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Items: 30


Hematopoietic stem and progenitor cell proliferation and differentiation requires the trithorax protein Ash2l.

Lüscher-Firzlaff J, Chatain N, Kuo CC, Braunschweig T, Bochyńska A, Ullius A, Denecke B, Costa IG, Koschmieder S, Lüscher B.

Sci Rep. 2019 Jun 4;9(1):8262. doi: 10.1038/s41598-019-44720-3.


Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin.

Bochyńska A, Lüscher-Firzlaff J, Lüscher B.

Cells. 2018 Mar 2;7(3). pii: E17. doi: 10.3390/cells7030017. Review.


Endotoxin tolerance in mast cells, its consequences for IgE-mediated signalling, and the effects of BCL3 deficiency.

Poplutz M, Levikova M, Lüscher-Firzlaff J, Lesina M, Algül H, Lüscher B, Huber M.

Sci Rep. 2017 Jul 3;7(1):4534. doi: 10.1038/s41598-017-04890-4.


ING5 is phosphorylated by CDK2 and controls cell proliferation independently of p53.

Linzen U, Lilischkis R, Pandithage R, Schilling B, Ullius A, Lüscher-Firzlaff J, Kremmer E, Lüscher B, Vervoorts J.

PLoS One. 2015 Apr 10;10(4):e0123736. doi: 10.1371/journal.pone.0123736. eCollection 2015.


The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification.

Ullius A, Lüscher-Firzlaff J, Costa IG, Walsemann G, Forst AH, Gusmao EG, Kapelle K, Kleine H, Kremmer E, Vervoorts J, Lüscher B.

Nucleic Acids Res. 2014 Jun;42(11):6901-20. doi: 10.1093/nar/gku312. Epub 2014 Apr 29.


Dynamic subcellular localization of the mono-ADP-ribosyltransferase ARTD10 and interaction with the ubiquitin receptor p62.

Kleine H, Herrmann A, Lamark T, Forst AH, Verheugd P, Lüscher-Firzlaff J, Lippok B, Feijs KL, Herzog N, Kremmer E, Johansen T, Müller-Newen G, Lüscher B.

Cell Commun Signal. 2012 Sep 20;10(1):28. doi: 10.1186/1478-811X-10-28.


The chemopreventive agent ursodeoxycholic acid inhibits proliferation of colon carcinoma cells by suppressing c-Myc expression.

Peiró-Jordán R, Krishna-Subramanian S, Hanski ML, Lüscher-Firzlaff J, Zeitz M, Hanski C.

Eur J Cancer Prev. 2012 Sep;21(5):413-22. doi: 10.1097/CEJ.0b013e32834ef16f.


IL-31 regulates differentiation and filaggrin expression in human organotypic skin models.

Cornelissen C, Marquardt Y, Czaja K, Wenzel J, Frank J, Lüscher-Firzlaff J, Lüscher B, Baron JM.

J Allergy Clin Immunol. 2012 Feb;129(2):426-33, 433.e1-8. doi: 10.1016/j.jaci.2011.10.042. Epub 2011 Dec 15.


Signaling by IL-31 and functional consequences.

Cornelissen C, Lüscher-Firzlaff J, Baron JM, Lüscher B.

Eur J Cell Biol. 2012 Jun-Jul;91(6-7):552-66. doi: 10.1016/j.ejcb.2011.07.006. Epub 2011 Oct 5. Review.


Ultraviolet B radiation and reactive oxygen species modulate interleukin-31 expression in T lymphocytes, monocytes and dendritic cells.

Cornelissen C, Brans R, Czaja K, Skazik C, Marquardt Y, Zwadlo-Klarwasser G, Kim A, Bickers DR, Lüscher-Firzlaff J, Lüscher B, Baron JM.

Br J Dermatol. 2011 Nov;165(5):966-75. doi: 10.1111/j.1365-2133.2011.10487.x. Epub 2011 Oct 17.


The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility.

Pandithage R, Lilischkis R, Harting K, Wolf A, Jedamzik B, Lüscher-Firzlaff J, Vervoorts J, Lasonder E, Kremmer E, Knöll B, Lüscher B.

J Cell Biol. 2008 Mar 10;180(5):915-29. doi: 10.1083/jcb.200707126.


Tight correlation between expression of the Forkhead transcription factor FOXM1 and HER2 in human breast cancer.

Bektas N, Haaf At, Veeck J, Wild PJ, Lüscher-Firzlaff J, Hartmann A, Knüchel R, Dahl E.

BMC Cancer. 2008 Feb 6;8:42. doi: 10.1186/1471-2407-8-42.


The human trithorax protein hASH2 functions as an oncoprotein.

Lüscher-Firzlaff J, Gawlista I, Vervoorts J, Kapelle K, Braunschweig T, Walsemann G, Rodgarkia-Schamberger C, Schuchlautz H, Dreschers S, Kremmer E, Lilischkis R, Cerni C, Wellmann A, Lüscher B.

