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Effects of Switching to a Heat-Not-Burn Tobacco Product on Biologically Relevant Biomarkers to Assess a Candidate Modified Risk Tobacco Product: A Randomized Trial.

Lüdicke F, Ansari SM, Lama N, Blanc N, Bosilkovska M, Donelli A, Picavet P, Baker G, Haziza C, Peitsch M, Weitkunat R.

Cancer Epidemiol Biomarkers Prev. 2019 Nov;28(11):1934-1943. doi: 10.1158/1055-9965.EPI-18-0915. Epub 2019 Jul 3.


Biological and Functional Changes in Healthy Adult Smokers Who Are Continuously Abstinent From Smoking for One Year: Protocol for a Prospective, Observational, Multicenter Cohort Study.

Tran CT, Felber Medlin L, Lama N, Taranu B, Ng W, Haziza C, Picavet P, Baker G, Lüdicke F.

JMIR Res Protoc. 2019 Jun 7;8(6):e12138. doi: 10.2196/12138.


Favorable Changes in Biomarkers of Potential Harm to Reduce the Adverse Health Effects of Smoking in Smokers Switching to the Menthol Tobacco Heating System 2.2 for Three Months (Part 2).

Haziza C, de La Bourdonnaye G, Donelli A, Skiada D, Poux V, Weitkunat R, Baker G, Picavet P, Lüdicke F.

Nicotine Tob Res. 2019 May 24. pii: ntz084. doi: 10.1093/ntr/ntz084. [Epub ahead of print]


Reduction In Exposure To Selected Harmful And Potentially Harmful Constituents Approaching Those Observed Upon Smoking Abstinence In Smokers Switching To The Menthol Tobacco Heating System 2.2 For Three Months (Part 1).

Haziza C, de La Bourdonnaye G, Donelli A, Poux V, Skiada D, Weitkunat R, Baker G, Picavet P, Lüdicke F.

Nicotine Tob Res. 2019 Feb 5. doi: 10.1093/ntr/ntz013. [Epub ahead of print]


Influence of smoking on levels of urinary 8-iso Prostaglandin F2α.

van der Plas A, Pouly S, de La Bourdonnaye G, Baker G, Lüdicke F.

Toxicol Rep. 2018 Nov 20;6:18-25. doi: 10.1016/j.toxrep.2018.11.011. eCollection 2019.


Development and validation of a new instrument to measure perceived risks associated with the use of tobacco and nicotine-containing products.

Cano S, Chrea C, Salzberger T, Alfieri T, Emilien G, Mainy N, Ramazzotti A, Lüdicke F, Weitkunat R.

Health Qual Life Outcomes. 2018 Sep 21;16(1):192. doi: 10.1186/s12955-018-0997-5.


Evaluation of Biological and Functional Changes in Healthy Smokers Switching to the Tobacco Heating System 2.2 Versus Continued Tobacco Smoking: Protocol for a Randomized, Controlled, Multicenter Study.

Ansari SM, Lama N, Blanc N, Bosilkovska M, Donelli A, Picavet P, Baker G, Haziza C, Lüdicke F.

JMIR Res Protoc. 2018 Aug 24;7(8):e11294. doi: 10.2196/11294.


Modeling the impact of changes in tobacco use on individual disease risks.

Djurdjevic S, Sponsiello-Wang Z, Lee PN, Fry JS, Weitkunat R, Lüdicke F, Baker G.

Regul Toxicol Pharmacol. 2018 Aug;97:88-97. doi: 10.1016/j.yrtph.2018.06.001. Epub 2018 Jun 9.


Influence of smoking and smoking cessation on levels of urinary 11-dehydro thromboxane B2.

van der Plas A, Pouly S, de La Bourdonnaye G, Ng WT, Baker G, Lüdicke F.

Toxicol Rep. 2018 Apr 19;5:561-567. doi: 10.1016/j.toxrep.2018.04.005. eCollection 2018. Review.


