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Discordant molecular subtype classification in the basal-squamous subtype of bladder tumors and matched lymph-node metastases.

Sjödahl G, Eriksson P, Lövgren K, Marzouka NA, Bernardo C, Nordentoft I, Dyrskjøt L, Liedberg F, Höglund M.

Mod Pathol. 2018 Jul 2. doi: 10.1038/s41379-018-0096-5. [Epub ahead of print]


Acute Haemarthrosis in the Haemophilia A Rat Generates a Local and Systemic Proinflammatory Response.

Lövgren KM, Christensen KR, Majewski W, Østrup O, Skov S, Wiinberg B.

Thromb Haemost. 2017 Nov;117(11):2092-2104. doi: 10.1160/TH17-03-0149. Epub 2017 Nov 30.


Non-genetic risk factors in haemophilia A inhibitor management - the danger theory and the use of animal models.

Lövgren KM, Søndergaard H, Skov S, Wiinberg B.

Haemophilia. 2016 Sep;22(5):657-66. doi: 10.1111/hae.13075. Epub 2016 Aug 26. Review.


Joint bleeds increase the inhibitor response to human factor VIII in a rat model of severe haemophilia A.

Lövgren KM, Søndergaard H, Skov S, Wiinberg B.

Haemophilia. 2016 Sep;22(5):772-9. doi: 10.1111/hae.13014. Epub 2016 Jul 21.


Prior Adjuvant Tamoxifen Treatment in Breast Cancer Is Linked to Increased AIB1 and HER2 Expression in Metachronous Contralateral Breast Cancer.

Alkner S, Bendahl PO, Ehinger A, Lövgren K, Rydén L, Fernö M.

PLoS One. 2016 Mar 9;11(3):e0150977. doi: 10.1371/journal.pone.0150977. eCollection 2016.


Antibody response to recombinant human coagulation factor VIII in a new rat model of severe hemophilia A.

Lövgren KM, Søndergaard H, Skov S, Weldingh KN, Tranholm M, Wiinberg B.

J Thromb Haemost. 2016 Apr;14(4):747-56. doi: 10.1111/jth.13259. Epub 2016 Mar 8.


Comfortable and leisurely: Old women on style and dress.

Lövgren K.

J Women Aging. 2016;28(5):372-85. doi: 10.1080/08952841.2015.1018029. Epub 2015 Dec 29.


Characteristics and geographic distribution of HIV-positive women diagnosed with cervical cancer in Dar es Salaam, Tanzania.

Lovgren K, Soliman AS, Ngoma T, Kahesa C, Meza J.

Int J STD AIDS. 2016 Oct;27(12):1049-1056. Epub 2015 Oct 12.


Contrasting breast cancer molecular subtypes across serial tumor progression stages: biological and prognostic implications.

Kimbung S, Kovács A, Danielsson A, Bendahl PO, Lövgren K, Frostvik Stolt M, Tobin NP, Lindström L, Bergh J, Einbeigi Z, Fernö M, Hatschek T, Hedenfalk I.

Oncotarget. 2015 Oct 20;6(32):33306-18. doi: 10.18632/oncotarget.5089.


A Molecular Pathologic Framework for Risk Stratification of Stage T1 Urothelial Carcinoma.

Patschan O, Sjödahl G, Chebil G, Lövgren K, Lauss M, Gudjonsson S, Kollberg P, Eriksson P, Aine M, Månsson W, Fernö M, Liedberg F, Höglund M.

Eur Urol. 2015 Nov;68(5):824-32; discussion 835-6. doi: 10.1016/j.eururo.2015.02.021. Epub 2015 Mar 11.


Infiltration of CD3⁺ and CD68⁺ cells in bladder cancer is subtype specific and affects the outcome of patients with muscle-invasive tumors.

Sjödahl G, Lövgren K, Lauss M, Chebil G, Patschan O, Gudjonsson S, Månsson W, Fernö M, Leandersson K, Lindgren D, Liedberg F, Höglund M.

Urol Oncol. 2014 Aug;32(6):791-7. doi: 10.1016/j.urolonc.2014.02.007. Epub 2014 Apr 29.


Sensitive methods for evaluation of antibodies for host cell protein analysis and screening of impurities in a vaccine process.

Lundström CS, Mattsson A, Lövgren K, Eriksson Å, Sundberg ÅL, Lundgren M, Nilsson CE.

Vaccine. 2014 May 19;32(24):2911-5. doi: 10.1016/j.vaccine.2014.02.032. Epub 2014 Mar 11.


Immunohistochemical assessment of Ki67 with antibodies SP6 and MIB1 in primary breast cancer: a comparison of prognostic value and reproducibility.