Cancer Res. 2008 Feb 1;68(3):749-58. doi: 10.1158/0008-5472.CAN-07-3158.


Regulation of the MAD1 promoter by G-CSF.

Jiang K, Hein N, Eckert K, Lüscher-Firzlaff J, Lüscher B.

Nucleic Acids Res. 2008 Mar;36(5):1517-31. doi: 10.1093/nar/gkn002. Epub 2008 Jan 18.


Inhibition of apoptosis by MAD1 is mediated by repression of the PTEN tumor suppressor gene.

Rottmann S, Speckgens S, Lüscher-Firzlaff J, Lüscher B.

FASEB J. 2008 Apr;22(4):1124-34. Epub 2007 Nov 12.


The ins and outs of MYC regulation by posttranslational mechanisms.

Vervoorts J, Lüscher-Firzlaff J, Lüscher B.

J Biol Chem. 2006 Nov 17;281(46):34725-9. Epub 2006 Sep 20. Review.


CD73/ecto-5'-nucleotidase protects against vascular inflammation and neointima formation.

Zernecke A, Bidzhekov K, Ozüyaman B, Fraemohs L, Liehn EA, Lüscher-Firzlaff JM, Lüscher B, Schrader J, Weber C.

Circulation. 2006 May 2;113(17):2120-7. Epub 2006 Apr 24.


Regulation of the transcription factor FOXM1c by Cyclin E/CDK2.

Lüscher-Firzlaff JM, Lilischkis R, Lüscher B.

FEBS Lett. 2006 Mar 20;580(7):1716-22. Epub 2006 Feb 20.


Y-box protein 1 mediates PDGF-B effects in mesangioproliferative glomerular disease.

van Roeyen CR, Eitner F, Martinkus S, Thieltges SR, Ostendorf T, Bokemeyer D, Lüscher B, Lüscher-Firzlaff JM, Floege J, Mertens PR.

J Am Soc Nephrol. 2005 Oct;16(10):2985-96. Epub 2005 Aug 10.


Overlap of the gene encoding the novel poly(ADP-ribose) polymerase Parp10 with the plectin 1 gene and common use of exon sequences.

Lesniewicz K, Lüscher-Firzlaff J, Poreba E, Fuchs P, Walsemann G, Wiche G, Lüscher B.

Genomics. 2005 Jul;86(1):38-46.


Mad1 function in cell proliferation and transcriptional repression is antagonized by cyclin E/CDK2.

Rottmann S, Menkel AR, Bouchard C, Mertsching J, Loidl P, Kremmer E, Eilers M, Lüscher-Firzlaff J, Lilischkis R, Lüscher B.

J Biol Chem. 2005 Apr 22;280(16):15489-92. Epub 2005 Feb 18.


PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation.

Yu M, Schreek S, Cerni C, Schamberger C, Lesniewicz K, Poreba E, Vervoorts J, Walsemann G, Grötzinger J, Kremmer E, Mehraein Y, Mertsching J, Kraft R, Austen M, Lüscher-Firzlaff J, Lüscher B.

Oncogene. 2005 Mar 17;24(12):1982-93.


Stimulation of c-MYC transcriptional activity and acetylation by recruitment of the cofactor CBP.

Vervoorts J, Lüscher-Firzlaff JM, Rottmann S, Lilischkis R, Walsemann G, Dohmann K, Austen M, Lüscher B.

EMBO Rep. 2003 May;4(5):484-90.


Interaction of the fork head domain transcription factor MPP2 with the human papilloma virus 16 E7 protein: enhancement of transformation and transactivation.

Lüscher-Firzlaff JM, Westendorf JM, Zwicker J, Burkhardt H, Henriksson M, Müller R, Pirollet F, Lüscher B.

Oncogene. 1999 Oct 7;18(41):5620-30.


Regulation of cell growth by the Myc-Max-Mad network: role of Mad proteins and YY1.

Austen M, Cerni C, Henriksson M, Hilfenhaus S, Lüscher-Firzlaff JM, Menkel A, Seelos C, Sommer A, Lüscher B.

Curr Top Microbiol Immunol. 1997;224:123-30. Review. No abstract available.


Casein kinase II phosphorylation site mutations in c-Myb affect DNA binding and transcriptional cooperativity with NF-M.

Oelgeschläger M, Krieg J, Lüscher-Firzlaff JM, Lüscher B.

Mol Cell Biol. 1995 Nov;15(11):5966-74.


Regulation of transcription factors c-Myc, Max, and c-Myb by casein kinase II.

Bousset K, Oelgeschläger MH, Henriksson M, Schreek S, Burkhardt H, Litchfield DW, Lüscher-Firzlaff JM, Lüscher B.

Cell Mol Biol Res. 1994;40(5-6):501-11.


Identification of casein kinase II phosphorylation sites in Max: effects on DNA-binding kinetics of Max homo- and Myc/Max heterodimers.

Bousset K, Henriksson M, Lüscher-Firzlaff JM, Litchfield DW, Lüscher B.

Oncogene. 1993 Dec;8(12):3211-20.


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