, Lee JG, Park JW, Park HK, La HO, Kim MY, Park SJ, Kwon YE, Jung JW, Kim SH, Kim CW, Yang MS, Kang MG, Lee JY, Kim JH, Kim SH, Hur GY, Jee YK, Jin HJ, Park CS, Jeong YY, Ye YM.

Allergy Asthma Immunol Res. 2019 Mar;11(2):212-221. doi: 10.4168/aair.2019.11.2.212.


Cyclodextrin Reduces Intravenous Toxicity of a Model Compound.

Mantik P, Xie M, Wong H, La H, Steigerwalt RW, Devanaboyina U, Ganem G, Shih D, Flygare JA, Fairbrother WJ, Chakravarty P, Russell D, Fernandez GE, Narang AS.

J Pharm Sci. 2019 Jun;108(6):1934-1943. doi: 10.1016/j.xphs.2019.01.004. Epub 2019 Jan 11.


The influence of biochar and compost mixtures, water content, and gas flow rate, on the continuous adsorption of methane in a fixed bed column.

La H, Hettiaratchi JPA, Achari G.

J Environ Manage. 2019 Mar 1;233:175-183. doi: 10.1016/j.jenvman.2018.12.015. Epub 2018 Dec 20.


Roles of CRWN-family proteins in protecting genomic DNA against oxidative damage.

Wang Q, Liu S, Lu C, La Y, Dai J, Ma H, Zhou S, Tan F, Wang X, Wu Y, Kong W, La H.

J Plant Physiol. 2019 Feb;233:20-30. doi: 10.1016/j.jplph.2018.12.005. Epub 2018 Dec 13.


Development of a self-guided web-based intervention to promote physical activity using the multi-process action control framework.

Liu S, Husband C, La H, Juba M, Loucks R, Harrison A, Rhodes RE.

Internet Interv. 2018 Dec 4;15:35-42. doi: 10.1016/j.invent.2018.11.003. eCollection 2019 Mar.


Stress, Satisfaction, and Competency of Hospital Pharmacy Preceptors under the New Pharmacy Program in South Korea.

Seo H, Ryu K, Lee S, Noh J, La H, Kim E.

Am J Pharm Educ. 2018 Oct;82(8):6351. doi: 10.5688/ajpe6351.


Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors.

Yen I, Shanahan F, Merchant M, Orr C, Hunsaker T, Durk M, La H, Zhang X, Martin SE, Lin E, Chan J, Yu Y, Amin D, Neve RM, Gustafson A, Venkatanarayan A, Foster SA, Rudolph J, Klijn C, Malek S.

Cancer Cell. 2018 Oct 8;34(4):611-625.e7. doi: 10.1016/j.ccell.2018.09.002.


Temporal relationship between occurrences of hand, foot and mouth disease, respiratory virus detection and febrile seizures in children in tropical Singapore: a time-series analysis.

Chen Y, Chong CY, Cook AR, Sim NTW, Horby P, La HH.

Epidemiol Infect. 2018 Sep 13:1-6. doi: 10.1017/S0950268818002509. [Epub ahead of print]


GILZ-dependent modulation of mTORC1 regulates spermatogonial maintenance.

La HM, Chan AL, Legrand JMD, Rossello FJ, Gangemi CG, Papa A, Cheng Q, Morand EF, Hobbs RM.

Development. 2018 Sep 18;145(18). pii: dev165324. doi: 10.1242/dev.165324.


A mixed methods study of non-occupational post-exposure prophylaxis at an STI clinic in Singapore: Five-year retrospective analysis and providers' perspectives.

Teo AKJ, Tai BC, Chio MT, La HH.

PLoS One. 2018 Aug 20;13(8):e0202267. doi: 10.1371/journal.pone.0202267. eCollection 2018.


Biofiltration of methane.

La H, Hettiaratchi JPA, Achari G, Dunfield PF.

Bioresour Technol. 2018 Nov;268:759-772. doi: 10.1016/j.biortech.2018.07.043. Epub 2018 Jul 10. Review.