Ekholm M, Beglerbegovic S, Grabau D, Lövgren K, Malmström P, Hartman L, Fernö M.

Histopathology. 2014 Aug;65(2):252-60. doi: 10.1111/his.12392. Epub 2014 May 16.


The prognostic value of mitotic activity index (MAI), phosphohistone H3 (PPH3), cyclin B1, cyclin A, and Ki67, alone and in combinations, in node-negative premenopausal breast cancer.

Klintman M, Strand C, Ahlin C, Beglerbegovic S, Fjällskog ML, Grabau D, Gudlaugsson E, Janssen EA, Lövgren K, Skaland I, Bendahl PO, Malmström P, Baak JP, Fernö M.

PLoS One. 2013 Dec 4;8(12):e81902. doi: 10.1371/journal.pone.0081902. eCollection 2013.


Toward a molecular pathologic classification of urothelial carcinoma.

Sjödahl G, Lövgren K, Lauss M, Patschan O, Gudjonsson S, Chebil G, Aine M, Eriksson P, Månsson W, Lindgren D, Fernö M, Liedberg F, Höglund M.

Am J Pathol. 2013 Sep;183(3):681-91. doi: 10.1016/j.ajpath.2013.05.013. Epub 2013 Jul 1.


G protein-coupled estrogen receptor is apoptotic and correlates with increased distant disease-free survival of estrogen receptor-positive breast cancer patients.

Broselid S, Cheng B, Sjöström M, Lövgren K, Klug-De Santiago HL, Belting M, Jirström K, Malmström P, Olde B, Bendahl PO, Hartman L, Fernö M, Leeb-Lundberg LM.

Clin Cancer Res. 2013 Apr 1;19(7):1681-92. doi: 10.1158/1078-0432.CCR-12-2376.


The Swedish tant: a marker of female aging.

Lövgren K.

J Women Aging. 2013;25(2):119-37. doi: 10.1080/08952841.2013.732826.


Analysis of and prognostic information from disseminated tumour cells in bone marrow in primary breast cancer: a prospective observational study.

Falck AK, Bendahl PO, Ingvar C, Isola J, Jönsson PE, Lindblom P, Lövgren K, Rennstam K, Fernö M, Rydén L.

BMC Cancer. 2012 Sep 11;12:403. doi: 10.1186/1471-2407-12-403.


Global H3K27 trimethylation and EZH2 abundance in breast tumor subtypes.

Holm K, Grabau D, Lövgren K, Aradottir S, Gruvberger-Saal S, Howlin J, Saal LH, Ethier SP, Bendahl PO, Stål O, Malmström P, Fernö M, Rydén L, Hegardt C, Borg Å, Ringnér M.

Mol Oncol. 2012 Oct;6(5):494-506. doi: 10.1016/j.molonc.2012.06.002. Epub 2012 Jun 20.


The retinoblastoma gene undergoes rearrangements in BRCA1-deficient basal-like breast cancer.

Jönsson G, Staaf J, Vallon-Christersson J, Ringnér M, Gruvberger-Saal SK, Saal LH, Holm K, Hegardt C, Arason A, Fagerholm R, Persson C, Grabau D, Johnsson E, Lövgren K, Magnusson L, Heikkilä P, Agnarsson BA, Johannsson OT, Malmström P, Fernö M, Olsson H, Loman N, Nevanlinna H, Barkardottir RB, Borg Å.

Cancer Res. 2012 Aug 15;72(16):4028-36. Epub 2012 Jun 15.


DNA methylation analyses of urothelial carcinoma reveal distinct epigenetic subtypes and an association between gene copy number and methylation status.

Lauss M, Aine M, Sjödahl G, Veerla S, Patschan O, Gudjonsson S, Chebil G, Lövgren K, Fernö M, Månsson W, Liedberg F, Ringnér M, Lindgren D, Höglund M.

Epigenetics. 2012 Aug;7(8):858-67. doi: 10.4161/epi.20837. Epub 2012 Jun 18.


Integrated genomic and gene expression profiling identifies two major genomic circuits in urothelial carcinoma.

Lindgren D, Sjödahl G, Lauss M, Staaf J, Chebil G, Lövgren K, Gudjonsson S, Liedberg F, Patschan O, Månsson W, Fernö M, Höglund M.

PLoS One. 2012;7(6):e38863. doi: 10.1371/journal.pone.0038863. Epub 2012 Jun 7.


A molecular taxonomy for urothelial carcinoma.

Sjödahl G, Lauss M, Lövgren K, Chebil G, Gudjonsson S, Veerla S, Patschan O, Aine M, Fernö M, Ringnér M, Månsson W, Liedberg F, Lindgren D, Höglund M.

