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Items: 35


Diversity of Interneurons in the Dorsal Striatum Revealed by Single-Cell RNA Sequencing and PatchSeq.

Muñoz-Manchado AB, Bengtsson Gonzales C, Zeisel A, Munguba H, Bekkouche B, Skene NG, Lönnerberg P, Ryge J, Harris KD, Linnarsson S, Hjerling-Leffler J.

Cell Rep. 2018 Aug 21;24(8):2179-2190.e7. doi: 10.1016/j.celrep.2018.07.053.


Termination of cell-type specification gene programs by the miR-183 cluster determines the population sizes of low-threshold mechanosensitive neurons.

Peng C, Furlan A, Zhang MD, Su J, Lübke M, Lönnerberg P, Abdo H, Sontheimer J, Sundström E, Ernfors P.

Development. 2018 Sep 25;145(18). pii: dev165613. doi: 10.1242/dev.165613.


Molecular Architecture of the Mouse Nervous System.

Zeisel A, Hochgerner H, Lönnerberg P, Johnsson A, Memic F, van der Zwan J, Häring M, Braun E, Borm LE, La Manno G, Codeluppi S, Furlan A, Lee K, Skene N, Harris KD, Hjerling-Leffler J, Arenas E, Ernfors P, Marklund U, Linnarsson S.

Cell. 2018 Aug 9;174(4):999-1014.e22. doi: 10.1016/j.cell.2018.06.021.


RNA velocity of single cells.

La Manno G, Soldatov R, Zeisel A, Braun E, Hochgerner H, Petukhov V, Lidschreiber K, Kastriti ME, Lönnerberg P, Furlan A, Fan J, Borm LE, Liu Z, van Bruggen D, Guo J, He X, Barker R, Sundström E, Castelo-Branco G, Cramer P, Adameyko I, Linnarsson S, Kharchenko PV.

Nature. 2018 Aug;560(7719):494-498. doi: 10.1038/s41586-018-0414-6. Epub 2018 Aug 8.


Neuronal atlas of the dorsal horn defines its architecture and links sensory input to transcriptional cell types.

Häring M, Zeisel A, Hochgerner H, Rinwa P, Jakobsson JET, Lönnerberg P, La Manno G, Sharma N, Borgius L, Kiehn O, Lagerström MC, Linnarsson S, Ernfors P.

Nat Neurosci. 2018 Jun;21(6):869-880. doi: 10.1038/s41593-018-0141-1. Epub 2018 Apr 23.


Conserved properties of dentate gyrus neurogenesis across postnatal development revealed by single-cell RNA sequencing.

Hochgerner H, Zeisel A, Lönnerberg P, Linnarsson S.

Nat Neurosci. 2018 Feb;21(2):290-299. doi: 10.1038/s41593-017-0056-2. Epub 2018 Jan 15.


STRT-seq-2i: dual-index 5' single cell and nucleus RNA-seq on an addressable microwell array.

Hochgerner H, Lönnerberg P, Hodge R, Mikes J, Heskol A, Hubschle H, Lin P, Picelli S, La Manno G, Ratz M, Dunne J, Husain S, Lein E, Srinivasan M, Zeisel A, Linnarsson S.

Sci Rep. 2017 Nov 27;7(1):16327. doi: 10.1038/s41598-017-16546-4.


Alternative TSSs are co-regulated in single cells in the mouse brain.

Karlsson K, Lönnerberg P, Linnarsson S.

Mol Syst Biol. 2017 May 11;13(5):930. doi: 10.15252/msb.20167374.


Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells.

La Manno G, Gyllborg D, Codeluppi S, Nishimura K, Salto C, Zeisel A, Borm LE, Stott SRW, Toledo EM, Villaescusa JC, Lönnerberg P, Ryge J, Barker RA, Arenas E, Linnarsson S.

Cell. 2016 Oct 6;167(2):566-580.e19. doi: 10.1016/j.cell.2016.09.027.


Single-Cell Transcriptomics Reveals that Differentiation and Spatial Signatures Shape Epidermal and Hair Follicle Heterogeneity.

Joost S, Zeisel A, Jacob T, Sun X, La Manno G, Lönnerberg P, Linnarsson S, Kasper M.

