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Items: 1 to 50 of 90

1.

Comparative study about the performance of three types of modified natural treatment systems for rice noodle wastewater.

Nguyen XC, Chang SW, Tran TCP, Nguyen TTN, Hoang TQ, Banu JR, Al-Muhtaseb AH, La DD, Guo W, Ngo HH, Nguyen DD.

Bioresour Technol. 2019 Jun;282:163-170. doi: 10.1016/j.biortech.2019.02.117. Epub 2019 Feb 28.

PMID:
30861445
2.

Supramolecular Chiral Helical Ribbons of Tetraphenylethylene-Appended Naphthalenediimide Controlled by Solvent and Induced by l- and d-Alanine Spacers.

Goskulwad SP, Kobaisi MA, La DD, Bhosale RS, Ratanlal M, Bhosale SV, Bhosale SV.

Chem Asian J. 2018 Dec 18;13(24):3947-3953. doi: 10.1002/asia.201801421. Epub 2018 Nov 26.

PMID:
30417602
3.

Chiral Supramolecular Assemblies from an Achiral Naphthalene Diimide Bearing a Urea Moiety.

Shaikh DB, Bhosale RS, La DD, Al Kobaisi M, Bhosale SV, Bhosale SV.

Chem Asian J. 2018 Nov 2;13(21):3268-3273. doi: 10.1002/asia.201801115. Epub 2018 Oct 2.

PMID:
30160826
4.

Lead Optimization of 5-Aryl Benzimidazolone- and Oxindole-Based AMPA Receptor Modulators Selective for TARP γ-8.

Ravula S, Savall BM, Wu N, Lord B, Coe K, Wang K, Seierstad M, Swanson DM, Ziff J, Nguyen M, Leung P, Rynberg R, La D, Pippel DJ, Koudriakova T, Lovenberg TW, Carruthers NI, Maher MP, Ameriks MK.

ACS Med Chem Lett. 2018 Jul 13;9(8):821-826. doi: 10.1021/acsmedchemlett.8b00215. eCollection 2018 Aug 9.

PMID:
30128074
5.

Dynamic multistimuli-responsive reversible chiral transformation in supramolecular helices.

Goskulwad S, La DD, Kobaisi MA, Bhosale SV, Bansal V, Vinu A, Ariga K, Bhosale SV.

Sci Rep. 2018 Jul 25;8(1):11220. doi: 10.1038/s41598-018-29152-9.

6.

[Efficacy and safety of low-dose levonorgestrel-releasing intrauterine system in Chinese women: a multicenter, single-arm, open labeled interventional trial].

Qian CF, Fan GS, Liao QP, Wu SY, La DD, Di W, Dong BH, Liu HW, Tang LD, Xiong ZA, Zhang HW, Hu YL, Yang NM, Ren ML, Shi H, Deng GP, Huang ZR.

Zhonghua Fu Chan Ke Za Zhi. 2018 Jun 25;53(6):409-413. doi: 10.3760/cma.j.issn.0529-567x.2018.06.009. Chinese.

PMID:
29961284
7.

1,2,4-Triazolsulfone: A novel isosteric replacement of acylsulfonamides in the context of NaV1.7 inhibition.

Boezio AA, Andrews K, Boezio C, Chu-Moyer M, Copeland KW, DiMauro EF, Foti RS, Fremeau RT Jr, Gao H, Geuns-Meyer S, Graceffa RF, Gunaydin H, Huang H, La DS, Ligutti J, Moyer BD, Peterson EA, Yu V, Weiss MM.

Bioorg Med Chem Lett. 2018 Jun 15;28(11):2103-2108. doi: 10.1016/j.bmcl.2018.04.035. Epub 2018 Apr 17.

PMID:
29709252
8.

Breakthroughs in neuroactive steroid drug discovery.

Blanco MJ, La D, Coughlin Q, Newman CA, Griffin AM, Harrison BL, Salituro FG.

Bioorg Med Chem Lett. 2018 Jan 15;28(2):61-70. doi: 10.1016/j.bmcl.2017.11.043. Epub 2017 Dec 2. Review.

