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Items: 47

1.

Dual-transmitter systems regulating arousal, attention, learning and memory.

Ma S, Hangya B, Leonard CS, Wisden W, Gundlach AL.

Neurosci Biobehav Rev. 2018 Feb;85:21-33. doi: 10.1016/j.neubiorev.2017.07.009. Epub 2017 Jul 27. Review.

PMID:
28757457
2.

Hypocretin/Orexin Peptides Alter Spike Encoding by Serotonergic Dorsal Raphe Neurons through Two Distinct Mechanisms That Increase the Late Afterhyperpolarization.

Ishibashi M, Gumenchuk I, Miyazaki K, Inoue T, Ross WN, Leonard CS.

J Neurosci. 2016 Sep 28;36(39):10097-115. doi: 10.1523/JNEUROSCI.0635-16.2016. Epub 2016 Sep 28.

3.

Orexin Receptor Activation Generates Gamma Band Input to Cholinergic and Serotonergic Arousal System Neurons and Drives an Intrinsic Ca(2+)-Dependent Resonance in LDT and PPT Cholinergic Neurons.

Ishibashi M, Gumenchuk I, Kang B, Steger C, Lynn E, Molina NE, Eisenberg LM, Leonard CS.

Front Neurol. 2015 Jun 2;6:120. doi: 10.3389/fneur.2015.00120. eCollection 2015.

4.

Reductions in invasive device use and care costs after institution of a daily safety checklist in a pediatric critical care unit.

Tarrago R, Nowak JE, Leonard CS, Payne NR.

Jt Comm J Qual Patient Saf. 2014 Jun;40(6):270-8.

PMID:
25016675
5.

Age-related changes in nicotine response of cholinergic and non-cholinergic laterodorsal tegmental neurons: implications for the heightened adolescent susceptibility to nicotine addiction.

Christensen MH, Ishibashi M, Nielsen ML, Leonard CS, Kohlmeier KA.

Neuropharmacology. 2014 Oct;85:263-83. doi: 10.1016/j.neuropharm.2014.05.010. Epub 2014 May 24.

6.

Differential actions of orexin receptors in brainstem cholinergic and monoaminergic neurons revealed by receptor knockouts: implications for orexinergic signaling in arousal and narcolepsy.

Kohlmeier KA, Tyler CJ, Kalogiannis M, Ishibashi M, Kristensen MP, Gumenchuk I, Chemelli RM, Kisanuki YY, Yanagisawa M, Leonard CS.

Front Neurosci. 2013 Dec 20;7:246. doi: 10.3389/fnins.2013.00246. eCollection 2013.

7.

Orexin/hypocretin receptor signalling cascades.

Kukkonen JP, Leonard CS.

Br J Pharmacol. 2014 Jan;171(2):314-31. doi: 10.1111/bph.12324. Review.

8.

Orexin/hypocretin receptor signalling: a functional perspective.

Leonard CS, Kukkonen JP.

Br J Pharmacol. 2014 Jan;171(2):294-313. doi: 10.1111/bph.12296.

9.

Knockouts reveal overlapping functions of M(2) and M(4) muscarinic receptors and evidence for a local glutamatergic circuit within the laterodorsal tegmental nucleus.

Kohlmeier KA, Ishibashi M, Wess J, Bickford ME, Leonard CS.

J Neurophysiol. 2012 Nov;108(10):2751-66. doi: 10.1152/jn.01120.2011. Epub 2012 Sep 5.

10.

Cholinergic modulation of narcoleptic attacks in double orexin receptor knockout mice.

Kalogiannis M, Hsu E, Willie JT, Chemelli RM, Kisanuki YY, Yanagisawa M, Leonard CS.

PLoS One. 2011 Apr 13;6(4):e18697. doi: 10.1371/journal.pone.0018697.

11.

Narcoleptic orexin receptor knockout mice express enhanced cholinergic properties in laterodorsal tegmental neurons.

Kalogiannis M, Grupke SL, Potter PE, Edwards JG, Chemelli RM, Kisanuki YY, Yanagisawa M, Leonard CS.

Eur J Neurosci. 2010 Jul;32(1):130-42. doi: 10.1111/j.1460-9568.2010.07259.x. Epub 2010 Jun 22.

12.

Nicotinic activation of laterodorsal tegmental neurons: implications for addiction to nicotine.

Ishibashi M, Leonard CS, Kohlmeier KA.

Neuropsychopharmacology. 2009 Nov;34(12):2529-47. doi: 10.1038/npp.2009.82. Epub 2009 Jul 22.

13.

Dual orexin actions on dorsal raphe and laterodorsal tegmentum neurons: noisy cation current activation and selective enhancement of Ca2+ transients mediated by L-type calcium channels.

Kohlmeier KA, Watanabe S, Tyler CJ, Burlet S, Leonard CS.

J Neurophysiol. 2008 Oct;100(4):2265-81. doi: 10.1152/jn.01388.2007. Epub 2008 Jul 30.

15.

Urotensin II acts as a modulator of mesopontine cholinergic neurons.

Clark SD, Nothacker HP, Blaha CD, Tyler CJ, Duangdao DM, Grupke SL, Helton DR, Leonard CS, Civelli O.

Brain Res. 2005 Oct 19;1059(2):139-48. Epub 2005 Sep 23.