Identification of dynamic undifferentiated cell states within the male germline.

La HM, Mäkelä JA, Chan AL, Rossello FJ, Nefzger CM, Legrand JMD, De Seram M, Polo JM, Hobbs RM.

Nat Commun. 2018 Jul 19;9(1):2819. doi: 10.1038/s41467-018-04827-z.


Supplementation of guanidinoacetic acid to pig diets: effects on performance, carcass characteristics, and meat quality.

Jayaraman B, La KV, La H, Doan V, Carpena EM, Rademacher M, Channarayapatna G.

J Anim Sci. 2018 Jun 4;96(6):2332-2341. doi: 10.1093/jas/sky137.


Arabidopsis subtilase SASP is involved in the regulation of ABA signaling and drought tolerance by interacting with OPEN STOMATA 1.

Wang Q, Guo Q, Guo Y, Yang J, Wang M, Duan X, Niu J, Liu S, Zhang J, Lu Y, Hou Z, Miao W, Wang X, Kong W, Xu X, Wu Y, Rui Q, La H.

J Exp Bot. 2018 Aug 14;69(18):4403-4417. doi: 10.1093/jxb/ery205.


Biofiltration of methane using hybrid mixtures of biochar, lava rock and compost.

La H, Hettiaratchi JPA, Achari G, Verbeke TJ, Dunfield PF.

Environ Pollut. 2018 Oct;241:45-54. doi: 10.1016/j.envpol.2018.05.039. Epub 2018 May 21.


Severity and burden of hand, foot and mouth disease in Asia: a modelling study.

Koh WM, Badaruddin H, La H, Chen MI, Cook AR.

BMJ Glob Health. 2018 Jan 26;3(1):e000442. doi: 10.1136/bmjgh-2017-000442. eCollection 2018.


Analysis of the DNA methylation patterns and transcriptional regulation of the NB-LRR-encoding gene family in Arabidopsis thaliana.

Kong W, Li B, Wang Q, Wang B, Duan X, Ding L, Lu Y, Liu LW, La H.

Plant Mol Biol. 2018 Apr;96(6):563-575. doi: 10.1007/s11103-018-0715-z. Epub 2018 Mar 10.


Endothelium Independent Effect of Pelargonidin on Vasoconstriction in Rat Aorta.

Min YS, Yoon HJ, Je HD, Lee JH, Yoo SS, Shim HS, Lee HY, La HO, Sohn UD.

Biomol Ther (Seoul). 2018 Jul 1;26(4):374-379. doi: 10.4062/biomolther.2017.197.


Germline Stem Cell Activity Is Sustained by SALL4-Dependent Silencing of Distinct Tumor Suppressor Genes.

Chan AL, La HM, Legrand JMD, Mäkelä JA, Eichenlaub M, De Seram M, Ramialison M, Hobbs RM.

Stem Cell Reports. 2017 Sep 12;9(3):956-971. doi: 10.1016/j.stemcr.2017.08.001. Epub 2017 Aug 31.


Light intensity as major factor to maximize biomass and lipid productivity of Ettlia sp. in CO2-controlled photoautotrophic chemostat.

Seo SH, Ha JS, Yoo C, Srivastava A, Ahn CY, Cho DH, La HJ, Han MS, Oh HM.

Bioresour Technol. 2017 Nov;244(Pt 1):621-628. doi: 10.1016/j.biortech.2017.08.020. Epub 2017 Aug 7.


The impact of hand, foot and mouth disease control policies in Singapore: A qualitative analysis of public perceptions.

Siegel K, Cook AR, La H.

J Public Health Policy. 2017 May;38(2):271-287. doi: 10.1057/s41271-017-0066-z.


Hypothermia Inhibits Endothelium-Independent Vascular Contractility via Rho-kinase Inhibition.

Chung YH, Oh KW, Kim ST, Park ES, Je HD, Yoon HJ, Sohn UD, Jeong JH, La HO.

Biomol Ther (Seoul). 2018 Mar 1;26(2):139-145. doi: 10.4062/biomolther.2016.233.