Cell Syst. 2016 Sep 28;3(3):221-237.e9. doi: 10.1016/j.cels.2016.08.010. Epub 2016 Sep 15.


A PBX1 transcriptional network controls dopaminergic neuron development and is impaired in Parkinson's disease.

Villaescusa JC, Li B, Toledo EM, Rivetti di Val Cervo P, Yang S, Stott SR, Kaiser K, Islam S, Gyllborg D, Laguna-Goya R, Landreh M, Lönnerberg P, Falk A, Bergman T, Barker RA, Linnarsson S, Selleri L, Arenas E.

EMBO J. 2016 Sep 15;35(18):1963-78. doi: 10.15252/embj.201593725. Epub 2016 Jun 28.


Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system.

Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcão A, Xiao L, Li H, Häring M, Hochgerner H, Romanov RA, Gyllborg D, Muñoz Manchado A, La Manno G, Lönnerberg P, Floriddia EM, Rezayee F, Ernfors P, Arenas E, Hjerling-Leffler J, Harkany T, Richardson WD, Linnarsson S, Castelo-Branco G.

Science. 2016 Jun 10;352(6291):1326-1329. doi: 10.1126/science.aaf6463.


Presymptomatic activation of the PDGF-CC pathway accelerates onset of ALS neurodegeneration.

Lewandowski SA, Nilsson I, Fredriksson L, Lönnerberg P, Muhl L, Zeitelhofer M, Adzemovic MZ, Nichterwitz S, Lawrence DA, Hedlund E, Eriksson U.

Acta Neuropathol. 2016 Mar;131(3):453-64. doi: 10.1007/s00401-015-1520-2. Epub 2015 Dec 19.


Gene expression analysis of skin grafts and cultured keratinocytes using synthetic RNA normalization reveals insights into differentiation and growth control.

Katayama S, Skoog T, Jouhilahti EM, Siitonen HA, Nuutila K, Tervaniemi MH, Vuola J, Johnsson A, Lönnerberg P, Linnarsson S, Elomaa O, Kankuri E, Kere J.

BMC Genomics. 2015 Jun 25;16:476. doi: 10.1186/s12864-015-1671-5.


Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors.

Bose R, Spulber S, Kilian P, Heldring N, Lönnerberg P, Johnsson A, Conti M, Hermanson O, Ceccatelli S.

Cell Death Dis. 2015 Jun 18;6:e1793. doi: 10.1038/cddis.2015.159.


Brain structure. Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq.

Zeisel A, Muñoz-Manchado AB, Codeluppi S, Lönnerberg P, La Manno G, Juréus A, Marques S, Munguba H, He L, Betsholtz C, Rolny C, Castelo-Branco G, Hjerling-Leffler J, Linnarsson S.

Science. 2015 Mar 6;347(6226):1138-42. doi: 10.1126/science.aaa1934. Epub 2015 Feb 19.


Unbiased classification of sensory neuron types by large-scale single-cell RNA sequencing.

Usoskin D, Furlan A, Islam S, Abdo H, Lönnerberg P, Lou D, Hjerling-Leffler J, Haeggström J, Kharchenko O, Kharchenko PV, Linnarsson S, Ernfors P.

Nat Neurosci. 2015 Jan;18(1):145-53. doi: 10.1038/nn.3881. Epub 2014 Nov 24.


Topographical transcriptome mapping of the mouse medial ganglionic eminence by spatially resolved RNA-seq.

Zechel S, Zajac P, Lönnerberg P, Ibáñez CF, Linnarsson S.

Genome Biol. 2014;15(10):486.


Base preferences in non-templated nucleotide incorporation by MMLV-derived reverse transcriptases.

Zajac P, Islam S, Hochgerner H, Lönnerberg P, Linnarsson S.

PLoS One. 2013 Dec 31;8(12):e85270. doi: 10.1371/journal.pone.0085270. eCollection 2013.


Quantitative single-cell RNA-seq with unique molecular identifiers.

Islam S, Zeisel A, Joost S, La Manno G, Zajac P, Kasper M, Lönnerberg P, Linnarsson S.