PMID:
29223589
9.

The sensitivity of donor - acceptor charge transfer to molecular geometry in DAN - NDI based supramolecular flower-like self-assemblies.

Kobaisi MA, Bhosale RS, El-Khouly ME, La DD, Padghan SD, Bhosale SV, Jones LA, Antolasic F, Fukuzumi S, Bhosale SV.

Sci Rep. 2017 Nov 28;7(1):16501. doi: 10.1038/s41598-017-15599-9.

10.

Tetraphenylethylene-Based AIE-Active Probes for Sensing Applications.

La DD, Bhosale SV, Jones LA, Bhosale SV.

ACS Appl Mater Interfaces. 2018 Apr 18;10(15):12189-12216. doi: 10.1021/acsami.7b12320. Epub 2017 Oct 27.

PMID:
29043778
11.

Computational design of environmental sensors for the potent opioid fentanyl.

Bick MJ, Greisen PJ, Morey KJ, Antunes MS, La D, Sankaran B, Reymond L, Johnsson K, Medford JI, Baker D.

Elife. 2017 Sep 19;6. pii: e28909. doi: 10.7554/eLife.28909.

12.

An Immunohistochemical Investigation of Renal Phospholipidosis and Toxicity in Rats.

Ma JY, Snook S, Garrovillo S, Johnson C, La D.

Int J Toxicol. 2017 Sep/Oct;36(5):386-394. doi: 10.1177/1091581817726040. Epub 2017 Aug 18.

PMID:
28820006
13.

Discovery of a biarylamide series of potent, state-dependent NaV1.7 inhibitors.

Schenkel LB, DiMauro EF, Nguyen HN, Chakka N, Du B, Foti RS, Guzman-Perez A, Jarosh M, La DS, Ligutti J, Milgram BC, Moyer BD, Peterson EA, Roberts J, Yu VL, Weiss MM.

Bioorg Med Chem Lett. 2017 Aug 15;27(16):3817-3824. doi: 10.1016/j.bmcl.2017.06.054. Epub 2017 Jun 26.

PMID:
28684121
14.

The discovery of benzoxazine sulfonamide inhibitors of NaV1.7: Tools that bridge efficacy and target engagement.

La DS, Peterson EA, Bode C, Boezio AA, Bregman H, Chu-Moyer MY, Coats J, DiMauro EF, Dineen TA, Du B, Gao H, Graceffa R, Gunaydin H, Guzman-Perez A, Fremeau R Jr, Huang X, Ilch C, Kornecook TJ, Kreiman C, Ligutti J, Jasmine Lin MH, McDermott JS, Marx I, Matson DJ, McDonough SI, Moyer BD, Nho Nguyen H, Taborn K, Yu V, Weiss MM.

Bioorg Med Chem Lett. 2017 Aug 1;27(15):3477-3485. doi: 10.1016/j.bmcl.2017.05.070. Epub 2017 Jun 1.

PMID:
28629594
15.

Computational design of trimeric influenza-neutralizing proteins targeting the hemagglutinin receptor binding site.

Strauch EM, Bernard SM, La D, Bohn AJ, Lee PS, Anderson CE, Nieusma T, Holstein CA, Garcia NK, Hooper KA, Ravichandran R, Nelson JW, Sheffler W, Bloom JD, Lee KK, Ward AB, Yager P, Fuller DH, Wilson IA, Baker D.

Nat Biotechnol. 2017 Jul;35(7):667-671. doi: 10.1038/nbt.3907. Epub 2017 Jun 12.

16.

Graphene-Supported Spinel CuFe₂O₄ Composites: Novel Adsorbents for Arsenic Removal in Aqueous Media.

La DD, Nguyen TA, Jones LA, Bhosale SV.

Sensors (Basel). 2017 Jun 5;17(6). pii: E1292. doi: 10.3390/s17061292.

17.

Nearly 400 million people are at higher risk of schistosomiasis because dams block the migration of snail-eating river prawns.