SAC3B, a central component of the mRNA export complex TREX-2, is required for prevention of epigenetic gene silencing in Arabidopsis.

Yang Y, La H, Tang K, Miki D, Yang L, Wang B, Duan CG, Nie W, Wang X, Wang S, Pan Y, Tran EJ, An L, Zhang H, Zhu JK.

Nucleic Acids Res. 2017 Jan 9;45(1):181-197. doi: 10.1093/nar/gkw850. Epub 2016 Sep 26.


Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor.

Chan BK, Hanan EJ, Bowman KK, Bryan MC, Burdick D, Chan E, Chen Y, Clausen S, Dela Vega T, Dotson J, Eigenbrot C, Elliott RL, Heald RA, Jackson PS, Knight JD, La H, Lainchbury MD, Malek S, Purkey HE, Schaefer G, Schmidt S, Seward EM, Sideris S, Shao L, Wang S, Yeap SK, Yen I, Yu C, Heffron TP.

J Med Chem. 2016 Oct 13;59(19):9080-9093. Epub 2016 Sep 12.


Discovery of oxa-sultams as RORc inverse agonists showing reduced lipophilicity, improved selectivity and favorable ADME properties.

René O, Fauber BP, Barnard A, Chapman K, Deng Y, Eidenschenk C, Everett C, Gobbi A, Johnson AR, La H, Norman M, Salmon G, Summerhill S, Wong H.

Bioorg Med Chem Lett. 2016 Sep 15;26(18):4455-4461. doi: 10.1016/j.bmcl.2016.07.081. Epub 2016 Aug 3.


Chronic eosinophilic pneumonia presenting with ipsilateral pleural effusion: a case report.

Sriratanaviriyakul N, La HH, Albertson TE.

J Med Case Rep. 2016 Aug 12;10(1):227. doi: 10.1186/s13256-016-1005-5.


Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors.

Lee W, Crawford JJ, Aliagas I, Murray LJ, Tay S, Wang W, Heise CE, Hoeflich KP, La H, Mathieu S, Mintzer R, Ramaswamy S, Rouge L, Rudolph J.

Bioorg Med Chem Lett. 2016 Aug 1;26(15):3518-24. doi: 10.1016/j.bmcl.2016.06.031. Epub 2016 Jun 15.


Chemically Diverse Group I p21-Activated Kinase (PAK) Inhibitors Impart Acute Cardiovascular Toxicity with a Narrow Therapeutic Window.

Rudolph J, Murray LJ, Ndubaku CO, O'Brien T, Blackwood E, Wang W, Aliagas I, Gazzard L, Crawford JJ, Drobnick J, Lee W, Zhao X, Hoeflich KP, Favor DA, Dong P, Zhang H, Heise CE, Oh A, Ong CC, La H, Chakravarty P, Chan C, Jakubiak D, Epler J, Ramaswamy S, Vega R, Cain G, Diaz D, Zhong Y.

J Med Chem. 2016 Jun 9;59(11):5520-41. doi: 10.1021/acs.jmedchem.6b00638. Epub 2016 May 24.


Rate-Determining and Rate-Limiting Steps in the Clearance and Excretion of a Potent and Selective p21-Activated Kinase Inhibitor: A Case Study of Rapid Hepatic Uptake and Slow Elimination in Rat.

Fan PW, Chen JZ, Allan Jaochico M, La H, Liu N, Mulder T, Cass RT, Durk M, Messick K, Valle N, Liu S, Lee W, Crawford JJ, Rudolf J, Murray LJ, Cyrus Khojasteh S, Wright M.

Drug Metab Lett. 2016;10(2):91-100.


Correction to Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study.

Heald R, Bowman KK, Bryan MC, Burdick D, Chan B, Chan E, Chen Y, Clausen S, Dominguez-Fernandez B, Eigenbrot C, Elliott R, Hanan EJ, Jackson P, Knight J, La H, Lainchbury M, Malek S, Mann S, Merchant M, Mortara K, Purkey H, Schaefer G, Schmidt S, Seward E, Sideris S, Shao L, Wang S, Yeap K, Yen I, Yu C, Heffron TP.