Modeling the Population Health Impact of Introducing a Modified Risk Tobacco Product into the U.S. Market.

Djurdjevic S, Lee PN, Weitkunat R, Sponsiello-Wang Z, Lüdicke F, Baker G.

Healthcare (Basel). 2018 May 16;6(2). pii: E47. doi: 10.3390/healthcare6020047.


Review of biomarkers to assess the effects of switching from cigarettes to modified risk tobacco products.

Peck MJ, Sanders EB, Scherer G, Lüdicke F, Weitkunat R.

Biomarkers. 2018 Jan 9:1-32. doi: 10.1080/1354750X.2017.1419284. [Epub ahead of print]


Quantifying the risk-reduction potential of new Modified Risk Tobacco Products.

Martin F, Vuillaume G, Baker G, Sponsiello-Wang Z, Ricci PF, Lüdicke F, Weitkunat R.

Regul Toxicol Pharmacol. 2018 Feb;92:358-369. doi: 10.1016/j.yrtph.2017.12.011. Epub 2017 Dec 16.


Nicotine pharmacokinetic profiles of the Tobacco Heating System 2.2, cigarettes and nicotine gum in Japanese smokers.

Brossard P, Weitkunat R, Poux V, Lama N, Haziza C, Picavet P, Baker G, Lüdicke F.

Regul Toxicol Pharmacol. 2017 Oct;89:193-199. doi: 10.1016/j.yrtph.2017.07.032. Epub 2017 Jul 29.


Evaluation of Nicotine Pharmacokinetics and Subjective Effects following Use of a Novel Nicotine Delivery System.

Teichert A, Brossard P, Felber Medlin L, Sandalic L, Franzon M, Wynne C, Laugesen M, Lüdicke F.

Nicotine Tob Res. 2018 Mar 6;20(4):458-465. doi: 10.1093/ntr/ntx093.


Nicotine Population Pharmacokinetics in Healthy Adult Smokers: A Retrospective Analysis.

Marchand M, Brossard P, Merdjan H, Lama N, Weitkunat R, Lüdicke F.

Eur J Drug Metab Pharmacokinet. 2017 Dec;42(6):943-954. doi: 10.1007/s13318-017-0405-2.


Biomarker of exposure level data set in smokers switching from conventional cigarettes to Tobacco Heating System 2.2, continuing smoking or abstaining from smoking for 5 days.

Haziza C, de La Bourdonnaye G, Skiada D, Ancerewicz J, Baker G, Picavet P, Lüdicke F.

Data Brief. 2016 Nov 18;10:283-293. eCollection 2017 Feb.


Evaluation of the Tobacco Heating System 2.2. Part 8: 5-Day randomized reduced exposure clinical study in Poland.

Haziza C, de La Bourdonnaye G, Skiada D, Ancerewicz J, Baker G, Picavet P, Lüdicke F.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S139-S150. doi: 10.1016/j.yrtph.2016.11.003. Epub 2016 Nov 3.


Assessment of the reduction in levels of exposure to harmful and potentially harmful constituents in Japanese subjects using a novel tobacco heating system compared with conventional cigarettes and smoking abstinence: A randomized controlled study in confinement.

Haziza C, de La Bourdonnaye G, Merlet S, Benzimra M, Ancerewicz J, Donelli A, Baker G, Picavet P, Lüdicke F.

Regul Toxicol Pharmacol. 2016 Nov;81:489-499. doi: 10.1016/j.yrtph.2016.09.014. Epub 2016 Sep 29.


Reduced Exposure to Harmful and Potentially Harmful Smoke Constituents With the Tobacco Heating System 2.1.

Lüdicke F, Baker G, Magnette J, Picavet P, Weitkunat R.

Nicotine Tob Res. 2017 Feb;19(2):168-175. doi: 10.1093/ntr/ntw164. Epub 2016 Jul 1.


Evaluation of the Tobacco Heating System 2.2. Part 1: Description of the system and the scientific assessment program.