Sokolow SH, Jones IJ, Jocque M, La D, Cords O, Knight A, Lund A, Wood CL, Lafferty KD, Hoover CM, Collender PA, Remais JV, Lopez-Carr D, Fisk J, Kuris AM, De Leo GA.

Philos Trans R Soc Lond B Biol Sci. 2017 Jun 5;372(1722). pii: 20160127. doi: 10.1098/rstb.2016.0127.

18.

Correction to "Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement".

Marx IE, Dineen TA, Able J, Bode C, Bregman H, Chu-Moyer M, DiMauro EF, Du B, Foti RS, Fremeau RT Jr, Gao H, Gunaydin H, Hall BE, Huang L, Kornecook T, Kreiman CR, La DS, Ligutti J, Lin MJ, Liu D, McDermott JS, Moyer BD, Nguyen HN, Peterson EA, Roberts JT, Rose P, Wang J, Youngblood BD, Yu V, Weiss MM.

ACS Med Chem Lett. 2017 Feb 28;8(3):378. doi: 10.1021/acsmedchemlett.7b00075. eCollection 2017 Mar 9.

19.

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency, Pharmacokinetics, and Metabolic Properties to Obtain Atropisomeric Quinolinone (AM-0466) that Affords Robust in Vivo Activity.

Graceffa RF, Boezio AA, Able J, Altmann S, Berry LM, Boezio C, Butler JR, Chu-Moyer M, Cooke M, DiMauro EF, Dineen TA, Feric Bojic E, Foti RS, Fremeau RT Jr, Guzman-Perez A, Gao H, Gunaydin H, Huang H, Huang L, Ilch C, Jarosh M, Kornecook T, Kreiman CR, La DS, Ligutti J, Milgram BC, Lin MJ, Marx IE, Nguyen HN, Peterson EA, Rescourio G, Roberts J, Schenkel L, Shimanovich R, Sparling BA, Stellwagen J, Taborn K, Vaida KR, Wang J, Yeoman J, Yu V, Zhu D, Moyer BD, Weiss MM.

J Med Chem. 2017 Jul 27;60(14):5990-6017. doi: 10.1021/acs.jmedchem.6b01850. Epub 2017 Apr 20.

PMID:
28324649
20.

Efficacy and Safety of Direct Acting Antivirals for the Treatment of Mixed Cryoglobulinemia.

Emery JS, Kuczynski M, La D, Almarzooqi S, Kowgier M, Shah H, Wong D, Janssen HLA, Feld JJ.

Am J Gastroenterol. 2017 Aug;112(8):1298-1308. doi: 10.1038/ajg.2017.49. Epub 2017 Mar 14.

PMID:
28291241
21.

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics While Mitigating Metabolic Liabilities.

Weiss MM, Dineen TA, Marx IE, Altmann S, Boezio A, Bregman H, Chu-Moyer M, DiMauro EF, Feric Bojic E, Foti RS, Gao H, Graceffa R, Gunaydin H, Guzman-Perez A, Huang H, Huang L, Jarosh M, Kornecook T, Kreiman CR, Ligutti J, La DS, Lin MJ, Liu D, Moyer BD, Nguyen HN, Peterson EA, Rose PE, Taborn K, Youngblood BD, Yu V, Fremeau RT Jr.

J Med Chem. 2017 Jul 27;60(14):5969-5989. doi: 10.1021/acs.jmedchem.6b01851. Epub 2017 Apr 20.

PMID:
28287723
22.

Clinical Development of Histamine H4 Receptor Antagonists.

Thurmond RL, Venable J, Savall B, La D, Snook S, Dunford PJ, Edwards JP.

Handb Exp Pharmacol. 2017;241:301-320. doi: 10.1007/164_2016_130. Review.

PMID:
28233185
23.

Flower-like superstructures of AIE-active tetraphenylethylene through solvophobic controlled self-assembly.

Salimimarand M, La DD, Kobaisi MA, Bhosale SV.

Sci Rep. 2017 Feb 23;7:42898. doi: 10.1038/srep42898.