J Med Chem. 2016 Mar 24;59(6):2848. doi: 10.1021/acs.jmedchem.6b00301. Epub 2016 Mar 11. No abstract available.


Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR.

Bryan MC, Burdick DJ, Chan BK, Chen Y, Clausen S, Dotson J, Eigenbrot C, Elliott R, Hanan EJ, Heald R, Jackson P, La H, Lainchbury M, Malek S, Mann SE, Purkey HE, Schaefer G, Schmidt S, Seward E, Sideris S, Wang S, Yen I, Yu C, Heffron TP.

ACS Med Chem Lett. 2015 Dec 17;7(1):100-4. doi: 10.1021/acsmedchemlett.5b00428. eCollection 2016 Jan 14.


Endothelium-Independent Effect of Fisetin on the Agonist-Induced Regulation of Vascular Contractility.

Je HD, Sohn UD, La HO.

Biomol Ther (Seoul). 2016 Jan;24(1):57-61. doi: 10.4062/biomolther.2015.104. Epub 2016 Jan 1.


Design of Selective PAK1 Inhibitor G-5555: Improving Properties by Employing an Unorthodox Low-pK a Polar Moiety.

Ndubaku CO, Crawford JJ, Drobnick J, Aliagas I, Campbell D, Dong P, Dornan LM, Duron S, Epler J, Gazzard L, Heise CE, Hoeflich KP, Jakubiak D, La H, Lee W, Lin B, Lyssikatos JP, Maksimoska J, Marmorstein R, Murray LJ, O'Brien T, Oh A, Ramaswamy S, Wang W, Zhao X, Zhong Y, Blackwood E, Rudolph J.

ACS Med Chem Lett. 2015 Oct 31;6(12):1241-6. doi: 10.1021/acsmedchemlett.5b00398. eCollection 2015 Dec 10.


4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase.

Hanan EJ, Baumgardner M, Bryan MC, Chen Y, Eigenbrot C, Fan P, Gu XH, La H, Malek S, Purkey HE, Schaefer G, Schmidt S, Sideris S, Yen I, Yu C, Heffron TP.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):534-539. doi: 10.1016/j.bmcl.2015.11.078. Epub 2015 Nov 22.


Upconverting NIR Photons for Bioimaging.

Li Z, Zhang Y, La H, Zhu R, El-Banna G, Wei Y, Han G.

Nanomaterials (Basel). 2015 Dec 4;5(4):2148-2168. doi: 10.3390/nano5042148. Review.


Evaluation of various techniques for microalgal biomass quantification.

Sarrafzadeh MH, La HJ, Seo SH, Asgharnejad H, Oh HM.

J Biotechnol. 2015 Dec 20;216:90-7. doi: 10.1016/j.jbiotec.2015.10.010. Epub 2015 Oct 22.


Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study.

Heald R, Bowman KK, Bryan MC, Burdick D, Chan B, Chan E, Chen Y, Clausen S, Dominguez-Fernandez B, Eigenbrot C, Elliott R, Hanan EJ, Jackson P, Knight J, La H, Lainchbury M, Malek S, Mann S, Merchant M, Mortara K, Purkey H, Schaefer G, Schmidt S, Seward E, Sideris S, Shao L, Wang S, Yeap K, Yen I, Yu C, Heffron TP.

J Med Chem. 2015 Nov 25;58(22):8877-95. doi: 10.1021/acs.jmedchem.5b01412. Epub 2015 Nov 12. Erratum in: J Med Chem. 2016 Mar 24;59(6):2848.


Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists.

Fauber BP, Gobbi A, Savy P, Burton B, Deng Y, Everett C, La H, Johnson AR, Lockey P, Norman M, Wong H.

Bioorg Med Chem Lett. 2015 Oct 1;25(19):4109-13. doi: 10.1016/j.bmcl.2015.08.028. Epub 2015 Aug 14.


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