Smith MR, Clark B, Lüdicke F, Schaller JP, Vanscheeuwijck P, Hoeng J, Peitsch MC.

Regul Toxicol Pharmacol. 2016 Nov 30;81 Suppl 2:S17-S26. doi: 10.1016/j.yrtph.2016.07.006. Epub 2016 Jul 19. Review.


Evaluation of Biomarkers of Exposure in Smokers Switching to a Carbon-Heated Tobacco Product: A Controlled, Randomized, Open-Label 5-Day Exposure Study.

Lüdicke F, Haziza C, Weitkunat R, Magnette J.

Nicotine Tob Res. 2016 Jul;18(7):1606-13. doi: 10.1093/ntr/ntw022. Epub 2016 Jan 27.


A Japanese cross-sectional multicentre study of biomarkers associated with cardiovascular disease in smokers and non-smokers.

Lüdicke F, Magnette J, Baker G, Weitkunat R.

Biomarkers. 2015;20(6-7):411-21. doi: 10.3109/1354750X.2015.1096303.


Comparison of the Pharmacokinetics of Nicotine Following Single and Ad Libitum Use of a Tobacco Heating System or Combustible Cigarettes.

Picavet P, Haziza C, Lama N, Weitkunat R, Lüdicke F.

Nicotine Tob Res. 2016 May;18(5):557-63. doi: 10.1093/ntr/ntv220. Epub 2015 Oct 5.


A novel approach to assess the population health impact of introducing a Modified Risk Tobacco Product.

Weitkunat R, Lee PN, Baker G, Sponsiello-Wang Z, González-Zuloeta Ladd AM, Lüdicke F.

Regul Toxicol Pharmacol. 2015 Jun;72(1):87-93. doi: 10.1016/j.yrtph.2015.03.011. Epub 2015 Mar 27.


Population pharmacokinetic modelling of filgrastim in healthy adults following intravenous and subcutaneous administrations.

Wiczling P, Lowe P, Pigeolet E, Lüdicke F, Balser S, Krzyzanski W.

Clin Pharmacokinet. 2009;48(12):817-26. doi: 10.2165/11318090-000000000-00000.


[Historical cohort study of delivery in women of forty years of age and older].

Tebeu PM, Kouam L, Nghonguia MF, Obama MT, Major AL, Ludicke F, Ngassa P, Wamba TM, Moyo JK, Doh AS.

Rev Med Liege. 2007 Jul-Aug;62(7-8):509-14. French.


[Outcome of delivery at extreme ages of reproductive life].

Tebeu PM, Major AL, Ludicke F, Obama MT, Kouam L, Doh AS.

Rev Med Liege. 2004 Jul-Aug;59(7-8):455-9. French.


Time-dependent hexaminolaevulinate induced protoporphyrin IX distribution after topical application in patients with cervical intraepithelial neoplasia: A fluorescence microscopy study.

Andrejevic-Blant S, Major A, Lüdicke F, Ballini JP, Wagnières G, van den Bergh H, Pelte MF.

Lasers Surg Med. 2004;35(4):276-83.


Imaginary pregnancy 10 years after abortion and sterilization in a menopausal woman: a case report.

Bianchi-Demicheli F, Lüdicke F, Chardonnens D.

Maturitas. 2004 Aug 20;48(4):479-81. No abstract available.


Positive peritoneal cytology in early-stage endometrial cancer does not influence prognosis.

Tebeu PM, Popowski Y, Verkooijen HM, Bouchardy C, Ludicke F, Usel M, Major AL.

Br J Cancer. 2004 Aug 16;91(4):720-4.


Abstracts from the 8th Annual Meeting of the Scientific Association of Swiss Radiation Oncology (SASRO).