Clin Cancer Res. 2012 Jun 15;18(12):3377-86. doi: 10.1158/1078-0432.CCR-12-0077-T. Epub 2012 May 2.


CD44 isoforms are heterogeneously expressed in breast cancer and correlate with tumor subtypes and cancer stem cell markers.

Olsson E, Honeth G, Bendahl PO, Saal LH, Gruvberger-Saal S, Ringnér M, Vallon-Christersson J, Jönsson G, Holm K, Lövgren K, Fernö M, Grabau D, Borg A, Hegardt C.

BMC Cancer. 2011 Sep 29;11:418. doi: 10.1186/1471-2407-11-418.


Can tissue microarray-based analysis of protein expression predict recurrence of stage Ta bladder cancer?

Gudjónsson S, Bendahl PO, Chebil G, Höglund M, Lindgren D, Lundberg LM, Lövgren K, Fernö M, Månsson W, Liedberg F.

Scand J Urol Nephrol. 2011 Sep;45(4):270-7. doi: 10.3109/00365599.2011.568956. Epub 2011 Apr 20.


A novel non-toxic combined CTA1-DD and ISCOMS adjuvant vector for effective mucosal immunization against influenza virus.

Eliasson DG, Helgeby A, Schön K, Nygren C, El-Bakkouri K, Fiers W, Saelens X, Lövgren KB, Nyström I, Lycke NY.

Vaccine. 2011 May 23;29(23):3951-61. doi: 10.1016/j.vaccine.2011.03.090. Epub 2011 Apr 8.


Up-regulation of cell cycle arrest protein BTG2 correlates with increased overall survival in breast cancer, as detected by immunohistochemistry using tissue microarray.

Möllerström E, Kovács A, Lövgren K, Nemes S, Delle U, Danielsson A, Parris T, Brennan DJ, Jirström K, Karlsson P, Helou K.

BMC Cancer. 2010 Jun 16;10:296. doi: 10.1186/1471-2407-10-296.


The prognostic value of Ki67 is dependent on estrogen receptor status and histological grade in premenopausal patients with node-negative breast cancer.

Klintman M, Bendahl PO, Grabau D, Lövgren K, Malmström P, Fernö M; South Sweden Breast Cancer Group.

Mod Pathol. 2010 Feb;23(2):251-9. doi: 10.1038/modpathol.2009.167. Epub 2009 Nov 20.


AIB1 is a predictive factor for tamoxifen response in premenopausal women.

Alkner S, Bendahl PO, Grabau D, Lövgren K, Stål O, Rydén L, Fernö M; Swedish and South-East Swedish Breast Cancer Groups.

Ann Oncol. 2010 Feb;21(2):238-44. doi: 10.1093/annonc/mdp293. Epub 2009 Jul 23.


The CD44+/CD24- phenotype is enriched in basal-like breast tumors.

Honeth G, Bendahl PO, Ringnér M, Saal LH, Gruvberger-Saal SK, Lövgren K, Grabau D, Fernö M, Borg A, Hegardt C.

Breast Cancer Res. 2008;10(3):R53. doi: 10.1186/bcr2108. Epub 2008 Jun 17.


Tissue microarray based analysis of prognostic markers in invasive bladder cancer: much effort to no avail?

Liedberg F, Anderson H, Chebil G, Gudjonsson S, Höglund M, Lindgren D, Lundberg LM, Lövgren K, Fernö M, Månsson W.

Urol Oncol. 2008 Jan-Feb;26(1):17-24. doi: 10.1016/j.urolonc.2006.08.021. Epub 2007 Oct 22.


Recurrent gross mutations of the PTEN tumor suppressor gene in breast cancers with deficient DSB repair.

Saal LH, Gruvberger-Saal SK, Persson C, Lövgren K, Jumppanen M, Staaf J, Jönsson G, Pires MM, Maurer M, Holm K, Koujak S, Subramaniyam S, Vallon-Christersson J, Olsson H, Su T, Memeo L, Ludwig T, Ethier SP, Krogh M, Szabolcs M, Murty VV, Isola J, Hibshoosh H, Parsons R, Borg A.

Nat Genet. 2008 Jan;40(1):102-7. Epub 2007 Dec 9.


Epidermal growth factor receptor (EGFR) and the estrogen receptor modulator amplified in breast cancer (AIB1) for predicting clinical outcome after adjuvant tamoxifen in breast cancer.

Dihge L, Bendahl PO, Grabau D, Isola J, Lövgren K, Rydén L, Fernö M.