24.

Chiral Assembly of AIE-Active Achiral Molecules: An Odd Effect in Self-Assembly.

Anuradha, La DD, Al Kobaisi M, Gupta A, Bhosale SV.

Chemistry. 2017 Mar 17;23(16):3950-3956. doi: 10.1002/chem.201605458. Epub 2017 Feb 20.

PMID:
28217844
25.

Sulfonamides as Selective NaV1.7 Inhibitors: Optimizing Potency and Pharmacokinetics to Enable in Vivo Target Engagement.

Marx IE, Dineen TA, Able J, Bode C, Bregman H, Chu-Moyer M, DiMauro EF, Du B, Foti RS, Fremeau RT Jr, Gao H, Gunaydin H, Hall BE, Huang L, Kornecook T, Kreiman CR, La DS, Ligutti J, Lin MJ, Liu D, McDermott JS, Moyer BD, Peterson EA, Roberts JT, Rose P, Wang J, Youngblood BD, Yu V, Weiss MM.

ACS Med Chem Lett. 2016 Sep 21;7(12):1062-1067. eCollection 2016 Dec 8. Erratum in: ACS Med Chem Lett. 2017 Feb 28;8(3):378.

26.

Arginine-induced porphyrin-based self-assembled nanostructures for photocatalytic applications under simulated sunlight irradiation.

La DD, Bhosale SV, Jones LA, Bhosale SV.

Photochem Photobiol Sci. 2017 Feb 15;16(2):151-154. doi: 10.1039/c6pp00335d.

PMID:
27976777
27.
28.

Hemodynamic changes in a rat parietal cortex after endothelin-1-induced middle cerebral artery occlusion monitored by optical coherence tomography.

Liu J, Ma Y, Dou S, Wang Y, La D, Liu J, Ma Z.

J Biomed Opt. 2016 Jul 1;21(7):75014. doi: 10.1117/1.JBO.21.7.075014.

PMID:
27469083
29.

Controlled chiral supramolecular assemblies of water soluble achiral porphyrins induced by chiral counterions.

Rananaware A, La DD, Al Kobaisi M, Bhosale RS, Bhosale SV, Bhosale SV.

Chem Commun (Camb). 2016 Aug 11;52(67):10253-6. doi: 10.1039/c6cc04427a.

PMID:
27464524
30.

Effect of Amide Hydrogen Bonding Interaction on Supramolecular Self-Assembly of Naphthalene Diimide Amphiphiles with Aggregation Induced Emission.

Ghule NV, La DD, Bhosale RS, Al Kobaisi M, Raynor AM, Bhosale SV, Bhosale SV.

ChemistryOpen. 2016 Jan 11;5(2):157-63. doi: 10.1002/open.201500201. eCollection 2016 Apr.

31.

Lymphoma Remission by Interferon-Free HCV Eradication Without Chemotherapy.

Lim LY, La D, Cserti-Gazdewich CM, Shah H.

ACG Case Rep J. 2015 Oct 9;3(1):69-70. doi: 10.14309/crj.2015.104. eCollection 2015 Oct.

32.

Right handed chiral superstructures from achiral molecules: self-assembly with a twist.

Anuradha, La DD, Al Kobaisi M, Bhosale SV.

Sci Rep. 2015 Oct 23;5:15652. doi: 10.1038/srep15652.

33.

Next generation sequencing of the hepatitis C virus NS5B gene reveals potential novel S282 drug resistance mutations.

Ji H, Kozak RA, Biondi MJ, Pilon R, Vallee D, Liang BB, La D, Kim J, Van Domselaar G, Leonard L, Sandstrom P, Brooks J.

Virology. 2015 Mar;477:1-9. doi: 10.1016/j.virol.2014.12.037. Epub 2015 Jan 17.

34.

Testicular distribution and toxicity of a novel LTA4H inhibitor in rats.

Ward PD, La D.

Toxicol Appl Pharmacol. 2014 Jul 1;278(1):26-30. doi: 10.1016/j.taap.2014.04.012. Epub 2014 Apr 22.