Allal AS, Ares C, Dulguerov P, Tschanz E, Verdan C, Mhawech P, Riesterer O, Honer M, Vuong V, Jochum W, Zingg D, Bodis S, Ametamey S, Pruschy M, Inteeworn N, Ohlerth S, Höpfl G, Roos M, Wergin M, Rohrer Bley C, Gassmann M, Kaser-Hotz B, Berthou S, Aebersold DM, Ganapathipillai S, Streit B, Stalder D, Gruber G, Greiner RH, Zimmer Y, Lutters G, Krek W, Tenzer A, Hofstetter B, Bonny C, Azria A, Larbouret C, Cunat S, Ozsahin M, Zouhair A, Gourgou S, Martineau P, Evans DB, Romieu G, Pujol P, Pèlegrin A, Heuberger J, Kestenholz P, Taverna Ch, Lardinois D, Jörger M, Schneiter D, Jerman M, Weder W, Stahel R, Bodis S, Vees H, Mach N, Hügli A, Balmer Majno S, Beer KT, Friedrich EE, Ciernik IF, Stanek N, Taverna C, Greiner R, Mahler F, Landmann Ch, Studer G, Bernier J, Gallino A, Juelke PD, Hafner HP, Jamshidi P, Erne P, Resink TJ, Thum P, Notter M, Bargetzi M, Suleiman M, Luthi JC, Bieri S, Curschmann J, Pajic B, Kranzbühler H, Lippold B, Ueltschi G, Bonetti M, Nasi ML, Price KN, Castiglione-Gertsch M, Rudenstam CM, Holmberg SB, Lindtner J, Gol-Ouh R, Collins J, Crivellari D, Carbone A, Thürlimann B, Simoncini E, Fey MF, Gelber RD, Coates AS, Goldhirsch A, Jeanneret Sozzi W, Kramar A, Mirimanoff RO, Azria D, Taussky D, Becker M, Kranzbuehler H, Weitzel M, Bortoluzzi L, Behrensmeier F, Isaak B, Pasche P, Luthi F, Weber DC, Lomax AJ, Rutz HP, Pedroni ES, Verwey J, Goitein G, Timmermann B, Lomax A, Bolsi A, Weber D, Bentzen SM, Khalil AA, Saunders MI, Horiot JC, Van den Bogaert W, Cummings BJ, Dische S, Slosman DO, Kebdani T, Allaoua M, Stadelmann O, Stupp R, Pica A, Dubois JB, Oehler C, Ulmer U, Lütolf UM, Huser M, Burger C, Szekely G, Davis JB, Gervaz P, Gertsch P, Morel P, Roth AD, Zenklusen H, Schott A, Curti G, Schefer H, Kolotas C, Thalmann G, Vetterli D, Kemmerling L, Mini R, Rouzaud M, Nouet P, Mollà M, Escudé L, Miralbell R, Beer K, von Briel C, Jichlinski P, Guillou L, Fogliata A, Nicolini G, Cozzi L, Hafner HP, Hueber P, Szczerba D, Born EJ, Dipasquale G, Jargy C, Munier F, Balmer A, Do HP, Pasche G, Wang H, Moeckli R, Boehringer T, Coray A, Lin S, Pedroni E, Rutz H, Baumert BG, Norton IA, Schoenmaker E, Krayenbühl J, Bründler MA, Allemann K, Laluhovà D, Collen T, Coucke P, Ries G, Rufibach K, Huguenin P, Abdou M, Girardet C, Vees HJ, Bigler R, Özsoy O, Bouville S, Corminboeuf F, Betz M, Matzinger O, Tebeu P, Popowski Y, Verkooijen H, Bouchardy C, Ludicke F, Usel M, Major A, Merçay A, Pache G, Bulling S, Bressan S, Valley JF, Motta M, Presilla S, Richetti A, Franzetti A, Pesce G.

Strahlenther Onkol. 2004 Jun;180 Suppl 1:89-108. doi: 10.1007/BF03356735. No abstract available.


Impact of peritoneal cytology on survival of endometrial cancer patients treated with surgery and radiotherapy.

Tebeu PM, Popowski GY, Verkooijen HM, Casals J, Lüdicke F, Zeciri G, Usel M, Bouchardy C, Major AL.

Br J Cancer. 2003 Dec 1;89(11):2023-6.