Breast Cancer Res Treat. 2008 May;109(2):255-62. Epub 2007 Jul 17.


The combined CTA1-DD/ISCOMs vector is an effective intranasal adjuvant for boosting prior Mycobacterium bovis BCG immunity to Mycobacterium tuberculosis.

Andersen CS, Dietrich J, Agger EM, Lycke NY, Lövgren K, Andersen P.

Infect Immun. 2007 Jan;75(1):408-16. Epub 2006 Oct 30.


Brief focal ultrasound with topical anesthetic decreases the pain of intravenous placement in children.

Skarbek-Borowska S, Becker BM, Lovgren K, Bates A, Minugh PA.

Pediatr Emerg Care. 2006 May;22(5):339-45.


The combined CTA1-DD/ISCOM adjuvant vector promotes priming of mucosal and systemic immunity to incorporated antigens by specific targeting of B cells.

Helgeby A, Robson NC, Donachie AM, Beackock-Sharp H, Lövgren K, Schön K, Mowat A, Lycke NY.

J Immunol. 2006 Mar 15;176(6):3697-706.


Ultrasound with topical anesthetic rapidly decreases pain of intravenous cannulation.

Becker BM, Helfrich S, Baker E, Lovgren K, Minugh PA, Machan JT.

Acad Emerg Med. 2005 Apr;12(4):289-95.


Long-standing protection of macaques against cell-free HIV-2 with a HIV-2 iscom vaccine.

Putkonen P, Björling E, Akerblom L, Thorstensson R, Lövgren K, Benthin L, Chiodi F, Morein B, Biberfeld G, Norrby E, et al.

J Acquir Immune Defic Syndr. 1994 Jun;7(6):551-9.


Mechanisms behind the immune response induced by immunostimulating complexes.

Morein B, Villacrés Eriksson M, Akerblom L, Rönnberg B, Lövgren K, Sjölander A.

AIDS Res Hum Retroviruses. 1994;10 Suppl 2:S109-14. Review. No abstract available.


Effects of adjuvants and multiple antigen peptides on humoral and cellular immune responses to gp160 of HIV-1.

Levi M, Rudén U, Birx D, Loomis L, Redfield R, Lövgren K, Akerblom L, Sandström E, Wahren B.

J Acquir Immune Defic Syndr. 1993 Aug;6(8):855-64.


The induction of cell-associated and secreted IL-1 by iscoms, matrix or micelles in murine splenic cells.

Villacres-Eriksson M, Bergström-Mollaoglu M, Kåberg H, Lövgren K, Morein B.

Clin Exp Immunol. 1993 Jul;93(1):120-5.


Immunopotentiation of synthetic oligopeptides by chemical conjugation to iscoms.

Larsson M, Lövgren K, Morein B.

J Immunol Methods. 1993 Jun 18;162(2):257-60.


Immunogenicity in rabbits and monkeys of influenza ISCOMs conjugated with repeated sequences of the Plasmodium falciparum antigen Pf155/RESA.

Sjölander A, Hansson M, Lövgren K, Wåhlin B, Berzins K, Perlmann P.

Parasite Immunol. 1993 Jun;15(6):355-9.


Plasmodium falciparum: the immune response in rabbits to the clustered asparagine-rich protein (CARP) after immunization in Freund's adjuvant or immunostimulating complexes (ISCOMs).

Sjölander A, Ståhl S, Lövgren K, Hansson M, Cavelier L, Walles A, Helmby H, Wåhlin B, Morein B, Uhlén M, et al.

Exp Parasitol. 1993 Mar;76(2):134-45.


Antigen-specific increases in the number of splenocytes expressing MHC class II molecules following restimulation with antigen in various physical forms.

Bergström-Mollaoglu M, Lövgren K, Akerblom L, Fossum C, Morein B.

Scand J Immunol. 1992 Oct;36(4):565-74.


Interactions between immune-stimulating complexes (ISCOMs) and peritoneal mononuclear leucocytes.

Watson DL, Watson NA, Fossum C, Lövgren K, Morein B.

Microbiol Immunol. 1992;36(2):199-203.


High antibody responses in rabbits immunized with influenza virus ISCOMs containing a repeated sequence of the Plasmodium falciparum antigen Pf155/RESA.

Sjölander A, Lövgren K, Ståhl S, Aslund L, Hansson M, Nygren PA, Larsson M, Hagstedt M, Wåhlin B, Berzins K, et al.

Vaccine. 1991 Jun;9(6):443-50.


The ISCOM: an antigen delivery system with built-in adjuvant.

Lovgren K, Morein B.

Mol Immunol. 1991 Mar;28(3):285-6. No abstract available.


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