PMID:
16183039
16.

Urotensin II modulates rapid eye movement sleep through activation of brainstem cholinergic neurons.

Huitron-Resendiz S, Kristensen MP, Sánchez-Alavez M, Clark SD, Grupke SL, Tyler C, Suzuki C, Nothacker HP, Civelli O, Criado JR, Henriksen SJ, Leonard CS, de Lecea L.

J Neurosci. 2005 Jun 8;25(23):5465-74.

17.

Specific functions of synaptically localized potassium channels in synaptic transmission at the neocortical GABAergic fast-spiking cell synapse.

Goldberg EM, Watanabe S, Chang SY, Joho RH, Huang ZJ, Leonard CS, Rudy B.

J Neurosci. 2005 May 25;25(21):5230-5.

18.
19.

Distinct narcolepsy syndromes in Orexin receptor-2 and Orexin null mice: molecular genetic dissection of Non-REM and REM sleep regulatory processes.

Willie JT, Chemelli RM, Sinton CM, Tokita S, Williams SC, Kisanuki YY, Marcus JN, Lee C, Elmquist JK, Kohlmeier KA, Leonard CS, Richardson JA, Hammer RE, Yanagisawa M.

Neuron. 2003 Jun 5;38(5):715-30.

21.

Activity-dependent nitric oxide concentration dynamics in the laterodorsal tegmental nucleus in vitro.

Leonard CS, Michaelis EK, Mitchell KM.

J Neurophysiol. 2001 Nov;86(5):2159-72.

22.

Impaired fast-spiking, suppressed cortical inhibition, and increased susceptibility to seizures in mice lacking Kv3.2 K+ channel proteins.

Lau D, Vega-Saenz de Miera EC, Contreras D, Ozaita A, Harvey M, Chow A, Noebels JL, Paylor R, Morgan JI, Leonard CS, Rudy B.

J Neurosci. 2000 Dec 15;20(24):9071-85.

23.
24.

Function of specific K(+) channels in sustained high-frequency firing of fast-spiking neocortical interneurons.

Erisir A, Lau D, Rudy B, Leonard CS.

J Neurophysiol. 1999 Nov;82(5):2476-89. Erratum in: J Neurophysiol 2000 Jul;84(1):followi.

25.
27.
28.

Spike train encoding by regular-spiking cells of the visual cortex.

Carandini M, Mechler F, Leonard CS, Movshon JA.

J Neurophysiol. 1996 Nov;76(5):3425-41.

PMID:
8930283
29.
30.

NMDA-receptor-mediated synaptic currents in guinea pig laterodorsal tegmental neurons in vitro.

Sanchez R, Leonard CS.

J Neurophysiol. 1996 Aug;76(2):1101-11.

PMID:
8871223
32.
33.
35.

Representations of ocular rotations in the cerebellar flocculus of the rabbit.

Simpson JI, Van der Steen J, Tan J, Graf W, Leonard CS.

Prog Brain Res. 1989;80:213-23; discussion 211-2.

PMID:
2634272
36.
37.
38.

The accessory optic system of rabbit. II. Spatial organization of direction selectivity.

Simpson JI, Leonard CS, Soodak RE.

J Neurophysiol. 1988 Dec;60(6):2055-72.

PMID:
3236061
39.

The accessory optic system. Analyzer of self-motion.

Simpson JI, Leonard CS, Soodak RE.

Ann N Y Acad Sci. 1988;545:170-9. No abstract available.

PMID:
3239883
40.

Intraterminal injection of synapsin I or calcium/calmodulin-dependent protein kinase II alters neurotransmitter release at the squid giant synapse.

Llinás R, McGuinness TL, Leonard CS, Sugimori M, Greengard P.

Proc Natl Acad Sci U S A. 1985 May;82(9):3035-9.

41.

Plasma amino acids in full-term infants.

Berry HK, Leonard CS.

Am J Clin Nutr. 1966 Aug;19(2):99-104. No abstract available.

PMID:
5916039
42.

An estimation of the activity of analgetic materials.

BONNYCASTLE DD, LEONARD CS.

J Pharmacol Exp Ther. 1950 Oct;100(2):141-5. No abstract available.

PMID:
14784950
43.

Effects of mercury salts on the composition of the gastric juice.

DREYER NB, LEONARD CS.

Arch Int Pharmacodyn Ther. 1949 Jan 1;78(1):86-92. No abstract available.

PMID:
18124422
44.

Influence of oxophenarsine on hypoglycemic action of insulin.

LEONARD CS.

Proc Soc Exp Biol Med. 1948 Jan;67(1):89-92. No abstract available.

PMID:
18902303
45.

The Immunizing Effect in the Action of Trypanocidal Agents.

Leonard CS.

Science. 1946 Dec 6;104(2710):556. No abstract available.

PMID:
17840545
46.

Lack of Influence of Thiosulfate and Metabisulfite on the Antibiotic Activity of Penicillin.

Leonard CS.

Science. 1946 Nov 29;104(2709):501-2. No abstract available.

PMID:
17743262
47.

The problem of the role of sulfhydryl enzymes in the mechanism of the action of certain chemotherapeutic agents.

LEONARD CS.

Bull Am Pharm Assoc. 1946 Jul-Aug;14(7-8):139-49. No abstract available.

PMID:
20285805

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