Nat Methods. 2014 Feb;11(2):163-6. doi: 10.1038/nmeth.2772. Epub 2013 Dec 22.


NCoR controls glioblastoma tumor cell characteristics.

Heldring N, Nyman U, Lönnerberg P, Onnestam S, Herland A, Holmberg J, Hermanson O.

Neuro Oncol. 2014 Jan;16(2):241-9. doi: 10.1093/neuonc/not214. Epub 2013 Dec 12.


Highly multiplexed and strand-specific single-cell RNA 5' end sequencing.

Islam S, Kjällquist U, Moliner A, Zajac P, Fan JB, Lönnerberg P, Linnarsson S.

Nat Protoc. 2012 Apr 5;7(5):813-28. doi: 10.1038/nprot.2012.022.


Characterization of the single-cell transcriptional landscape by highly multiplex RNA-seq.

Islam S, Kjällquist U, Moliner A, Zajac P, Fan JB, Lönnerberg P, Linnarsson S.

Genome Res. 2011 Jul;21(7):1160-7. doi: 10.1101/gr.110882.110. Epub 2011 May 4.


Rapid genome sequencing with short universal tiling probes.

Pihlak A, Baurén G, Hersoug E, Lönnerberg P, Metsis A, Linnarsson S.

Nat Biotechnol. 2008 Jun;26(6):676-84. doi: 10.1038/nbt1405. Epub 2008 May 25.


Whole-genome expression profiling through fragment display and combinatorial gene identification.

Metsis A, Andersson U, Baurén G, Ernfors P, Lönnerberg P, Montelius A, Oldin M, Pihlak A, Linnarsson S.

Nucleic Acids Res. 2004 Sep 8;32(16):e127.


Recent evolutionary origin within the primate lineage of two pseudogenes with similarity to members of the transforming growth factor-beta superfamily.

Eketjäll S, Jörnvall H, Lönnerberg P, Kobayashi S, Ibáñez CF.

Cell Mol Life Sci. 2004 Feb;61(4):488-96.


Novel, testis-specific mRNA transcripts encoding N-terminally truncated choline acetyltransferase.

Lönnerberg P, Ibáñez CF.

Mol Reprod Dev. 1999 Jul;53(3):274-81.


Regulatory region in choline acetyltransferase gene directs developmental and tissue-specific expression in transgenic mice.

Lönnerberg P, Lendahl U, Funakoshi H, Arhlund-Richter L, Persson H, Ibáñez CF.

Proc Natl Acad Sci U S A. 1995 Apr 25;92(9):4046-50.


Engineering cells to secrete growth factors.

Ebendal T, Lönnerberg P, Pei G, Kylberg A, Kullander K, Persson H, Olson L.

J Neurol. 1994 Dec;242(1 Suppl 1):S5-7. Review.


Role of variable beta-hairpin loop in determining biological specificities in neurotrophin family.

Ilag LL, Lönnerberg P, Persson H, Ibáñez CF.

J Biol Chem. 1994 Aug 5;269(31):19941-6.


Beta-nerve growth factor influences the expression of androgen-binding protein messenger ribonucleic acid in the rat testis.

Lönnerberg P, Söder O, Parvinen M, Ritzén EM, Persson H.

Biol Reprod. 1992 Sep;47(3):381-8.


Stage- and cell-specific expression of cyclic adenosine 3',5'-monophosphate-dependent protein kinases in rat seminiferous epithelium.

Lönnerberg P, Parvinen M, Jahnsen T, Hansson V, Persson H.

Biol Reprod. 1992 Jun;46(6):1057-68.


Expression of beta-nerve growth factor and its receptor in rat seminiferous epithelium: specific function at the onset of meiosis.

Parvinen M, Pelto-Huikko M, Söder O, Schultz R, Kaipia A, Mali P, Toppari J, Hakovirta H, Lönnerberg P, Ritzén EM, et al.

J Cell Biol. 1992 May;117(3):629-41.


Developmental and regional expression of basic fibroblast growth factor mRNA in the rat central nervous system.

Ernfors P, Lönnerberg P, Ayer-LeLievre C, Persson H.

J Neurosci Res. 1990 Sep;27(1):10-5.


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