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Items: 18


The interactome of intact mitochondria by cross-linking mass spectrometry provides evidence for coexisting respiratory supercomplexes.

Liu F, Lössl P, Rabbitts BM, Balaban RS, Heck AJR.

Mol Cell Proteomics. 2018 Feb;17(2):216-232. doi: 10.1074/mcp.RA117.000470. Epub 2017 Dec 8.


Low pH-induced conformational change and dimerization of sortilin triggers endocytosed ligand release.

Leloup N, Lössl P, Meijer DH, Brennich M, Heck AJR, Thies-Weesie DME, Janssen BJC.

Nat Commun. 2017 Nov 22;8(1):1708. doi: 10.1038/s41467-017-01485-5.


Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.

Liu F, Lössl P, Scheltema R, Viner R, Heck AJR.

Nat Commun. 2017 May 19;8:15473. doi: 10.1038/ncomms15473.


Structures of the cyanobacterial circadian oscillator frozen in a fully assembled state.

Snijder J, Schuller JM, Wiegard A, Lössl P, Schmelling N, Axmann IM, Plitzko JM, Förster F, Heck AJ.

Science. 2017 Mar 17;355(6330):1181-1184. doi: 10.1126/science.aag3218. Epub 2017 Mar 16.


Recombinant Expression of the Full-length Ectodomain of LDL Receptor-related Protein 1 (LRP1) Unravels pH-dependent Conformational Changes and the Stoichiometry of Binding with Receptor-associated Protein (RAP).

De Nardis C, Lössl P, van den Biggelaar M, Madoori PK, Leloup N, Mertens K, Heck AJ, Gros P.

J Biol Chem. 2017 Jan 20;292(3):912-924. doi: 10.1074/jbc.M116.758862. Epub 2016 Dec 12.


The diverse and expanding role of mass spectrometry in structural and molecular biology.

Lössl P, van de Waterbeemd M, Heck AJ.

EMBO J. 2016 Dec 15;35(24):2634-2657. Epub 2016 Oct 26. Review.


Deciphering the Interplay among Multisite Phosphorylation, Interaction Dynamics, and Conformational Transitions in a Tripartite Protein System.

Lössl P, Brunner AM, Liu F, Leney AC, Yamashita M, Scheltema RA, Heck AJ.

ACS Cent Sci. 2016 Jul 27;2(7):445-55. doi: 10.1021/acscentsci.6b00053. Epub 2016 Jun 10.


Nucleotide-dependent conformational changes of the AAA+ ATPase p97 revisited.

Schuller JM, Beck F, Lössl P, Heck AJ, Förster F.

FEBS Lett. 2016 Mar;590(5):595-604. doi: 10.1002/1873-3468.12091. Epub 2016 Feb 20.


Combining Amine-Reactive Cross-Linkers and Photo-Reactive Amino Acids for 3D-Structure Analysis of Proteins and Protein Complexes.

Lössl P, Sinz A.

Methods Mol Biol. 2016;1394:109-127. doi: 10.1007/978-1-4939-3341-9_9.


Structural basis for inhibition of TLR2 by staphylococcal superantigen-like protein 3 (SSL3).

Koymans KJ, Feitsma LJ, Brondijk TH, Aerts PC, Lukkien E, Lössl P, van Kessel KP, de Haas CJ, van Strijp JA, Huizinga EG.

Proc Natl Acad Sci U S A. 2015 Sep 1;112(35):11018-23. doi: 10.1073/pnas.1502026112. Epub 2015 Aug 17.


Benchmarking multiple fragmentation methods on an orbitrap fusion for top-down phospho-proteoform characterization.

Brunner AM, Lössl P, Liu F, Huguet R, Mullen C, Yamashita M, Zabrouskov V, Makarov A, Altelaar AF, Heck AJ.

Anal Chem. 2015 Apr 21;87(8):4152-8. doi: 10.1021/acs.analchem.5b00162. Epub 2015 Apr 8.


Lysine conjugation properties in human IgGs studied by integrating high-resolution native mass spectrometry and bottom-up proteomics.

Gautier V, Boumeester AJ, Lössl P, Heck AJ.

Proteomics. 2015 Aug;15(16):2756-65. doi: 10.1002/pmic.201400462. Epub 2015 Apr 29.


Analysis of nidogen-1/laminin γ1 interaction by cross-linking, mass spectrometry, and computational modeling reveals multiple binding modes.

Lössl P, Kölbel K, Tänzler D, Nannemann D, Ihling CH, Keller MV, Schneider M, Zaucke F, Meiler J, Sinz A.

PLoS One. 2014 Nov 11;9(11):e112886. doi: 10.1371/journal.pone.0112886. eCollection 2014.


Simultaneous assessment of kinetic, site-specific, and structural aspects of enzymatic protein phosphorylation.

van de Waterbeemd M, Lössl P, Gautier V, Marino F, Yamashita M, Conti E, Scholten A, Heck AJ.

Angew Chem Int Ed Engl. 2014 Sep 1;53(36):9660-4. doi: 10.1002/anie.201404637. Epub 2014 Jul 9.


CysK2 from Mycobacterium tuberculosis is an O-phospho-L-serine-dependent S-sulfocysteine synthase.

Steiner EM, Böth D, Lössl P, Vilaplana F, Schnell R, Schneider G.

J Bacteriol. 2014 Oct;196(19):3410-20. doi: 10.1128/JB.01851-14. Epub 2014 Jul 14.


Boundaries of mass resolution in native mass spectrometry.

Lössl P, Snijder J, Heck AJ.

J Am Soc Mass Spectrom. 2014 Jun;25(6):906-17. doi: 10.1007/s13361-014-0874-3. Epub 2014 Apr 4.


[Safety and feasibility of intracoronary brachytherapy with the Novoste system within the scope of international multicenter studies].

Silber S, von Rottkay P, Lössl P, Schneider A, Seidel N, Tourlakidou S, Krischke I, Gessler B, Naser K, Bauer A.

Z Kardiol. 2000 Apr;89(4):323-9. German.


[Possibilities of conventional intravenous subtraction angiography].

Weigert F, Lössl P, Eggemann F.

Rontgenblatter. 1984 Jan;37(1):1-7. German.


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