Women's knowledge and opinions of emergency contraception.

Nguyen L, Bianchi-Demicheli F, Lüdicke F.

Int J Gynaecol Obstet. 2003 Aug;82(2):229-30. No abstract available.


High efficacy of photodynamic therapy on rat endometrium after systemic administration of benzoporphyrin derivative monoacid ring A.

Mhawech P, Renaud A, Sene C, Lüdicke F, Herrmann F, Szalay-Quinodoz I, van den Bergh H, Major AL.

Hum Reprod. 2003 Aug;18(8):1707-11.


Photodynamic diagnosis of ovarian cancer using hexaminolaevulinate: a preclinical study.

Lüdicke F, Gabrecht T, Lange N, Wagnières G, Van Den Bergh H, Berclaz L, Major AL.

Br J Cancer. 2003 Jun 2;88(11):1780-4.


[Premenstrual dysphoric disorder: approach and treatment].

Bianchi-Demicheli F, Lüdicke F, Campana A.

Gynecol Obstet Fertil. 2003 Jan;31(1):49-54. Review. French.


Contraceptive practice before and after termination of pregnancy: a prospective study.

Bianchi-Demicheli F, Perrin E, Bianchi PG, Dumont P, Lüdicke F, Campana A.

Contraception. 2003 Feb;67(2):107-13.


Premenstrual dysphoric disorder: current status of treatment.

Bianchi-Demicheli F, Lüdicke F, Lucas H, Chardonnens D.

Swiss Med Wkly. 2002 Nov 2;132(39-40):574-8. Review.


Low dose mifepristone and two regimens of levonorgestrel for emergency contraception: a WHO multicentre randomised trial.

von Hertzen H, Piaggio G, Ding J, Chen J, Song S, Bártfai G, Ng E, Gemzell-Danielsson K, Oyunbileg A, Wu S, Cheng W, Lüdicke F, Pretnar-Darovec A, Kirkman R, Mittal S, Khomassuridze A, Apter D, Peregoudov A; WHO Research Group on Post-ovulatory Methods of Fertility Regulation.

Lancet. 2002 Dec 7;360(9348):1803-10.


Intraperitoneal photodynamic therapy in the Fischer 344 rat using 5-aminolevulinic acid and violet laser light: a toxicity study.

Major AL, Rose GS, Svaasand LO, Lüdicke F, Campana A, van Gemert MJ.

J Photochem Photobiol B. 2002 Mar;66(2):107-14.


Feasibility study to detect ovarian cancer micrometastases by fluorescence photodetection.

Major AL, Lüdicke F, Campana A.

Lasers Med Sci. 2002;17(1):2-5. No abstract available. Erratum in: Lasers Med Sci 2002;17(2):69. Campand A [corrected to Campana A].


An exploratory pilot study of acupuncture on the quality of life and reproductive hormone secretion in menopausal women.

Dong H, Lüdicke F, Comte I, Campana A, Graff P, Bischof P.

J Altern Complement Med. 2001 Dec;7(6):651-8.


Termination of pregnancy and women's sexuality.

Bianchi-Demicheli F, Perrin E, Lüdicke F, Bianchi PG, Chatton D, Campana A.

Gynecol Obstet Invest. 2002;53(1):48-53.


High- and intermediate-risk human papillomavirus infection in sexually active adolescent females.

Lüdicke F, Stalberg A, Vassilakos P, Major AL, Campana A.

J Pediatr Adolesc Gynecol. 2001 Nov;14(4):171-4.


Dose finding in a low-dose 21-day combined oral contraceptive containing gestodene.

Lüdicke F, Sullivan H, Spona J, Elstein M.

Contraception. 2001 Oct;64(4):243-8.


Contraception and sexuality after termination of pregnancy: a comparison between Lugano and Geneva.

Bianchi-Demicheli F, Perrin E, Lüdicke F, Campana A.

Swiss Med Wkly. 2001 Sep 8;131(35-36):515-20.


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