PMID:
24769091
35.

Clinical and preclinical characterization of the histamine H(4) receptor antagonist JNJ-39758979.

Thurmond RL, Chen B, Dunford PJ, Greenspan AJ, Karlsson L, La D, Ward P, Xu XL.

J Pharmacol Exp Ther. 2014 May;349(2):176-84. doi: 10.1124/jpet.113.211714. Epub 2014 Feb 18.

PMID:
24549371
36.

Time course of renal proximal tubule injury, reversal, and related biomarker changes in rats following cisplatin administration.

McDuffie JE, Ma JY, Sablad M, Sonee M, Varacallo L, Louden C, Guy A, Vegas J, Liu X, La D, Snook S.

Int J Toxicol. 2013 Jul;32(4):251-60. doi: 10.1177/1091581813493013. Epub 2013 Jun 20.

PMID:
23788329
37.

Predicting permanent and transient protein-protein interfaces.

La D, Kong M, Hoffman W, Choi YI, Kihara D.

Proteins. 2013 May;81(5):805-18. doi: 10.1002/prot.24235. Epub 2013 Jan 15.

38.

A Potent and Orally Efficacious, Hydroxyethylamine-Based Inhibitor of β-Secretase.

Kaller MR, Harried SS, Albrecht B, Amarante P, Babu-Khan S, Bartberger MD, Brown J, Brown R, Chen K, Cheng Y, Citron M, Croghan MD, Graceffa R, Hickman D, Judd T, Kriemen C, La D, Li V, Lopez P, Luo Y, Masse C, Monenschein H, Nguyen T, Pennington LD, Miguel TS, Sickmier EA, Wahl RC, Weiss MM, Wen PH, Williamson T, Wood S, Xue M, Yang B, Zhang J, Patel V, Zhong W, Hitchcock S.

ACS Med Chem Lett. 2012 Mar 29;3(11):886-91. doi: 10.1021/ml3000148. eCollection 2012 Nov 8.

39.

Structure- and property-based design of aminooxazoline xanthenes as selective, orally efficacious, and CNS penetrable BACE inhibitors for the treatment of Alzheimer's disease.

Huang H, La DS, Cheng AC, Whittington DA, Patel VF, Chen K, Dineen TA, Epstein O, Graceffa R, Hickman D, Kiang YH, Louie S, Luo Y, Wahl RC, Wen PH, Wood S, Fremeau RT Jr.

J Med Chem. 2012 Nov 8;55(21):9156-69. doi: 10.1021/jm300598e. Epub 2012 Sep 11.

PMID:
22928914
40.

Discovery and optimization of potent and selective imidazopyridine and imidazopyridazine mTOR inhibitors.

Peterson EA, Boezio AA, Andrews PS, Boezio CM, Bush TL, Cheng AC, Choquette D, Coats JR, Colletti AE, Copeland KW, DuPont M, Graceffa R, Grubinska B, Kim JL, Lewis RT, Liu J, Mullady EL, Potashman MH, Romero K, Shaffer PL, Stanton MK, Stellwagen JC, Teffera Y, Yi S, Cai T, La DS.

Bioorg Med Chem Lett. 2012 Aug 1;22(15):4967-74. doi: 10.1016/j.bmcl.2012.06.033. Epub 2012 Jun 16.

PMID:
22765895
41.

Metformin inhibits the development and metastasis of ovarian cancer.

Wu B, Li S, Sheng L, Zhu J, Gu L, Shen H, La D, Hambly BD, Bao S, Di W.

Oncol Rep. 2012 Sep;28(3):903-8. doi: 10.3892/or.2012.1890. Epub 2012 Jun 29.

PMID:
22752027
42.

Efferent duct toxicity with secondary testicular changes in rats following administration of a novel leukotriene A₄ hydrolase inhibitor.

La DK, Creasy DM, Hess RA, Baxter E, Pereira ME, Johnson CA, Vinken P, Snook SS.

Toxicol Pathol. 2012 Jul;40(5):705-14. doi: 10.1177/0192623312441412. Epub 2012 May 2.

PMID:
22552396
43.

Design and synthesis of potent, orally efficacious hydroxyethylamine derived β-site amyloid precursor protein cleaving enzyme (BACE1) inhibitors.

Dineen TA, Weiss MM, Williamson T, Acton P, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dunn RT 2nd, Esmay J, Graceffa RF, Harried SS, Hickman D, Hitchcock SA, Horne DB, Huang H, Imbeah-Ampiah R, Judd T, Kaller MR, Kreiman CR, La DS, Li V, Lopez P, Louie S, Monenschein H, Nguyen TT, Pennington LD, San Miguel T, Sickmier EA, Vargas HM, Wahl RC, Wen PH, Whittington DA, Wood S, Xue Q, Yang BH, Patel VF, Zhong W.

J Med Chem. 2012 Nov 8;55(21):9025-44. doi: 10.1021/jm300118s. Epub 2012 Apr 18.

PMID:
22468684
44.

Design and preparation of a potent series of hydroxyethylamine containing β-secretase inhibitors that demonstrate robust reduction of central β-amyloid.

Weiss MM, Williamson T, Babu-Khan S, Bartberger MD, Brown J, Chen K, Cheng Y, Citron M, Croghan MD, Dineen TA, Esmay J, Graceffa RF, Harried SS, Hickman D, Hitchcock SA, Horne DB, Huang H, Imbeah-Ampiah R, Judd T, Kaller MR, Kreiman CR, La DS, Li V, Lopez P, Louie S, Monenschein H, Nguyen TT, Pennington LD, Rattan C, San Miguel T, Sickmier EA, Wahl RC, Wen PH, Wood S, Xue Q, Yang BH, Patel VF, Zhong W.

J Med Chem. 2012 Nov 8;55(21):9009-24. doi: 10.1021/jm300119p. Epub 2012 Apr 18.

PMID:
22468639
45.

Enrichment of variations in KIR3DL1/S1 and KIR2DL2/L3 among H1N1/09 ICU patients: an exploratory study.

La D, Czarnecki C, El-Gabalawy H, Kumar A, Meyers AF, Bastien N, Simonsen JN, Plummer FA, Luo M.

PLoS One. 2011;6(12):e29200. doi: 10.1371/journal.pone.0029200. Epub 2011 Dec 28.

46.

A novel method for protein-protein interaction site prediction using phylogenetic substitution models.

La D, Kihara D.

Proteins. 2012 Jan;80(1):126-41. doi: 10.1002/prot.23169. Epub 2011 Oct 12.

47.

MR spectroscopy for assessment of memantine treatment in mild to moderate Alzheimer dementia.

Ashford JW, Adamson M, Beale T, La D, Hernandez B, Noda A, Rosen A, O'Hara R, Fairchild JK, Spielman D, Yesavage JA.

J Alzheimers Dis. 2011;26 Suppl 3:331-6. doi: 10.3233/JAD-2011-0021.

48.

N-terminal Gly(224)-Gly(411) domain in Listeria adhesion protein interacts with host receptor Hsp60.

Jagadeesan B, Fleishman Littlejohn AE, Amalaradjou MA, Singh AK, Mishra KK, La D, Kihara D, Bhunia AK.

PLoS One. 2011;6(6):e20694. doi: 10.1371/journal.pone.0020694. Epub 2011 Jun 29.

49.

Discovery of triazine-benzimidazoles as selective inhibitors of mTOR.

Peterson EA, Andrews PS, Be X, Boezio AA, Bush TL, Cheng AC, Coats JR, Colletti AE, Copeland KW, DuPont M, Graceffa R, Grubinska B, Harmange JC, Kim JL, Mullady EL, Olivieri P, Schenkel LB, Stanton MK, Teffera Y, Whittington DA, Cai T, La DS.

Bioorg Med Chem Lett. 2011 Apr 1;21(7):2064-70. doi: 10.1016/j.bmcl.2011.02.007. Epub 2011 Feb 12.

PMID:
21376583

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